한우, 칡소 및 제주 흑우 Calpain-Calpastatin 유전자 다양성

이승환,김승창,조수현,최봉환,Aditi Sharma,임다정,당창권,장선식,김재환,고문석,양보석,강희설 충남대학교 농업과학연구소 2013 농업과학연구 Vol.40 No.2

The aim of study was to investigate genetic diversity for the calpain/calpastatin gene in three Hanwoo breeds [(Brown (n=62), Brindle (n=81) and Jeju Black (n=30)]. Random samples from three breeds of Hanwoo were selected and genotyped for the 7 SNPs of calpain/calpastatin using TaqMan method. Allele frequencies were investigated for CAPN1/CAST gene. Allele frequency of CAST2 SNP was 0.75, 0.59 and 0.22 for Brown, Brindle and Jeju black, respectively. The CAST3 revealed allele frequency of 0.59 and 0.57 in Brown and Jeju Black, while it showed very low allele frequency (0.07) in Brindle. In particular, favorable allele (G allele) for the CAPN1-2 SNP which was shown a strong association with tenderness in Taurine and Indicine cattle revealed 16% and 17% higher allele frequency in Brown Hanwoo (0.82) comparing Brindle (0.66) and Jeju Black Hanwoo (0.65). AMOVA demonstrated that among population variance occupied only 10% of total variance and among individual variance was 0%, while within individual variance was 90% of total variance. This result showed that population effect contributed very small portion of genetic to these three Hanwoo breeds, while within individual variance contributed large portion of genetic diversity within these Hanwoo breeds. In conclusion, three Hanwoo breeds (Brown, Brindle and Jeju black) showed a genetically homogeneous based on the 7 SNPs of CAPN1/CAST gene and it came from same ancestor to form modern Hanwoo breed.

비만증 환자에서 한약제에 의한 체중 감소효과

Oh, Seung-Joon,Jeong, In-Kyung,Kim, Young-Seol,Choi, Young-Kil,Paeng, Jeong-Ryung,Bae, Jung-Hwan,Shin, Hyun-Dae 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Seung-Joon Oh, In-Kyung Jeong, Young-Seol Kim, Young-Kil Choi, Jeong-Ryung Paeng¹, Jung-Hwan Bae and Hyun-Dae Shin²Department of internal Medicine, College Medicine, Endocrine Research Institute¹. Department of Rehabilitation, College of Oriental Medicine², Seoul, korea. Bady Fat Reduction Effects of Red Ginseng Compound Preparation on the Patients with Obesity. Proceedings of International Symposium on East-West Medicine, Seoul. 244-254, 1999.-Obesity can be defined as a metabolic disease due to an increased state of fat tissues caused by an imbalance of calorie intake and use. Recently, in Korea by improvement and westernization of food intake, along with decrease in exercise activities, the prevalence of obesity has increased greatly. Our objectives were to study stability and effects of decrease in body fat by administering red ginseng compound preparation (known to have body fat decreasing effects in laboratory animals) to obesity patients on low calorie diets. Changes in weight and body fat were measured while carrying out calorie-restricted diets on patients for 4 weeks, then administering red ginseng compound preparation for another 4 weeks. The patients were 20 people whose BMI were 25kg/㎡ or over and whose percent body fat was also 30% or over when tested by bioelectrical conductivity. 1. Changes in weight were from 70.04kg(base line) to 67.43kg(after taking red ginseng compound preparation). 2. In similar sense, BMI decreased from 27.12kg/㎡(base line) to 26.56kg/㎡(after dieting), and further to 26.01kg/㎡ (after taking red ginseng compound preparation). The BMI seemed to decrease significantly compared to the baseline after the use of red ginseng compound. 3. Waist hip ratio was changed from 0.8858(base line) to 0.8728, but it was statistically insignificant. 4. The percent body fat was 35,16%(base line), 33.87%(after dieting), and 31.68%(after taking red ginseng compound preparation). 5. Complete blood cell count and blood chemisrty remained unaffected by the administration. 6. In concern to endocrinologic studies, T3 decreased from 118.7 to 98.2ng/dL, and T4 increased from 8.8 to 9.2㎕/ dL. Epinephrine showed a tendency to decreased from 0.27 to 0.25 ng/mL, and norepinephrine increased from 0.39 to 0.44ng/mL. 7. Leptin was not changed. 8. Some patients complained adverse effects; constipation(5 patients, may be due to diet therapy), fatigue (2 patients), pruritus(2 patients), flushing(s patients), dizziness(3 patients) and epigastric discomfort(2 patients). However their symptoms were mild, so medication did not stopped. In conclusion, loss of weight without significant side effects was observed during low calorie diet and red ginseng compound preparation administration. This is thought to be in relation to sympathetic nerve system rather than adrenal gland. Also, further long0term studies should be required, since the observed results were based on short-term changes in weight.

메트암페타민 정맥주사 남용후 발생한 뇌경색 2예

김종환,김동선,김상진,예종수,김성은,김응규,허경 대한신경과학회 1998 대한신경과학회지 Vol.16 No.5

Rifampicin에 의한 것으로 추정되는 위막성 대장염1예

김수현,이은우,정종혁,문승현,김동한,양혁승,오영상,김호동,김도현,박혁,박정환,박경옥,이영직 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Pseudomembranous colitis, caused by altering the normal colonic flora and allowing the multiplication of Clostridium difficile, is an deleterious adverse effect of antibiotics. But it is rarely reported by rifampicin. Rifampicin is one of the first line drug in the treatment of tuberculosis and many patients are exposed to its potential adverse effects. We experienced a patient that had abdominal discomfort and hematochezia due to pseudomembranous colitis after receiving antituberculous medication, and which was probably caused by rifampicin. A 82 years old man was admitted with abdominal discomfort and hematochezia for one week. On the past history he had been diagnosed as endobronchial tuberculosis about 4 months ago. Colonoscopy revealed multiple discrete whitish mucosal lesion on rectosigmoid colon, and histologic findings were consistent with pseudomembranous colitis. The antituberculous agents were discontinued and vancomycin was administered. The patient's symptoms were resolved within several days. There was no recurrence after reinstitution of the antituberculous agents excluding rifampicin. We report here on a case of pseudomembranous colitis probably due to rifampicin.

음양곽 추출물 중의 항산화성분의 분리 및 성질

김성렬,김진환,김승겸 보건장학회 1992 보건장학회보연구논문집 Vol.14 No.-

Gelation에 의한 방사성 폐기물의 안정화/고형화 : Ca 및 Zr 첨가에 따른 이성분계의 열적 및 수화학적 안정성 Thermal/Hydrochemical Stability of a Binary System with Ca or Zr as an additive

김인태,박환서,유승곤,김환영,김준형 한국공업화학회 2004 응용화학 Vol.8 No.1

In the previous study, we suggested a new concept, named as GRSS(Gel-Route Stabilization/Solidification) and investigated a material system applicable to volatile radioactive waste, a reaction condition and chemical limitations. From these results, this paper investigated the effect of some additives, which have been considered as the major component of ceramic waste forms(apatite and sodium zirconium phosphate), on the thermal stability and chemical durability. The Si-P system with Ca at appropriate composition shows good thermal stability but low chemical durability while the Si-P system with Zr shows relatively low thermal stability but relatively high chemical durability.

겔화 반응 및 열처리한 금속염화물의 결정 및 구조특성

김인태,박환서,유승곤,김환영,김준형 한국공업화학회 2003 응용화학 Vol.7 No.2

A new concept for the stabilization and solidification of volatile radioactive wastes via gelation in a simple material system is introduced in this paper. Using sodium silicate as a reaction module and phosphoric acid as a catalyst or stabilization agent. CsCl is chemically converted to thermally stable compounds. The heat-treated product at 1000℃ contained a cristobalite crystalline framework and a glassy phosphorus-rich phase with a high Cs content. The morphology looked like honey flowing on the honeycomb. From TG/DT analysis, Cs could not be vaporized below 1300℃ by changing the aging conditions and molar ratio of Si/p. As a new concept, GRSS(gel-route stabilization and solidification) could give us the chance to make the high temperature waste conditioning process more stable and economical.

서울의 PPNG 발생 빈도(1991-1992)

김재홍,윤기범,박평원,김영진,전경민,김영태,김중환,곽호,구상완,송민석,유옥,지혜구,김동원,문상은,박영립,정승호,성범진,성순제,엄주용,황정열,이기홍,이주협,전태진 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.1

The prevalence of PPNG among pretreated gonorrhea cases isolated at the STD clinic of Choong-Ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1991, 123 strains of N.gonorrhoeae were isolated, among which 58(47.1%) were PPNG. In 1992, 98 starains of N.gonorrhoeae were isolated, among which 51(52.0%) were PPNG. In all, 109(49.3%) strains were found to be PPNG among 221 strains isolated between 1991-1992. The prevalence of PPNG in Seoul showed increased tendency till 1989, thereafter, it has been stationary or slightly decreasing.

유도 '되치기 본'의 개선 방안에 관한 연구

김의환,김도준,김규수,김관현,김종달,최종삼,조용철,박순진,윤익선,안병근,정 훈,김미정,한성철 龍仁大學校 武道硏究所 1999 武道硏究所誌 Vol.10 No.1

The purpose of this study was to reform practically a Korean Judo's Doechigi-Bon(Forms of Counterattack, judo's Gaeshi no Kata, Judo's Uradori no Kata, Judo's Gonosen no Kata) that was established in 1955 Korea, according to changing of techniques by Judo's modernization, in order to have Judo's carefulness and systematic diffusion. Reform procedure of Judo's Doechigi-Bon was 1st stage, Questionnaire survey 303 judokas, 2nd stage, Technical seminar by judo experts(12 judo professor) 4 times, 3rd stage, wording report for reform, 4rd stage, Discussion and judgement of Teaching and Judgement commission of Korean judo Association(KJA), 5th stage, Public hearing for reform in KJA, 6th stage, Report and decision of board of directors in KJA, 7th stage, public publication of Judo News(No.53) in KJA. Basic principle of reform of Judo's Doechigi-Bon were as table 1. Table 1. Basic principle of reform of Judo's Doechigi-Bon ------------------------------------------------------------------------------- Items Reformed Key Points of Judo's Doechigi-Bon ------------------------------------------------------------------------------- 1. Structure 1) Grand classification : Classified by 3 parts(1,2,3Gyo) 2)Medium classification : Te waza, Goshi waza, Ashi waza devided per each part(Gyo) 3)Sub-classification : Classified five techniques per each part(Gyo) 2. Contents 1) Selected established techniques as possible 2) Considered rationalty and overlapping of counterattack techniques 3. Decision of Conterattack techniques 1) Refered to results of Basic Questionnaire survey 2) Priority to decisions of Judo expert technical seminar -------------------------------------------------------------------------------- Reformed Korean Judo's Doechigi-Bon(Forms of Counterattack techniques-KJA, 1999) are as follows: 1. Gyo; ① Uki otoshi -> Uchi mata ② Harai goshi -> Harai goshi gaeshi ③ O soto gari -> O soto gake ④ Ko uchi gari -> Sasae tsurikomi ashi ⑤ O uchi gari -> Ko soto gari 2. Gyo; ① Ippon seoi nage -> Okuri eri jime ② Tsuri domi goshi -> Uki waza ③ Okuri ashi harai -> Okuri ashi harai ④ Ko soto gari -> Tai otoshi ⑤ Hiza guruma -> Hiza guruma 3. Gyo; ① Kata guruma -> Sumi gaeshi ② Tai otoshi -> Ko soto gari ③ Hane goshi -> Harai tsurikomi ashi ④ Uchi mata -> Tai otoshi ⑤ Tomoe nage -> O uchi gari

<감자>에 나타난 정신사건과 물리사건의 인과관계

김승환 ( Kim Seung Hwan ) 현대문학이론학회 2019 現代文學理論硏究 Vol.0 No.79

이 논문은 <감자>의 핵심사건인 복녀살인사건을 정신사건과 물리사건으로 분석한 글이다. <감자>에는 복녀의 죽음이 명료하게 묘사되어 있지 않으며 그 때문에 정신사건인 원인(복녀의 원한)과 물리사건인 결과(복녀의 죽음) 사이의 인과관계가 맞지 않는다. 이 논문에서는 복녀살인사건의 인과관계 상치현상을 김재권(Jaegwon KIM)과 데이비슨(D. Davidson)의 사건이론(theory of event)으로 분석했다. 복녀살인사건은 ‘어떤 시간에[t] 복녀가 왕서방에 대하여[x] 원한을 품었다[P]’는 정신사건이자 복녀 자신이 죽는 물리사건이다. 현실의 물리사건과 달리 마음의 정신사건은 믿음, 의도, 욕망, 희망, 지각, 인식, 기억, 생각, 느낌, 감정, 결심, 각성 등이 구성한 사건이다. 소설의 정신사건은 소설텍스트에서 묘사된 허구적 사건이며 현실의 물리사건과 같은 조건[x, P, t]으로 구성된다. 따라서 소설의 정신사건을 단순한 상상으로 규정하기보다 이야기 전개의 필연적 요소로 보고, 플롯의 개연성을 보완하는 소설적 장치로 볼 필요가 있다. 그것은 물리사건만으로 복녀살인사건을 분석했을 때 생기는 여러 가지 불확실성과 불확정성을 없앨 수 있다는 뜻이다. 한편 미완의 텍스트는 창의적 독서의 주체인 독자가 완성한다. 이 과정에서 독자의 상상력이 작동하는데 이 역시 정신사건이다. 가령 ‘복녀는 왕서방에게 낫을 빼앗겼다.’로 묘사된 소설의 물리사건은 독자에게 ‘‘복녀는 왕서방에게 낫을 빼앗겼다.’고 믿는다.’로 바뀌면서 정신사건이 된다. 또한 ‘복녀는 왕서방의 낫에 찔려 죽었다.’와 같은 텍스트의 물리사건은 독자에게 ‘‘복녀는 왕서방의 낫에 찔려 죽었다.’고 믿는다.’로 바뀌면서 정신사건이 된다. 이 두 문장의 속성예화(exemplification)에서 보듯이 독자가 ‘믿는’ 독서행위 역시 일종의 정신사건이다. 이처럼 타르스키에 근거하여 대상언어(object language)와 메타언어(metalanguage)의 층위를 나눔으로써 김동인 특유의 생략과 비약이 낳은 텍스트를 완결된 이야기로 읽을 수 있다. 이처럼 소설텍스트에서도 정신사건이 존재하고 독자의 창의적 독서과정에서도 정신사건이 작용하며 작가의 창작과정에서도 정신사건이 작동한다. 물리사건과 정신사건의 이론적용은 <감자> 이외의 다른 작품에도 적용될 수 있다. This essay is to analyze kernel event of Gamza by mental event and physical event. Kernel event of Gamza is the death of Bokyne who was born with noble disposition but changed to bulger disposition according to the environment under the colony of Japanese Imperialism. In Gamza, death of Boknye has not described clearly. Climax of Gamza deviates on kernel event as in “Mr. Wang. Let you problem!” Boknye decides not to make a problem. It is anomalous causation. Actually, kernel event finished with a result of Boknye’s death. On the other hand, Boknye’s hatred[cause] - Boknye’s death[effect] is not matched. Moreover, mental event as a cause and physical event as an effect are not match well. Nobody doubt story line due to its natural story stream and organized possibility of cause and effect. We can classify as twofold; ‘①Bokyne desires to kill Mr. Wang.’, ‘②Bokyne killed Mr. Wang.’ In these structure, ①Bokyne desires to kill Mr. Wang.’ is mental event which could be or could not be happened in real world, ‘② Bokyne killed Mr. Wang.’ is physical event which could be happened in real world. The difference may be decided by synthetic predicate as;‘desires to kill’ and ‘killed.’ This synthetic difference results in the semantic difference. In event theory, mental event occurs in the human mind. Feature of mental event is not exist in real world and don’t have spatiotemporal location. Mental event in the possible world is event as well as in the actual world. Main theories of this essay based on the event theory by Jaegwon KIM and Donald Davidson. Death of Boknye consists of object[x], property[P] and time[t] as set [x, P, t]. It is twofold events; mental event and physical event. Unlike physical event, mental events are belief, purpose, perception, remember, decision, hope, recognition, thinking, feeling, awakening etc. Mental event must be read with relation to plot, causation and probability. If reader read with physical event, reader can’t get rid of uncertainty of story line. Mental event might be a good way to analyse Korean Modern short story. Mental event in Gamza is a fiction consisting of object(x), property(P), time(t) as well as in actual event. In this reason, mental event in short story is not only imagination, but necessary apparatus for plot, probability and story line. Within this theory, reader should read mental event with plot and story line. If reader read story with only physical event of Boknye’s death, reader can’t read chain of causation. There is uncertainty and unpredictability of who must be accused the killing. Reader, the subject of reading, may accomplish the text’s empty part written by writer. In the reading, reader’s imagination will work properly. As Tarski said, we can exemplify one event as object language and metalanguage. Metalanguage is language about original sentence as an event as follow; ‘Boknye was robbed of sickle by Wang’ could be rephrased as ‘Reader believes that ‘Boknye was robbed of sickle by Wang’’ It is property exemplification said by Jaegwon KIM. If we differentiate object language and metalanguage by Tarski Skema, we can read story completely. Imagination is mental event. As we see, mental event in short story is very important reading by reader, and mental event work in creative writing by writer.