妊娠 第9 個月에 倂發한 Hirschsprung's Disease의 1例

申鉉卓,張潤錫,申旻雨,朴吉秀 大韓産婦人科學會 1963 大韓産婦人科學會雜誌 Vol.6 No.6

편도체 중심핵의 가역적 손상이 공포의 습득과 표현에 미치는 영향

신선희,김기석,김현택 한국심리학회 한국심리학회지 생물 및 생리 Vol.4 No.1

지난 수년간 여러 보고들은 편도체가 무조건공포 및 조건공포에 관여함을 시사해 왔는며 근래에 들어서는 이 구조물을 하부핵군으로 구분하여 기능적으로 특정화하려는 노력이 시도되고 있다. 편도체 중심핵은 이들 하부핵군들 중 여러 가지 공포반응을 지배하는 뇌간 영역들에 가장 광범위한 투사를 하기 때문에 공포의 표현에 관여할 것이라는 견해가 지배적이다. 그러나 공포의 습득에서 편도체 중심핵의 역할에 대해서는 상반된 주장들이 있다. 따라서 본 연구는 공포나 불안을 측정하는 여러 동물모형중에서 상승된 경악반응 절차를 사용하여, 편도체 중심핵의 가역적 손상이 공포의 습득과 표현에 어떠한 영향을 미치는지 살펴보고 이를 통해 공포학습에서 편도체 중심핵의 역할을 알아보고자 하였다. 공포의 습득장면과 표현장면을 분리하여 연구하기 위해 국소마취제 리도카인이 사용되었다. 실험집단으로는 리도카인의 미세 주입 시기를 훈련 직전과 검사 직전으로 구분한, 리도카인-식염수 집단, 식염수-리도카인집단, 식염수-식염수집단, 리도카인-리도카인집단이 사용되었다. 실험결과, 훈련전이나 혹은 검사전에 리도카인을 투여받은 피험동물들은 경악반응의 상승을 거의 보이지 않았다. 그러나 이같은 결과를 상황의존적 인출실패 때문이라고 볼 수 없다. 왜냐하면 리도카인-리도카인 집단 역시 상승된 경악반응을 보이지 않았기 때문이다. 따라서 본 연구의 결과는 편도체 중심핵이 공포의 표현뿐만아니라 공포의 습득에도 중대하게 관여함을 시사한다. For the past years there have been not a few reports that suggested the amygdala is responsible for conditioned fear as well as for unconditioned fear. In recent years the attempts have been made to divide the amygdala into several sub-structures and to specify each of them in view of its function. And it is generally accepted that among the sub-divisions the central amygdala takes part in the expression of fear because it projects its fibers most expensively to the brainstem areas which control a variety of fear responses. But with respect to the acquisition of fear, the role of the central amygdala is of much controversy. The present study is therefore to investigate what effects the reversible lesions of the central amygdaloid nucleus have on the acquisition and the expression of fear, using the fear-potentiated startle paradigm as an animal model for measuring fear or anxiety, and accordingly to identify the role of the centra amygdala in fear conditioning. To separate conditioning trial from test trial, the local anesthetic lidocaine was used, and so the experiment consisted of four groups on the basis of lidocaine micro-injected right before the conditioning trial or just before the test trial: lidocaine-saline group, saline-lidocaine group, saline-saline group, and lidocaine-lidocaine group. As a result, the animals which had been lidocaine-injected either before the conditioning trial or before the test trial, showed little increase in the startle responses. But the result cannot be due to the state dependent retrieval failure since the lidocaine-lidocaine group showed no fear-potentiated startle responses either. Thus, the result of the study strongly suggests that the central amygdala is involved not only in the expression of fear but also in the acquisition of fear.

대학생들의 학교생활 적응에 관한 연구

신은숙,김현덕,민무숙 順天鄕大學校 學生生活硏究所 1995 學生生活硏究 Vol.2 No.-

This study examines college students' adjustment to their campus lives. The hypothesis of this research is that the school experiences of college students are different depending on the background of those students, and these influence their adjustment to their lives in college. The study sample included 293 students who are freshmen, sophomore, and junior students at Soonchunhyang University in Onyang City. First, the school experiences were measured with respect to six background variables from two points of view: the extents of their use of school facilities and hours of staying on campus. School adjustment score were also measured depending on the six background variables of students. Four areas of adjustment were also attained: academic adjustment, Social adjustment, personl_emotional adjustment, and attachment. These four facets were analyzed with relation to the school experiences. Statistical analysis showed that the level of school adjustment were different depending on three background variables, such as gender, economic condition, and commuting distance. That is, the male students showed higher degree of school adjustment than the females; the students with poor economic condition showed the lowest adjustment score; those who are living in the university dormitory were proved to be generally competent in adjusting themselves in campus life. Furthermore, the subscores of school adjustment were different depending on all of six background variabls. The statistical analysis also showed that there existed no relationship between the adjustment level and the frequencies of the school facilities. However, the hours of staying on campus showed a positive relationship with the adjustment. This was variant depending on gender and commuting distance. That is, the male students stayed longer on campus and showed higher adjustment, scores than the female students; the students living in the university dormitory stayed longer in campus and showed higher adjustment scores than the commuting students from long distance, such as Seoul, and Taejeon.

석면함유 슬레이트 지붕 물받이 퇴적물 중 석면 섬유 함유율

임지현,한솔민,김현석,신유민,박시은,허정윤,김민영,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

This study attempted to determine the degree of asbestos release from the aging slate roof by comparing the asbestos content in the slate roof rain gutter with a colored steel plate (tin plate) over the slate roof. Four slate roof houses located in Haengmok-ri, Asan-si, Chungcheongnam-do, and one house constructed with a colored steel plate on the slate roof were selected to collect the sediment of the roof rain gutter. The asbestos fiber content was calculated by a point counting method using a polarization microscope after pretreatment with conversion treatment and hydrochloric acid treatment. The average asbestos content of the four slate roof rain gutter were 1.89%. However, asbestos was not detected in the Slate covering roof rain gutter, which were constructed on the slate roof. Asbestos fiber content was the highest at 2.89% in the slate roof rain gutter installed in 1976, followed by 2.44% in 1953. From the above results, it is necessary to minimize secondary damage as asbestos fibers released from slate roof houses to the surrounding atmosphere or leaked from slate roofs as rainwater may cause soil pollution and seriously affect residents' health. Although covering with colored steel plates (tin plates) has been shown to prevent the leakage of asbestos fibers to some extent, it is believed that a policy alternative to remove the slate roof as soon as possible is needed to solve the fundamental problem.

연구개의 이소성 뇌조직 - 1예 보고-

최현주,이연수,김영신,이교영,강창석,심상인 대한병리학회 1998 Journal of Pathology and Translational Medicine Vol.32 No.11

내동정맥루술후의 수지운동이 동정맥루의 혈류와 개존에 미치는 영향

신현석,조원현,이성문,우성구,김현철 大韓脈管外科學會 1995 大韓脈管外科學會誌 Vol.11 No.1

사인에 의한 즉시형 과민반응의 억제 효과

신태용,염정열,김원,김현미,박해정,장진이,조성룡,채병숙 우석대학교 생명과학연구소 1998 생명과학연구소 논문집 Vol.2 No.-

We investigated the effect of aqueous extract of Ammomum xanthioides(AXAE) on immediate hypersensitivity. AXAE inhibited systemic anaphylaxis induced by compound 48/80 in mice. AXAE inhibited serum histamine levels induced by compound 48/80 in mice. Moreover, AXAE dose-dependently inhibited histamine release in peritoneal mast cells activated by compound 48/80. These results indicate that the AXAE may be benificial in the regulation of immediate type allergic reaction.

조직의 환경통제모형에 의한 산업재해의 구조적 발생에 관한 사례 연구

申炳玹,姜錫宰 홍익대학교 경영연구소 1989 경영연구 Vol.13 No.-

지역아동센터 이용만족도에 영향을 미치는 요인 : 광주광역시 북구 지역을 중심으로

신웅철, 좌현숙 호남대학교 대학원 2014 호남대학교 대학원 논문집 Vol.9 No.-

This study is aimed to prepare for policy alternatives so as to improve further user satisfaction of community child care center along with supplying effective services in managing the center by analyzing impacted factors influencing user satisfaction of children user the centers. For achieving this research purposes, the study carried out questionnaires on the user satisfaction at community child care centers after selecting 13 centers located in the Buk-gu of Gwangju Metropolitan City. The results of this study are the following things. First, as long as using hour per day is, high satisfaction degrees are appeared on the operation program. Second, also children’s satisfaction of the environment and sanitation appeared to have great influence on user satisfaction. Third, satisfaction of relations with teachers are highest among all factors influencing to user satisfactions. Fourth, satisfaction degrees are observed differently according to friend relations. Therefore, it should place emphasis on developing various and children’s preference programs in order to improve user satisfaction of community child care center, moreover, this study suggests that safe and pleasant environment development, regular and continuous teacher education and improvement of relations between children using community child care centers is important. Keywords : Customer satisfaction, Community childcare center

광주광역시 치매의 유병률과 위험인자의 도시-농촌 지역 비교

신일선,김재민,윤진상,김석재,양수진,김웅장,이승현,강순아,곽지영,이형영 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.6

연구목적 : 본 연구의 목적은 광주광역시의 도시 및 농촌 지역에 거주하는 노인에서 치매의 유병률과 위험인자를 조사하고자 하였다. 부가적으로 이 두 지역간에 치매의 유병률과 위험인자를 비교하고자 하였다. 방 법 : 광주광역시의 전형적인 도시와 농촌지역의 65세 이상의 노인(N=1,598)을 대상으로, 2단계의 역학연구를 수행하였다. 1차 선별 단계에서는 38명의 훈련된 연구보조원이 대상노인을 면담하여, 사회인구학적 특징을 조사하고 한국판 간이정신상태검사(Korean version of Mini-Mental State Examination ; MMSE-K)로 평가하였다. 2차 임상 진단 단계에서는 1차 단계에서 MMSE-K 점수가 24점 이하인 노인(N=431)을 대상으로, 전문연구팀의 임상적 평가를 통해 치매를 진단하고 원인질환별로 알쯔하이머병(Alzheimer's disease ; AD), 혈관성 치매(vascular dementia ; VaD) 및 기타 치매로 분류하였다. 대상노인에서 치매의 유병률을 측정한 후, 광주광역시 전체 노인의 연령보정 유병률을 산출하였다. 전체 대상에서 AD의 위험인자를 조사한 후, 도시와 농촌군으로 나누어 분석을 다시 시행하였다. 결 과 : 1차 및 2차 단계의 참가율은 각각 71.0%(N=1,134) 및 83.2%(N=410) 였다. 연구 참여 노인(N=1,134)에서 전체 치매, AD 및 VaD의 유병률은 최소 각각 9.7%, 5.2%, 1.8%였다. 광주광역시 전체 노인의 연령 보정 유병률은 각각 10.7%, 5.7%, 1.9%인 것으로 산출되었다. AD의 독립 위험인자는 고령, 여성, 무학이었다. 도시와 농촌에 따른 유병률의 차이는 파악되지 않았다. 그러나 AD의 위험인자는 지역에 따라 차이가 있었다. 도시 노인에게는 무학만이, 농촌 노인에게는 고령과 여성인 경우가 독립 위험인자였다. 결 론 : 광주광역시 노인에서 치매의 유병률은 높았고, 이는 국내 다른 지역에서 수행된 선행연구 결과와 유사하였다. 알쯔하이머형 치매의 위험인자는 도시와 농촌에 따라 다른 결과를 보였다. 본 연구 결과는 한국에서의 치매의 실태를 반영하며, 치매의 적절한 관리와 예방을 위해서는 지역성 특성이 고려되어야 함을 시사한다. Objectives : The purpose of this study was to investigate the prevalence rate and risk factors of dementia in an urban and a rural sample of older persons in the metropolitan Kwangju area, Republic of Korea. In addition, the prevalence rate and risk factors of dementia between the two samples were compared. Methods : A two-phase epidemiological study of residents aged 65 or over(N=1,598) was conducted in a highly developed, urban and a non-contiguous, poorly developed, rural area of metropolitan Kwangju. In the first(screening) phase, 38 trained research assistants collectively peformed in-home interviews for all participants. Detailed sociodemographic characteristics were gathered and the Korean version of Mini-Mental State Examination (MMSE-K) was administered. In the second (diagnosing) phase, diagnosis of dementia was established for those scoring 24 or less on the MMSE-K in the screening phase(N=431), and etiological types of dementia were classified to Alzheimer's disease(AD), vascular dementia(VaD) or miscellanous type by two teams of experts. Prevalence rate of dementia was determined in the participants, and age-standardized prevalence rate adjusted by age distribution in metropolitan Kwangju was estimated. For AD, the risk factors were investigated in all participants, and analyses were repeated for the urban and rural samples separately. Results : The participating rates in the first and second phases were 71.0%(N=1,134) and 83.2%(N=410), respectively. In the participants, the prevalence rates of dementia(all types), AD and VaD were 9.7%, 5.2% and 1.8%, respectively. The age-standardized prevalence rates were 10.7%, 5.7% and 1.9%, respectively. Aging, female gender and no education(complete lack of formal education) were identified as independent risk factors for AD. No difference between the urban and rural samples was observed in the prevalence rates of dementia(all types), AD and YaD. However, risk factors for AD differed between these areas. In the urban sample, no education was the only significant factor ; whereas, aging and female gender were identified as risk factors in the rural sample. Conclusion : A high prevalence rate of dementia was observed among old persons in metropolitan Kwangju, consistent with previous studies conducted in other Korean areas. The risk factor profi1es for AD differed between urban and rural settings. The results of this study reflect the current status of dementia in Korea and suggests that appropriate management and prevention strategies for dementia should be tailored toward the geographic settings.