복강경하 대장절제술을 시행 받는 환자에서 라모세트론과 온단세트론외 술 후 오심 및 구토 예방 효과 비교

김효중;어전영;어근무;어정한;엄세훈;조광래;김명훈 인제대학교 2011 仁濟醫學 Vol.32 No.-

Objectives : We evaluated the efficacy of ramosetron and ondansetron for preventing postoperative nausea and vomiting (PONV) in laparoscopic colectomy. Methods and Materials : Eighty patients who received laparoscopic colectomy were randomly divided into two groups: R group (ramosetron 0.1mg PO) and O group (ondansetron 4mg twice IV). Injection or oral medication was administered before the induction of anesthesia in each group. Injection was administered at the end of surgery in O group. General anesthesia was induced using propofol and rocuronium, and maintained with sevoflurane, remifentanil and air (FiO2 0.5), We investigated the incidences of PONV in each group by the Rhodes index of nausea, vomiting and retching (RINVR) at postoperative 6 and 24 hours. Results : The incidence of PONV was not different between group at each time points after surgery (at postoperative 6 hours: 20% in group R, 17.5% in group 0, at postoperative 24 hours; 12.5% in group R, 7.5% in group 0). There was no difference in the severity of PONV, satisfaction, rescue drug usage. Conclusion : Prophylactic therapy with ramosetron is as effective as conventional prophylactic therapy with ondansetron for preventing PONV in general anesthesia for laparoscopic colectomy.

관상동맥 시술 도중 발생한 좌주간부 관상동맥 박리에 대한 스텐트 삽입 치료의 단장기 임상 결과 : acute and long-term results

이세환,이승환,홍명기,김영학,이철환,한기훈,송종민,강덕현,송재관,김재중,박성욱,박승정 대한내과학회 2004 대한내과학회지 Vol.66 No.6

목적 : 심도자 사용 시술과 관련된 좌주간부 관상동맥박리에 대한 적절한 치료는 아직 확실히 정립되지 않은 상태이다. 이에 본 연구는 좌주간부 관상동맥 박리에 대한 스텐트 삽입술의 단장기 임상결과를 후향적으로 분석하였다. 방법 : 좌주간부 관상동맥 박리에 대한 치료로 즉각적인 스텐트 삽입술을 시행하는 것이 안전하고 효과적인 방법임을 가설하였고, 이러한 즉각적인 스텐트 삽입을 시행한 10명의 환자를 대상으로 단장기적 임상경과를 의무기록 고찰과 전화 면담을 통해서 평가하였다. 결과 : 전체 환자 모두 처음부터 좌주간부 관상동맥에 유의한 협착을 가진 환자는 없었으며, 8명의 환자는 심도자의 조작으로 인한 박리가 발생한 경우였고(진단적 혈관 조영술 중에 3명, 유도 도자 조작 중에 5명), 나머지 2명은 다른 병변에 스텐트 삽입시술을 하는 중에 박리가 발생하였다. 이 10명의 환자에서 모두 즉각적인 스텐트 삽입술이 시행되었고, 4명의 환자에서 시술 도중 혈압 저하로 Intra-aortic Ballon Pump (IABP)를 장착하였다. 모든 환자에서 성공적으로 스텐트가 삽입되었고, 병원내 사망은 1명도 없었다. 6개월 추적 관상동맥 조영술은 8명의 환자에서 시행되었다. 혈관 조영상의 재협착(직경 협착 50% 이상)은 8명 모두에게서 관찰되지 않았으며, 퇴원 후 평균 31±25개월의 추적관찰 결과 주요 심장사건은 1건도 발생하지 않았다. 결론 : 비록 대상 환자가 적은 연구였지만 좌주간부 관상동맥 박리에 대한 스텐트 삽입술은 기술적으로 안전하고 빠르게 시행 할 수 있으며, 훌륭한 단장기적인 치료 효과를 보여준다. Background : The optimal treatment of patients with left main coronary artery (LMCA) dissection during catheter-based procedure remains uncertain. We retrospectively analyzed the acute and long-term results of bail-out stenting for LMCA dissection. Methods : In cases with significant LMCA dissection occurring during catheter-based procedure, prompt stent implantation may be safe and associated with favorable clinical outcome. We evaluated the acute and long-term results of bail-out stenting for LMCA dissection occurring during catheter-bases procedure in 1- patients. Results : Initially, there was significant stenosis of LMCA segment in these patients. Catheter-induced dissection occurred in 8 patients (during diagnostic angiography in 3 patients and guiding catheter manipulation in 5 patients). Two patients suffered dissection in the setting of stent deployment in other vessels. Therefore, bail-out stenting LMCA dissection was performed in a total of 10 patients. In 4 patients, hypotension developed and intra-aortic balloon pump was placed during procedure. Stents were successfully deployed in all patients. There was no in-hospital mortality. Six-month angiographic follow-up was performed in 8 patients. Angiographic restenosis(diameter stenosis 50%) was not observed in all patients at follow-up study. During a mean follow-up of 31±25 months after hospital discharge, there was no major adverse cardiac event (death, myocardial infarction, and target lesion revascularization). Conclusion : Bail-out LMCA stenting is technically feasible, and showed good acute and long-term results in a small series of patients.

멸치젓의 呈味成分

李應昊,金世權,錢重均,金洙賢,金程均 釜山水産大學校 1982 釜山水産大學 硏究報告 Vol.22 No.1

멸치젓의 呈味成分에 관한 기초자료를 얻고자 생멸치와 이를 原料로 하여 제조된 멸치젓 중의 核酸關聯物質, 유리아미노산, betaine, TMAO, TMA 및 總creatinine을 分析하였다. 核酸關聯物質 중 생멸치에서는 IMP가 乾物量基準으로 2.8 μmole/g로 가장 많았으나 멸치젓에서는 hypoxanthine이 4.2 μmole/g으로 가장 많았고 , ATP는 흔적량에 불과 하였다. 멸치젓 중의 유리아미노산 중 함량이 많은 것은 leucine, isoleucine, phenylalanine, lysine, tyrosine, alanine, histidine, valine, methionine의 順이었고 glycine, proline, glutamic acid, arginine, threonine, serine 등은 함량이 적었다. 그리고 全유리아미노산은 젓갈 숙성중생원료에 비하여 약 2배로 增加 하였다. Betaine 은 생멸치 및 멸치젓 중에 各各 10.2㎎/100g, 30.0㎎/100/g였으며 이들이 엑스分室素에 대한 比率은 各各 0.6% 및 1.2%였다. TMAO 含量은 생멸치가 13.9㎎/100g, 멸치젓이 9.0㎎/100g였으며 TMA 含量은 各各 22.7㎎/100g 및 30.9㎎/100g였다. 總 creatinine 含量은 생멸치 및 멸치젓에서 各各 433.1㎎/100g, 575.8㎎/100g로서 엑스分室素에 대해 27.2% 및 22.8%였다. Omission test 結果 멸치젓의 呈味成分으로서는 유리아미노산 및 核酸關聯物質이 중요한 구실을 한다는 것을 알았다. This study was conducted to evaluate the taste compounds of fermented anchovy. The contents of such compounds as nucleotides and their related compounds, free amino acids, betaine, TMAO and total creatinine raw and fermented anchovy were analysed. The contents of IMP in raw anchovy appeared higher than other nucleotides and tended to decrease rapidly during fermentation. Therefore, in the case of fermented anchovy, hypoxanthine was abundant and IMP was very low in content. In the free amino acid composition of fresh samples abundant amino acids were leucine, isoleucine, phenylalanine, lysine, tyrosine, alanine, histidine, valine, methionine in order. Such amino acids as glycine, proline, glutamic acid, arginine, threonine and serine were poor in content. The contents of total free amino acids reached approximately about two times as compared with that of raw sample. The amount of betaine and TMA increased, while TMAO decreased during fermentation. The content of total creatinine in raw and fermented anchovy was occupied 22.8% and 27.2% of total of extractive nitrogen, respectively. As the results of omission test, the taste-active compounds of fermented anchovy are assumed to be free amino acids and nucleotides.

광대역 고출력 공간 전력 증폭 소자에 관한 연구

이성호,권세웅,이병무,윤영중 연세대학교 산업기술연구소 2002 논문집 Vol.33 No.2

In this paper, spatial amplifier using wideband printed dipole antennas is proposed for spatial power combining. The input and output printed dipole antennas have wide bandwidth of 22 %(5.44 ㎓∼6.75 ㎓) and 26.3 %(5.2 ㎓∼6.78 ㎓), respectively. Gain of the designed amplifier is 9.5 ㏈ at 6 ㎓. As a result, the proposed spatial amplifier using wideband printed dipole antennas and amplifiers shows that the gain is 16.8 ㏈ at 6 ㎓ and 3-㏈ gain bandwidth is 1.04 ㎓.

복합인식기를 이용한 무제약필기체 숫자인식

박중조,송영기,이세영 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

본 논문에서는 무제약 필기체 숫자의 인식을 위한 특징추출 방법과 인식기의 성능을 개선하기위한 인식기결합방법을 제시한다. 특징추출 방법은 영역분할특징, 교차특징, 그리고 방향특징으로 구성된다. 또한 단일 신경망을 이용했을 경우의 여러가지 문제점 즉, 수렴성, 계산의 복잡성 그리고, 정확성등을 개선하기 위한 방법으로 퍼지 적분을 이용하여 신경망을 결합하는 방법을 이용하였다. 캐나다 Concordia대학의 데이터를 이용하여 인식한 결과 97.7%의 인식률을 보였으며, 제시된 특징추출방법과 인식기의 결합이 좋은 성능을 지니고 있음을 보인다.

변이형 협심증 환자의 진단에 있어 Iodine-123Metaiodobenzylguanidine 심근 스캔의 유용성

하종원,이종두,장양수,정남식,권준,임세중,이영준,심원흠,조승연,김성순 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.2

성인에서 장기간 Furosemide오용과 연관된 신수질 석회화

김윤구,이윤하,이규백,장세호,김대중,오하영,김보현,김미경,조윤숙 대한신장학회 1996 대한신장학회잡지 Vol.15 No.4

乳牛에서 驅蟲效果가 泌乳量과 乳脂率에 미치는 效果에 관한 觀察

金泰鍾,李元暢,尹和重,金世寧 건국대학교 1995 學術誌 Vol.39 No.2

The purpose of this study was make an observation on effects of anthelmintics such as Albendazole, Ivomec-F and Nilzan for amount of milk production and milk fat levels before and after administration on Nematoda, Trematoda and Cestoda in helminths infestated from 218 heads of dairy cattle in Gyongi province. The results are summerizied as follows : Infestation and distribution rate in percent of helminths among the collected fecal samples from dairy cattle are Bunostomum species(spp.) 1.3%, Strongyloides spp. 4.5%, Tricostrongylus spp. 0.8%, Ostertagia spp. 7.3%, Cooperia spp. 4.7%, Nematodrius spp. 1.6%, Haemonchus spp. 5.7% and Oesphagostumum spp. 6.5% in Nematoda, and that of Eurytrema app. 2.1%, Fascioloa spp. 11.8% and Pharamphistomum spp. 51.3% in Trematoda, and that of Moniezia spp. in Cestoda, respectively. After administration for three kinds of anthelminthics infestated dairy cattle, high level of efficacy were confirmed against Nematodes and Cestodes. The average values tend to be incresed amount of milk production and its fat levels after anthelmintics administration on helminths infestated dairy cattle were 1.8 kg and 0.14 % per daily, respectively (p<0.01). Key word : Infestation of helminths in dairy cattle, Effects of milk products.

감염성 심내막염 환자에서 증상 없이 발견된 뇌동맥류 1예

김희만,임세중,이주용,이꽃실,김준명,홍유선,이규창 대한내과학회 2003 대한내과학회지 Vol.64 No.4

30세 남자 환자로 심내막염 진단 후 발견된 무증상의 감염성 뇌동맥류로 항생제 치료 후 단계적인 수술로 심장판막 대치술과 뇌동맥류 결찰술을 시행하여 심각한 뇌신경학적 후유증이나 합병증이 발생하기 전에 성공적으로 치료한 경험을 하였기에 문헌 고찰과 함께 보고하는 바이다. Cerebral mycotic aneurysm is an uncommon complication of infective endocarditis. In spite of low incidence, mycotic aneurysm is a serious complication because of the high risk of its rupture. Therefore, early diagnosis and management of cerebral mycotic aneurysm are imperative before the rupture. We experienced a case of asymptomatic cerebral mycotic aneurysm in a 30-year old man with infective endocarditis. He was admitted for splenic and renal infarction due to systemic embolization. The echocardiography showed severe mitral regurgitation, mitral valve prolapse and vegetation on the mitral valve. Streptococcus mitis was identified from blood cultures. In the course of antibiotics therapy, brain magnetic resonance image and 4-vessel cerebral angiography were performed, which revealed multiple unruptured cerebral mycotic aneurysms. Considering the high risk of rupture we performed mitral valve replacement with bioprosthesis. On follow-up cerebral angiography after the valve replacement surgery, one of aneurysms was enlarged, and successfully treated by surgical intervention without complication. We report one case of mycotic aneurysm without neurologic symptom in an infective endocarditis patient, who was treated without serious sequelae of the aneurysm. (Korean J Med 64:477-481, 2003)

가토의 골수내 식염수 주입이 말초혈액 제변수에 미치는 영향

황주일,김세경,이원재,이기중,김병기,박규남,김인철 大韓應急醫學會 1992 대한응급의학회지 Vol.3 No.1

Study Objective: To examine the effects of intraosseous saline infusion on hematologic parameters. Design and Setting: Eight New Zealand White rabbits were anesthized intramuscular ketamine injection, An initial blood sample was withdrawn from an earlobe artery under introduction of anesthesia. An 18-gauge intraosseous(10) needle was inserted into proximal tibia of rabbits, and 10 mL/kg of normal saline was infused over two minutes after the intraosseus needle insertion. Measurements: Complete blood counts were performed on the blood sampled. The light microscopic examination of the peripheral blood smear was perfomed by clinical pathologic staff. Results: No statistically significant differences were found in hematologic paramenters from samples drawn before and after intraosseous infusion. Conclusion: We advocate less caution in the interpretation of hematologic studies performed on blood samples obtained soon after an intraosseous infusion.