폐암에서 신생혈관형성과 Matrix Metalloproteinase-1, 2의 예후인자로서의 가치 평가에 관한 연구

이관우,조성진,김유훈,김영식,이대일 고려대학교 의과대학 1998 고려대 의대 잡지 Vol.35 No.3

Purpose : We investigated to determine whether angiogenesis and the expressions of metalloproteinase-1, and -2 could be useful as prognostic markers and therapeutic potentials in squamous cell carcinomas of the lung. Materials and Methods : We used immunohistochemical staining for factor Ⅷ, MMP-1 and MMP-2 from the paraffin-embedded tissues of 54 squamous cell carcinomas. The angiogenesis and expressions of metalloproteinase were analyzed by counting the number of tumoral vessels and immunohistochemically positive cells of MMP-1 and MMP-2, respectively. Results : Nodal metastasis group showed higher angiogenesis than that of non-metastasis one(p=0.008). As the clinical stage increases, angiogenesis was also increased. However, MMP-1 and MMP-2 expression with the presence or absence of lymph node metastasis and the clinical stages were not correlated, respectively. In addition, angiogenesis did not show any significant correlation with the expression rates of MMPs. Conclusion : We suggest that tumoral angiogenesis might provide informaton relevant to prognosis as well as treatment decisions, but not MMPs.

PⅡ-10 대체 배지자원을 활용한 봉지재배용 표고버섯 생산비 절감

이관우,김민자,주경남,전종옥,김익제 한국버섯학회 2018 버섯 Vol.22 No.1

PⅢ-5 수출 맞춤형 표고 완성형배지의 적품종 선발

이관우,전종옥,권영아,김익제 한국버섯학회 2018 버섯 Vol.22 No.2

The effect of endotracheal 1% lidocaine administration to reduce emergence phenomenon after general anesthesia

이관우,홍성만,지성미,이정국,권민아,박정헌,김석곤 대한마취통증의학회 2019 Anesthesia and pain medicine Vol.14 No.2

Background: Endotracheal intubation often causes sore throat and coughing. The aim of this study was to decrease the incidence and severity of cough, sore throat, and hemodynamic changes after extubation by endotracheal administration of 1% lidocaine. Methods: Sixty patients physical status American Society of Anesthesiologists classes I, II, and III who received a surgery under general anesthesia were randomly divided into two groups. L group was given 1% lidocaine 0.5 mg/kg by endotracheal administration. The other group, N group, received the same volume of normal saline. The number of cough, the severity of sore throat with numerical rating score (NRS), incidence of local anesthetic systemic toxic reaction, laryngospasm, and hoarseness were recorded. In addition, the number of coughs was divided into three levels by its severity, and it was converted into an indicator of cough score. Results: L group had a significantly lower number of cough and sore throat NRS (P value < 0.05) than the N group, and also hoarseness did not occur. The changes in the hemodynamic parameters, before and after the emergence of anesthesia, were more stable in the L group than those in the N group, but not statistically significant. Conclusions: The results of this study suggest that endotracheal administration of 1% lidocaine is effective and safe method to reduce cough and sore throat caused by extubation.

초전도 $Sr_2VO_3FeAs$에서 상관효과

이관우,Lee, K.W. 한국초전도학회 2010 Progress in superconductivity Vol.12 No.1

In the superconducting $Sr_2VO_3FeAs$, containing bimetallic layers, with maximum $T_c{\approx}\;46\;K$ correlation effects on V ions have been investigated using LDA+U method. Within the local density approximation (LDA) this system has the one-third filled $t_{2g}$ manifold of V, decomposed into $d_{xy}$ of bandwidth W=2 eV and nearly degenerate $d_{zx}d_{yz}$ of W=1 eV. Consideration of correlation effects leads to a metal-insulator transition on V ions $t^{2\uparrow}_{2g}\;{\rightarrow}\;d^{1\uparrow}_{xz}\;d^{1\uparrow}_{yz}$ at the critical on-site Coulomb repulsion $U_c$= 3.5 eV. At U=4 eV, the electronic structure, in which V ions are insulating, leads to several van Hove singularities near $E_F$ and similar Fermiology with other pnictides. Applying U to V ions results in increasing Fe moment as well as V moment, indicating somewhat hybridization between Fe and V ions even though this system is strongly 2-dimesional. Our results show possible importance of correlation effects on this system.

병재배 팽이버섯의 스마트팜 재배를 통한 생육환경 분석

이관우,전종옥,이경준,김영호,이찬중,장명준 한국버섯학회 2019 한국버섯학회지 Vol.17 No.4

In this study, smart farm technology was used by farmers cultivating 'CHIKUMASSHU T-011' in order to develop an optimal growth model for the precision cultivation of bottle-grown winter mushroom and the results of the same are mentioned herein. Farmers participating in the experiment used 60 m2 of bed area with 4 rows and 13 columns of shelf shape, 20 horsepower refrigerator, 100T of sandwich panel for insulation, 6 ultrasonic humidifiers, 12 kW of heating, and 20,000 bottles of Flammulina velutipes mushroom spores. The temperature, humidity, and carbon dioxide concentrations, which directly affect the growth of the mushroom, were collected and analyzed from the environmental sensors installed at the winter mushroom cultivation area. The initial temperature was found to be 14.5oC, which was maintained at 14oC to 15oC until the 10th day. In the restriction phase, the initial temperature was 4oC and was maintained between 2oC and 3oC until the 15th day, while during the growth phase, it was maintained between 7.5oC to 9.5oC. Analysis of the humidity data revealed initial humidity to be 100%, which varied between 88% to 98% during primordia formation period. The humidity remained between 77% to 96% until the 15th day, in the restriction phase and between 75% to 83% during the growth phase. The initial carbon dioxide concentration was 3,500 ppm and varied between 3,500 ppm to 6,000 ppm during primordia formation period and was maintained at 6,000 ppm until the 15th day. During the growth phase, the carbon dioxide concentration was found to be over 6,000 ppm. Fruiting body characteristics of 'CHIKUMASSHU T-011' cultivated in the farmhouse were as follows: Pileus diameter of 7.5 mm and thickness of 4.1 mm, stipe thickness of 3.3 mm, and length of 154.2 mm. The number of valid fruiting bodies was 1,048 unit per 1,400 mL bottle, and the individual weight was 0.71 g per unit. The yield of fruiting bodies was 402.8 g per 1,400 mL bottle.

路線分析方法과 그 適用(Ⅰ)

李觀雨,邊東健 淸州大學校 1977 論文集 Vol.10 No.1

전신마취하 제왕절개수술 40례에 있어서의 수술중 각성상태와 수술후 기억현상에 관한 연구

이관우 단국대학교 1997 論文集 Vol.31 No.-

Background: Wakefulness during Cesarean Section after anesthetic induction has been one of the well known issues of anethesiologists. In literatures, they said different induction agents might bring different results. The author intended to evaluate intraoperative wakefulness and postoperative recall at Dankook University Hospital. Methods: Forty pregnant women (ASA class Ⅰ or Ⅱ) at term who underwent general anesthesia for cesarean section received thiopental. 4㎎/㎏. A pressure tourniquet inflated to 250 ㎜Hg isolated her one arm from the effects of muscle relaxant so that wakefulness during anesthesia could be assessed by asking the patient to move her hand. To assess wakefulness, the patient was commanded to squeeze the investigator's hand a specified number of times. If the patient promptly squeezed the investigator's hand the appropriate number of times, the command was repeated but a different number of times specified. Only if the patient responded correctly both times, then we noted as a positive response. This test was repeated at 1 munute intervals beginning 1 minute after thiopental injection through the delivery. The tourniquet was deflated after the delivery. The author evaluated the postoperative recall by asking about the verbal commands'. Results: 1) Five of the forty patients responded o the verbal commands. 2) Twenty nine patients made the reaching movements. 3) The patients who had followed commands and the others did not have recall. Conclusions: The author concluded that the conservative general anesthetic method for Cesarean Section should be changed to lower the incidence of the intraoperative wakefulness.

理論의 性格과 理論形成을 위한 基本戰略

李觀雨 淸州大學校 1974 論文集 Vol.8 No.1

수출 맞춤형 표고 완성형배지 적정 규격 설정

이관우,전종옥,권영아,김영호,장명준 한국버섯학회 2019 버섯 Vol.23 No.2