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      • 폐인산석고의 증기양생용 콘크리트 혼화재로서의 적용성 평가

        안양진,윤성진,문경주,소양섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

        The purpose of this study evaluates possibilities of waste phsphogypsum into concrete by steam curing admixture. The waste phsphogypsum is made use of 4 types by specific gravity distritubt which is simple and physical dry process and 4 forms(CaSO₄ㆍ2H2O, Type β-CaS0₄ㆍ1/2H2O, TypeⅢ-CaS0₄and TypeⅡ-CaS0₂) which is changed to in low temperature. As a result, by specific gravity distritubt all the types of compressive strength is higher than OPC. In Type β-CaS0₄ㆍ1/2H2O and TypeⅢ-CaS0₄cases, these is similar to TypeⅡ-CaS0₂from strength and are great in the effect of strength improvement.

      • 폐인산석고를 혼입한 시멘트 모르타르의 내산성

        안양진,윤성진,문경주,송훈,소양섭 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

        The purpose of this study is to evaluate the acid resistance of cement mortar admixed with waste phosphogypsum by steam curing admixture. Waste Phosphogypsum is a by-product from the phosphoric acid process for manufacturing fertilizers. It consists mainly of CaSO₄·2H₂O and contains some impurities such as P₂O_5, F^(-) and organic substances. The waste phosphogypsums is made use of 4 forms(Dihydrate, β-Hemihydrate, Ⅲ-Anhydrite and Ⅱ-Anhydrite) which were changed to in low temperature of calcination. The mass change and reduction ratio of compressive strength of cement mortar are investigated to evaluate the acid resistance. The specimens of cement mortar were immersed in HCI(5%) and H₂SO₄(5%, 10%) during 14, 28 and 56days. As a result, mass change and reduction ratio of compressive strength of cement mortar admixed with waste phosphogypsum are lower than cement mortar contained OPC alone. Also, Ⅲ-Anhydrite is comparable to Ⅱ-Anhydrite in acid resistance. Therefore, Ⅲ-Anhydrite phosphogypsum calcined at lower temperature could be used as steam curing admixture for concrete 2th production.

      • 공간능력, 시지각 회상 능력, 학습양식에 따른 지구와 달의 운동 개념

        김봉섭,정진우,양일호,정지숙 한국교원대학교 과학교육연구소 1998 청람과학교육연구논총 Vol.8 No.1

        The purpose of this study was to investigate the relationship among spatial ability, learning styles, visual-perception-recall ability, and the conceptual construction of the earth and moon's motion. Four paper-and-pencil tests were used to measure students' cognitive variables. Spatial ability was measured by Spatial Visualization Test, visual-perception-recall ability was measured by Rey's Figure which also have used to test visual-perception-recall ability of right-temporal lobes, and VVT were used to investigate students' learning styles. Further, the test of concept construction was consisted of 15 items about the earth and moon's motion developed by researcher. One hundred and twenty-seven 6th-, one hundred and sixteen 7th-, eighty-seven 9th-grade, ninety-three college students were participated in the investigation of the effects of age and learning style on conceptual construction. In the analysis of students' performances, spatial ability, visual-perception-recall ability, and conceptual achievement showed an increasing pattern with grading. In addition, visual learner's conceptual achievement showed a significantly higher score on conceptual test than verbal learner's(p<0.05). The results of the present study supported the hypothesis that learning styles would differently influence to learning atmospheric concepts by students' learning styles. This study also indicated to be considered the students' spatial ability in learning atmospheric concepts.

      • 폐광미 조립분을 잔골재로 활용한 시멘트 경화체의 특성

        윤성진,문경주,소양섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

        Presently Metal-Mine waste is filled in the revertment, soil dike and undercurrent facilities of waste matter at piles, but this ways are not fundamental method of waste matter and it takes long time to maintain and it spends a lot of money so that we have need of a effective treatment plan and recycling method. In this study, to predict a effective treatment plan of Metal-mine waste(tailing) that is heaped. We observe tailing's physical and chemical basic features. According to examinate a hydration using tailing we evaluate its utilizable possibility as construction materials.

      • 폴리에스테르 모르타르용 충전재로서 금속광산 폐광미의 활용 연구

        윤성진,최낙운,문경주,소양섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

        The purpose of this study is to examine the basic properties of polyester mortars using fine tailing(FT) as a filler. The FT is obtained by centrifugal separation of tailing(TA), and checked for basic properties of shape, particle size distribution, chemical composition, resin absorption. Polyester mortars with FT and ground calcium carbonate(GC) are tested for working life, flexural and compressive strengths. The test results showed that FT has much the same properties as GC in the shape, size and resin absorption. The working life of the polyester mortars is lengthen with an increase in the filter/binder ratio. The polyester mortars with a filter/binder ratio of 1.0 have the maximum flexural and compressive strengths.

      • KCI등재

        정신분열병과 Neurotensin 수용체 유전자 다형성의 연합 연구

        이유상,김형배,한진희,채영규,이정식,이혜순,주연호,김형섭,최인근,양병환 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.6

        연구목적: Neurotensin(NT)은 NT수용체와 결합하여 그 효과를 나타내는 neuromodulator 혹은 neurotransmitter로서 대뇌에서 도파민의 분비를 조절하는데 중요한 역할을 한다. 근래의 연구에 의하면 NT와 그 수용체는 대뇌에서 항정신병 약물의 효과를 매개하는 것으로 생각되고 있으며 약물치료를 받지 않은 정신분열병 환자의 뇌척수액에서 NT의 양이 적으로 보고되고 있어 이들은 정신분열병과 깊은 관련을 가지고 있을 것으로 추정된다. 최근 NT수용체의 유전자의 3`인접영역에서 정보가치가 높은 4 염기반복 다형성이 발견되어 이를 유전 표지자로 하여 정신분열병과의 연합을 알아보았다. 방 법: 서로 혈연관계에 있지 않은 정신분열병 환자 120명(남자 91명, 여자 29명)과 정상 대조군 106명(남자 84명, 여자 22명)을 대상으로 하였다. PANSS를 사용하여 양성 및 음성을 알아보았다. 말초혈액에서 DNA를 분리한 후에 중합효소연쇄반응을 사용하여 3`인접영역에 있는 4 염기 반복 다형성을 증폭하였고 silver staining한 후에 유전자형을 관찰하였다. chi-square 검증과 Bonferroni`s correction을 사용하여 환자군과 정상 대조군간의 대립유전자 빈도의 차이를 알아보았다. 또한 양성 및 음성 환자군으로 나누어 차이를 알아보았다. 결 과: 총 23개의 대립유전자가 관찰되었으며, 399bp의 대립유전자(A10)의 빈도가 환자군보다 정상대조군에서 통계적으로 유의하게 높았다(χ²=16.49, df=1, p<0.001). 음성 정신분열병 환자군과 정상대조군 사이의 비교에서는 정상대조군의 A10의 빈도가 환자군보다 유의하게 높았다(χ²=21.33, df=1, p<0.001). 성별 비교에서 남자 정신분열병 환자군은 대조군에 비하여 A10의 분포가 유의하게 적었다. (χ²=13.71, df=1, p<0.001) 결 론: NT 수용체 유전자와 정신분열병사이에 음성연합이 관찰되었다. NT 수용체 유전자가 일부 정신분열병의 발병과정에서 확실하지는 않지만 어떤 종류의 보호기능을 할 수도 있다는 것을 암시한다. Objectives: Neurotensin(NT), of which functions are evoked by its interaction with neurotensin receptors(NTR), coexists with mesolimbic dopamine and regulates endogenous dopamine release. Recent studies have shown that NT with NTR exerts neuroleptic-like activity within the central nervous system and may play an important role in the pathogenesis and in the treatment of schizophrenia. We have examined the gentic association between schizophrenia and tetranucleotide repeat polymorphism in the 3-flanking region of the NTR gene to investigate the possible contribution of the NTR gene to the schizophrenia susceptibility. Methods: Among 23 alleles identified, the subjects were 120 patients(male 91, female 29)with schizophrenia and 106 normal healthy controls(male 84, female 22). They were unrelated native Korean. PANSS was used to determine positive or negative subgroup in the schizophrenic patients. Using polymerase chain reaction and polyacrylamide gel electrophoresis, tetranucleotide repeat polymorphism(CCTT and CTT) in the 3`-flanking region of NTR gene was observed. For a comparison of NTR gene`s allelic frequencies between patients with schizophrenia and normal healthy controls, chi-square test and Bonferroni`s correction was performed. Results: The frequency of A10 allele(base pair size=399)was significantly higher in normal healthy controls than schizophrenia(χ²=16.4902, df=1, p<.000). In the comparison between schizophrenic patients with negative symptoms and normal controls, the frequency of A10 allele was significantly higher in normal healthy control subjects than patients with schizophrenia(χ²=21.33, df=1, p<0.001). In the case of male, the frequency of A10 allele of schizophrenia was significantly higher than normal controls(χ²=13.71, df=1, p<0.001). Conclusions: NTR gene was negatively associated with schizophrenia. NTR gene`s tetranucleotide repeat polymorphism may provide some protective function against schizophrenia.

      • 안면 비대칭을 동반한 골격성 III급 부정교합 환자의 선수술 치험례

        Jin-Seob Yang(Jin-Seob Yang),Jung-Hoon Kim(Jung-Hoo Kim),Ji-Yeon Lee(Ji-Yeon Lee) 연세대학교 치과대학 두개안면기형연구소 2023 연세임상교정 Vol.30 No.1

        본 증례는 아래턱이 많이 나와서 저작이 힘들어 악교정 수술을 받고 싶다라는 주소로 내원한 19세 여환에 관한 증례보고이다. 심한 골격적 부조화를 나타내는 골격성 III급 부정교합 환자들에게는 악골이나 치조골 분절을 재위치시키는 악교정 수술을 동반한 교정 치료가 필수적이다. 하지만 통상적인 악교정 수술 방식의 경우 술전 교정 과정에서 일시적인 안모의 악화가 일어나며, 이는 환자의 삶의 질과 치료의 만족도에까지 영향을 미친다고 보고되었다. 이에 따라 교정치료에 앞서 악교정 수술을 먼저 시행하는 선수술의 개념이 도입되었다. 그러나 선수술은 통상적인 악교정 수술 방식에 비해 수술 예측도가 떨어지고 수술 교합이 불안정하기에 수술 중에서의 오류가 발생할 수 있고 술후 교합이 설정한 교합과 다르게 형성되는 문제가 생겨 더 심한 재발을 보일 수도 있다. 본 증례는 안면 비대칭을 동반한 골격성 III급 부정교합 환자에서 선수술을 시행하였으나 수술 중 오류로 술후 교합이 예상과 다르게 형성된 환자에서 적절한 술후 교정치료를 통해 안정적인 교합을 형성하였고 심미와 기능의 개선을 얻었기에 이를 보고하고자 한다. In this case report, a 19-year-old patient visited the orthodontic department with a protruded chin and difficulty in mastication as the chief complaints. Orthognathic surgery with orthodontic treatment is essential for patients with skeletal Class III malocclusion and severe skeletal deformities. However, in the conventional orthognathic approach, the facial profile worsens during pre-surgical orthodontic treatment, affecting the patient’s quality of life and satisfaction with the orthodontic treatment. Therefore, the surgery-first approach, which involves performing orthognathic surgery before orthodontic treatment, was introduced. However, the surgery-first approach is less predictable, and post-operative occlusion is more unstable than the conventional orthognathic approach. Therefore, there can be more errors in the surgical procedure, and unstable post-operative occlusion can cause severe relapse. In this case, the patient was treated by the surgery-first approach, but post-operative occlusion was formed differently than simulated due to surgical errors. By performing appropriate post-operative orthodontic treatment, stable occlusion, function, and esthetics could be successfully obtained.

      • Molecular Biological Studies on Korean Garlic Viruses

        Jin Nam Choi,Jong Seob Lee,Yang Do Choi 한국응용생명화학회(구 한국농화학회) 1993 한국응용생명화학회 학술발표회 Vol.1993 No.-

        To understand the molecular structure and pathogenesis mechanism of Korean garlic virus, we isolated several cDNA clones for garlic virus. The nucleotide sequence comparison among the plant viruses reveals that clone 28-9, a GLV cDNA clone, has similarity to the part encoding the replicase of potexviruses, potato virus X (PVX) and narcissus mosaic virus (NMV). The sequence, G--G-GKS, which has been known to be conserved as G----GKS in various ATP- and GTP-binding proteins is fund. To isolate 3`-end cDNA clones for garlic virus, cDNA library was constructed using garlic virus RNA with oligo (dT) primer. The partial nucleotide sequences of 24 cDNA clones were determined and compared with other plant viruses. As a result, several distinct cDNA clones were obtained. Clone V9 has 81.8 % similarity in nucleotide sequence and 93% in deduced amino acid sequence to the coat protein for garlic mosaic virus sequenced in Japan. The coat protein gene constructed into pRSET-A expression vector was expressed in E. coli BL21 and purified by Ni^(2+)·NTA affinity chromatography. Another clone S64 has 82.6% similarity to garlic virus C genes sequenced in Japan. Clone GV2 has repeating sequences, GAATTGAA and GAATTGAATTGAAAACGATTTCGAAAT. Clones J5 and T13 have direct repeat and clone S106 has inverted repeat. To obtain 5`-end cDNA clone for GLV, 5`-extension was carried out using garlic virus RNA with 5`-primer of clone 28-9. GLV cDNA clones were isolated and their nucleotide sequencing is in progress. To understand the pathogenesis mechanism of garlic virus, the method of nucleic acid diagnosis is developing by slot blot analysis.

      • SCOPUSSCIEKCI등재

        골융해와 두개강외 연조직 종괴로 나타난 악성 수막종 : 증례보고 A Cases Report

        양진수,금주섭,이승민,양재영,최천식,주문배 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.7

        Malignant intracranial meningioma is a rare pathologic entity. Although the topic is widely discussed. there is little agreement in the literatures as to the histological and radiological features that warrant the diagnosis of malignant meniugioma. An osteolytic lesion of the skull may have been suggested in several cases. But in adults the most commonly suspected lesion is metastatic lesion ; while meningioma is rarely suspected. Meningiomas are occasionally associated even with extracranial masses. However, most of these masses are firm. and are caused by hyperostosis. Extracranial soft-tissue masses rarely arise in meningiomas, thus, the presence of both osteolytic skull lesion and soft-tissue mass is exceedingly rare in meningiomas. The authors report a case of osteolytic malignant meningioma located at the frontal fossa extending to the subgaleal space appearing as an exracranial soft-tissue mass in a 19-year-old female. The clinical, radiological, neurosurgical, and histopathological features of these lesions are discussed together with a review of the literatures.

      • 가시오가피(Acanthopanax senticosus)의 석유에테르 추출물 중 polyacetylene계 물질의 동정

        양효진,김은미,장규섭 충남대학교 농업과학연구소 2008 농업과학연구 Vol.35 No.1

        This study was conducted to isolate polyacetylenes from the Acanthopanax senticosus and to identify the chemical structure of the polyacetylenes by UV, IR, ¹H-NMR and (13)^C-NMR. One of the liposoluble materials was extracted with petroleum ether. Polyacetylene compounds were collected through solvent fractionation at silica gel column chromatograph. The HPLC was used for the semi-preparative separation IR spectra of fraction 5 showed triple bonds at 2256 cm^(-1) and double bond at 1654cm^(-1), respectively, ¹H-NMR spectra of Fraction 5 showed the double bond at 5.35-5.48 ppm. Triple bond at 64.0. 71.2, 74.2, 80.2 ppm and double bond at 121.89, 133.0 ppm were observed in the (13)^C-NMR spectra. 가시오가피를 실온에서 petroleum ether로 추출한 polyacetylene의 동정하기 위하여 TLC, HPLC, UV spectrum, IR, NMR로 수행하였다. TLC에 전개시킨 결과, polyacetylene 표준품과 동일한 band가 fraction 5에서 확인되었으며, HPLC에서 fraction 5를 분리시킨 결과 retention time이 4.40, 5.36, 6.40분이었다. 이를 UV spectrum에서 확인한 결과, 6.40분의 peak(compound 3)에서 polyacetylenes의 파장인 231.0nm, 239.0nm, 257.0nm을 나타내었다. IR spetrum에서 triple bond 2256cm^(-1)과 double bond1654cm^(-1)의 전형적인 peak를 나타내었으며, (13)^C-NMR(400MHz, CDC1₃)에서 polyacetylenes 전형적인 64.0, 71.2, 74.2, 80.2ppm은 2개의 triple bond에 의한 peak와 121.89, 133.0ppm에서 internal double bond로 결합된 2개의 peak를 확인 할 수 있었다.

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