대학생의 수면양상과 수면장애요인에 관한 연구

김유진,박미경,박이랑,이보람,이혜림,전선미,양난영,김수지,이자형 이화여자대학교 간호과학대학 2004 이화간호학회지 Vol.- No.38

The results of this Study are as follows:33.6% of all participants have insomnia; 22.5% of those who have insomnia are DIS(difficulty in initiating sleep), 17.3% are DMS(difficulty returning to sleep once awakened) and 7.0% awakened too early. 3 4.8% experience sleepiness during daytime. Type 1, experiencing insomnia and sleepi ness during daytime together, is 12.0%, Type 2, with insomnia only, is 21.6%, Type 3, with sleepiness during daytime only, is 22.8% and 43.5% experience no sleeping disturbances. After studying only those with 3 types of sleeping disturbances, it is found that the most common cause of such disturbance is stress 88.4%, anxiety 56.0%, no apparent reason 33.8%, anxiety/fear/terror 29.3%, hurry 23.6%, alcohol/caffeine 16.9%, bedroom tem perature 11.1%, urination during nighttime and persons living together 10.7%, noise from inside 8.9%, illumination 8.0%, and pain/itch 5.8%. The one group revealed significant differences in residential environment(p=0.003). Sex, age, education level, medicine, monthly earning revealed no meaningful differences. Of sleeping behavior, mean duration of sleep latency(p=0.000), whether or not feeling freshness(p=0.000), whether taking enough sleep(p=0.029), whether taking regular sleep(p=0.005) showed significant differences depending on whether or not having insomnia, and mean duration of sleep time, time to sleep, time of rising, whether taking naps did not reveal significant differences. Of sleep behavior, time to sleep(p=0.000), whether taking naps(p=0.000), indicated significant differences. Of sleeping behavior, mean duration of sleep latency(p=0.000), whether or not feeling freshness(p=0.000), and whether taking enough sleep(p=0.000), time of going to bed (p=0.002), whether or not taking nap(p=0.000), whether or not taking regular sleep(p=0.010) indicated significant differences among the sleeping disturbance types.

관상동맥 질환에서 SDF-1α의 농도

김보영,박용규,박형서,노상필,정승현,이유선,이정우,이재환,최시완,정진옥,성인환 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

Atherosclerosis is now viewed as an inflammatory disease of the vascular system. Expression of several chemokines, including monocyte chemoattractant protein(MCP)-1, MCP-4, RANTES(regulated on activation normal T-cell expressed and secreted), and interleukin-8(IL-8) are increased in human atherosclerotic plaques compared with normal vessels. They are involved in the pathogenesis of atherosclerosis and plaque rupture by activating and directing leukocytes into the atherosclerotic lesions. However, some are involved in homeostatic functions such as normal leukocyte traffic and growth regulation. SDF-la is a multi-functional cytokine that is involved in myelogenesis, hematopoiesis, angiogenesis and injured gastric mucosal regeneration in the gastric ulcer patient. SDF-la is recently shown to be highly expressed in atherosclerotic plaques and a potent platelet agonist. At least in high concentrations, SDF-la may mediate antiinflammatory and matrix stabilizing effects in unstable angina. Many studies are going on to know the function of SDF-la in coronary artery diseases. I investigated the difference of the plasma level of SDF-la between control group and coronary artery disease group. Total 75 subjects were enrolled. The diagnosis of coronary artery disease was confirmed in all patients by coronary angiography. Control subjects in this study were confirmed normal by coronary angiography. Clinical profile and risk factors were also reviewed. Control subjects in this study were 27 (M=10, F=17). Plasma for the study was collected before the angiography and centrifuged. SDF-la analysis was performed by ELISA. Plasma level of SDF-la is significantly increased in patients with stable angina(n=20) and unstable angina group(n=28) compared with healthy control group(n=27). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases. In this study, plasma level of SDF-la is increased in patients with stable angina and unstable angina groups compared with healthy control group(P<0.05). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases.

대학생의 취업스트레스와 자아존중감, 자아효능감, 외모관리행동의 관계

김보라,김유진,김지희,노혜진,오승희,홍지혜,황윤희,박선아 水原大學校 2016 論文集 Vol.30 No.-

Purpose: Many university students are under a lot of job-seeking stress because the employment rate is low. This study sought to determine the relationship between job-seeking stress, self esteem, self efficacy and appearance management behavior amongst university students focusing on nursing. Methods: This descriptive correlational study evaluated the relationships between job-seeking stress, self esteem, self efficacy and appearance management behavior of 340 university students was conducted between September 1 and October 5, 2015. Results: The correlational analysis between job-seeking stress, self esteem, self efficacy and appearance management behavior revealed a negative correlation between job-seeking stress, self esteem and self efficacy and a positive correlation between job-seeking stress and appearance management behavior. In addition, age also correlated with self esteem, self efficacy and appearance management behavior. Conclusion: Stress correlated with self esteem and self efficacy and appearance management behavior. Therefore job-seeking stress may be reduced through not only self esteem and self efficacy enhancement programs but also management according to age.

다결정 니켈표면과 산소 기체와의 상호 작용

안운선,이순보,부진효,박유용 성균관대학교 기초과학연구소 1986 論文集 Vol.37 No.2

The interaction of the gaseous oxygen molecule with polycrystalline nickel surface has been studied by the XPS through the wide range above the room temperature. For relatively lower oxygen exposure, only an O(1s) peak was observed at 530.2 eV, which is associated with the dissociative adsorption. On the other hand, with increasing oxygen exposures, two peaks was appeared at 529.7eV and 531.3eV. These peaks are attributed to nickel oxide and Ni_2O_3, respectively. The latter oxide is ascribed due to the excess adsorption over the NiO stoichiometry. However at high temperatures above 423K, the dissociative adsorption and oxidation was found to take place simultaneously. As a whole, through these XPS study it is found that the interaction of the oxygen with the polycrystalline nickel surface commences through three steps: the fast dissociative adsorption following slow initiation process, rapid oxidation corresponding to the epitaxial NiO formation, and finally the bulk oxide formation.

Papain 유도 호흡기 염증모델에서 인삼패독산(人蔘敗毒散)의 항염증 효과

우연주, 유준상, 이동혁, 서진우, 김주희, 권보인 상지대학교 한의학연구소 2023 尙志韓醫論文集 Vol.11 No.1

Objectives: Insampaedok-san and its main components have been used for treatment of fever, joint pain, cough, headache and pain. Using a respiratory inflammation model, we intend to investigate the anti-inflammatory effect and its mechanism of Insampaedok-san. Methods: We induced the actue respiratory inflammatory mouse model by papain treatment. BALB/C mice (female, 8 weeks old) were divided into three groups as follows: saline control (SC): papain treated group (vehicle): papain and Insampaedok-san (200mg/kg) treated group (n=4). To demonstrate the ani-inflammatory effect of Insampaedok-san water extracts, inflammatory cell infiltration was evaluated in bronchoalveolar lavage fluid (BALF) and nasal lavage fluid (NALF). In addition, immunogloblin (Ig)-E level was measured by using ELISA. Results: Insampaedok-san extracts administration decreased inflammatory cell infiltration in BALF and NALF. Especially, eosinophil infiltration was dramatically reduced. Furthermore, total Ig-E level was diminished in BALF and serum by Insampaedok-san administration. Conclusions: Our findings revealed Insampaedok-san extracts have anti-inflammatory effects by inhibiting inflammatory cell, especially eosinophil infiltration and Ig-E level.

Original Articles : Clinical features and treatment efficacy of peginterferon alfa plus ribavirin in chronic hepatitis C patients coinfected with hepatitis B virus

( Yu Jin Kim ),( Jin Woo Lee ),( Yun Soo Kim ),( Sook Hyang Jeong ),( Young Seok Kim ),( Hyung Joon Yim ),( Bo Hyun Kim ),( Chun Kyon Lee ),( Choong Kee Park ),( Sang Hoon Park ) 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.3

Background/Aims: Cross-sectional studies have documented that 2-10% of patients who are chronically infected with hepatitis C virus (HCV) are also positive for hepatitis B virus (HBV) surface antigen (HBsAg). Data related to HCV-HBV coinfection are lacking in Korea. This study evaluated the clinical characteristics, the treatment efficacy of peginterferon alfa plus ribavirin, and the changes induced by such treatment in HBV status in chronic hepatitis C (CHC) patients coinfected with HBV. Methods: Eighteen (2.37%) HBsAg-positive CHC patients were selected from among the 758 subjects from the K(G)yeonggi-Incheon Peginterferon alfa and ribavirin in chronic hepatitis C Treatment (KIPECT) study, which evaluated the treatment efficacy and safety of peginterferon alfa plus ribavirin in CHC patients. Data on changes in the status of HBV infections were obtained. Results: HCV genotype 1b was the most common (44%). The overall sustained virologic response rate was 72% in all patients, and 60% and 87.5% in genotypes 1 and 2, respectively. Two of the 18 patients were positive for HBeAg, and 15 had baseline HBV DNA level of less than 2,000 IU/mL. Two of the three whose levels exceeded this threshold showed no detectable DNA after treatment. After the completion of treatment, serum HBV DNA levels were increased in the two patients whose baseline HBV DNA levels were less than 2,000 IU/mL. Conclusions: The prevalence of HBV coinfection in CHC patients was 2.37% and most of the patients were inactive carriers. The treatment efficacy was similar to that of HCV mono-infection. Reactivation of HBV replication was observed in some patients after CHC treatment. (Korean J Hepatol 2011;17:199-205)

Role of the modified Saengmaeksan(mSMS) in L-NAME-induced hypertension model

Jin Ki Jung,Hobin Moon,Won Hee Nam,Yun-Hwan Kang,Se-Jin Kim,Young Mi Seok,Hyun Hee Leem,Ji-Woon Jeong,Yu Jin Park,Min Ju Kim,Chae Suk Ra,Jiyoung Seo,Hye Won Shin,Bo Gyung Jang,Hyo Jung Kim 한국실험동물학회 2022 한국실험동물학회 학술발표대회 논문집 Vol.2022 No.7

Quantitative CT Measurements of Emphysema in Never Smoker COPD

( Yu Il Kim ),( Ji Sun Oh ),( Sun Min Kim ),( Hyun Wook Kang ),( Jin Yeong Yu ),( Bo Ram Lee ),( Woo Jin Kim ),( Hee Jung Ban ),( Yong Soo Kwon ),( In Jae Oh ),( Kyu Sik Kim ),( Young Chul Kim ),( Sun 대한결핵 및 호흡기학회 2012 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.114 No.-

Introduction: Although cigarette smoke is the most important risk factor for COPD, never smokers also comprise important proportion of COPD. There is limited knowledge about CT quantitative measurement of emphysema in never smoker COPD. Objectives: To describe the differences of quantitative measurement of emphysema between never smoker and ever smoker COPD. Methods: We included patients with COPD who were older than 45 years. All subjects underwent spirometry and multi-dectector computed tomography examination. The MDCT images were analyzed to determine total emphysema (defined as the percentage of low attenuation areas [LAA%] less than -950 Hounsfield units; %LAA950). Differences between never and ever smokers were examined. Results: A total of 49 COPD patients were inclued; 23 never smokers and with 25 ever smokers The mean %LAA950 was 0.5 (SD, 1.1) and 15.3 (SD, 7.0) in never and ever smoker COPD cases, respectively. %LAA950 was significantly lower in never smokers with COPD compared to ever smokers (p<0.001). In the multivariate analysis adjusting age, sex and lung volumes, smoking status was the significant factor to determine the severity of emphysema. Conclusions: Never smokers with COPD have less CT emphysema than smokers. This difference in radiographic expression may in part explain the different features of COPD according to smoking status.

All-solid-state flexible supercapacitors fabricated with bacterial nanocellulose papers, carbon nanotubes, and triblock-copolymer ion gels.

Kang, Yu Jin,Chun, Sang-Jin,Lee, Sung-Suk,Kim, Bo-Yeong,Kim, Jung Hyeun,Chung, Haegeun,Lee, Sun-Young,Kim, Woong American Chemical Society 2012 ACS NANO Vol.6 No.7

<P>We demonstrate all-solid-state flexible supercapacitors with high physical flexibility, desirable electrochemical properties, and excellent mechanical integrity, which were realized by rationally exploiting unique properties of bacterial nanocellulose, carbon nanotubes, and ionic liquid based polymer gel electrolytes. This deliberate choice and design of main components led to excellent supercapacitor performance such as high tolerance against bending cycles and high capacitance retention over charge/discharge cycles. More specifically, the performance of our supercapacitors was highly retained through 200 bending cycles to a radius of 3 mm. In addition, the supercapacitors showed excellent cyclability with C(sp) (~20 mF/cm(2)) reduction of only <0.5% over 5000 charge/discharge cycles at the current density of 10 A/g. Our demonstration could be an important basis for material design and development of flexible supercapacitors.</P>

비침습형 휴대용 뇌-컴퓨터 인터페이스를 위한 전전두엽에서의 fNIRS 뇌이미징 신호 분류

유진우(Yu Jin Woo),김보민(Kim Bo Min),이도영(Lee Do Young),김승현(Kim Seung Hyeon),이유현(Lee Yu Hyun),임성호(Lim Sung-Ho),김경수(Kim Kyungsoo),최지웅(Choi Ji-Woong) 한국통신학회 2018 한국통신학회 학술대회논문집 Vol.2018 No.1