회맹장 및 대장을 침범한 장 결핵에 있어서 바륨을 이용한 방사선 이중조영촬영 소견에 대한 연구

진용현,전혜정,이용근,강철호,조성범,김윤환,박철민,차상훈,김일영,이혜경 건국대학교 의과학연구소 2002 건국의과학학술지 Vol.12 No.-

To determine the characteristic double contrast barium enema findings of ileo-cecal and colonic tuberculosis and to make differential diagnosis from other bowel inflammatory disease. Sixty-seven patients confirmed as ileo-cecal and/or colonic-tuberculosis in six hospitals were evaluated retrospectively. The diagnosis was proven by endoscopic biopsy, surgery, and clinical follow up. Nine of 67 patients were excluded because radiologic findings were normal though endocopic biopsy examinations resulted in tuberculosis. Histopathological diagnosis were madein 58 cases as follows: endoscopic biopsy(n=29), operation(n=12), follow up examination(n=14), tissue culture(n=1), laparoscopic biopsy(n=2). There were 30 men and 28 females. The mean age were 36 yrs(range:16-67), 34 patients were in the second and third decade. The distribution of lesions, morphological characteristics, mucosal changes, ulcer shape and depth, associated with other tuberculous lesion, multiplicity were retrospectively analyzed in the findngs of double contrast barim enema. The commonest clinical symptoms were abdominal pain(n=35, 60%) and diarrhea(n=18, 31%). The chest radiography revealed association of pulmonary tuberculosis in 39 cases. Tuberculous lesions of other organs except chest were present in five cases. Double contrast barium enema findings showed a thickening and irregularity of intestinal mucosal fold(n=29, 50%), bowel contraction and/or shortening(n=26, 45%). There were small, nodular, superficial ulcers in the case of ulcer depth less than 2 mm in the depth. As many as 39 cases(67%) in this series had two or more lesions in the intestinal tuberculosis. The involved segment revealed symmetrical feature(n=21, 36%). Inflammatory pseudopolypoid lesions were noted in 30 cases(52%). The ileo-cecal region was involved in 38 cases(66%). The ascending colon(n=25, 43%) was the second commonest site with or without contiguous cecal involvement. Lesions in terminal ileum, ileo-cecal valve, transverse colon, descending colon and appendix were seen in 19, 18, 18, 12 and seven cases, respectively. Among 18 cases of ileo-cecal valve lesions, there were incompetency in nine cases(16%) and wide gapping in four cases(7%). In 14 cases, tuberculous enterocolitis was diagnosed by clinical follow-up and double contrast barium enema study. 12 out of 14 cases, the findings of double contrast barium enema of tuberculous enterocolitis were normalized after anti-tuberculous medication. However, two cases showed more aggravated state than before due to inappropriate treatment. Double contrast barium enema plays an important role in the diagnosis of tuberculous enterocolitis, determines the type, site and extent of the involvement and helps in treatment guide by using sequential studies.

약물 유해반응 보고지침 -임상시험의 안전성에 관한 정보 관리지침 -

지동현,김훈교,배진우,손동렬,김인범,전용관,박혜연 大韓臨床藥理學會 1998 臨床藥理學會誌 Vol.6 No.2

유방암의 위와 대장전이

유현아,김은영,서민지,정은,조민정,오현진,장지혜,박지찬,이정의,박석영 이화여자대학교 의과학연구소 2014 EMJ (Ewha medical journal) Vol.37 No.2

Gastric metastasis from breast cancer is rare and only six cases have been reported in Korea. Colon metastasis is more rare than gastric metastasis. We report a 63-year-old woman with gastric and colon metastases of invasive lobular carcinoma of breast. She was diagnosed as right breast cancer, received right modified radical mastectomy 10 years ago and has been treated with chemotherapy and hormone therapy. Investigating for melena and a small caliber of stool, we found gastric and colon metastases. The diagnosis of metastatic breast cancer was made through gross pathologic and immunohistochemistry staining. We report a case with gastric and colon metastases from breast cancer and a review of the associated six case reports in Korea.

다운 증후군과 동반된 그레이브스병 1예

노혜정,신진호,김하영,김용성,백승훈,박병현,조정구 圓光大學校 醫科學硏究所 2005 圓光醫科學 Vol.20 No.1

벼 엽록체 small HSP의 과발현에 의한 형질전환 식물체의 내열성 증가

원성혜,조진기,이병현 Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

To investigate the function of chloroplast small heat shock protein (HSP), transgenic tobacco plants (Nicotiana tabacum L, cv. SR-1) that constitutively overexpress the rice chloroplast small HSP (Oshsp26) were generated. Effects of constitutive expression of the Oshsp26 on thermotolerance were investigated with the chlorophyll fluorescence. After 5-min incubation of leaf discs at high temperatures, an increase in the Fo level, indication of separation of LHCII from PSII, was mitigated by constitutive expression of the chloroplast small HSP. When tobacco plantlets grown in Petri dishes were incubated at 52℃ for 45 min and subsequently incubated at 25℃, leaf color of wild-type plant became gradually white and all plantlets were finally died. Under the conditions in which all the wild-type plants died, more than 80% of the transformants remained green and survived. It was also found that the levels of Oshsp26 protein accumulated in transgenic plants were correlated with the degree of thermotolerance. These results suggest that the chloroplast small HSP plays an important role in protecting photosynthetic machinery, as a results, increases thermotolerance of whole plant during heat stress.

벼 Small HSP의 발현에 의한 대장균의 고온 stress 하에서의 내성의 증가

이병현,이효신,원성혜,조진기 경북대학교 농업과학기술연구소 1999 慶北大農學誌 Vol.17 No.-

This study was conducted to detect the allelopathic effect of water and ethanol extracts from 4 plant species (Lactuca sativa L., Ambrosia elatior L., Oenothenra odorata Jasp., Ginkgo biloba L.) on germination and growth of lettuce seeds. A little bit higher inhibitory effect was obtained in ethanol extracts rather than water extracts. Allelopathic effects varied in the source of extracts and concentrations of 4 plant species and the highest allelopathic effect appeared in 10% solution, regardless of plant species.

참외 흰가루병에 대한 살균제의 예방 및 치료효과 검정

장태현,류연주,임혜정,임수진,최미영,정병룡,김철웅,이용세 한국환경농학회 2006 한국환경농학회지 Vol.25 No.1

창조적 지식 기반 사회를 대비한 국어과 교육의 목표와 내용

정혜승,노명완,옥현진 이화여자대학교 교육과학연구소 2000 교육과학연구 Vol.31 No.1

본고는 창조적 지식 기반사회에서 가장 중요한 국어과 교육의 목표는 언어 사용 기능의 신장이며, 이를 실현시키기 위한 교육 내용에 대해 논의하였다. 일부 국어교육학계에서 기능은 하찮고 저열한 것으로 인식되기도 하였으나, 이는 지식의 개념을 명제적 지식에 국한하여 생각하고 기능을 지식과 별개의 것으로 잘못 인식한 데서 기인한 것이다. 본고는 명제적 지식과 방법적 지식의 관계를 탐구하여 기능 학습에 관한 이론을 두 가지로 정리하였다. 하나는 명제적 지식을 우선하여 이를 연습하고 내재화하는 가운데 기능 학습이 이루어진다고 보는 것이며, 다른 하나는 명제적 지식을 전제하지 않고 다양한 경험과 활동을 통해 기능 학습이 이루어진다는 것이다. 전자는 학습 활동이 용이하고 체계적이라는 점에서, 후자는 앎의 과정을 보다 중시한다는 점에서 장점을 갖고 있으나, 한 편으로 전자는 명제적 지식의 성격이 기능 학습에 유효한 것이어야 한다는 검과, 후자는 실제 수업이 이루어지기 위해서 치밀한 계획과 준비가 필요하다는 점에서 문제점도 안고있었다. 3차 국어과 교육과정은 후자의 방법을, 6차와 7차 국어과 교육과정은 전자와 같은 인식을 보이고 있으나, 논의가 개념 수준에서 이루어져 언어 사용 기능 교육이 제대로 이루어지기 어렵다는 한계를 갖는다. 따라서 국어과 교육의 논의는 개념 수준에서 벗어나 실시간과 실공간 속에서 학생들이 무엇을 어떻게 배울 것인지를 구체적으로 제시하는, 곧 수업화ㆍ자료화하는 실질적이고도 기술적인(technical) 논의로 바뀌어야 한다고 본다. Aim and Content of Korean Language Education for a Society Based on Creative Knowledge This thesis argues the improvement of language use skill that is the most important aim of Korean language education in a society based on creative knowledge and the education contents to achieve it. Some Korean language educators regard skill as worthlessness and vulgarity. However it results from the misunderstanding that the concept of knowledge is limited to knowing that and that skill is entirely different from knowledge. This paper summarizes the theory on skill study in two ways by researching the relations between knowing that and Know-how. One is that skill study is done in the process of exercising and internalizing knowing that preferentially and the other is that it's done through a lot of experiences and actives without any premise of knowing that. These have respective merits : former has the easiness and systematic of skill study and the latter thinks highly of the processing of knowledge. On the contrary, there are problems : in case of the former, the content of knowing that should be effective to skill study and the latter needs accurate plan and preparation for actual study. The 3rd education course in Korean language with latter method and the 6th and 7th without former on place a limit that the argument only in concept level makes the actual language use skill difficult. Therefore the argument of Korean language education should be changed to actual and technical one to present in detail what and how students learn in real time and real space.

반복적인 급성 신부전을 유발한 호산구성 장염 1 예

정혜진;김현태;김유선;정현걸;강윤경;문정섭 인제대학교 2011 仁濟醫學 Vol.32 No.-

Eosinophilic gastroenteritis is a rare disorder of unknown etiology characterized by presence of gastrointestinal symptoms, eosinophilic infiltratio n of one or more parts of gastrointestinal tract without involvement of other organs and absence of parasitic infestation. The clinical presentation depends on the extents and depths of eosinophilic infiltration. Mucosal involvement may result in abdominal pain, nausea, vomiting, diarrhea and weight loss. We report a case of eosinophilic enterocolitis in a 55-year-old female presented with abdominal pain and watery diarrhea resulting in recurrent acute renal failure.

한국산 배의 Polyphenol 화합물군이 쥐의 면역기능에 미치는 영향

최희진,한호석,박정혜,배종호,우희섭,안봉전,배만종,김현구,최청 한국식생활문화학회 2003 韓國食生活文化學會誌 Vol.18 No.4

This study was conducted to investigate immunofunctional activity of the polyphenol fractions isolated from Korean pear. In the experimental of Rosette forming cell, the results showed that all the polyphenol fractions enhance the cell count compared with the control group. Especially polyphenol fraction II and III showed highly significant effect on Rosette forming cell, and allergy inhibition. After antigen challenge, histamine content of blood of the polyphenol groups was lowered to near the normal group.