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      • 財閥企業과 非財閥企業간 技術革新에 관한 比較硏究

        신태곤,주수현 釜山大學校 商科大學 1994 釜山商大論集 Vol.65 No.-

        The purpose of this paper is to analyze empirically the difference of innovation between the Chaebol and Non-Chaebol in Korean manufacturing industries and suggest some policy implication for the purpose of promoting research and development on the basis of the empirical results. The classical Schumpeter's hypothesis states that there is a positive relationship between monopoly and degrees of innovation and that large firms are more innovative than small firms. Since then, however, empirical studies of the Schumpeterian hypothesis do not support this hypothesis. Instead, a new hypothesis has emerged : An effective oligopoly market (intermediate firms) promotes the highest rate of innovative activity. The empirical results are as follows: ① In linear regression analysis of R&D expenditure and firm size, R&D expenditure generally increases less than proportionately with firm size. In the two degree-polynominal relationship between R&D expenditure and firm size, it is found that the relationship has maximum point. Therefore, innovation is actively performed in the intermediate firms over large firms or small firms. In this case the Schumpeterian's hypothesis is unaccepted. ② The concentration of economic power in Korean economy is an important problem. Korean business groups are, in fact, controlled by a handful of owners in most cases. The relationship between group dummy variable and R&D intensity is a positive relationship. In LOGIT model estimation of group, a group is empirically explained with the diversity, ownership structure, etc. The impact of advertising intensity, growth of industry, capital/labors on R&D intensity is positive. The profitability, debt ratio is a negative relationship with R&D intensity. ③ This paper has examined the relationship between management stock holding and R&D expenditures of a firm respect to moral hazard and adverse selection in asymatric information. Agency theory implies that a manger is reluctant to take R&D expenditure. Management stockholding generally works to reduce agency problems between share holders and mangers. Empirical results show that R&D intensity rises as the increasing of management stock holding. In particular, it is found that the relationship has maximum point. The findings above suggest a valuable policy implication. The future R&D strategy have basically to strengthen the competition for innovation to maximize the profit resulting from it, and the policies to induce this circumstance must be enforced. Also, industrial innovation policy is needed to strengthen innovation by way of a harmonized promotion of both demand policy and supply policy.

      • KCI등재
      • 목초액의 엽면살포가 선학초(Agrimonia pilosa L.)의 종자수량에 미치는 영향

        정대수,신상현,김현경,오주성,이용호 東亞大學校 大學院 2002 大學院論文集 Vol.27 No.-

        Agrimonia pilosa L. has been used as a medicinal plant in traditional folk remedy, and it shows inereasing tendency at various sections such as medicine-making material, functional food, and agricultural chemicals using plant or extract. The treatment was 400times solution(50㎖), 600times solution(33.3㎖), 800times solution(25㎖), 1,000times solution(20㎖) and 1,200times solution(16.7㎖) level with foliar application of wood extraction in Agrimonia pilosa L. The results obtained through these experiments were summarized as follows; plant height, stem number, leaves was increased with 800times solution(25㎖) foliar application of wood extraction. Among foliar application of wood vinergar soution diluted by 800-1,200 times was most effective considering growth and yield as compared other dilutions and control plot.

      • KCI등재
      • 토끼 수막염 모델을 이용한 다제내성 폐렴구균에 대한 Meropenem의 치료 효과

        김신우,진정화,강수정,정숙인,김연숙,기현균,김춘관,이혁,김성민,백경란,송재훈 대한화학요법학회 2001 대한화학요법학회지 Vol.19 No.1

        목적 : 다제내성 폐렴구균에 의한 수막염은 기존과 단일 항생제로는 근치가 어려워 ceftriaxone과 vancomycin 혹은 rifampin의 병용요법이 권유되고 있다. 다제내성 폐렴구균에 사용할 수 있는 다른 약제 중 meropenem은 시험관내 폐렴구균에 대한 항균력이 좋고 경련 등의 중추신경계 부작용이 거의 없어 다제내성 폐렴구균에 의한 수막염의 치료에 이용할 수 있을 것으로 기대되나 이에 대한 자료가 매우 부족한 상태이다. 이에 연자 등은 meropenem과 meropenem+vancomycin의 병용요법이 다제내성 폐렴구균 수막염의 치료에 효과가 있는지를 토끼 수막염 동물 모델을 이용하여 검증하고자 하였다. 방법 : 인체에서 수막염을 일으킨 다제내성 폐렴구균 균주(penicillin MIC 2, ceftriaxone MIC 4, meropenem MIC 0.5㎍/㎖)를 토끼 척수강 내에 직접 주입하여 수막염을 유발한 후 ceftriaxone, vancomycin, rifampin, meropenem의 단일 항균요법, ceftriaxone+vancomycin, ceftriaxone+rifampin, meropenem+vancomycin의 병용요법 간에 치료 효과의 차이를 비교 하였다. 각 치료군은 6 마리의 토끼를 대상으로 하였다. 각각의 항생제는 5 시간 간격으로 2번 정주하였으며, ceftriaxone은 1회 투여하였다. 균주 주입 후 각 치료군이 토끼에서 치료 후 0, 5, 10, 24 시간에 척수액을 채취하여 균주의 수를 측정하여 24시간째의 살균 여부를 최종 치료 효과로 판정하였다. 결과 : meropenem 단독 요법은 10시간째에 모든 균주를 살균하였으나 24시간 째에 다시 균의 성장이 관찰되었으며, meropenem+vancomycin의 병용요법은 단독 약제보다 우수한 살균효과를 보였으나 상승작용은 없었다. 결론 : meropenem+vancomycin의 병용요법은 기존의 ceftriaxone+vancomycin보다 24시간째에 더 큰 균의 감소 경향을 보여(P=0.054) 임상에서 사용이 가능할 것으로 기대되며 향후 실제 수막염 환자에서의 임상효과를 증명하는 연구가 필요할 것으로 생각된다. Background : Because antimicrobial monotherapy for pneumococcal meningitis caused by penicillin-resistant strains is not satisfactory, ceftriaxone+vancomycin [C+V] or ceftriaxone+rifampin [C+R] regimens are recommended. Meropenern [M] is one of the monotherapy options for penicillin-resistant pneumococcal meningitis due to good in-vitro activity against pneumococci and rare adverse reactions in CNS. But there have been few reports in the efficacy of meropenern against pneumococcal meningitis. We evaluated therapeutic efficacy of the meropenern and meropenem+vancomycin in a rabbit model of meningitis caused by penicillin-resistant S. pneumoniae (PRSP). Methods : Meningitis was induced by intracistemal inoculation of a pneumococcal strain isolated from a patient with meningitis (MIC; penicillin 2, ceftriaxone 4, meropenem 0.5 g/㎖). Bacterial concentrations in the CSF were measured at 0, 5, 10, and 24 h after therapy was started. Therapeutic efficacy was evaluated by the final bacterial concentration in the CSF at 24 h. Results : C+V cleared the CSF at 10 h, but regrowth of bacteria was noted at 24 h. Meropenem monotherapy resulted in sterilization at 10 h but regrowth at 24 h. M+V was superior to M or V monotherapy but did not show synergism. Therapeutic efficacy of M+V was at least equal or superior to that of C+V (P = 0.054). Conclusion : Meropenem+vancomycin regimen could be one of the useful options in the treatment of PRSP meningitis. Clinical trials to evaluate the M or M +V are warranted in the future.

      • 인슐린의존형 당뇨병환자에서 임신중 병발한 당뇨병성 케톤산증 1예

        이성근,신영구,이성규,정윤석,이관우,김현만,김행수 아주대학교 1997 아주의학 Vol.2 No.2

        저자등은 인슐린의존형 당뇨병환자에서 임신중에 병발한 당뇨병성 케톤산증을 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. IDDM is an autoimmune disease resulted from beta cell destruction and insulin deficiency, and developed mostly in children and puberty. Ketoaddosis remains one of the most senous complications that can occur in the pregnant diabetic. A 26-year-old woman, gravida 1, para 0, was admitted at 32 weeks gestation because of fever lasted for 6 days. She had been treated with insulin pump during the pregnancy. Blood sugar was well controlled before admission, and the etiology of her ketoacidosis was urinary tract infection and no insulin-intake. DKA was treated with fluids and intravenous insulin. Urinary tract infection was treated with antibiotics, based on culture test. Healthy newbom was later delivered by cesarean section due to fetal distress. We experienced a case of DKA in pregnant woman and report it with a review on literature.

      • 무궁화 위성방송 수신용 고이득 마이크로스트립 배열안테나의 설계

        김진생,신현철,이문수 慶尙大學校生産技術硏究所 1996 生産技術硏究所論文集 Vol.12 No.-

        In this paper, a microstrip array antenna for receiving KOREASAT broadcasting is designed, which has left-handed circularly polarization property with the gain of 29dB at 11.84GHz. An antenna using a single feed point is chosen as an array element because of its simplicity and low feeding loss. The 2 X 2 array is a basic array element to achieve the overall 16 X 16 array antenna. All the elements of the array are fed in phase using the parallel feed method for broadside beam radiation. The actual dimension of array is about 30 X 30cm. The measured return loss and VSWR is in a good agreement with the calculations. The measured results are as follows ; SLL of -15dB below, gain of 27dB, directivity of 31.9dBi, and axial ratio of 0.74dB at 11.84GHz.

      • KCI등재

        폴리에틸렌 코팅 가스배관의 광범위탐상을 위한 유도초음파 모드 선정 및 결함 검출

        송성진,박준수,신현재 한국비파괴검사학회 2001 한국비파괴검사학회지 Vol.21 No.4

        폴리에틸렌 코팅 가스배관의 결함탐상을 위해 광범위 비파괴탐상기법인 유도초음파를 적용하였다. 가스배관의 내경은 190.7mm, 두께는 5.3mm, 그리고 바깥 표면은 1.9±0.5mm의 폴리에틸렌 층으로 코팅되어 있다. 폴리에틸렌 코팅 배관의 외면에 0.5MHz 탐촉자와 가변각 웨지를 사용하여, 비축대성 유도초음파를 가진 시겼다. 주파수와 위상속도 조정을 통하여 가스배관의 결함 탐상을 위한 적절한 모드를 찾아내고, 모드의 특성을 단시간 퓨리어 변환을 이용하여 분석하였다. 결함탐상 결과를 두께 손실 및 원통형 관통결함에 대한 인위결함에 대해 나타내었다. 그리고 가스배관에 인위적으로 삽입한 두께 손실과 원통형 관통결함에 대한 검출 성능을 평가하였다. Ultrasonic guided waves were explored to apply them to the long range inspection of polyethylene coated steel gas pipes. The steel pipes have such dimensions as 190.7mm inside diameter and 5.3mm thickness. The outside surface of the pipe is coated by a polyethylene layer of 1.9±0.5mm thickness. Non-axisymmetric guided waves were excited on the outside surface of the polyethylene coated pipe by using a 0.5 MHz transducer with a variable angle shoe. Frequency and phase velocity tuning was used to find optimum guided wave modes for the inspection. The dispersive characteristics of the modes were analyzed in time-frequency representation obtained by short time Fourier transforms. Sample results were presented for artificial defects such as wall thinning and hole.

      • KCI등재후보

        조선업 도장작업자의 유사노출군과 노출변이; 크실렌 노출을 중심으로

        고상백,노영만,임현우,신용철,김수근,최홍열,김재용,장성훈 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4

        목적 : 조선업 도장 작업자의 크실렌 노출을 평가하기 위하여, 수행직무 및 밀폐특성에 따라 유사노출군으로 구분하여 노출 변이 및 동질성을 파악하고자 하였다. 방법 : 3회 이상 반복측정이 이루어진 근로자 중동일공정에서 직무상 변동이 없는 근로자 총 28명을 대상으로 하였다. 노출농도 값을 대수전환(lOgtransformation)하여 근로자간, 근로자내 노출 분산요소을 추정하기 위하여, nested randomeffects ANOVA model을 활용하였다. 선정된 유사노출군 내 구성원의 측정 평균이 동일하다고 할수 있는지를 검정하기 위하여 분산요인(9f)을 산출하였고, 쿨즈0.031일 경우 동일하다고 생각하였다.또한 노출 값을 대수전환하여 95 %의 근로자(b-R9s)가 2배수 범위 내에 측정값을 가질 경우 동일하다고 생각하였다. bwRSS의 값을 유사노출군내의 근로자들간(between worker)의 기하표준편차(bwsy)를 구한 후 exp(3.92 bwsy)로 계산하여 산출하였고, 그 값이 2이하이면 동일하다고 생각하였다. 결과 : 일반적으로 유사노출군은 노출농도가 비슷한 것이라는 생각과는 달리, 직무에 근거한 유사노출군은 동질성 검정상 이질적이었다. 분무도장과 붓도장 모두 bwRss은 2를 초과하였고, 룰 또한 0.031를 초과하여 변이 폭이 컸다. 그러나 밀폐특성에 따른 노출 분포의 변이성은 직무만으로 구분했을 때의 변이지표 보다 그 수치가 낮아 밀폐특성으로 직무의 변이성을 설명 할 수 있었다. 결론 : 직무에 근거한 유사노출군이 동질적이지알다는 결과는 유사노출군으로 구분된 근로자의 업무특성이 하나의 유사노출군으로 설정할 수 없다는 점을 시사한다. 따라서 향후 작업환경 측정 시 직무뿐만 아니라 특정 업무(specific task) 또는 세부작업현황까지 파악할 필요성을 제시하고 있다. Objectives : This study was conducted to assess the concentration of xylene exposure and exposure variability of a similar exposure group (SEG) in accordance with job title and confined space. Method : The study subjects included 28 workers working in the painting process in the ship-building industry. Measurement of subjects were repeated three times. Within and between-worker exposure valiance components were estimated from log-transformed exposure concentrations employing a one-way nested random effects analysis of variance model. A uniformly exposed group was defined as one where the between-worker variance(σB2) was less than or equal to 0.031 or bwR95 ≤2, where bwR95 =exp(3.92 bwSy) , representing the radio of the mean exposures of the 97.5th and 2.5th percentile groups of the workers sampled. Result : The results indicated that, contrary to popular belief, similar exposed groups based on job title were heterogeneous. The between-worker variance(σB2) is large(≥0.031) and the ratios of the 97.5th and 2.5th percentile workers of the log normally distributed exposures of each group of worriers was more than 2. However dividing job title into confined space (in-block, out-block, in/out-block) decreased the between-worker exposure variability. Conclusion : This study focused on the quantitative aspects of exposure in painters in the ship-building industry. We cannot accept the assumption that SEG are uniformly exposed, as a major component of variation in exposure relates to differences in tacks or other factors. Therefore, the observational schemes can be improved by investigating Job-specific task and practice.

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