뇌졸중 후 중추성 통증 환자에 대한 동서협진이 진통과 재활에 미치는 영향

이현종,김수영,이상훈,서동민,이두익,김건식,이재동,이윤호,양형인,박재경,최도영 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

Purpose : In order to study the effectiveness of East-West pain treatment on central poststroke pain(CPSP), we evaluated its effect on alleviation of pain and rehabilitation of CPSP Patients who were treated with electroacupuncture and west pain treatment for four weeks. Methods : Twenty four patients diagnosed by their pain characteristics of central pain from stroke were treated with sympathetic nerve block, gabapentin, amitriptyline, and electroacupuncture for four weeks. Pain intensity through the visual analogue scale(VAS), and improvements of mobility and rehabilitation through the modified Barthel index(MBI) and Rankin scale(RS), respectively, before and after pain treatment were also assessed. Results : VAS pain scores were significantly improved from 7.7±1.7 to 4.4±2.0 with pain treatment(p<0.05). In accordance with improvement of pain scores, RS and MBI scores were also improved from 2.88±0.95 to 2.13± 1.01 and from 83.0± 16.9 to 94.7±9.5(p<0.05), respectively, with pain treatment(p<0.05). Conclusions : It was suggested that the active pain treatment was contributed to the rehabilitation of CPSP patients, resulting in improvement of quality of life of CPSP patients. Futhermore, East pain treatment in combination with West pain treatment may be useful modality to alleviate CPSP.

지난 2년간의 학회지 "신경정신의학" 심사 평가보고

김찬형,김세주,김도관,김성곤,박원명,송동호,박용천,이영문,오강섭,정영철,이상열,김주한,이동영,이헌정,함병주,김율리,김문두,김정진,이강욱,천근아,김재진,홍진표,홍승철 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

추황배(Pyrus pyrifolia Nakai cv. Chuhwangbae) 과피로부터 1종의 Sterol과 3종의 배당체 화합물의 단리·동정

이유건(Yu Geon Lee1),조정용(Jeong-Yong Cho),이현주(Hyun Joo Lee),이용현(Yong Hyun Lee),이상현(Sang-Hyun Lee),한태호(Tae-Ho Han),김월수(Wol-Soo Kim),박근형(Keun-Hyung Park),문제학(Jae-Hak Moon) 한국식품과학회 2013 한국식품과학회지 Vol.45 No.5

본 연구에서는 배의 유용성 증명을 위한 일환으로 배의 화학성분을 분자수준에서 밝히고자 하였다. 이에 배 과피 MeOH 추출물을 용매분획하여 얻은 EtOAc-산성 분획과 EtOAc-중성분획을 대상으로 Sephadex LH-20, silica gel, 그리고 ODS colmn chromatography와 HPLC를 이용하여 정제 및 단리하였다. 그 결과, EtOAc-산성 분획과 EtOAc-중성 분획으로부터 각각 2종씩의 화합물을 단리하였다. 단리된 화합물 1-4는 1H- 및 13C-NMR 분석을 통하여 각각 (S)-(+)-2-cis-abscisic acid O-β-D-glucopyranosyl ester (화합물 1), 1-[4-O-β-D-glucopyranosyl]phenyl ethanone(piceoside, 화합물 2), β-sitosterol (화합물 3), 그리고 β-sitosteryl 3-O-β-D-glucopyranoside (화합물 4)로 동정되었다. 단리된 3종의 배당체 화합물(화합물 1, 2, 4)들은 본 연구에 의해 배로부터 처음 동정되었으며, 화합물 3은 추황배로부터 처음 동정되었다. 본 연구결과가 배 함유 성분연구는 물론 배의 기능성 해명 연구에도 추후 중요한 기초자료로 활용되길 기대한다. We isolated and identified antioxidants from acidic and neutral ethyl acetate fractions of the peel of pear (Pyrus pyrifolia N. cv. Chuhwangbae). We isolated 4 compounds from the methanol extract, by using 3 different types of column chromatography (Sephadex LH-20, silica gel, and octadecylsilane) and preparative HPLC. We identified the isolated compounds as (S)-(+)-2-cis-abscisic acid O-β-D-glucopyranosyl ester (compound 1), 1-[4-O-β-D-glucopyranosyl]phenyl ethanone (picroside, compound 2), β-sitosterol (compound 3), and β-sitosteryl 3-O-β-D-glucopyranoside (compound 4) by nuclear magnetic resonance analysis. We are the first to report the identification of compounds 1, 2, and 4 from pear.

중심 정맥 삽관법에 의한 동정맥루: 증례 및 문헌 고찰

이 근,원형섭,양기창,박철완,김상일,정호성,이종호 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

A 36-year old woman with end stage renal failure and hypertension was transferred from a university hospital to our emergency department due to a enlarging right cervical mass associated with a palpable thrill and a bruit. Over a 2 month period, she required hemodialysis for severe azotemia at a university hospital in Seoul. 3 days after a difficult attempt at a internal jugular cannulation, she developed a progressive swelling in the right lower cervical area. An arch and primary branch arteriogram revealed a arteriovenous fistula between right innominate artery and internal jugular vein with a large intervening pseudoaneurysm. She underwent vascular surgery within 1 week of injury and subsequent postoperative angiogram showed complete resolution of the fistula. This rare condition is reported with a review of the literature.

정보시스템 서비스의 종합적 품질평가모형에 관한 연구

이명호,윤재욱,이경근 한국경영과학회 1999 한국경영과학회지 Vol.24 No.3

Recently, information technology and information system(IS) are rapidly diffused throughout the world. In the global competitive environment, the success of IS becomes the important on e among the critical success factors(CSF) of the firm. For achieving it, the firm must continually involve itself in the quality evaluation and improvement of IS. The quality concept was changed into the customer-oriented quality one. There is no exception to the quality of IS. In the past, IS quality was determined by the IS developer or IS department offering service. Now it is evaluated by the user of IS service, and then the customer-oriented user satisfaction becomes an important issue. The purpose of this study is to develope the total quality evaluation model of IS through TQM approach First, all success factors of the domestic IS are extracted from the foreign and domestic literatures of IS success factors contained the technical and behavioral aspects. And the extracted factors are classified with evaluation levels for quality evaluation and developed into a total quality evaluation model. Finally the model usefulness is analyzed.

수 종의 생약제제가 human fetal osteoblasts의 염기성 인산분해 효소 활성에 미치는 영향

이명구,유형근 원광대학교 치의학연구소 2003 圓光齒醫學 Vol.12 No.2

Several growth factors and polypeptides are not commonly yet used for regenerators of bone tissue or alveolar bone because of the insufficiency of studies on their side effects, genetic engineering for mass production and stability for clinical application. Recently, many herbal medicines, which have advantage of less side effects and possibility of ling-term use, have been studied for their capacity and effects of anti-bacterial, anti-inflammatory and regenerative potential of periodontal tissues. Morindae Radix, Cibotium Barometz (L.), Albizziae Cortex, Cistandhis Herba have been traditionally used as medicines for treatment of bone disease in Eastern medicine. The objective of the present study is to examine the ability of alkaline phosphatase (ALP) activity of human fetal osteoblast (hFOB1) when several natural medicines were supplemented. hFOB1 were cultured with Dulbecuo's Modified Eagle's Medium Nutrient Mixture F-12 HAM ( DMEM/F-12 1:1 Mixture, Sigma, USA) and negative control, dexamethasone (positive control), and each natural medicines for 3 days. And then ALP activity was measured by spectrophotometer for enzyme activity and Alizarin red S staining for morphometry. Among the natural medicines of this study, Morindae Radix, Cibotium Barometz (L.) and Cistanchis Herba induced higher activity of ALP systhesis than negative controls in all experimental group. Albizziae Cortex showed mild increases than negative control group. According to measurement of positively stained area, all of the natural medicines of this study increased compared to negative control. Especially, Cibotium Barometz (L.) and Cistanchis Herba showed statistical significance compared to negative control (p<0.05). These results indicate that Morindae Radix, Cibotium Barometz (L.), Albizziae Cortex, Cistandhis Herba have an inducing ability of ALP synthesis on osteoblast.

복합적인 레지스트 패턴 붕괴현장의 역학적 해석

이형주,박준택,안일신,김옥근,오혜근 한양대학교 이학기술연구소 2003 이학기술연구지 Vol.6 No.-

패턴의 선폭이 100nm이하로 작아짐에 따라 패턴이 부러지고, 휘고, 떨어져 나가는 현상이 발생하는데 이러한 현상을 패턴 붕괴 현상이라고 하며, 반도체 생산과 수율에 많은 영향을 미친다. 패턴 붕괴 현상은 리소그래피 과정 중 현상 후 세척액을 건조하는 과정에서 주로 발생하며 세척액의 표면장력에 의한 모세관 현상이 주된 원인으로 알려져 있다. 패턴 붕괴 현상을 시뮬레이션하기 위하여 패턴이 세척액에 의해서 균일한 압력을 받을 때와 집중 압력을 받을 때의 역학적 모델을 세우기 각각의 모델을 통하여 선폭과 패턴간의 거리에 따른 임계 높이/선폭비 (aspect ratio) 를 계산하여 실제 실험 결과와 일치하는 모델을 선정하였다. 또한 패턴 내부에 생기는 stress 에 의한 부러짐 현상과 패턴 과 레지스트 패턴 하부 층 사이의 접착력 부족으로 발생하는 떨어짐 현상을 해석하였다. High aspect ratio resist patterns with dimensions below 100 nm often bend, break or tear. These phenomena are generically called "resist pattern collapse". Pattern collapse is a very serious problem in fine patterning of less than 100 nm critical dimension (CD), so that it decreases the yield. In order to mechanically analyze this phenomenon and create its simulator, two models have been made and compared. In this paper, various approaches with various analyses are made to understand pattern collapse. Also, the critical aspect ratio for 100 nm node, that determines whether pattern collapse happens or not, can be calculated with these approaches. Finally, tear type caused by insufficiency of adhesion strength between the substrate and the resist is analyzed with a point of view of the surface free energy.

빅 스포츠 이벤트(월드컵) 개최와 스포츠관광 발전방안

이근모,이재형,김찬룡 釜山大學校 附設 體育科學硏究所 2001 體育科學硏究所 論文集 Vol.17 No.-

The purpose of this study is to provide ways of developing sport tourism by Investigating the trends, previous studies and theoretical background of the tourism and economic effects of big sport events, with reference to related previous literature, journals, reports, materials related to sport tourism and survey results published by Korea National Statistical Office. The Following is the conclusion suggested based on results of the study. First, participation by people of the community needs to be promoted. Especially, big sport events require systems that make possible active participation and support by people of the community. Those systems may include means of forming and collecting opinions such as open briefing, public hearings and seminars, organizations for management or consultation whose member include representative of the community, and volunteering service systems as established and strengthened as can be seen in foreign countries. Second, pre-and post evaluation system should be introduced. Like in other events big sport events have their own final and process purposes. The latter is related to the way of forming and managing sport event organizations, while the former is about ultimate results pursued by sport event. The better accomplishment of the final purpose requires understanding how sport event. The better accomplishment of the final purpose requires understanding how sport events incorporate aspects of tourism. The understanding can be made through evaluation effects of sport events before, during and after the events. Third, whether criteria of the purpose accomplishment of sport events are fulfilled can be determined through the financial analysis and economic efficiency evaluation of the events, the investigation of thoughts and attitudes by people of the community, the examination of perceptions and types of tourists and the evaluation of economic effects of those events. These processes need to be performed with consistency before, during and after sport events. Fourth, products of sport tourism need to bo developed continuously. Big sport events may attract a great attention from mass media around the world by using a variety of tourist information strategies including cultual events celebrating the ground-breaking, construction or opening of port stadiums, pam tours inviting foreign reporters and journalists which I turn lead to the production of relevant, appealing special shows, and programs showing real tastes of Korean culture. Supportive events related to Korean traditional musics, dances, martial arts, foods, pure arts and literature should be also provided to raise the atmosphere and images of sport event as well as inform this nation's history and culture. Firth, sport tourism marketing should be strengthened. Generally sports and tourism have been treated separately. But it is mow recognized that the two parts are closely correlated. such correlation between sports and tourism should be more developed. on which relevant marketing business need to be promoted.

식물성 기름의 단독 및 혼합이 도우넛 튀김유로서의 특성에 미치는 영향

李根保,金亨烈 瑞逸專門大學 1991 論文集 Vol.9 No.-

시판 옥배유, 면실유, 대두유 및 미강유를 각각 단독 및 2~4종 혼합한 혼합유를 도우넛 튀김용 기름으로 사용하여 185±2℃에서 5시간동안 가열하면서 매 시간별로 도우넛을 튀긴 다음 이 도우넛으로부터 기름성분을 추출하여 본 연구의 시료유로 하였다. 이 시료유들의 산값, 과산화물값, Lovibond color, 발연점 및 AOM 안정성을 측정하여 다음과 같은 결론을 얻었다. 즉, 도우넛 튀김유로서는 면실유와 미강유가 우수하였고, 옥배유와 대두유는 부적당하였다. 이러한 결과들로 볼 때 도우넛 튀김용 기름으로는 면실유-미강유, 옥배유-면실유-미강유 및 옥배유-면실유-대두유-미강유의 혼합유계가 가장 적합하였다. Frying oils for doughnut, used for the investigation, were domestic corn germ, cottonseed, soybean and rice bran oil as well as all sorts of blented oils. Blending ratio of constituent oils for manufacturing of sample blended oils was same amount(v/v). Sample oils in this investigation are obtained by solvent extraction used for diethyl ether from doughnut samples. At thisn time, doughnuts are fried during 5 hours at 185±2℃, which is carried out 1 hour unit. We are obtained as followed result from changes of acid and peroxide value, Lovibond color, smoke point AOM stability of these sample oils. That is to say, frying stability was increased to the blending oils, cottonseed and rice bran oil were suitable but soybean and corn germ oil were not suitable as base oil of blended oil in oder to frying of doughnut. From these results, frying oil of doughnut was most suitable blended oils, which is cottonseed oil-rice bran oil, corn germ oil-cottonseed oil-rice bran oil and corn germ oil-cottonseed oil-soybean oil-rice bran oil etc.

표면 SH파 모드의 분산특성 해석과 그 응용

이상용,박익근,윤종학,노승남,안형근 한국공작기계학회 2001 한국공작기계학회 춘계학술대회논문집 Vol.2001 No.-

A new flaw detection technique using by SH angle beam method has been discussed. The SH-wave is horizontally polarized shear wave and the surface SH wave has a characteristic of traveling along near surface layer. The surface SH wave technique is valuable for the detection of fatigue cracks at fillet weld heels which cannot be detected by other ultrasonic technique such as angle beam technique and The dispersion curves of it has simple characterization. In this work, using these beneficial chraterization, quality evaluation of spot weld with ultrasonic sound intensity of SH-wave passing through nugget area of spot weld are verified experimentally.