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      • 합, 차 빔 내에서 가섭 신호 동시 제거를 위한 적응 위상 모노펄스

        주경환,성하종,윤대희 대한전자공학회 1996 전자공학회논문지-B Vol.b33 No.3

        Monopulse technique has been widely used for a bearing estimation of a desired signal. This method can estimate the bearing of the signal with only one pulse, so computational load and complexity are low and its processes are simple. But if the desired signal incidents with interferences or multiple signals exist in the beams, the method fails to estimate correct signal angle. To solve this problem, the method to use adaptive array was proposed. In conventional adaptive array methods, sum beam was formed with fixed weights and ifference beam was formed with adaptive weights determined to minimize beamformer output power with one or more linear constraints, or an algorithm to minimize each sum beam and difference beams simultaneously using adaptively formed one basic beam. Theroretical analyses and simulation results show that the performance of the proposed method is superior to that of conventional algorithms.

      • 가을철에도 기생충 검사와 투약이 필요하다

        주경환,Ju, Gyeong-Hwan 한국건강관리협회 1987 건강소식 Vol.11 No.11

        지금까지 범국가적으로 실시되어 오던 학생검변제도가 연 1회로 축소되어 가고 있는 때 일수록 학생이나 자녀를 둔 가정에서는 각별히 가을 기생충검사와 구충에 관심을 가져야겠다.

      • KCI등재

        중국 연변지역 주요 기생충질환에 대한 혈청역학적 조사

        주경환,전복실,권혜수,조성원,이순옥,Joo, Kyoung-Hwan,Quan, Fu Shi,Kwon, Hye-Soo,Cho, Sung-Weon,Li, Shun Yu 한국농촌의학지역보건학회 1998 농촌의학·지역보건 Vol.23 No.2

        간흡충(Clonorchis sinensis), 폐흡충(Paragonimus westermani), 스팔가눔(sparganum), 뇌낭미충(Cysticercus cellulosae), 아니사키스(Anisakis spp.), 선모충(Trichinella spiralis), 개화충(Toxocara canis)에 대한 IgG항체반응을 ELISA를 이용하여 연변지역주민의 혈청역학적 조사를 시행하고 그 결과를 PC-SAS 시스템으로 통계분석하여 다음과 같은 결과를 얻었다. 1995년 10월부터 1997년 6월 사이에 수집된 총 975명의 혈청에 대한 검사결과 23.87%에서 한 종류이상의 혈청항체 양상을 나타내였다. 이중 간흡충증은 5.74%, 폐흡충증은 4.92%, 낭미충증은 1.54%, 스팔가눔증은 8.51%, 아니사키스증은 1.85%, 개회충증은 12.51%, 선모충증은 7.08%의 혈청항체 양성률을 나타내었다. 판정된 양성혈청을 통계분석한 결과 간흡충(p<0.01), 혜흡충(p<0.01), 아니사키스(p<0.05), 개회충(p<0.01), 선모충(p<0.01)의 각 연령그룹비교에서 통계학적으로 유의한 차이를 나타내었고 스팔가눔증은 성별 사이에 유의한 차이가 보였다(p<0.05). 간흡충과 폐흡충은 50대 연령층에서 높은 양성항체가를 나타내는 반면 개회충과 선모충은 20대에서 높은 항체가를 보여주었다. 또한 내과질병으로 않고 있는 환자혈청은 낭미충증을 제외한 6종류 윤충류에서 정상대조인과 비교하여 볼 때 모두 통계학적으로 유의한 차이를 나타내었다(p<0.05 혹은 p<0.01). 즉 환자가 정상대조인보다 혈청양성률이 훨씬 높았다. 이상의 결과는 물론 선충사이의 교차반응이 있을거라고 추측되며 정확한 진단을 위해서는 EITB를 시행해야 한다고 생각한다. 이번 조사는 중국 연변에서 처음으로 되는 혈청역학조사이며 앞으로 기생충진환 퇴치대책에 아주 중요한 기초자료가 될 수 있을 것으로 생각한다. Antibody responses(IgG) to Paragonimus westermani. Clonorchis sinensis, Cysticercus cellulosae, Sparganum Anisakis simplex, Toxocara canis and Trichinella spiralis were studied. The ELISA technique was performed to determine the prevalence of above helminthic diseases. 975 cases obtained from Yanbian of China during October, 1995 to July, 1997 were examined with a positive antibody titer of 5.74% in clonorchiasis, 4.92% in paragonimiasis, 1.54% in cysticercosis. 8.51% in sparganosis, 1.85% in anisakiosis, 12.51% in toxocariasis, and 7.08% in trichinosis respectively. And 23.87% in showed positive antibody titer at least one of the seven helminths. The differences of the age and sex in the positive sera were analysed by the Chi-squared test and the level of significance accepted was p<0.05. The significant differences in positive antibody production were P.W.(p<0.01). C.S.(p<0.01), A.S.(p<0.05). T.C.(p<0.001), and T.S.(p<0.01) respectively in age groups. sparganosis(p<0.05) in sex groups. Other parasites showed that there were no significant differences among age groups and sex groups(males and females). Higher positive antibody rate of C.S. and P.W. occured in the 50-59 years old and those of T.C. and T.S. happened in the 20-29 years old. Patients of internal disease showed more positive antibody titer, that is to say, there was significant difference between positive rate of internal diseases and that of control (p<0.01. p<0.05) in 6 helminths except cysticercosis. The result showed that some cross reactions existed among nematodes, and the developed techniques(EITB) should be done for a correct diagnosis. Also the prevalence of some important helminths may be evaluated from the result and it would be a basic data for controlling parasitic diseases in Yanbian.

      • 肝吸蟲感染에 따른 血淸 IgE와 血液內好酸球의 變動樣相에 관한 硏究

        朱炅煥,林漢鍾 고려대학교 의과대학 1982 고려대 의대 잡지 Vol.19 No.1

        The present study aimed to clarify the influence of single or repeated infection of Clonorchis sinensis on the IgE level and eosinophil counts of rabbit, and to determine the relationship between degree of infection and eosinophil counts or IgE level in the patients infected with C. sinensis. Various numbers of metacercariae isolated from flesh of the second intermediate host, Pseudorasbora parva, were directly introduced to the rabbits. Single infection group was divided into heavy, moderate and light infection groups, in which 2,000, 500 and 50 metacercariae of C. sinensis were administered respectively. Repeated infection group was also divided into heavy, moderate and light infection groups, in these cases 200, 100 and 10 metacercariae were fed biweekly for five times respectively. Infection was confirmed by detection of the eggs of C. sinensis in feces five weeks after primary infection. Whole blood and sera were collected prior to infection, and on 1,3,5,7, and 9 weeks after infection from the inner marginal vein of rabbit's ear respectively. As a control, whole blood and sera were also sampled from the non-infected rabbits. Total eosinophil counts, differential count, and IgE levels were examined. On the other hand, a total of 50 patients infected with C. sinensis was examined their degree of infection (EPG), total eosinophil counts and differential counts of white blood cells of 50 c. sinensis infected patients were exanined. Forty-six sera were sampled from patients infected with C. sinensis and the serum IgE levels were evaluated. In analysis of serum IgE level, Phadebas IgE PRIST® radioimmunoassay technique was applied. The results are as follows: 1. Total eosinophil counts of repeated infection group of rabbits were significantly higher than that of single infection group. Total eosinophil counts of non-infected rabbits showed ranges of 0~65/㎣ blood during 9 weeks of examination. In the infected rabbits of heavy infection group, total eosinophil counts increased rapidly and reaching to peak on the 5th week after infection. These values maintained until the end of examination in 9th week (140/㎣ in single and 250/㎣ in repeated group). However, total eosinophil counts of light and modertate infection did not show rapid increase. On the contrary they increased slightly and continuously until 9 weeks after infection. Similar results were obtained from the differential counts of eosinophil. 2. In the examination of the patients infected with C. sinensis correlation between EPG and eosinophil count was recongnized. Coefficient of correlation was, r=0.61, rank correlation r=0.700, and regression equation was Yc(total eosinophil counts)=0.04χ (EPG)+372. 3. Total serum IgE levels in the patients infected with C. sinensis showed remarkably elevated value. mean values were 1,167 IU/㎖±1,172, but correlation with degree of infection was not significant statistically. Influences of repeated infection of C. sinensis on the IgE level were not able to investigate, because IgE was not detected in Phadebas IgE PRIST® using rabbit as an experimental animal.

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