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소셜미디어 분석을 활용한 재난안전산업 육성정책 수립방안
임수정,박덕근,Lim, Sujung,Park, Dugkeun 기술경영경제학회 2018 Journal of Technology Innovation Vol.26 No.1
다양하게 변화하는 재난양태와 기후변화로 인한 빈번한 재난발생뿐 아니라 생활수준 향상 등의 이유로 재난안전에 대한 국민적 관심이 증대되고 있다. 이와 연계하여 재난안전 산업에 대한 요구도 증가하고 있다. 그 동안 다양한 재난안전산업 육성 및 활성화 정책이 수립되었지만, 국가주도의 정책이 대부분이었고, 민간분야와 국민관심도가 반영된 정책은 부재한 상황이다. 따라서 본 연구에서는 국민관심도를 고려한 재난안전산업 육성방안 수립을 위하여 소셜미디어 분석을 활용하는 방안을 제안하고자 하였다. 재난안전분야의 국민관심도를 분석하기 위하여 최근 3년간의 소셜미디어를 대상으로 분석을 실시하였다. 분석 결과, 국민은 실제 발생했던 재난에 대한 내용, 즉각적으로 실생활에서 필요한 분야에 대해 관심도가 높은 것으로 나타났다. 또한 실제로 경주 지진발생 당시 재난 관련 소셜데이터가 급증하는 것으로 나타났고, 뉴스에서는 피해상황 등에 관한 내용이 많은 반면, 트위터와 블로그에서는 구호물품, 대피요령 등에 관한 내용이 주를 이루고 있는 것을 확인하였다. 본 연구의 결과로 국민적 관심도를 분석하기 위한 방법으로 소셜미디어 활용방안에 대한 가능성을 확인하였고, 재난안전산업의 민간분야 확산 차원에서 국민관심도를 반영한 재난안전산업 정책 수립방안을 제안한다. The general public's interest level towards safer life is increasing due to not only ever-changing faces of disasters and increased frequency of climate-change related disasters but also enhanced standard of living. Demand for disaster-safety industry is also increasing. Several policies for disaster-safety industry have been introduced. The policies, however, did not fully reflect the level of people's interest. This study is to investigate possible ways to reflect general public's interests towards disaster-safety industry using social media analysis, so that disaster-safety industry can be properly promoted. To examine the level of general public's interest, social media data during the last three years were compiled and analyzed. It was found that the interest level was highest towards, firstly, information on just-happened real disasters, secondly, necessary knowledge in real life which could be applied immediately if disasters strike. It was also confirmed that social media was useful in analyzing people's interest level quickly, because social data have been found to be sharply increased during the 2016 Gyeongju Earthquake in Korea. This study suggests applicable plans for disaster-related industry promotion based on social media data using general public's interest level.
Intense Pulsed Light Sintered Core-Shell Nanoparticles for Organic Photovoltaic Devices
임수정,이지연,유재웅 한국고분자학회 2019 Macromolecular Research Vol.27 No.11
A fast and low-cost fabrication process using intense pulsed light sintering of metal nanoparticles was studied. Silver, copper, and four different copper-silver core-shell alloy nanoparticles were synthesized. The composition and resistivity of the sintered metal electrodes were studied. The resistivity of the silver electrode formed through nanoparticle sintering was comparable to that of a conventional solution-processed silver electrode. The performance of the device prepared using the copper nanoparticles only was low due to the oxidation of copper in the air. The current density-voltage (J-V) characteristics of the devices fabricated using the synthesized core-shell nanoparticles revealed that the alloy ratio up to approximately 2 did neither affect the performances nor the lifetime of the devices. As the content of copper increased, the device performance decreased due to the oxidation of copper. Usage of the sintered metal alloy electrodes resulted in the reduction of cost by 33% compared with the conventional silver electrode.
[123I]Idoxifene 합성과 유방암의 세포섭취에 관한 연구
임수정,임상무,양승대,서용섭,전권수,안순혁,유국현,조영섭 대한핵의학회 2000 핵의학 분자영상 Vol.34 No.5
Purpose: Idoxifene is currently entering phase Ⅱ clinical trials for the treatment of advanced breast cancer. The radiolabeled idoxifene using 123I provides an opportunity for clinical pharmacology with single photon emission computed tomography (SPECT). The purpose of this study was to prepare radiolabeled idoxifene using 123I and to determine its cell uptake of breast cancer cell line. Materials and Methods: With a view to evaluating new anticancer drugs, we are investigating the novel antiestrogen pyrrolidino- 4-iodotamoxifen (idoxifene). [123I]Idoxifene has been prepared in no-carrier-added form using a tributyl stannylated precursor which has been synthesized by means of (2-chloroethoxy)benzene with (±)-2- phenylbutanoic acid on the basis of previously reported standard methods. The biodistribution and dynamic behavior of the compound were investigated using the comparative breast cancer cell line, MCF-7 (estrogen receptor-positive) and MDA-MB-468 (non-estrogen receptor). Results and Conclusion: Acylatn of (2-chloroethoxy)benzene with (±)-2-phenylbutanoic acid gave the versatile ketone (81%) which reacted with 1,4-diiodobenzene to give triphenylethylene as a mixture of E and Z geometric isomers, which were separated by the recrystallization in ethanol. The E-isomer was treated with pyrrolidine to give idoxifene (67%). In order to incorporate radioactive iodine into the 4-position, the 4-stannylated precursor was prepared (30%). The yield of radioiodination was 90-92% with a high radiochemical purity greater than 98%. The ratio of tumor uptake of the breast cancer cell line between MCF-7 and MDA-MB-468 was about 1.7.
농양이식백서에서 99mTc , 188Re 직접표지항체의 비교
임수정,최창운,최태현,임상무,우광선,정위섭 대한핵의학회 1999 핵의학 분자영상 Vol.33 No.1
Purpose: We investigated the direct labeling method of antibody with 99mTc and 188Re and examined the stability and function of these labeled compounds in in vitro and in vivo. Materials and Methods: Disulfide bond of nonspecific human IgG was reduced to -SH group by 2-mercaptoethanol. Stannous ion was used to reduce 99mTc and 188Re. The stability of 99mTc-IgG and 188Re-IgG was estimated upto 24 hrs. Biodistribution was evaluated in abscess bearing rats at 4 and 24 hr post-injection of 99mTc or 188Re labeled IgG. Results: The number of -SH group per reduced IgG molecule was 2.34. The labeling yield of 99mTc-IgG and 188Re-IgG were 90% and 95%, respectively. The stability of 99mTc-IgG at 1, 4, 6 and 24 hr was 91%, 83%, 78%, 7% and that of 188Re-IgG, high uptake was found on kidney, blood, stomach and abscess (9.42±0.68, 1.43±0.24, 0.86±0.18, 0.72±0.10 %ID/g, respectively). The uptakes at 24 hr were kidney, abscess, stomach, and blood in descending order. In case of 188Re-IgG, high uptake at 4 hr post injectappeared on kidney, blood, abscess and stomach (3.92±0.62, 1.32±0.08, 0.88±0.01, 0.26±0.06, respectively). The upatkes at 24 hr were kidney, abscess, blood abd stomach in descending order. The abscess to blood uptake ratio of 99mTc-IgG was 0.5 at 4 hr and 2.02 at 24 hr and that of 188Re-IgG was 0.67 and 1.29. Conclusion: 99mTc-IgG and 188Re-IgG and 188Re-IgG canbe labeled efficiently with direct labeling method. However, 99mTc-IgG and 188Re-IgG, labeled with direct method, was unstable. Further study in needed to enhance the stability of the antibody labeling.