수종 상아질 표면처리제가 5급 와동 충전시 치은측 변연누출에 미치는 영향에 관한 연구

이현희,박금순,손호현 全北大學校 齒醫學硏究所 1990 전북치대논문집 Vol.8 No.1

The purpose of this study was to evaluate the effect of various Dentin Conditioners on the gingival marginal leakage of Class Ⅴ cavity. V-shape cavities were prepared on the faciocervical area of 55 extracted human premolar or molar teeth. Gingival margin of cavities was placed on cementum. They divided into 5 groups according to dentin surface treatments as follows. The exposed dentinal surfaces were treated with 3% H_2O_3, Cavity Cleanser(Columbus/Bayer), Dentin Conditioner(GC Inter. Co.) and Scotchprep(3M Co.) in 4 groups respectively and were not treated in 1 group as control. After dentin treatment, Dentin Adhesive(3M Co.) was applied on the treated dentin surface and Silux(3M Co.) was filled and polished. Dye penetration technique using 50% silver nitrate soultion was adopted to assess gingival marginal leakage. The following results were obtained. 1. Dye penetration degree was the least in the cavities treated with Scotchprep, and were increased in the order of Dentin Conditioner, Cavity Cleanser and 3% H_2O_2. 2. Gingival marginal leakage was significantly less in the Scotchprep treated group compared with non-treated group(p<0.01). 3. Gingival marginal leakage in the groups treated with Scotchprep^**, Dentin Conditioner^**, Cavity Cleanser^* were less than in the group treated with 3% H_2O_2(** : p<0.01, * : p<0.05). 4. Gingival marginal leakage among the groups treated with Scotchprep, Dentin Conditioner and Cavity Cleanser was not different(p>0.05). 5. The degree of gingival marginal leakage in the 3% H_2O_2 treated group was greater than in the non-treated group, but was not stastically significant(p>0.05).

개구리 皮膚의 Na 輸送에 關與하는 Dopamine係

李俊禮,崔峰奎 全北大學校 齒醫學硏究所 1988 전북치대논문집 Vol.6 No.1

To ascertain the existence of dopaminergic receptors involved in active transport of sodium in the frog skin and to delineate the physiological role, the effects of dopamine (DA), apomorphine (Apo) and bromocryptine (BRC) on the potential difference (PD), short-circuit current (SCC) and total skin conductance (TSC) of the isolated frog skin, as well as the influences of dopaminergic and alpha-adrenergic blockers upon the effects of dopaminergic agonists were studied in Rana nigromaculata. PD and SCC were determined by utilizing the Ussing technique. Both sides of the isolated frog skin were perfused with Ringer solution for cold-blooded animal. All the drugs were applied to the serosal side of the skin. Results were summarized as follows : 1. The responses to DA(6.5×10^-6 - 2.0×10^-4M), Apo(3.74×10^-6 - 3.74×10^-4M), and BRC(1.53×10^-6 - 4.60×10^-5M) were characterized by elevation of PD and SCC roughly in a dose-related fashion, but the maximal effects attained by DA were greater than those of Apo and BRC. Both Apo and BRC induced graeater increases in PD than SCC, resulting in slight decrease of TSC, whereas no change in TSC was noted with DA. 2. These increments of PD and SCC were inhibited by dopaminergic blockers, such as haloperidol (8.0×10^-5M), metoclopramide (1.0×10^-4M) and sulpiride (8.8×10^-5M). 3. The stimulatory effects of dopamine on PD and SCC were significantly inhibited also by prazosin (2.6×10^-6M), a specific alpha-1 adrenoceptor blocker and were completely abolished by phenoxybenzamine (3.3×10^-6M), an irreversible alpha-adrenoceptor blocking agent. 4. Norepinephrine (6×10^-8 -6×10^-5M), produced increases in PD and SCC. However, these effects were inhibited by prazosin but not influenced by sulpiride pretreatment. These results suggest that the dopaminergic system may play a role in the control of sodium transport in the frog skin, and that alpha-adrenoceptors may also be involved in the dopamine-induced increase of sodium transport. However, based on evidence at hand, no conclusion could be drawn on the subtypes of dopamine receptors mediating in the stimulation of sodium transport in the frog skin.

치은출혈과 전신인자 사이의 상관성

채규삼,신금백,안낙현 全北大學校 齒醫學硏究所 1991 전북치대논문집 Vol.9 No.1

In order to evaluate the possible contributing systemic factors to the gingival bleeding as an important determinant, clinically, in diagnosis and prognosis of periodontal disease, the author probed papillary gingival crevices by modified Ramfjord's method and calculated the gingival bleeding indices in 564 male and 198 female ranged from 21 to 65 year-old age visited Chonbuk National University Hospital to check their health states. And the author analyzed the correlation between the gingival bleeding index and the possible contributing systemic factors-blood pressure(systolic, diastolic), total cholesterol, fasting blood sugar, serum glutamic oxalacetic transaminase(SGOT), serum glutamic pyruvic transaminase(SGPT). The results were as follows : 1. The mean values of gingival bleeding index per probed tooth according to subjects grouped by age were 0.33±0.46 in 20s, 0.29±0.42 in 30s, 0.34±0.50 in 40s, 0.39±0.47 in 50s, and 0.26±0.27 in 60s. 2. The mean values of gingval bleeding index per probed tooth according to positional group of probed teeth were 0.33±0.70 in maxillary group, 0.32±0.70 in mandibular group, 0.32±0.72 in anterior group, and 0.33±0.69 in posterior group. 3. The estimated mean values of possible contributing systemic factors to gingival bleeding from total subjects were 119.0±10.9㎜Hg in systolic, blood pressure, 79.4±9.0㎜Hg in diastolic blood pressure, 189.8±36.7㎎/㎗ in total cholesterol, 89.3±18.8㎎/㎗ in fasting blood sugar, 30.6±14.7 U in SGOT and 27.2±14.7 U in SGPT. And the correlation between systolic blood pressure and diastolic blood pressure was highly significant(r=0.71), and also the correlation between SGOT and SGPT was highly significant(r=0.65). 4. In general the mean values of gingival bleeding index of total probed teeth per subject were higher in groups of subjects with fasting blood sugar above 140㎎/㎗, 180㎎/㎗, with SGOT above 50U, and with SGPT above 45U than in groups of subjects with levels of preceding systemic factors below preceding values of parameters.

구강외과 수술전후의 尿中 17-OHCS, free cortisol 변화에 관한 임상적 연구

이희원,박승오,김오환 全北大學校 齒醫學硏究所 1988 전북치대논문집 Vol.6 No.1

Activation of the pituitary-adrenocortical system normally occurs in response to a variety of alterations in the environment of the organism. The author attempted to investigate the relationship between physiologic response and stress during operation of oral & maxillofacial surgery. The results were revealed as follows : 1) The amount of urinary 17-OHCS was increased at operation day, under 30 years old patients, untraumatized patient, large operation. 2) The amount of urinary free cortisol was increased at operation day, anxiety group patients and small operation.

만성 치근단주위 병소조직의 Arachidonic acid 대사에 관한 연구

박금순 全北大學校 齒醫學硏究所 1991 전북치대논문집 Vol.9 No.1

This study was executed to measure the biosynthesis of arachidonic acid metabolic products in chronic periapical lesions, to compare the products among periapical granuloma, periapical cyst and chronic periapical abscess, and to understand the pathogensis of chronic periapical lesions. Tissues from 33 chronic periapical lesions of human teeth were enucleated during endodontic surgery. Large part of each tissue was contained in liquid nitrogen immediately and the other was examined histologically. In histologically diagnosed 8 cases of periapical granuloma, 9 cases of periapical cyst and 8 cases of chronic periapical adscess, the tissues were homogenated and incubated with ^14C-arachidonic acid. Lipid solvent extracts were separated by thin layer chromatography to be analyzed by autoradiography and TLC analyzer. 1. TXB_2, 6-keto-PGF_1α and PGE_2, LTB_4, HETEs, and unidentified product which are metabolic products of arachidonic acid were measured in the tissues of chronic peripaical lesions. 2. In all of periapical granuloma, cyst and abscess, the conversion rate of HETEs among all products was the highest(P<0.05), and the percentage of HETEs in total converted products was also the highest (P<0.05). 3. The concentration of each arachidonic acid product was higher in chronic periapical abscess than in periapical granuloma and cyst(P<0.05). The concentration of TXB_2 and HETEs in periapical cyst were higher than that in periapical granuloma. 4. The relative amounts of total products from lipoxygenase pathway to those from cyclo-oxygenase pathway were about 7 fold in chronic periapical lesions. There was no difference among periapical granuloma, cyst and abscess(P>0.05). The total amount of products from each pathway were higher in chronic periapical abscess than in perapical cyst and granuloma.

산부식전 소와 열구 처리법에 따른 치면 열구 전색재의 변연 봉쇄성에 관한 연구

安帥炫,金秀也,白秉周 全北大學校 齒醫學硏究所 1993 전북치대논문집 Vol.11 No.1

The purpose of this study was to evaluate the marginal sealing of pit & fissure sealant according to the treatment of pit & fissure prior to acid etching in permanent premolar & molar. 20 premolars & 30 molars were used for experiment. They were classified into 5 experimental group at random : Group 1 was not treatment and Group 2, 3, 4, 5 were respectively treatment with pumice, small round steel bur of low speed handpiece, pointed diamond bur of high speed handpiece, Murakami R.I. No. 1-2. All the specimens were then thermocycled in a range of 4℃∼54℃ and immersed in 2% methylene blue dye solution for 24 hours and sectioned with low speed diamond cutter into two part under water condition. All the specimens were observed at pit & fissure-sealant interface with light microscope & statistical analysis was performed. The obtained results were as follows ; 1. There were significant increase in marginal sealing of high speed handipiece-pointed diamond bur group in contrast to pumice group at significant level α=0.05 when compared by dye penetration score(P<0.05). 2. There were significant increase in marginal sealing of low speed handpiece-small round steel bur group, high speed handpiece-pointed diamond bur group and Murakami R.I. No 1-2 group in contrast to pumice group at significant level α=0.01 when compared by dye penetration score(p<0.01.) 3. There were significant increase in marginal sealing of low speed handpiece-small round steel bur group, high speed handpiece pointed diamond bur group and Murakami R.I. No. 1-2 group in contrast to pumice bur group and Murakami R.I. No. 1-2 group in contrast to pumice group at significant level α=0.01 when compared by dye penetration length(p<0.01). 4. When compared by dye penetration score, it is lowest in high speed handpiece-pointed diamond bur group and lower in low speed handpiece-small round steel bur group, Murakami R.I. No. 1-2 group, pumice group, no treatment group in sequence. 5. There were better penetration force of pit and fissure sealant in low speed handpiece-small round steel bur group and high speed hdndpiece-pointed diamond bur group than no treatment group, pumice group and Murakami R.I. No. 1-2 group.

치과용 레진 시멘트의 피막도에 관한 실험적 연구

조국현,송창용,송광엽,박찬운 全北大學校 齒醫學硏究所 1993 전북치대논문집 Vol.11 No.1

The purpose of this study was to evaluate and compare film thickness of five kinds of resin luting cements [Comspan, Panavia Ex, Maryland bridge adhesive, All-bond C & B cementation kit, and Super-bond C & B]. Zinc-phosphate cement and glass-ionomer cement were used as the control group. In order to measure the film thickness, the methods used were in broad compliance with ADA Specification No.8, a tapered-die system that simulates clinical conditions more closely, and the connected tapered-die system that simulates bridge conditions. The inorganic filler size of resin cements was also examined with scanning electron micrographs. The results were obtained as follows ; 1. The film thickness of resin cements was increased in the order of Comspan, Panavia Ex, Super-bond C & B, Maryland bridge adhesive, and All-bond C & B cementation kit. Maryland bridge adhesive and All-bond C & B cementation kit showed significantly higher film thickness than the control group(p<0.01). 2. For all resin cements, there was a significant difference of film thickness between the ADA method and the tapered-die system. Generally, the tapered-die system demonstrated lower film thickness than the ADA method(p<0.01). 3. There was no significant difference in film thickness between the tapered-die system and the tapered-die bridge system in all resin cements(p<0.01). 4. The scanning etectron microscope showed that the cement with larger filer had a tendency to be higher in film thickness.

MEAW가 야기하는 응력 분포에 대한 광탄성학적 연구

이승호,김정기,김오환 全北大學校 齒醫學硏究所 1993 전북치대논문집 Vol.11 No.1

This study was designed to investigate the stress distribution, intensity and force mechanism derived from MEAW by photoelastic stress analysis of the artificial teeth and surrounding bone composed of photoelastic material(PL-3). The findings of this study were as follows ; 1. On the MEAW with tip back, the stress was observed between the lower lateral incisor and lower canine greatly and on the lower first, second molar lightly. Upper molar were observed moderate stress, the light stress was observed on the anterior teeth area. Upper and lower premolar were not observed the stress or light stress. 2. In case of the vertical elastics on the MEAW with tip back, the great stress on the upper and lower lateral incisor were extrusion and the moderate stress on lower second molar was evident that tip back effects were increased and the stress was increased by extrusion on upper incisors. 3. In case of the CⅡ elastics on Plain arch wire, the stress was concentrated on the area hanged by elastic but in case of the CⅡ elastics on MEAW, the stress was transmittded to the posterior teeth area on the upper jaw, to the anterior teeth area on the lowerr jaw. On MEAW with tip back, tip back effects was more increased by the CⅡ elastics and the stress was greatly. 4. In case of the CⅢ elastics on MEAW with tip back, the great stress was observed on the upper anterior teeth and posterior teeth by tip back effects, and on the lower anteroir teeth.

하악매복지치 발거시 혈당변동에 관한 임상적 연구

양상일,박경정,진우정,신효근 全北大學校 齒醫學硏究所 1988 전북치대논문집 Vol.6 No.1

Thirty three healthy adult patients who needed extraction of impacted lower third molar were studied. We focused on the changes of blood glucose and autonomic nervous system during surgical extraction and additionally the psychologic factor using DAS-J was checked to find the relationship with this study. This study was divided into before operation, immediatly before operation and immediatly after operation. The obtained results were as follows : 1. Blood pressure was increased immediatly after operation but not significant. Pulse rate was more increased in immediatly after operation than before operation(p<0.05). 2. Blood glucose was more increased in immediatly before operation than in before operation(p<0.05), and it was highly significant in immediatly operation(p<0.01). 3. The degree of surgical trauma (operation site, amount of local anesthetics and operation time) was not influenced of the changes of blood glucose.. 4. The changes of blood glucose and autonomic nervous system were not related to the psychologic factor measured by DAS-J.

성견 치주질환시 치은열구액 내의 Arylsulfatase에 관한 실험적 연구

이인규,김형섭 全北大學校 齒醫學硏究所 1988 전북치대논문집 Vol.6 No.1

It is diagnostically interesting to measure the enzyme activity as an indicator of the patient's present state of periodontal disease. In addition, it is also useful to consider the relationship between enzyme activity and clinical index. The arylsulfatase activity was measured and compared with volume of gingival crevicular fluid and clinical index. The purpose of this study was to reveal the diagnostic value of the enzyme. Experimental periodontitis was induced by ligating the left third and forth premolars of maxilla and mandible with wire from 4 dogs of 13∼15㎏. Contralateral teeth were brushed 3 times a week as the control site. In two months, tile filter paper strip was inserted into the gingival sulcus of the same teeth and gingival crevicular fluid was collected. After that, Periotron units and arylsulfatase activity were measured ; sulcus bleeding index, plaque index, pocket depth were also measured. 1. Average values of arylsulfatase activity (optical density) were 0.043±0.014 and 0.021±0.006 at the experimental and control areas, respectively. 2. The relationship of periodontal clinical indices and Periotron units was statistically significant when the experimental and control areas were compared(p(0.01) .(p<0.01). 3. Correlation between arylsulfatase activity and Periotron units was statistically significant(p<0.01). 4. As the degree of sulcus bleeding index and the pocket depth increased, Periotron units and enzyme activity also increased.