운동선수의 임장불안에 대한 연구

홍관이,이광재,김두경,부기원,노성규,한상준,박기동,오수일,문병용,이철규,박장평,엄기진,박남환 江原大學校附設 體育科學硏究所 1984 江原大學校附設體育科學硏究所論文集 Vol.- No.9

This study is designed to grasp the elements and situations of stage fright in order to propose a part of ways to cope with it. We make 511 top-class high school players, male and female, in the central districts (Seoul, Inchon, Kyungki, Chungbuk, and Kangweon Province) on object of questionnaire, and get the following results. Through players generally have all-round characters they show weakness in the superiority and emotional stability while showing strength in the sonformity. This fact comes to be related to the elements which cause stage fright. Physiological changes also have many effects on the symptom of stage fright. Especially, stage fright increases when players show sensitive reaction to the self-consciousness of final consequence which comes from the tension or uneasiness of sympathetic nerve, Thus, it turns out that players make use of reducing psychological burden by physical exercise or adjusting the level of demanded result in order to release the stage fright.

위암세포에 의한 종양침윤 림프구의 면역반응 억제기전에 관한 연구

박정규,송규상,서광선,최정목,배진선,장일성,윤완희,노승무,조은경,백태현 大韓免疫學會 1995 大韓免疫學會誌 Vol.17 No.3

Tumor-infiltrating lymphocytes ('1°ILs) interact most closely with tumor cells and thus are more likely to reflect tumor host interactions accurately. But it is unknown whether such T cells are nonspecific inflammatory cells or a subset of specific host immune responses. In this study, there was no clear correlation between the infiltration of T lymphocytes in stomach cancer and the overexpression of c-ErbB-2 or increasing class I MHC expression on tumor cells. A positive correlation was seen between the presence of TILs in the tumor and tumors with diploidy by flow cytometric DNA analysis. The proliferative responses of Ills stimulated with IL-2, anti-CD3 mAb, or both were examined. When compared to normal mucosal-associated lymphoid tissue lymphocytes, the proliferative response of TILs to high dose IL-2 was minimal. A similarly poor response to anti-CD3 mAb plus IL-2 was also observed. The freshly isolated TILs exhibit reduced ability to proliferate in response to IL-2, anti-CD3 mAb or both. The microenvironment of the tumor suppresses the proliferative capacity of the TILs. The mechanism of this suppression remains unknown. It could be mediated by suppressor cells, by soluble substances within the tumor, or both. To examine this question, supernatants of stomach cancer cells (SNSNU-1) were tested for the presence of immunosuppressive factors. Human peripheral blood T-cells and tumor-draining lymph node lymphocytes (TDLNL) were incubated for 3 days with SNSNU-1 and then assessed for proliferative responses to PMA, anti-CD28 mAb, or both and for the inducibility to express IFN- r or IL-4 mRNA to PMA. Peripheral blood T-cells pretreated with SNSNU-1 were unable to proliferate in response to PMA, anti-CD28 mAb or both. SNSNU-1 also produces inhibitory activities of TDLNL proliferative response to PMA or anti-CD28 mAb and PMA (49%, 52%, respectively). In contrast, culture supernatants obtained from HEp-2, K562 or Daudi showed normal proliferative responsiveness of peripheral blood T-cells and TDLNL by PMA, anti-CD28 mAb or both.

분석결과 검증 및 신뢰성 확보를 위한 실험실간 협력 실험

박혜진,고광용,한국탁,김일중,이용재,김성헌,이규승 충남대학교 농업과학연구소 2005 농업과학연구 Vol.32 No.2

The residual study of pesticide has been used in various areas, such as food safety, environmental protection, establishment of tolerance, and explaining the pathway and reaction mode of pesticides, and its importance was expected to increase further more. The aspect of food safety, the pesticide residue survey have been practiced at many organizations, but there were no verification of analytical results at present. In this experiment, we focused on instrumental stability, including response of each instrument and the recovery ratio of each organization's method. As samples for this experiment, we prepared cucumber and sesame, and chose 4 pesticides (bifenthrin, chlorpyrifos, diazinon, and ethoprophos), which were mostly detected from pesticide residue survey and widely used for each crop. The standard deviation of peak areas in the chromatogram of each pesticide were under 1.212 %, so it showed that most instruments were stable. The relationship of recovery ratio of each organization were over 0.996 for every pesticide and each organization. Finally, the analytical results for pesticide residue from each participated organization were not statically significant and we could put confidence in the result from each organization.

골격성 Ⅲ급 부정교합 환자에서 하악골상행지 시상분할골절절단술후 상순과 하순의 연조직 변화에 관한 연구

박관수,김태열,김희광,정정권,윤규호,전인성 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.6

Purpose : The prediction of profile change as a result of orthognathic surgery remains a problem during preoperative planning because of the difference relative movements of the hard and soft tissues. This study was performed to predict the changes o( upper and lower lips after BSSRO with non-rigid fixation Material and Methods : 15 patients wish skeletal Class III malocclusion treated by bilateral sagittal split ramus osteotomy(BSSRO) and mandibular setback were selected for analysis. Cephalometric data of presurgery and postsurgery 12 months were used. Wilcoxon signed rank test, calculation of Spearmans correlation rho and simple regression analysis were performed to predict the relations between hard tissue changes and soft tissue changes. Results : The horizontal change of hard tissue Pogonion and those of lower lips showed high correlation and the ratios were from 71% to 84%. The horizontal change of hard tissue Pogonion and those of chin showed high correlation and the ratios were from 90% to 92%. The horizontal change of hard tissue Pogonion and those of upper lips showed moderate correlation and the ratios were from 7% to 18%. Conclusion : This study suggests that the changes of lower lips are highly affected by the hard tissue change of mandible and those of upper lips are moderately affected. In comparison with other studies, no significant differences were found among the fixation methods.

좌심실 수축기 기능장애를 동반한 양수색전증 1예

박대균,홍경순,두영철,한규록,오동진,유규형,임종윤,고영박,이광학,이영,송원근,김현태 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.8

周易의 數槪念에 의한 景福宮 配置計劃에 關한 考察

朴光圭 광주대학교 산업기술연구소 1996 産業技術硏究 Vol.6 No.-

본 연구의 목적은 고대의 세계관과 철학 속에 나타나는 수의 개념이 건축물의 공간과 형태 구성에 어떠한 원리로서 작용하는가를 밝히는 데에 있다. 본 논문은 이 연구의 초기적 단계로서, 기 발표된 유사 연구의 내용에 대한 검토와 조선시대의 대표적 궁궐인 경복궁의 배치계획에 나타난 수개념의 상징성을 고찰하였다. 그 결과로서, 건축의 배치계획이 단순히 기능의 해결과 외견상의 형식미에 그치지 아니하고 당시의 세계관과 우주관등의 형이상학적인 개념의 표현이었다는 것을 엿볼 수 있다. 특히 수개념과 관련하여 경복궁의 배치계획에 나타난 상징성으로는 천문사상의 상징, 홍범구주의 상징, 문왕팔괘의 상징, 그리고 음양오행의 상징등에 대한 가능성을 찾을 수 있었다. This study was carried out to clarify how concept of numbers in the ancient view of world and philosophy acts on the composition of space and form in architecture, and what principle exists between them. As the first phase, literatures related were reviewed and the symbolism represented by the number concept at Kyungbok palace was investigated which is one of typical examples for the similar kinds in the Chosun Dyanasty.

결핵균 30 kDa 항원과 Triton X-100 Solubilized Protein 항원에 의한 대장암 주변 림프절 단핵구의 활성화

박정규,김광호,조은경,임재현,민들레,송영자,김화중,백태현 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1

Tumor-draining lymph node mononuclear (TDLMN) cells are specifically sensitized to the growing tumor but such cells are deficient for mediating an antitumor response. In this study, we examined the feasibility of using mycobacterial 30 kDa or Triton X-100 solubilized protein (TSP) antigen to stimulate mononuclear cells of colon cancer-draining lymph node for the generation of cell mediated immune effector cells. The proliferative response of TDLMN cells stimulated with mycobacterial 30 kDa or TSP antigen was determined by ^(3)H-thymidine incorporation assay. The proliferation of TDLMN cells to mycobacterial 30 kDa or TSP antigen was significantly increased in PPD (+) patients, but a poor response to the 30 kDa or TSP antigen was observed in PPD (-). The expression on γδ T cells to mycobacterial 30 kDa or TSP antigen was assessed by flow cytometry. The γδ T cells from PPD ( + ) patient responded only to 30 kDa antigen but to TSP antigen. An investigation of cytokine mRNA expression was undertaken using reverse transcription-polymerase chain reaction (RT-PCR) to follow TDLMN cells stimulated with the 30 kDa or TSP antigens for 5 days. The IFN-γ and TNF-α mRNA expression was only induced in TDLMN cells of PPD ( + ) patient in response to the 30 kDa or TSP antigen. The IL-2 mRNA expression was induced in both PPD (+) and PPD (-) in response to the 30 kDa or TSP antigen. But the IL-4 mRNA expression was not induced in response to the 30 kDa or TSP antigen. These results suggest that the 30 kDa and TSP antigens may serve as biologic response modifier for the generation of cell mediated immune effector cells.

24시간 혈청농도를 이용한 lithium 치료량 예측법의 평가

박언규,김광일 大韓神經精神醫學會 1981 신경정신의학 Vol.20 No.4

Lithium salt is a primary therapeutic and prophylactic agent for manic depressive disorder. But, safety range of the lithium salt is relatively narrow and the dosages to maintain optimum therapeutic serum level vary among individuals. By these reasons, it has been suggested that the application of lithium should start from low dosage and increase gradually by close observations of therapeutic effects and side reactions. This method, however, takes relatively longer period to reach the effective serum lithium level and manifests possible lithium toxicity. In 1973, Cooper and his colleagues reported the 24-hour serum lithium level as a prognosticator of dosage requirements for rapid and safe use of lithium salt. The authors attempted to evaluate the accuracy of this method as prognosticator of dosage requirements. Subjects of the study was 25 cases of manic depressive disorder. According to Cooper's method 600mg of lithium carbonate was administered orally to the patients and blood was sampled 24-hours later. The required dosages of lithium carbonate to reach therapeutic serum level (0.6∼1.2mEq/L) had been given orally and serum lithium levels were checked on the 7th and 14th days respectively after initial medication. The results are as follows: 1. Sensitivity of Cooper's method could be proved to be 0.80∼0.84. If th range of optimum serum lithium level is assumed to be 0.6∼1.5mEq/L, the sensitivity would be 0.96∼1.00. 2. After the Cooper's method, the 7th day serum checking seems to be sufficient to confirm therapeutic serum level. From the above results, the Cooper's method was proved to be useful prognosticator of dosage-requirement for rapid and safe lithium treatment.

근사적 전과정 평가 방법론 개발

박지형,서광규 한국전과정평가학회 2002 한국전과정평가학회지 Vol.4 No.1

본 논문에서는, 제품을 환경적 특징 (characteristic)에 따라 그룹핑하여 제품군을 형성하고, 제품군내의 제품 속성들로 환경영향 드라이버 (Environmental Impact Driver; EID) 인덱스(index)를 표현함으로써, 제품의 초기 설계 단계에서 사용할 수 있는 한가지 근사적 전과정 평가 방법론을 제안한다. 환경영향 드라이버 (Environmental Impact Driver; EID) 인덱스인 즉 하나의 환경 범주와 제품 속성들 사이의 상관 관계를 조사하여 통계적으로 관계를 검증한다. 개념설계 단계에서 그룹된 제품의 근사적 전과정 평가 결과를 예측하기 위하여 인공신경망 모델이 개발된다. 이 학습 모델은 각각의 환경영향 범주에 대해 관련 제품 특성들을 관련시킴으로써 일반화가 될 수 있다. 역전파(Backpropagation) 알고리즘을 갖는 인공신경망 모델이 사용되며, 그 결과는 중회귀분석의 결과와 비교된다. 제안된 방법은 완전 전과정평가 방법을 대체할 수는 없으나, 설계 개념 대안들에 대한 근사적 환경영향평가 결과를 제공해 준다. This paper proposes an approximate life cycle assessment (LCA) for the conceptual design stage by grouping products according to their environmental characteristics and by mapping product attributes into environmental impact driver (EID) index. The relationship is statistically verified by exploring the correlation between total impact indicator and impact category. Then an artificial neural network model is developed to predict results of approximate LCA of grouping products in conceptual design stage. The training is generalized by using identified product attributes for an EID in a group as well as another product attributes for another EIDs in other groups. The neural network model with back propagation algorithm is used and the results are compared with those of multiple regression analysis. The proposed approach does not replace the full LCA but it would give an approximate LCA results for design concepts.

慣習法上의 法定地上權

박규용,박광동 신라대학교 사회과학연구소 2003 사회과학연구 Vol.- No.6

I review some problems, the theory of making law, and the theory of legal Superficies on customary law. The problems are as follows. First it is easy to sacrifice an owner of the land because of too broad application of this law. Second, it is not perfect to make public notification about the real estate. Third, it is possible to give damage to the third person Fourth, it makes legal relationship complicated. In the theory of its interpretation, the need of Legal Superficies under customary law should be recognized, but the scope must be restricted strictly. And the opinion of persons concerned should be respected but the scope must be restricted strictly. And the opinion of persons concerned should be respected at first. In case of having Legal Superficies depending on the opinion of persons concerned, it is right not to allow Legal Superficies under customary law. (for example, buying and selling, donation) I review Legal Superficies in view of the theory of making law. ① Even though land and a building on it are separate estate, it is necessary to transfer it as one Properly. Finally, it is necessary to make law in order that the land and the building on it may be considered as one estate. ② In case that the owner of the land builds up a building on it, it is necessary to make law in order that the order of the land may set self-Superficies for himself for the good use of the land. ③ In summary, the point is that the theory of making law and the theory of Legal Superficies approach to the direction of the harmony of public interest and private interest.