용접공들의 면역능에 관한 연구

이수일,조봉수,김영욱,고광욱,조원근,김영실,강수용,황인경,조병만,김돈균 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.1

The authors examined human immunity indicators such as CD4, CD8, Natural Killer(NK) cell, IgG, IgA, and IgM, and heavy metals such as Pb, Cr, Cd to evaluate the health hazard of welders. We selected total 126 male subjects, 60 welders who had more than 5 year working history as an exposure group, and 66 office workers and medical college students as a control group. This immunity evaluation approach is the first newly designed study that has never been tried in past studies on welder's heath evaluation. And the results were as follows. 1. Total lymphocyte count of peripheral blood was significantly higher in welder group, 2,615±650 ea/㎕ compared with 2,368±681 ea/㎕ in control group(p>0.05). 2. The proportion of CD4, CD8, NK cell in welder group was 37.5±9.4%, 24.0±8.8%, and 21.0±9.5%, respectively, and 35.5±6.5%, 25.0±6.9%, and 19.6±8.8% in control group. CD4 and NK cell were slightly higher, and CD8 was slightly lower in welder group. but there was no statistical significance between two groups(p≥0.05). 3. IgG, IgA, and IgM in welder group were 15.9㎎/㎗, 2.7㎎/㎗ and 1.5㎎/㎗, respectively, and 15.6㎎/㎗, 2.9㎎/㎗ and 1.7㎎/㎗ in control group. There was no statistical significance between two groups(p≥0.05). 4. Blood lead, cadmium and chromium concentrations were 4.2±1.8㎍/㎗, 0.4±0.38㎍/㎗, 1.2±0.6㎍/㎗ in welder group and 3.2±1.7㎍/㎗, 0.44±0.29㎍/㎗, 1.1±0.6㎍/㎗ in control group, respectively, and these value were within normal ranges.

병원근무자에 대한 특수건강진단 적용 가능성에 관한 연구

이수일,조병만,조봉수,김영욱,고광욱,문남출,김주원 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.2

병원근무자들에 대한 특수건강진단 적용 여부를 판단하기 위한 기초자료를 제공하기 위해 1995년 3월 10일부터 4주간에 걸쳐 부산시내에 위치하는 2개 종합병원 근무자 830명을 대상으로 설문조사를 시행해 얻은 결과를 요약하면 다음과 같다. 1. 조사된 43개 항목 중 10% 이상의 대상자가 유해요인에 폭로되고 있다고 응답한 항목은 소음, 분진 등 16개 항목이었다. 이 중 분진, 소음 및 스트레스는 연구대상자의 50%이상에서 폭로되고 있다고 응답했으며 그 외 알콜류 소독제(41.3%), 방사선(34.6%), 일반약제(33.3%)의 순으로 폭로되고 있었고 VDT의 경우 25.2%, aldehyde류는 18.7%에서 폭로되고 있는 것으로 나타났다. 2. 대상자의 63.1%에서 병원근무 환경 중에 유해인자가 존재한다고 응답했고 병원의 환경측정이 필요하다고 대답한 사람은 80%에 달했다. 35.7%가 유해인자에 대한 교육을 받은 적이 없다고 응답했다. 전체 응답자의 35.7%가 유해인자에 폭로시 보호 장비를 착용하지 않는다고 응답했고 주기적인(격년) 건강진단은 48.6%에서 받는 것으로 조사되었다. 근무부서의 환기상태는 7.2%만이 좋은 편이라고 응답했다. 이상에서 살펴본 바와 같이 병원근무자들이 여러 가지 유해환경에 노출되고 있고 또, 이로 인해 발생할 수 있는 건강장해에 대한 예방대책이 소홀한 것으로 나타나 병원의 작업환경측정의 시행이 필요하고 이 결과를 바탕으로 병원근무자들에 대한 특수건강진단 적용여부를 결정해야 할 것이다. This study was performed to decide the possibility of special health examination to the hospital employees. We carried out questionnaire survey for 830 subjects at 2 general hospitals located in Pusan city. The summary of this study are as follows. 1. Above 10% of total hospital employees were replied that they exposed to 16 hazard items, such as dust, noise, stress and etc. Among them, over 50% of hospital employees exposed to dust(69.8%), noise(52.3%), stress(60.1%). And hospital employees exposed to alcoholic disinfectant(41.3%), radiation(34.6%), drug(33.3%), VDT(25.2%), and aldehyde(18.7%) also. 2. 63% of the hospital employees replied that there were hazardous factors in hospital environments, and 80% insisted the necessity for hospital environment measuring. 35.7% of respondents replied that they had never taken the education about hazardous factors. 35.7% of the total respondents answered that they didn't use protective equipment when exposed to hazardous factors. And 48.6% answered they took periodic health examination. Only 7.2% replied that ventilation condition of office room was proper. As shown in above results, hospital employees are exposed to various hazards, and turn out neglecting to health problems caused these hazardous factors. So at first, it is necessary to measuring hospital working environment, and then will be decided the possibility of special health examination to the hospital employees.

학교체육 활성화 방안에 대한 연구(Ⅰ) : 강원대학교 교양체육 운영방법의 개선을 중심으로

이광재,문병용,노성규,박기동,홍관이,한상준,유옥재,엄기진,정청자,오수일,김윤래,박장평,부기원 江原大學校附設 體育科學硏究所 1986 江原大學校附設體育科學硏究所論文集 Vol.- No.11

Try to find a scheme for activation to College Physical Education, this Report informs the various kinds of Survey and process those were projected for improvement of management methods on Cultural Physical Education in Kang Weon National University. From experimentally carried out "Sports events Choosing System" not as usual be inforced "Total practical Skill System", Following Positive effects and sujestions were Presented; 1. "Sports events choosing system" gave birth to more students' interesting and more voluntary participation to the sports events they chose, and sports skill and instruction level was elevated due to charge of expert according to each sports events. This system would be managed continuously hereafter for it related to life sports. 2. This System needs to closed cooperations between College and Community, for the facilities of community are utilized by college. 3. To complete the plan for activation of college Physical Education, additionally, the successional study ; namely "autonomous extracurricular sports activity" should be excuted hereafter.

核然料에 關한 硏究 : α-UO_3의 構造的 特性 Structural Characteristics of α-UO_3

李秀一,曺秉旭,洪光俊 조선대학교 기초과학연구소 1984 自然科學硏究 Vol.7 No.1

α-UO_3 have been prepared from uranyl acetate solution by the thermal decomposition method. The materials structure were examined by surface morpholgy, X-ray diffraction and optical density spectrum. The results showed that α-UO_3 exists two different crystalline forms depending on the temperature of precipitation ; hexagonl α-UO_3 at 350℃ and orthorhombic α-UO_3 at 600℃.

탄성 의치상 이장재의 캔디다 알비칸스 부착도에 관한 실험적 연구

하일수,조주온,이상돈,송광엽,박찬운 全北大學校 齒醫學硏究所 1992 전북치대논문집 Vol.10 No.1

The purpose of this study is to compare the response of four commercially available soft denture lining materials to the growth of C. albicans in vitro. Twelve samples of each soft lining materials were made to a uniform size and volume(15×5×4㎜) and sterilized using ethylene oxide. The samples were individually placed in culture tubes containing 5㎖ of sterile SDB(sabouraud dextrose broth dehydrated) and 0.1㎕ of activated C. albicans(ATCC 10231). The culture tubes had been incubated in incubator at 37℃. Three samples of each material had been tested at 3, 21, 35 and 56 days to determine the number of adherent cells of C. albicans on their surfaces and the number of nonadherent cells in the broth associated with each samples. The data have been analyzed by ANOVA and Scheffe test. The results have been obtained as follows : 1. In growth patterns of C. albicans within soft lining materials, Molloplast-B and K-33 were significantly higher(p<0.01) compared with Coe-Soft, but there was no significant difference between Coe-Soft, Coe Super-Soft and Mollosil(p>0.05). 2. Molloplast-B showed significantly higher(p<0.01) amounts of C. albicans adhering to its surface than other materials under experimental conditions. 3. Generally, adherence was significantly increased until 5 weeks, and after then showed decreased pattern in all materials(p<0.01). 4. The C. albicans was able to penetrate the inner portion of all samples. Coe-Soft showed most amounts of invaded C. albicans, followed in order by Mollosil, Molloplast-B, and Coe Super-Soft.

B형 간염 동반 원발성 간암 환자에서의 CYP2D6와 NAT2 다형현상에 관한 연구

신동일,이광수,최연남,황기은,조율희 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.2

The CYP2D6 and N-acetyltransferase (NAT2) are polymorphic enzymes which are expressed in the hepatocyte in a genotype-determined manner. CYP2D6 and NAT2 are known to be involved in the inactivation and activation of various mutagens and carcinogens, respectively. The activities of the two enzyme systems are associated with the genetic susceptibility of many human cancers. This study was performed to determine the genotype frequencies of the two enzyme systems in primary hepatocellular carcinoma patients and healthy controls. One hundred healthy controls and 55 liver cancer patients were analyzed by polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP). The results are as followings:1. In the healthy controls, CYP2D6 wild type allele frequency was 0.985 and CYP2D6^*4 frequency was 0.015, and no CYP2D6 poor-metabolizer was detected. No significant differences were found in hepatocellular carcinoma patient group. 2. Frequencies of F, S1, S2 and S3 alleles of NAT2 system were 0.725, 0.01, 0.14 and 0.125 in controls, respectively. The genotype frequencies were found to be 0.91 of rapid acetylator and 0.09 of slow acetylator. No significant differences were found in hepatocellular carcinoma patient group. 3. These results suggest that the distribution of CYP2D6 and NAT2 polymorphisms is very unique in Korean populations characterized by extremely low frequency of CYP2D6 poor-metabolizer and NAT2 slow acetylator. CYP2D6 and NAT2 polymorphisms seemed not to play an important role in the hepatic carcinogenesis in Korean population.

운동선수의 임장불안에 대한 연구

홍관이,이광재,김두경,부기원,노성규,한상준,박기동,오수일,문병용,이철규,박장평,엄기진,박남환 江原大學校附設 體育科學硏究所 1984 江原大學校附設體育科學硏究所論文集 Vol.- No.9

This study is designed to grasp the elements and situations of stage fright in order to propose a part of ways to cope with it. We make 511 top-class high school players, male and female, in the central districts (Seoul, Inchon, Kyungki, Chungbuk, and Kangweon Province) on object of questionnaire, and get the following results. Through players generally have all-round characters they show weakness in the superiority and emotional stability while showing strength in the sonformity. This fact comes to be related to the elements which cause stage fright. Physiological changes also have many effects on the symptom of stage fright. Especially, stage fright increases when players show sensitive reaction to the self-consciousness of final consequence which comes from the tension or uneasiness of sympathetic nerve, Thus, it turns out that players make use of reducing psychological burden by physical exercise or adjusting the level of demanded result in order to release the stage fright.

공기소총 사격시의 생체변화 분석

엄기진,이철규,박장평,이광재,문병용,홍관이,노성규,오수일,박기동 江原大學校附設體育科學硏究所 1985 江原大學校附設體育科學硏究所論文集 Vol.- No.10

This study conducted for analyze the process of physiological variation during shooting, and produce the basic data for training prescription to the performance improvement in Air Rifle Shooting, 9 Elite Rifle shooters )College 3, High School 3, Middle School 3) in GangWeon province were tested the physiological parameter which are Electrocardiograph(E.C.G), Heart-rate(H.R), Respiratory pattern, and Trigger time by polygraph system 8 channel from Sept. 1st to Sept. 10th, 1985. Analyzed experimental results are as follows; 1. Firing at T-P wave in E.C.G, 77.68bpm in H.R)16.68% by resulting H.R), the deep size of inspiration-expiration was low, and 8.34 sec of trigger interval were appeared when the shooter acquired high score. 2. The most effective factor among physiological parameters for excellent shooting score is the inspiratory volume with decresc breathing pattern. 3. Shooting performances correlated with stability and static-dynamic balance, but flexibility effected on negative correlation.

스테로이드 주사를 이용한 이개혈종의 치료

박재율,신승헌,김광훈,이웅렬,박일동,박광헌,마도훈,전일훈 대한이비인후과학회 2000 대한이비인후과학회지 두경부외과학 Vol.43 No.2

1988 년 가을 강원도 영서지역에서 발생한 쭈쭈가무시병 24 예의 임상적 관찰

최동성(Dong Seong Choi),이광훈(Kwang Hoon Lee),박진현(Jin Hyun Park),신계철(Gae Chul Shin),조한선(Han Sun Jo),심영학(Young Hak Shim),윤갑준(Gap Jun Yun),백일기(Ill Ki Baek),임채선(Chae Sun Im),호휘남(Whi Nam Ho) 대한내과학회 1989 대한내과학회지 Vol.37 No.3

N/A We obserbed 24 cases of tsutsugamushi disease occur- ring in the Gang-Won-Do area from September to October 1988, which were confirmed by indirect immunofluorescent antibody test, and analysed their clinical findings. On physical examination eschars which can be a clinical clue to tsutsugamushi disease in the early stage of infection were recorded in 11 cases (45%). Common laboratory features included thrombocytopenia in 19 cases (95/o), and increased SGOT in 22 cases (92%), SGPT in 49 cases (79%), LDH in 19 out of 20 cases (95%) tested, CK in 7 out of 20 cases (35%) tested and serum ADA level in 12 of 13 cases (92%) tested. Serum fibrinogen was decreased in 5 of 13 cases (38%) tested, FDP was positive in 8 of 13 cases (62%) tested and prolonged prothrombin time was observed in 9 cases (38%). When IgM and IgG titers were measured separately, two distinct responses were seen. The IgM titers gradually declined during the period from 14-40 days. The IgG responses in the same patients developed more slowly. In our study, tsutsugamushi disease was a mild to severe febrile illness of 1 to 2 weeks duration. We think that more concern about tsutsugamushi disease is necessary because of possible mortality in poorly treated cases as well as a need for more precise differential diagnosis of acute febrile illness.