판막 질환에서의 심근 섬유화 : 심근 조직을 이용한 형태학적 연구 및 혈청 생화학적 지표의 분석

강수진,박덕우,송재관,박경민,송종민,강덕현,한기훈,송현,이재원,주석중,송명근,김정선 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

Pseudomonas aeruginosa와 Acinetobacter baumannii에 대한 Imipenem, Panipenem 및 Meropenem의 시험관내 항균력 비교

송원근,우흥정,강희정,김재석,박민정,이규만 대한화학요법학회 2002 대한화학요법학회지 Vol.20 No.3

목적 : Pseudomonas aeruginosa와 Acinetobacter baumannii는 중요한 병원감염균으로 알려져 있으며 다약제 내성을 잘 유발한다. 최근 들어 전 세계적으로 carbapenem제에 대한 감수성이 떨어지고 있어 문제가 되고 있다. 이에 저자들은 한국에서 분리된 P. aeruginosa와 A. baumannii를 대상으로 imipenem, panipenem 및 meropenem의 항균력을 비교하고자 하였다. 방법 : 150주의 P.aeruginosa (imipenem 감수성, 62주; imipenem 내성. 88주)와 53주의 A.baumannii (imipenem 감수성, 9주; imipenem 내성 44주)를 대상으로 National Committee for Clinical Laboratory Standards의 기준에 따라 미량액체배지희석법으로 imipenem, panipenem. meropenem에 대한 최소억제농도(MIC)를 측정하였다. 결과 : 총 150주의 P. aeruginsa 균주의 MIC_50/MIC_90은 imipenem, panipenem 및 meropenem이 각각 16/64, 16/64 및 4/32㎍/mL이었다, 53주의 A.baumannii 균중의 MIC_50/MIC_90은 imipenem, panipenem 및 meropenem이 각각 32/64, 32/64 및 16/32 ㎍/mL이었다. 88주의 imipenem 내성 P. aeruginosa 균주 중 33주 (38%)는 감수성 결과를 보였으나 그 반대의 결과를 보인 경우는 없었다. 결과 : MIC 결과 상 imipenem에 내성인 P. aeruginosa와 A. baumannii에 대하여 meropenem이 impenem이나 panipenem보다 좀더 강한 활성이 있음을 알 수 있었다. Background : Pseidomonas aeruginosa and Acinetobacter baumannii are important nosocomial pathogens. Many strains are multi-drug resistant, with decreased susceptibility to carbapenem emerging worldwide. We investigated the in vitro activity of imipenem, panipenem, and meropenem against P. aeruginosa and A. baumannii isolates in Korea. Methods : One hundred and fifty strains of P. aeruginosa (imipenem-susceptible, 62strains; imipenem-resistant, 88 strains) and 53 strains of A baumannii (imipenem-susceptible, 9 strains; imipenem-resistant, 44 strains) were examined. Minimal inhibitory concentration (MIC) testing for imipenem, panipenem, and meropenem was performed using the broth microdilution method as described by the National Committee for Clinical Laboratory Standards. Resilts : The MIC_50/MIC_90 of imipenem, panipenem, and meropenem against the clinical isolates were: 16/64, 16/64, and 4/32 ㎍/mL, respectively, against P. aeruginosa; 32/64, 32/64, and 16/32 ㎍/mL against A. baumannii. 33 (38%) of the 88 strains of impenem-resistant P. aeruginosa were susceptible to meropenem but the reverse was observed in none. Conclusion : The MIC data showed that meropenem was more active than imipenem and panipenem against imipenem-resistant P. aeruginosa and A. baumannii isolates.

三角網計算에 있어서 有限要素法의 利用

宋錠根,朱宰佑 順天大學校 1985 論文集 Vol.4 No.1

三角網에서 얻은 角으로서 邊長을 計算한후 그邊長을 利用하여 有限要素法에 의해 三邊綱計算을 行하여 얻은 結果를 要約하면 다음과 같다. 1. 三角測量에서도 그 調整方法으로서 有限要素法을 利用할 수 있다. 2. 有心多角綱計算에 있어서 三角法과 有限要素法에 의한 結果가 相異했는데 이는 첫測線에 한 測點이 이동점이 되었기 때문으로 생각된다. The length of sides was calculated with angles obtained in the triangulation net, and the calculation of the plane trilateration net was performed by the finite element method with the length of sides. The results obtained were as follows: 1. The finite element method can be used for the adjustment of the triangulation net. 2. In the calculation of the triangulation net with a center the results of the two methods were different from each other, because the one point of the first side became the rolling point.

국내의 Acinetobacter baumannii와 Pseudomonas aeruginosa 임상분리주에 대한 Colistin과 Polymyxin B의 감수성 양상

송원근,이태재,박민정,김한성,김재석,우흥정,이규만 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

배경 : 다약제 내성 Acinetobacter baumannii와 Pseudomonas aeruginosa에 의한 감염의 증가로 인해 기존의 치료제를 대신할 수 있는 colistin이나 polymyxin B와 같은 대체 항균제들이 사용되고 있다. 이에 국내에서 분리된 A. baumannii와 P. aeruginosa에 대한 colistin과 polymyxin B의 감수성 현황을 알아보고자 하였다. 재료 및 방법 : 국내 5개 대학병원에서 분리된 균주 중 ceftazidime과 imipenem의 감수성에 따라 93주의 A. baumannii와 99주의 P. aeruginosa를 선택하였다. 액체배지 미량희석법으로 colistin과 polymyxin B의 감수성을 시험하였다. 결과 : Ceftazidime과 imipenem이 감수성인 균주에서는 기타 β-lactam제, aminoglycoside제 및 ciprofloxacin에 대한 감수성율(각각 58-100%, 50-100%, 75-100%)이 높았으나, ceftazidime 또는 imipenem이 내성인 균주에서는 위의 항균제에 대한 감수성율이(각각 ≤31%, ≤47%, ≤18%)이 낮았다(P<0.05). Colistin과 polymyxin B에 대한 A baumannii (MIC_(50/90), 1/2 ㎍/mL)와 P. aeruginosa(MIC_(50/90), 1/1 ㎍/mL)에의 항균 범위는 거의 유사하였고 두 약제 모두 매우 우수한 항균력을 보였다. A. baumannii에서는 1주(1.1%)가 colistin 내성(MIC, 4 ㎍/ mL)이 었으나 polymyxin B에는 감수성(MIC, 2 ㎍/mL)이었으며 이외의 모든 A. baumannii와 P. aeruginosa는 colistin과 polymyxin B에 감수성(MIC, ≤2 ㎍/mL)이었다. 결론 : 국내에서 colistin과 polymyxin B에 둘 다 내성인 A. baumannii나 P. aeruginosa 감염은 없었다. 따라서polymyxin제를 다약제 내성 A. baumannii나 P. aeruginosa 감염에 대한 대체 항균제로 유용하게 사용할 수 있을 것으로 생각된다. Background : The emergence of multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa has become a major problem. The use of nontraditional agents such as colistin and polymyxin B have been tried. The purpose of this study was to evaluate the colistin and polymyxin B susceptibility of A. baumannii and P. aeruginosa isolates in Korea. Materials and Methods : According to susceptibility of ceftazidime and imipenem, selected 93 isolates of A. baumannii and 99 isolates of P. aeruginosa were collected from 5 university hospitals in Korea. Susceptibility to colistin and polymyxin B was tested using the reference broth microdilution method. Results : The rates of other β-lactams, aminoglycosides, and ciprofloxacin susceptibility were high (58-100%, 50-100%, and 75-100%, respectively) in ceftazidime- and imipenem-susceptible isolates but were low (≤31%, ≤47%, and ≤18%, respectively) in ceftazidime- or imipenem-resistant isolates (P<0.05). Colistin and polymyxin B displayed a nearly identical spectrum of activity, exhibiting excellent potency against A. baumannii (MIC_(50/90), 1/2 ㎍/mL) and P. aeruginosa (MIC_(50/90), 1/1 ㎍/mL). Only one of the A. baumannii isolates was resistant to colistin (MIC, 4 ㎍/mL), but the isolate was susceptible to polymyxin B (MIC, 2 ㎍/mL). Conclusion : In Korea, no A. baumannii and P. aeruginosa isolates were resistant to both colistin and polymyxin B. These data suggested that polymyxins may be alternative drugs for multidrug- resistant A. baumannii and P. aeruginosa isolates.

지역사회획득 폐렴의 치료지침 권고안

송재훈,정기석,강문원,김도진,배현주,서지영,심태선,안중현,안철민,우준희,이남용,이동건,이미숙,이상무,이영선,이혁민,정두련,지역사회획득 폐렴 치료지침 제정위원회 대한감염학회 2009 감염과 화학요법 Vol.41 No.3

A successful therapy of community-acquired pneumonia requires appropriate empirical antimicrobial therapy. Etiology and antimicrobial susceptibility of major pathogens of pneumonia can differ by country. Therefore, an ideal treatment guideline of community-acquired pneumonia should be based on the studies performed in each country. We developed a treatment guideline for community-acquired pneumonia in immunocompetent adults in Korea. This guideline was developed by the joint committee of the Korean Society for Chemotherapy, the Korean Society of Infectious Diseases, and the Korean Academy of Tuberculosis and Respiratory diseases.

열처리에 따른 Cd₁-xZnxS/In 박막의 광학적 및 전기적 특성 분석

송우창,이경호,심상흥,이상교,심재선,박종국 三陟大學校 2002 論文集 Vol.35 No.-

In this thesis, effects of the thickness of indium films and the annealing temperature on optical and electrical properties of chemically deposited CdZnS films for the efficiency of the Cd1-xZnxS/CdTesolar cells were investigated. To improve the electrical conductivity of Cd1-xZnxs films, thin indium films(10-4Onm thickness)were evaporated on the suface of Cd1-rZnxs films. Experimental parameters such as indium film thickness, Zn mole fraction, and the annealing temperature in terms of structural and electrical properties of Cd1-xZnxs films were investigated. The diffusion process was carried out by heating the sample in air at 150-550℃ for 20 minute As the indium film thickness is increased, the resistivity decreases and the lowest value(0.3 O -cm)is obtained for Cd1-xZnxs films annealed at 450℃ with 40nm of the thickness.

신라시대 화랑도에 나타나는 상무정신과 일본 무사도(Bushido)의 기원에 관한 연구

송일훈,김재우 한국스포츠리서치 2005 한국 스포츠 리서치 Vol.16 No.2

This Study Is Aim to Demonstrate The Origin of 'Sangmu Spirit' from 'Silla Hwarangdo' and 'Bushido' of Japan. In This Study, In This Study, We Can Find Some Important Results. At First, Japanese 'Bushido Spirit' Came Over 'Silla Hwarangdo's Sangmu Sprit'. Second. 'Bushido's Father Minamoto Family' Came from 'Silla'. Third. The Word 'Bushido' Is Derived From Korean 'Musa'. Fourth, 'Silla Hwarang' Training The Spirit of Chivalry for Their Fatherland. Fifth, 'Silla Sangmu Sprit' Is The Basic Ideas of Japanese 'Bushido'. It Is The Same as 'Silla Hwarangdo'. In Conclusion, We Can Find That Japanese Bushido's Origin Is 'Silla Hwarangdo Sangmu Spirit'. Moreover 'Bushido's Father Minamoto Family' Is Came from 'Silla'. Finally. Korea and Japan Must Make Scientific Mutual Assistance. 'Sangmu Spirit' and 'Bushido' Is Korean and Japanese Important Cultual Assets That We Ought to Succeed and Develope.

박막 인덕터와 제조와 DC-DC Converter에의 적용

오영우,민복기,송재성 경남대학교 신소재연구소 1999 論文集 Vol.11 No.-

Thin film inductors of 10 mm×10 mm with inner coil type of 5 turns were fabricated by sputtering, photo-masking, and etching processes. The inductor has an inductance of 585 nH at 1MHz. And to estimate the applicability of the thin film inductors fabricated in this research to DC-DC converters. the test board of DC-DC converters was made. It was a boost type and input voltage of 2.7 to 5 volts. output voltage of 5 volts, and the switching frequency was 1.6 MHz. When the thin film inductor was adopted, the converter was operated normally. and the maximum efficiency was 49 % at the load of 50.5 Ω and the output power was 0.51 W. This result was not satisfactory for practical usage at present, but the switching FET devices for higher frequency use be developed in the near future, and then more higher frequency switching DC-DC converter will adopt these inductors.

스파이럴형 박막 공심 인덕터의 제조와 특성

오영우,김현식,송재성 경남대학교 신소재연구소 1997 論文集 Vol.8 No.-

마이크로 자기소자중 가장 간단한 형태인 스파이럴형 박막 공심 인덕터의 제작 및 특성 평가에 관해 연구하였다. 간단한 습식 식각공정으로 두께 12μm, 폭 수십 μm 정도의 코일 패턴을 제작할 수 있었으며, 양호한 미세 패턴을 얻었고, 마이크로 스트립 선로로 제작한 측정 zig로 비교적 정확한 특성을 측정할 수 있었다. 또한, 크기가 10×10mm, 선폭 300μm, 선 간격 70μm, 턴수 12인 스파이럴 코일형 공심 인덕터의 공진 주파수는 300MHz였고, 성능지수는 4 이었다. Recently the development of electronic machine industries have been miniature of size as well as increasement of driving frequency in electronic parts. In this study, we fabricated thin film inductors by using thin films manufacturing techniques such as photolithograghy and wet etching process, and the properties of these devices are measured at high frequency range of 1 MHz∼1 GHz. The accurate measuring technique by using network analyzer system having microstrip line was established. The inductors are fabricated with several ten micrometers by means of wet etching process known as easier and more economic than dry etching process. The properties of spiral-type thin film air core inductors with Wc = 300μm, dc = 70μm, number of turns = 10. and t_{cu} = 12μm were found to have Q of 4. L of 50nH at 300MHz and f_{R} of 300MHz.

전자부품의 형상인식 및 제어

이우송,Nguyen Van Quyet,오세봉,조창제,한성현 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

The purpose of this research is to develop the character recognition technology based on pattern recognition for non-contacting inspection optical lens slant or precision parts, and including external form state of lens or electronic parts for the performance verification, this development can achieve badness finding. And, establish to existing reflex data because inputting surface badness degree of scratch's standard specification condition directly, and error designed to distinguish from product more than schedule error to badness product by normalcy product within schedule extent after calculate the error comparing actuality measurement reflex data and standard reflex data mutually. Developed system to smallest 1 pixel unit though measuring is possible 1 pixel as 37㎛×37㎛ (0.1369×10-4㎟) the accuracy to 1.5× 10-4㎜ minutely measuring is possible performance verification and trust ability through an experiment prove.