부산·울산·경남지역 직업병 감시체계

김정일,김병권,김정원,채창호,이철호,강동묵,김지홍,김진하,김영욱,이영하,이지호,김정호,윤형렬,유철인,정백근,장태원,김운규,윤동영,강진욱,김종은,안진홍,이동준,장준호,이광영,송혜란,최영희,이용환,조병만,최홍렬,고상백,김은아,이유진,홍영습,정갑열,김정만,김준연 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.1

Objective: Occupational medicine specialists in the Busan, Ulsan and Kyung-Nam areas established an area-based occupational disease surveillance system and used this system to collected case information for the purpose of preventing occupational diseases Methods: l l hospital participated in this system. The authors selected five main diseases, which were hand-arm vibration syndrome (HAVS), work-related musculoskeletal disorder (WRMSD), occupational asthma, occupational skin disease and occupational and occupational lung cancer and established their case definitions. All cases were reported on the web, and real time analysis was conducted. Results: Between April 2001 and April 2003, 192 cases of HAVS, 118 cases of WRMSD, 33 cases of occupational asthma, 17 cases of occupational skin disease and 17 cases of occupational lung cancer (for a total of 377 cases of these five main diseases) were reported. most of the HAVS cases came from shipbuilding, and 172 of them (92.7%) were associated with grinding. Of the four main types of WRMSD, carpal tunnel syndrome (CTS) was the most prevalent with 46 cases and shipbuilding was also the main industry involved (83.9%). The ergonomic risk factors involved mainly associated with the hand. In 19 (57.6%) and 4 (12.1%) cases of occupational asthma, the agents involved. The causative agents of occupational lung cancer included Cr, welding fume, PAH, Ni, etc. 10(58.8%) of the cases were diagnosed as squamous cell carcinoma and 5(29.4%) as adenoma. Conclusion: This result showed that an area-based occupational disease surveillance system might provide an effective method of evaluating the prevalence of such diseases, however the Busan, Ulsan and Kyung-Nam provinces are too large to be treated as individual areas. Therefore, the authors suggest that each province should establish its own surveillance system.

인천지역 TDI 노출 작업자에서 직업성천식 유병율

김형렬,김철우,홍윤철,전형준,김치년,김현수,이지나,신주연,고동희,노재훈 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.2

목적 : TDI는 직업성천식을 일으키는 대표적인 물질로 알려져 있다. 과거 TDI에 노출된 작업자들의 천식 발생률을 5~6%가량 보고하였고, 국내에서도 2-20%에 이르는 유병율을 보고한바 있다. 작업환경이 많이 개선되고, 노출량이 감소된 최근에도 TDI에 의한 직업성천식에 대한 보고가 많이 이루어지고 있어, 이에 대한 적극적인 조사와 진단과정을 통해 유병율을 구하고 질병발생의 변화양상을 파악해 보고자 하였다. 방법 : 인천지역에서 특수건강진단을 수행하는 2개 기관의 TDI 노출 근로자 400여명 중, 사업장의 규모가 50인 이상이며 사업주가 연구진행을 허락한 사업장에서 근무하는 근로자 중 직접적으로 TDI에 노출되는 작업에 종사하는 근로자 170명을 연구대상으로 하였다. 이들에 대해 설문지와 산업의학의사의 면담을 통한 작업관련성 평가를 근거로 정밀대상자를 선정하고 이들에 대해 메타콜린 유발시험, TDI 유발시험 등을 수행하여 직업성천식을 확인하였다. 결과 : 설문조사 결과 11명이 직업과 관련하여 천식증상을 보이는 것으로 나타났고(6.9%), 이중 7명에서 메타콜린 유발검사 양성소견을 보였다. TDI에 의한 특이유발시험 결과 1명에서 양성반응이 나타나, 이 집단에서 TDI에 의한 직업성천식의 유병율은 0.58%였다. 결론 : 과거 국내연구에서 TDI에 의한 직업성천식의 유병율이 2~20%에 이르렀던 데 비해, 본 연구에서는 0.58%로 나타났다. 이는 국외 논문에서도 나타나는 경향으로 작업장 노출량 감소로 점차 발생률이 감소하는 양상을 보이고 있다. 그러나 이미 증상이 나타난 근로자들이 부서를 옮기거나, 직장을 그만둠으로 인해 그 유병율이 과소평가되었을 가능성도 있다고 판단된다. Objecdives: This study was carried out to estimate the prevalence of isocyanate-induced occupational asthma in toluene diisocyanate (TDI) exposed workers. Methods: We examined 170 workers who had been directly exposed to TDI through a medical questionnaire, physical examination, and pulmonary function test. Based on screening examination, workers with suspected occupational asthma were selected for further evaluation such as methacholine and TDI challenge tests. Results: Eleven (6.9%) among 170 workers complained of symptoms of occupational asthma. and 7 among these 11 symptomatic workers showed positive responses to the methacholine challenge test (4.1 %). One spray painter was confirmed as having the TDI induced occupational asthma following a positive response to TDI challenge test. Conclusions: The prevalence of TDI-induced asthma was at 0.58% was lower than that for former studies (2-20%). Improved workplace environment, lower level of TDI exposure compared to the past, and the healthy workers effect may have contributed to this low rate of asthma prevalence in workers with TDI exposure.

Breeding of Tetraploid in Codonopsis lanceolata (Sieb. et Zucc.) Trautvetter by Colchicine Treatment

Kim,Ik-Hwan,Kim,Hag-Hyun,Hong,Eui-Yon,Yun,Jong-Sun,Yun,Tae,Hwang,Ju-Kwang,Lee,Cheol-Hee 한국자원식물학회 2003 Plant Resources Vol.6 No.3

Present studies were carried out to produce tetraploid plants by colchicine treatment using seeds, seedlings and shoot tips of Codonopsis lanceolata. Three tetraploid plants of C. lanceolata were produced from seeds which absorbed 0.1 % colchicine solution for 12 hours, and 0.5% colchicine solution for 1 and 6 hours from seedlings, respectively. But tetraploid was not produced from shoot tips treated by colchicine solution. Compared to diploid, tetraploid plants had larger stomata, but less number of stomata. Fresh weight of tetraploid plants was 1.4∼3.6 times heavier than diploid plants.

Breeding of Tetraploid in Platycodon grandiflorum (Jacq.)A. DC. by Colchicine treatment

Kim,Ik-Hwan,Kim,Hag-Hyun,Hong,Eui-Yon,Yun,Jong-Sun,Yun,Tae,Hwang,Ju-Kwang,Lee,Cheol-Hee 한국자원식물학회 2003 Plant Resources Vol.6 No.3

Present studies were carried out to produce tetraploid plants by colchicine treatment using seeds, seedlings and shoot tips of Platycodon grandiflorum in Campanulaceae. The most successful colchicine treatment for tetraploid production in P. grandiflorum was soaking treatment using 0.01 and 0.5% colchicine solution for 1 hour and 12 hours, respectively. Morphological characteristics of both diploid and tetraploid were similar, but tetraploid plants had more leaves. Compared to diploid, tetraploid had the larger stomata, but less number of stomata. Fresh weight of tetraploids was 20∼40% heavier than that of diploid.

고령 두부외상 환자의 임상적 특성

김형수,황성연,박철완,이 근 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

We present a retrospective study on the characteristics of head injury in the aged (more than 60 years of age). We selected 107 patients who visited the Chung Ang Gil Hospital due to head injury from January 1994 to December 1994. For comparison, data from 598 patients who were less than 60 years of age during same study period was used. In the aged, pedestrian traffic accident, slip or fall, and unknown trauma were common as a cause of head injury. The rate of intracranial mass lesion was higer in the aged. Contusional hemorrhage and subdural hematoma were common in the aged, while epidural hemotoma was the most common lesion in the young. The frequency of delayed lesion and intracranial mass lesion without skull fracture were more common in the aged. The rate of operative treatment and the mortality rate of the aged were higher than those of the young. This study revealed that the cause of head injury in the aged was different from that of the young, and the rates of intracranial mass lesion and de-layed lesion were higher in the aged, which increased the proportion of the patients with low GCS, and made the prognosis of the aged poor.

접착술식에 따른 전단강도 및 Bracket위치의 비교

김상철,국윤아,박윤경 대한치과교정학회 1991 대한치과교정학회지 Vol.21 No.3

The purpose of this study was to compare the bracket placement and the shear bond strength of indirect-bonded brackets with those of direct-bonded ones. Forty eight extracted human teeth were collected and attached with brackets and tested on shear bond strength, using Instron. Fourteen patients from Wonkwang University Dental Hospital were selected for direct bonding of brackets and their teeth were measured on bracket angulation and bracket height. The obtained results were as follows: 1.The shear bond strengths of incisors were higher in direct-bonding, group, rather than indirect-bonding group. But, the shear bond strength of premolars showed no significant differences between groups. 2.The bracket angulations of indirect-bonding group were preciser than those of direct-bonding group, especially in upper first premolars, lower lateral incisors, canines, premolars. 3.In bracket height, there were no significant differences between groups.

HFCVD법을 이용하여 제작한 n-형 다이아몬드 박막의 특성 연구

김병규,황윤식,권민철,김용,이재열,박홍준 동아대학교 기초과학연구소 2000 基礎科學硏究論文集 Vol.17 No.1

HFCVD법으로 암모니아 가스를 사용하여 n-형 도핑된 다이아몬드 박막을 제작하여, 기판온도와 암모니아 가스 첨가비에 따른 박막의 morphology의 변화를 조사하였다. 증착된 시료에 대한 SEM, Raman, XRD를 이용하여 박막의 특성을 분석하고, 도핑에 따른 전계방출 특성을 측정하였다. 양질의 n-형 도핑된 다이아몬드 박막을 증착시키기 위해 기판온도와 암모니아 첨가비에 따른 최적의 증착조건을 찾을 수 있었다. We fabricate n-doped diamond thin films by hot filament chemical vapor deposition method(HFCVD) using ammonia as a doping gas and investigate the effect of the substrate temperature and the ammonia gas ratio upon the diamond film morphology. The SEM, Raman spectroscopy, and the XRD analysis are executed to characterize film morphology. Field emission property of the film is measured also. We find optimum conditions of the substrate temperature and the ammonia gas ratio to deposit high quality n-doped diamond thin films.

글로벌 전자무역네트워크의 과제와 전망

윤광운,김철호 국제무역학회 2004 국제무역연구 Vol.10 No.1

글로벌 전자무역거래가 원활하게 수행되기 위해서는 원스톱의 지원시스템이 구축되어야 함에도 불구하고, 지금까지 글로벌 전자무역과 관련한 효율적인 비즈니스모델의 개발에 대한 본격적인 논의는 이루어지지 못하고 있다. 이러한 점을 감안하여 본 연구에서는 글로벌 전자무역의 효율적인 비즈니스모델을 모색하기 위한 방만으로써 글로벌 전자무역네트워크의 구축방안을 검토하였다. 이를 위하여 본 연구는 현재 한국과 일본을 비롯한 아시아를 중심으로 추진되고 있는 전자무역네트워크 구축사업을 중심으로 글로벌 전자무역 네트워크의 구축에 따른 당면과제를 분석하고, 향후 글로벌 전자무역네트워크의 합리적인구축방향을 제시함으로써 글로벌 전자무역의 활성화에 기여하고자 하였다. The rapid diffusion of e-commerce throughout the world has accelerated the introduction of global electronic trade. The essence of global electronic trade is to flow and exchange data among the related parties-businesses and counties. The proper linkage of trade networks are the fundamental elements to implement global electronic trade. In order to create a better environment for global electronic trade development, It is necessary for the related parties to make fit their information systems with those of their trading partners. In this paper, We focus on global electronic trade networks, which is at the heart of global electronic trade. The paper is organised as follows. Section II considers significances and requirements of electronic trade and electronic networks. Section III considers current state of global electronic trade networks. For example, The electronic trade networks such as Pan-Asian e-Commerce Alliance, Korea and Japan e-trade Hub Project, and ASEM e-Trade Network are examined. In spite of the advantage of these global networks, these have various problems that should be solved for global electronic trade. Section IV concentrates on the problems and the prospects faced in global electronic trade networks. The paper concludes with a summary which highlights a number of the key issues concerning global electronic trade networks.

엔드밀 절삭에서 Burr와 공구마멸 특성에 관한 연구

김원일,이진,이윤경,왕덕현,이관철 慶南大學校 附設 工業技術硏究所 1999 硏究論文集 Vol.17 No.-

본 연구에서는 엔드밀 절삭에서·버와 공구 마멸 특성에·관한 연구를 수행하였고 다음과 같은 결과를 얻을 수 있다. 출구 버의 생성은 알루미늄에서 절삭 깊이 1.5mm에서 0.1mm의 버가 발생되었고 황동은 그 보다 높을 0.2mm의 버가 생성되었다. 또한 측면 버에서도 황동이 알루미늄보다 높은 값을 보였으며 이것은 절삭에서의 버의 생성이 재료의 특성에 크게 기인함을 알 수 있다. 공구 마멸은 버의 발생이 많은 황동에서 크레이터 마멸과 날끝 마멸이 많이 발생됨을 알 수 있다. In this study, the properties of burr and tool wear in endmill cutting have been studied and the following conclusions could be obtained. As experimental results. exit burr height were obtained as 0.1mm for aluminum and 0.2mm for brass under the condition of 1.5mm in cut depth. And also side burr height for brass was higher than aluminum. It was found from the experimental results that burr formation in cutting largely depend on mechanical properties of machined materials. Tool wear properties of the brass, including crater wear and cutting edge wear, were also investigated.

SMEDDS를 이용한 난용성 약물의 용출율 향상

김계현,이윤석,배준호,지상철,박은석 성균관대학교 약학연구소 1999 成均藥硏論文集 Vol.11 No.-

ABSTRACT-A self-microemulsifying drug delivery system (SMEDDS) was developed to enhance the solubility and dissolution rate of poorly water soluble drug, biphenyl dimethyl dicarboxylate, DDB. The system was optimized by evaluating the solubility of DDB and the microemulsion existence range after the preparation of microemulsions with varying compositions of triacetin and surfactant-cosurfactant mixtures (Labrasol as surfactant (S) and the combination of Transcutol, Cremophor RH 40 and Plurol oleique as cosurfactant (CoS)). SMEDDS in this study markedly improved the solubility of DDB in water up to 10 mg/ml and the size of the o/w microemulsion droplets measured by dynamic light scattering showed a narrow monodisperse size distribution with an average diameter less than 50nm. The microemulsion existing range is increased proportional to the ration of S/CoS, however, it decreased remarkably as the oil content was more than 20%. In vitro dissolution study of SMEDDS showed a significantly increased dissolution rate of DDB in water (>12 fold over DDB powder), and SMEDDS also had significantly greater permeability of DDB in Caco-2 cell compared to powders.