가족인형놀이가 정신지체 아동의 자발적 발화에 미치는 효과 : 사례연구 Case Study

김윤선,김수정,이경희,한현민 대진대학교 교육대학원 교육연구소 2002 교육연구 Vol.4 No.1

The experiment was undertaken to determine the effect of family puppet play on spontaneous utterance of a five-year-old child with mental retardation. The intervention was three major activites, that is the meeting with father, the playing with elder brother, and the eating time with mother. The intervention continued over 15 weeks, and lasted 26 sessions (20 minutes a session). The data gathered were response to imitation demand, spontaneous imitation, spontaneous utterance, and emotion expressive utterance. The results revealed that in initial sessions response to imitation demand and spontaneous imitation were dominated, but spontaneous utterance and emotion expressive utterance were rapidly increased after 10th and 12th session, respectively.

腦囊尾蟲症의 化學的療法에 관한 臨床的 硏究

朴昌潤,朱炅煥,林漢鍾 고려대학교 의과대학 1982 고려대 의대 잡지 Vol.19 No.3

The purpose of this study was to evaluate the therapeutic effect of praziquantel (Embay8440, Biltricide®) on human cerebral cysticercosis. The praziquantel is a broad spectrum anthelmintic agent and has a high activity against cestodes and trematodes. Before and after the treatment with oral administration of the praziquantel the changes in structure of Cysticercus cellulosae biopsied in subcutaneous tissue were studied by scanning and transmission electron microscope, and cerebral cysticercosis by computerized tomographic scanning. The results were as follows : 1. The findings of the observations on subcutaneous Cysticercus biopsied after treatment were compared with those of before treatment. At the early stage of the treatment, small vacuoles were scattered along the basement layer in the tegumental syncytium of the scolex and neck regions. In the scanning electron microscopic observation, marked surface changes were present in the neck region with many bleb-like structures formed by the bursting of the large vacuoles in the tegumental syncytium. In the specimens biopsied at 2 or 5 weeks after treatment, the degenerations and necrosis of the tegumental syncytium were seen in all part of cysticercus. 2. The scanning electron microscopic findings of Cysticercus cellulosae obtained from the 4th ventricle of the cerebral cysticercosis patients by the surgical operation were identical with those of subcutaneous tissues. 3. In 12 cases of cerebral cysticercosis treated with prziquantel in dosage of 3×25 ㎎/㎏ for 3 or 4 consecutive days, there were no cessations of the convulsive seizures during the 6 months follow up. Among them 9 cases were given again with the same doses of the drug for 4 or 7 days. In 7 of 9 cases, no more convulsive seizure was experienced over one or two years after the second treatment. At the same time the lesions of the brain C.T. scanning were disappeared, decreased in size or calcified. In the other 3 cerebral cysticercosis cases, the complete cure was also obtained after the oral medication of praziquantel with the doses of 3×25 ㎎/㎏ for 7 consecutive days. 4. In the treatment of cerebral cysticercosis with praziquantel, it was found that the combined oral medication of dexamethasone during the course of treatment was effective on preventing and minimizing the side effects.

혼합형 자가면역성용혈성빈혈과 동반된 Evans 증후군 1례

선길홍,윤찬영,박상곤,박경희,우정주,한경택,김진화,김영훈,정춘해,박치영 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Evans syndrome is defined as a simultaneous or sequential occurrence of autoimmune hemolytic anemia and autoimmune thrombocytopenia. Autoimmune hemolytic anemia (AIHA) is usually induced by IgG warm autoantibody or cold-active IgM antibodies reacting specifically with antigens associated with a patient's RBC. AIHA is a fairly uncommon disorder, with estimates of the incidence at 1 to 3 cases per 100,000 per year. Mixed-type AIHA is a relatively uncommon form of AIHA, with studies noting the incidence of 7-8% among cases of AIHA. We experienced a patient, 46-year-old woman who was diagnosed having a very rare clinical presentation of mixed warm and cold antibody mediated Evans syndrome. She was treated with corticosteroid therapy only and has been maintaining a complete response for 15 weeks. 저자들은 혼합형의 자가면역성 용혈성 빈혈과 자가면역성 혈소판 감소증이 동시에 발생한 혼합형 Evans 증후군으로 진단하고 스테로이드 요법 후 혈액학적으로 회복된 상태로 15주가 지난 현재 steroid 5 mg/일 까지 감량한 상태에서 추적 관찰 치료중인 46세 여자 환자를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

동일한 시료에 대한 국내 기관간의 STR 분석결과 비교 : STR 유전자좌 분석법의 표준화 설정을 위하여

박종태,신경진,양윤석,우광만,이숭덕,이승환,이정빈,정연보,조승희,한길로,한면수,홍승범 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

This paper described a collaborative exercise intended to see what kinds of short tandem repeat (STR) loci are used in different DNA typing laboratories in Korea and to compare their results for the demonstration whether uniformity of DNA profiling results from different laboratory could be achieved in Korea Laboratories were asked to test five tissue DNAs using methods routinely used in each laboratory and to report the results to the coordinating laboratory. The exercise demonstrated that each laboratory was using different STR loci for the typing with different STR numbers,2 VNTRS,36 STRs and amelogenin in total, and the direct comparison of the results from all the laboratory for the 18 loci could not be done as only one laboratory submitted typing results. Among 21 loci for which several laboratories submitted typing results, results for 14 loci were the same and results for the other 7 loci were different depending on the participating laboratory. D1S80, F13A01, D16S539, D21S11, D18S51, D3S1744 were the loci with different typing results. Even in the cases where commercial kits were used, the results were not the same depending on the machines used, that is the capillary electrophoresis or the gel based electrophoresis. The reason for the different results, points about the standardization of the methods arid the profiling data were described.

오존공정을 이용한 염색폐수의 처리특성에 관한 연구

강용태,원태준,한상윤,고영발,박경덕 東亞大學校 建設技術硏究所 2008 硏究論文集 Vol.32 No.1

The wastewater from textile industry typically containing high alkalify, salts, organic matter, and high color. Textile wastewater is usually treated by anaerobic-aerobic activated-sludge process. The activated-sludge process is effective the reduction of organic matter, but generally does not remove color. Ozone process is one of the most effective process in removal of color for the textile wastewater. Ozone has a strong oxidized dissolution of organism, deceleration, deodorization, fumigation, etc., regarding to water. This study focused on the color removal of textile wastewater. In this study, textile wastewater was treated strongly with ozone at 650mg/hr and the flow rate through ozone contact tank was adjusted to 5L/min. In an application Ozone treatment, Color was generally decreased with time, however, COD removal effect was not that good. In this study, the removal efficiencies of CODcr and Color were 23.5%, 80.4% respectively.

관상동맥 혈류의 예비력 측정에서 ATP(Adenosine Triphosphate)와 아데노이신의 비교

김원,탁승제,김한수,신준한,조윤경,최옥경,임경수,최병일 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.6

Hypoallergenic and Physicochemical Properties of the A2 β-Casein Fraction of Goat Milk

Tae-Hwan Jung,Hyo-Jeong Hwang,Sung-Seob Yun,Won-Jae Lee,Jin-Wook Kim,Ji-Yun Ahn,Woo-Min Jeon,Kyoung-Sik Han2.6* 한국축산식품학회 2017 한국축산식품학회지 Vol.37 No.6

Goat milk has a protein composition similar to that of breast milk and contains abundant nutrients, but its use in functional foods is rather limited in comparison to milk from other sources. The aim of this study was to prepare a goat A2 β-casein fraction with improved digestibility and hypoallergenic properties. We investigated the optimal conditions for the separation of A2 β-casein fraction from goat milk by pH adjustment to pH 4.4 and treating the casein suspension with calcium chloride (0.05 M for 1 h at 25°C). Selective reduction of β- lactoglobulin and αs-casein was confirmed using sodium dodecyl sulphate-polyacrylamide gel electrophoresis and reverse-phase high-performance liquid chromatography. The hypoallergenic property of A2 β-casein fraction was examined by measuring the release of histamine and tumor necrosis factor alpha from HMC-1 human mast cells exposed to different proteins, including A2 β-casein fraction. There was no significant difference in levels of both indicators between A2 β-casein treatment and the control (no protein treatment). The A2 β-casein fraction is abundant in essential amino acids, especially, branched-chain amino acids (leucine, valine, and isoleucine). The physicochemical properties of A2 β-casein fraction, including protein solubility and viscosity, are similar to those of bovine whole casein which is widely used as a protein source in various foods. Therefore, the goat A2 β-casein fraction may be useful as a food material with good digestibility and hypoallergenic properties for infants, the elderly, and people with metabolic disorders.

열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

Generalized <i>M</i>-Ary Related-Prime Sequences with Low Correlation

HAN, Yun Kyoung,YANG, Kyeongcheol The Institute of Electronics, Information and Comm 2008 IEICE transactions on fundamentals of electronics, Vol.91 No.12

<P>In this paper we introduce new <I>M</I>-ary sequences of length <I>pq</I>, called <I>generalized M-ary related-prime sequences</I>, where <I>p</I> and <I>q</I> are distinct odd primes, and <I>M</I> is a common divisor of <I>p</I> - 1 and <I>q</I> - 1. We show that their out-of-phase autocorrelation values are upper bounded by the maximum between <I>q</I> - <I>p</I> + 1 and 5. We also construct a family of generalized <I>M</I>-ary related-prime sequences and show that the maximum correlation of the proposed sequence family is upper bounded by <I>p</I> + <I>q</I> - 1.</P>

New <tex> $M$</tex> -Ary Sequence Families With Low Correlation and Large Size

Yun Kyoung Han,Kyeongcheol Yang IEEE 2009 IEEE transactions on information theory Vol.55 No.4

<P>In this paper, we construct four M-ary sequence families from a power residue sequence of odd prime period <I>p</I> and its constant multiple sequences using the shift-and-add method, when M is a divisor of <I>p</I>-1. We show that the maximum correlation values of the proposed sequence families are upper-bounded by <I>2radicp</I> +5 or <I>3radicp</I> +4. In addition, we prove that the linear complexity of each sequence in the proposed families is either <I>p</I>-1 or <I>p</I>-[(<I>p</I>-1)/(<I>M</I>)]-1 . We also construct an M-ary sequence family from Sidel'nikov sequences of period <I>p</I> <SUP>m</SUP>-1 by applying the same method, when <I>M</I> is a divisor of <I>p</I> <SUP>m</SUP>-1. The proposed sequence family <I>F</I> <I>tilde</I> <SUB>s</SUB> has larger size than the known M-ary Sidel'nikov sequence families, whereas they all have the same upper bound on the maximum correlation.</P>