콜로이드 골드 나노입자의 단백질 수송성 평가법

김미영,노상명,김정목,최한곤,김정애,오유경 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.6

Colloidal gold nanoparticles might be of use as nano scale delivery systems of various therapeutic materials in the firture. Recent studies have reported the feasibility of colloidal gold nanoparticles as gene delivery systems or protein delivery systems. In this study, we aimed to develop a short-step method useful for screening the optimal coating conditions of colloidal gold nanoparticles with proteins. We observed that colloidal gold nanoparticles have properties of changing its unique color when they were exposed to NaCl solution. Taking advantage of the color changing properties of colloidal gold nano-particles, we applied the color testing method of colloidal gold nanoparticles solutions for evaluating the protein coating nature. Using bovine senim albumin as a model protein, we tested the protein coating of colloidal gold nanoparticles via the color change upon NaCl addition. The optimal coating concentration and coating conditions of colloidal gold nanoparticles with bovine serum albumin were fixed using the color testing methods. We suggest that the color testing method might be applied to optimize the coating condition of colloidal gold nanoparticles with other therapeutic proteins.

배달 미니 게임 개발:"최고의 웨이터를 꿈꾸며"

김정훈,정한교,김영옥,김중곤,박정윤,윤진성,김경식 호서대학교 반도체제조장비국산화연구센터 2001 반도체장비학술심포지움 Vol.2001 No.-

본 미니 게임은 웨이터라는 직업을 모티브로 하여서 남녀노소 누구나 재미를 느낌과 동시에 기억력 향상시켜 주는 게임제작이라는 목적아래 제작되었다.본 논문에서는 이 게임의 제작과정을 기술하고자 한다.이 게임은 제3회 AGC(한국 아마추어 게임제작 공모전)에서 우수 작으로 선정되었다.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1997)

김재홍,문득곤,김정수,김용준,임동진,박상훈,김희성,이민수,송기훈,김갑형,김형석,성소영,이인섭,김석우,황지환,조창근,김경문,부태성 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.3

Background : In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. Objective & Methods : For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1997. 99 strains of N. gonorrhoeae were isolated, among which 45(45.5%) were PPNG. Conclusion : The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 45.5% in 1997.

ICP(Inductively Coupled Plasma) 처리에 따른 n-type SiGe/Metal contact의 SBH(Schottky Barrier Height) 연구

김이곤,장호원,전창민,송영주,강진영,심규환,제정호,이종람 대한금속재료학회 2005 대한금속·재료학회지 Vol.43 No.2

The effect of surface treatment of n-type SiGe using the inductively coupled plasma (ICP) was studied by current-voltage and x-ray photoemission spectroscopy measurements. The ICP treatment produced surface oxides and point defects at the surface of SiGe. The x-ray photoemission spectroscopy measurements showed that atomic ratio of Ge/Si was increased after the etching treatment. These results provide the evidence that Si vacancies were produced at the etched surface. Si vacancies acting as donor for electrons resulted in shift of Fermi level to near the conduction band. As a result, Fermi level could be pinned at such Si vacancies, leading to the remarkable reduction of Schottky barrier height and the reduced dependence of Schottky barrier height on metal work function. (Received September 7, 2004)

作業環境 騷音에 對한 考察

김남천,최한영,채수권,손정곤 서울保健大學 1991 論文集 Vol.11 No.1

A Review was performed on occupational noise exposure as follows ; First, Domestic laws and ordinances relative to occupational noise are surveyed, and also a legal action which both employor and employer can be taken to prevent a exposure noise are showed. Second in order to evaluace of occupational noise problems, various noise standards and method have compared with some overseas countries.

거푸집-동바리 시스템의 붕괴현황조사 및 원인분석

김곤묵,김호수,정성진,곽순섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

This study analyzes the defect causes under the investigation of collapse situation in form-shore system through the analysis of design criteria, loading and work conditions. Specifically, these defect causes can be classified as the three cases from the results of the investigation. Those are the external, design and construction defects which are closely related. So, one defect can induce another defect and this can lead to the collapse accident of form-shore system. Therefore, this study presents the improvement method to solve the problems relating to the design process and the actual construction application according to the defect causes.

10주간의 행동요법이 비만 초등학생의 혈중지질 성분에 미치는 영향

김현준,김태운,박태곤,박찬호,예정복 釜山大學校 附設 體育科學硏究所 2003 體育科學硏究所 論文集 Vol.19 No.-

The purpose of this study was to verify the effect of behavioral modification therapy among elementary students by comparing and analysing serum lipid between the experimental group and the control group on obese children. For this study, 44 obese children(boys: above 25% of % fat, girls: above 30% of % fat) between 11 and 12 years old S elementary school in Busan city were engaged in and were divided into two groups, each group consisting twenty two children an experimental group for behavioral modification therapy and a control group without any kind of obesity management program......

다중경로 환경에서 시공간 빔포머를 이용한 시스템의 채널 파라미터 부정합에 대한 성능 평가

김성곤,오정근,변건식 동아대학교 정보기술연구소 2003 情報技術硏究所論文誌 Vol.11 No.1

As a channel of a DS-CDMA system is shared among several users, the receivers face the problem of MAI. Also the bandlimited channel leads to ISI. Both components are undesired, but unlike the additive noise process, which is usually completely unpredictable, their space-time structure helps to estimate and remove them. This paper investigates a DS-CDMA system with a fading multipath channel. The investigations have been separated into a channel estimation part and a reception part. In the estimation part of separated two parts, the multipath parameters such as DOA and TOA are evaluated in this paper. In the part of receiver, we used these parameters and tested the performance of this receiver about space-time beamforrners(Decorrelating, Match-Filter, Wiener-Hopf, Subspace-Based). To assess many different estimation techniques and beamformers, the simulation compared with theoretical values is performed.

우리나라 아파트團地의 問題點 分析 및 造景設計基準에 關한 硏究

金貴坤,任勝彬,曺正松,安建鏞 서울大學校 農科大學 1980 서울대농학연구지 Vol.5 No.2

It has been 22 years since the first apartment was built in Korea. Recently more and more apartments have been being introduced to Korean people and has been changing traditional Korean life style. Residents of apartment complexes in Korea suffer from various problems such as sisregarding of traditional Korean exterior space, pathology, improper community facilities and green spaces, destruction of natural environment, and lack of diversity and chracter in buildings and outdoor spaces. Historically the techniques of residential site design have been developed through three evolutionary steps. The first step was the Garden City idea of Ebenezer Howard in England(1898). In his conceptual plan he located Grand Avenue in the center of residential site. However, the green space was divided by road from residential site. The second step was the Sunnyside Gardens in New York(1924). The city Housing corporation of New York City built apartments with new concept which contained large common green spaces within a block surrounded by apartment buildings. This was possible because the lot subdivision no longer existed. The third step was the Radburn Plan(1929) in New Jersey. This was the second project of the City Housing Corporation. This plan invented two important concepts in residential site design. The one is super block concept which does not permit vehicle road within a large block. The other one is culs-de-sac road of which has a dead end on the one end. These two concepts contribute to making internal common green space without car traffic. With this concept the housing was ideally interwoven with green spaces. The Radburn Plan was the beginning of cluster development in residential site and innovation for moter age. At present, after 50 years from Radburn Plan, the basis concept of it is still valid and useful in residential site design. However, we need to make another evolutionary step for the better quality of living. The situations in Korea are different from those in western countries. Apartment is one of the western-origin housing types. Koreans have to modify western-oriented apartment buildings and site plans for cultural adaptation. Furthermore, we have to create new concepts for the better quality of living. Followings are the propositions for site design of apartment complex in Korea. 1. Cultural Aspect-One of the traditional characters of Korean exterior space os intermediate space between interior and exterior space. In order to provide intermediate space, sequence planning and gradual change of space atmosphere in outdoor space design is needed. 2. Social Aspect-We have to consider life cycle of residents, provide various community activities, increase natural elements, and decrease pathologh in apartment complex. 3. Functional Aspect-Pedestrian was should be separated from vehicle way in any case. Pedestrian way system can be benefited from combining with green space system. Green spaces should have systematic link instead of dispersed disposition without connection. The land use pattern should also have systematic and functional relationship. 4. Ecological Aspect-Dynamic equlibrium in eco-system should be preserved or modified with minimum change during and after development. The elements in inventory should be checked are land slide, erosion, surface and ground water, vegetation, wildlife, micro climate, etc. 5. Perceptional Aspect-Apartment complex should be considered as a group form as well as individual form of buildings. It is recommendable to divide outdoor spaces into human scale and to give diversity to each space and building instead of uniform treatment.

L.-F. CELINE의 작품에 나타난 서술기법에 대한 연구

김정곤 프랑스문화예술학회 2000 프랑스문화예술연구 Vol.2 No.-

La presente etude se propose d'analyser la technique narrative dans les romans de Celine. Il modifie les rapports classiques entre l'auteur et le narrateur, le narrateur et le lecteur. D'abord, la fusion de Celine et ses personnages, la disparition de l'auteur au profit du narrateur provoquent au recit une plus grande neurtralite, au sens etymologique du terme, le 'je' n'est ni l'un ni l'autre. Il en resulte que l'auteur peut etre plus present lui-meme dans le texte, a la fois dans le passe de ses avantures et dans le present de sa narration. Dans les innovation des rapports entre l'auteur et narrateur, Celine elargit la sphere d'activite du narrateur. S'ecartant de la mode narrative traditionnelle, la de narrateur, ches Celine, tient a la complexite dansla mesure ou il n'est pas une personnage 'monophonique', mais le dispositaire de tous les discours. Dans les romans de Celine, les 'vous', du narrataire, sorte de lecture ideale, se trouvent presque aussi nombreux que les 'je' du narrateur. Si l'une des principales fonctions narratives, chez Celine, est de constamment 'chercher' le lecteur, c'est le narrataire qui est la contribution ce travail. L'engagement implique par ces 'vous' interpellent le leteur en tant qu'homme en generale et en tant que destinataire du recit. Parces procedes, Celine impose son projet litteraire a l'attention du lecteur, leur subjectivite etant masquee par le 'nous'.