IgG GM₁ 항체와 Campylobacter jejuni 항체와 관련된 급성 운동축삭형 신경병증

홍경훈,김승현,이영배,이영주,김희태,김주한,김명호 대한신경과학회 1997 대한신경과학회지 Vol.15 No.5

반측안면소체증의 측두골 전산화 단층촬영소견

한종규,한경렬,백병준,김형환,배원경,김일영 순천향의학연구소 2005 Journal of Soonchunhyang Medical Science Vol.11 No.1

Hemifacial microsomia(HFM) is a craniofacial disorder and complex malformation syndrome with a variable and asymmetric malformation involving first and second pharyngeal arch derivatives. Multiple etiological mechanisms for HFM have been considered. Mechanisms proposed include genetic factors, early embryogenesis insults involving abnormal neural crest development and migration, and stapedial artery hematoma. HFM is the second most common craniofacial malformation but has been rarely reported in korea, and we report five cases of HFM in temporal bone CT findings. The temporal bone CT findings of five patients aged 6 days and 19 years(mean, 9 years) with hemifacial microsomia were reviewed and evaluated. Particular attention was focused on auricular malformation, external auditory canal, volume of middle ear cavity, ossicular anomaly, facial nerve anomaly and inner ear anomaly. In all patients, temporal bone CT scans revealed the stenosis or atresia of external auditory canals, decreased middle ear cavities, matoid underdevelopment and ossicular anomalies including ossicular ankylosis, but only one patient showed facial nerve or inner ear anomaly. In conclusion, temporal bone CT scan is a useful diagnosis modality of hemifacial microsomia, which is especially more useful in preoperative evaulation and estimation of postoperative prognosis that demonstate middle and inner ear anomalies.

우리나라 논 관개용 지하수 수질 특성

김진호,조광래,임수정,이경자,경기천,엄미정,김희권,김찬용,이영한,이신찬,윤순강 한국환경농학회 2003 한국환경농학회지 Vol.22 No.4

This study was carried out to evaluate the status of the groundwater quality for paddy fields irrigation in Korea. Water samples were collected at 130 sites throughout the country. Samples were collected at three seasons-April, July and October-in 2000. According to our survey, the groundwater was found to be suitable for irrigation purpose. Average EC was shown 0.286 dS/m. Nitrate-nitrogen and Cl^(-) concentration was 5.6 ㎎/L, 32.95 ㎎/L which satisfied the Korean Standards for Irrigation Water. Nitrate-nitrogen concentration in each province was shown as following orders: Jeju (11.17 ㎎/L) > Chungnam (8.16 ㎎/L) > Gyeongbuk (6.64 ㎎/L) > Gyounggi (5.91 ㎎/L) > Chungnam (4.95 ㎎/L) > Gyeongnam (3.91 mgk) > Jeonbuk (3.50 ㎎/L) > Jeonnam (3.27 ㎎/L) > Gangwon (2.91 ㎎/L). The concentration by sampling seasons were October (6.62 ㎎/L) > July (5.88 mg&) > April (4.78㎎/L). As the soil of Jeju Province is usually derived from volcanic ash soils mainly used for upland drops, it may influence the nitrate-nitrogen concentration of groundwater. The amount of rainfall also influence the water quality. But the COD_(Cr), were shown April (3.17㎎/L) > July (2.91 ㎎/L) > October (2.40 ㎎/L), it is highly related in the basal dose of organic matter fertilizers. This study demonstrated that groundwater quality was suitable for irrigation, but continuous monitoring is recommended for agricultural policy and developing OECD agricultural environment indicators.

배달 미니 게임 개발:"최고의 웨이터를 꿈꾸며"

김정훈,정한교,김영옥,김중곤,박정윤,윤진성,김경식 호서대학교 반도체제조장비국산화연구센터 2001 반도체장비학술심포지움 Vol.2001 No.-

본 미니 게임은 웨이터라는 직업을 모티브로 하여서 남녀노소 누구나 재미를 느낌과 동시에 기억력 향상시켜 주는 게임제작이라는 목적아래 제작되었다.본 논문에서는 이 게임의 제작과정을 기술하고자 한다.이 게임은 제3회 AGC(한국 아마추어 게임제작 공모전)에서 우수 작으로 선정되었다.

경찰관의 운동참여에 따른 직무 Stress와 직무만족에 관한 연구

김종달, 남덕현, 이한경, 반종진 용인대학교 체육과학연구소 2000 體育科學硏究論叢 Vol.10 No.1

This study is for the purpose of examining effects related to duty stress & duty satisfaction due to Police of officers' Physical exercise participation, helping more efficient duty Performance, and positive self-formation. Furthermore, providing basic data that can be helpful to the improvement of police duty. The objects of the study were police officers who were taking part in education program in Police Comprehensive Academy, and the number of police officers who answered the questionnaire is 356 police officers, but data used for real analyzation consist of 300 police officers. The tools for the study were based on Ivancevich's duty stress model in order to measure stress. And also questionnaire used on Kim yoon hee, Kim mae ja, Jo kyung soon, Lee hart kyung's study was used as a complementary tool. The instrument for measuring duty satisfaction rate was developed by Paula. And I used the instrument based on questionnaire that was used by Ko hee soon, Park ki hyung, Kim bum sik, Lee jong kil, Lim bun jang, Jo young chang, Hackeman, Lawlar and Oldham's study. Data analysis is Processed statistically with SPSS/PC+, I Performed T-verification, ANOVA-verification in accordance with the purpose of study after getting the percentage and the real number in case of general characteristics of the objects, and examine an average and standard variation in case of duty satisfaction and duty stress rate. And I set an err rate to 0.5. I verificated co-relation between stress and duty satisfaction with Pearson Correlation Coefficient. The result of the study is as follows, The first, among sociological characteristic and external factor of duty satisfaction, The married is more significant statistically(p< .01, p<.05) compared to the unmarried in terms of compensation system and working condition , which are subfactor of duty satisfaction . In terms of the length of one's service, the longer service term one has the higher significance level one shows in compensation system, working condition, safety, and external factor which are sub-factors of duty satisfaction In terms of an academic background, one who graduated from a high school shows significance statistically only in working condition which is a subfactor of duty satisfaction compared to other people (p<0.5) The second, among sociological characteristic and internal factor of duty satisfaction, the married is more significant statistically(P<.05) compared to the unmarried in terms of achievement which is a subfactor of duty satisfaction. In terms of age the older one shows higher significance level in stability which is a subfactor of duty satisfaction compared to younker one(p<.05) In terms of the length of one's service the longer service term one has ,the higher significance level one shows(p<.01, p<.05). The third, in terms of duty stress due to sociological variable, the married is more significant statistically(p<.05) in case of stress stems from police duty than the unmarried Interms of age, welfare and duty stress are significant statistically(P<.05) Interms of the length of one's service, police's work is significant statistically(P<.05). One who graduated from junior college is significant statistically in police's work, welfare, stress and gets a lot of stress in personal relations(p<.05). The forth, groups participating in exercise are more significant statistically in stability(p<.001), feeling of stability(P<.001), achievement(p<.001), internal factor(p<.01), external factor(p<.05) than croups not Participating in exercise. The fifth, groups participating in exercise are more significant statistically only in personal management than groups not participating in. The sixth co-relation between duty satisfaction and duty stress is r=-0.3814, (P<.001) ,which shows opposite co-relation. so, a result the more stress one has, the lower duty satisfaction he gets.

Analysis of KAP1 expression patterns and human endogenous retrovirus Env proteins in ovarian cancer

Kyung‑Yoon Jeon,Eun‑Ji Ko,Young Lim Oh,Hongbae Kim,Wan Kyu Eo,김아리,Han Gyu Sun,Meesun Ock,Ki Hyung Kim,Hee‑Jae Cha 한국유전학회 2020 Genes & Genomics Vol.42 No.10

Background Human endogenous retroviruses (HERVs) constitute around 8% of the human genome and have important roles in human health and disease, including cancers. Previous studies showed that HERV envelope (Env) proteins are highly expressed in cancer tissues and co-related with cancer progression. KAP1 has been reported to play a key role in regulating retrotransposons, including HERV-K, through epigenetic silencing. Objective The relationship between KAP-1 and HERV Envs expressions was analyzed only in tumor cell lines and has not yet been studied in cancer tissues. In this study, we analyzed the expression patterns and relationship between KAP1 and HERV Env proteins in ovarian cancer tissues. Method The expression patterns of KAP-1 and HERV Env proteins, including HERV-K and HERV-R, were analyzed in ovarian cancer tissue microarrays that contained 80 surgical specimens, including normal ovary and malignant ovarian cancers. Results The expression of HERV-R Env and KAP1 proteins is signifcantly higher in ovarian cancer compared with normal ovary tissues. However, the expression of HERV-K Env did not change signifcantly in cancer tissues. The expression patterns of HERV-K Env and HERV-R Env signifcantly increased in early stages of cancer and KAP1 expression was higher in certain stage and types of cancers. However, the expression of HERV-K Env, HERV-R Env, and KAP1 did not change in diferent age groups. The correlation between the expression of KAP1 and HERV-Env, including HERV-K and HERV-R, was not signifcantly correlated. Conclusions The results of this study showed that there was no signifcant correlation between the expression of KAP1 and HERV Env proteins in ovarian cancer tissues, unlike studies with cell lines in vitro. These results suggest that the actual expression of HERV Env proteins in ovarian cancer tissues may be regulated through various complex factors as well as KAP1.

한국 행정개혁의 성과 평가 연구

김경한(Kim Kyung-Han) 서울행정학회 2005 한국사회와 행정연구 Vol.15 No.4

For the past ten years, Korean government have drove the government reform but many questions on the performance of the reform are raised by many researchers. The objectives of this study are to evaluate the performance of various government reform measures, to find out the obstacle factors to make those reform measures fail and to suggest the desirable methods and strategy of government reform. In order to achieve those research objectives, I did evaluation synthesis through content analysis on ten theses analysing the performance and the operation realities of the performance-based management programs such as Performance-based reward system, Management by objectives(MBO) and Open-system in higher civil service, which were introduced to Korean government as the tools of government reform during the period of Dae Jung Kim's administration. In conclusion, the performance-based management programs including Performance-based reward system, MBO and Open-system in higher civil service have no effectiveness because those programs are failing to accomplish the introduction objectives of each programs. The major reasons why those programs don't have effectiveness are identified as the cultural restraint, which occur by cultural inconsistency between the culture of public organization and the reform measures and cause government reform not to success. In addition, it is found out that symbolic politics is the main cause to push on with the introduction of performance-based management programs in spite of their incongruity to public culture and the probability to have no effectiveness.

협동적 신체활동이 유아의 자아개념 향상에 미치는 효과

김한나 ( Kim Han Nah ),이경화 ( Lee Kyung-hwa ) 한국실천유아교육학회(구 한국Montessori교육학회) 2018 실천유아교육 Vol.23 No.2

본 연구는 협동적 신체활동이 유아의 자아개념 향상에 효과적인지 목적을 두고 이를 확인하고자 실험연구를 실시하였다. 연구의 대상은 서울에 위치한 국공립어린이집에 재원중인 만 4세 유아를 대상으로 하였다. 이중 실험집단은 H어린이집에 재원 중인 만 4세 유아 13명, 통제집단은 J어린이집에 재원 중인 만 4세 유아 13명이다. 실험집단 유아들은 6주 동안 주 2회씩, 총 12회의 협동적 신체활동 프로그램에 참여하였고, 통제집단 유아들은 6주 동안 만 4세 누리교육과정 신체활동에 참여하였다. 유아의 자아개념 측정을 위한 도구로 이경화, 고진영(2015)의‘유아용 자아개념 검사’를 사용하였고, 분석은 SPSS WIN 24.0 프로그램을 이용하여 집단별 차이검증 t-test를 실시하였다. 연구결과는 다음과 같다. 첫째, 협동적 신체활동 프로그램에 참여한 실험집단이 누리교육과정의 신체활동에 참여한 통제집단 보다 유아의 총 자아개념이 향상된 것이 확인되었다. 둘째, 하위영역별 자아개념에 있어서는 협동적 신체활동 프로그램에 참여한 실험집단이 누리교육과정의 신체활동에 참여한 통제집단 보다 인지적 자아, 사회적 자아, 신체적 자아 영역에서 통계적으로 유의하게 높은 점수가 확인되었으나, 정의적 자아 영역에서는 실험집단과 통제집단 간에 유의한 차이가 확인되지 않았다. 본 연구의 결과는 협동적 신체활동 프로그램이 누리교육과정의 신체활동보다 유아의 자아개념을 향상시키는데 긍정적인 효과가 나타났다. The purpose of this study was to investigate the effects of cooperative physical activities on the self-concept of young children. For this purpose, an experimental study was conducted to determine whether cooperative physical activities are effective in improving the self-concept(physical, cognitive, social, emotional) of young children. This study used the standardized 'Self-concept examination for young children', produced by Lee Kyung-Wha and Ko Jin-young (2015), as a tool for measuring the self-concept of young children. The pre- and post-test were conducted through individual interviews using free-choice activity time and after-school hours in both experimental group and control group. The results of this study are as follows. Firstly, it was confirmed that the overall self-concept of the children in the experimental group participating in the cooperative physical activities program improved more than the self-concept of the children in the control group participating in the physical activities of the Nuri curriculum. Secondly, in the sub-domains of self-concept, the experimental group participating in the cooperative physical activities program showed a statistically higher score in the cognitive self, social self, and physical self than the control group participating in physical activities of the Nuri curriculum, but there was no significant difference in emotional self-concept between the experimental group and the control group. The results of this study showed that the cooperative physical activities program had a more positive effect on the improvement of the self-concept of young children than the physical activities of the Nuri curriculum, and it is suggested that if cooperative physical activities are actively used in the education field of young children, the children's self-concept can be improved more effectively.

제 1형 신경섬유종증 환자에서 발생한 위장관 간질종양 1예

원경준,이준,변유미,조민근,한경택,김원,홍란,임성철,김경종,김영대,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Gastrointestinal stromal tumor (GIST) is the most common non-epithelial neoplasm arising in the gastrointestinal tract, but this tumor is rarely seen in association with type l neurofibromatosis (NFl) Generally, the majority of GISTs are isolated neoplasm and they are sporadically found in the stomach, but the GISTs in NFl patients are usually multiple and usually found in the small intestine. We report a case of multiple GISTs in the jejunum of a 63-year-old woman diagnosed as NFl accompanied by complication of gastrointestinal bleeding, In this case, Patient had multiple cafe-au lait spots and neurofibroma on skin and had freckling on axilla and groin, and then, we made a diagnosis of NFl. Gastrointestinal bleeding is controlled by resection of multiple GISTs. Generally, only 3-5% of all gastrointestinal bleeding comes from the small bowel. Causes of small intestinal bleeding are angiodysplasia, neoplasm, NSAIDs induced ulcer etc. but, If patients have NFl accompanied by complication of gastrointestinal bleeding, GISTs on small bowel must be considered.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.