혈관질환 정보관리 시스템

김동익,김덕경,허세호,이병붕,김용신,김은숙,문지영,도영수,신성욱,김동수,김만태,진재욱,김용신 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.1

As medical technology progresses rapidly, there is a rise in the average age along with the Korean dietary lifestyle becoming more westernized, which leads to an increase in the number of vascular disease patients in Korea. Thus, we need to manage the medical information of a disease systematically in order to diagnose and treat constructively. However, since there has been no standardized method of man agement to date, a great deal of information could not be properly utilized nor studied. Therefore, the departments of Cardiology, Radiology and Neurology of Samsung Seoul Hospital recently got together to develop an information management system called the Vascular Data System. This program was developed to be run on win98 O/S, upper Pentium Ⅲ, and upper 128 MB Memory, and its source code is Dephi 4.0. It was configured for the user to set the configurations as well as do a variety of search and analysis. If this program were to be updated continuously, it may be used extensively as well as in various parts of clinical research activities.

韓國河川의 流出率과 流出指標로서의 洪水直前 流量

金熙鍾,柳又秀,金佳鉉,申東守,韓健模,全裕燦 東亞大學校 大學院 1984 大學院論文集 Vol.9 No.-

This paper is a study on relation between run-off ratio and antecedent discharge, run-off ratio and antecedent discharge per unit area, antecedent discharge and antecedent precipitation, by the data from the five major river basins in Korea and the small river basins in Pusan. The Nak-Dong rivers(An-Dong upper stream) f=0.4780+0.0124 ln qA r=0.99 qA=0.3368e0.1101R r=0.99 f=0.5793+0.0146 ln(qA/A) r=0.99 The Nak-Dong rivers except Ga-song station f=0.2017-0.0840 ln qA r=0.75 f=0.7012+0.0750 ln(aA/A) r=0.71 The Han rivers f=-0.0035+01267 on qA r=0.75 f=1.1311+0.1263 ln(qA/A) r=0.71 L=302.9064-43.8490 ln qA r=0.84 The Geun rivers(Mu-sin Cheon) f=0.295+0.1823 ln qA r=0.93 f=0.8417+0.1823 ln(qA/A) r=0.93 L=40.0456+62.0346 ln qA r=0.94 The Yeong-san rivers f=0.3766+0.0598 ln qA r=0.79 f=0.8084+0.0599 ln(qA/A) r=0.79 The Seom-jin rivers f=-1.3875+0.6505 ln qA r=0.92 f=2.1633+0.3465 ln(qA/A) r=0.76 Small river basin in Pusan f=0.3635+0.1120 ln qA r=0.87

우리나라에서 솔껍질깍지벌레의 분포확산

임유진,이상명,김동수,김준범,최광식,이신혜,박정규,이동운,Lim, Eu-Gene,Lee, Sang-Myeong,Kim, Dong-Soo,Kim, Joon-Bum,Lee, Shin-Hye,Choi, Kwang-Sik,Park, Chung-Gyoo,Lee, Dong-Woon 한국응용곤충학회 2012 한국응용곤충학회지 Vol.51 No.1

솔껍질깍지벌레는 우리나라 곰솔림의 주요한 해충의 하나이다. 본 연구는 우리나라에서 솔껍질깍지벌레의 분포를 알아보기 위하여 7개도 3개 광역시, 91개 시군구, 686 읍면동의 해송림에서 2010년 밀도를 조사하였다. 5개도 2개 광역시에서 솔껍질깍지벌레가 서식하고 있었는데 시군구별로는 조사대상의 64.8%인 59개 시군구에서 서식이 확인되었다. 솔껍질깍지벌레의 분포는 남해안 전역과 동해안의 포항, 서해안의 충남 보령지역까지 분포하였다. 충북과 대전광역시 및 제주도에서는 솔껍질깍지벌레의 분포가 확인되지 않았다. 부산지역은 16곳의 모든 구에서 솔껍질깍지벌레가 분포하였고, 시군 단위에서는 전남 해남군의 솔껍질깍지벌레 평균밀도가 1.713마리/0.785 $cm^2$로 가장 높았으며 읍면동 단위에서는 해남군 송지면이 6.36마리/0.785 $cm^2$로 가장 높았다. 곰솔 가지 내의 솔껍질깍지벌레 밀도와 솔껍질깍지벌레가 서식하고 있는 빈도와는 높은 상관관계가 있었다(상관계수=0.89). The black pine bast scale, $Masucoccus$ $thunbergianae$ (Hemiptera: Margarodidae), is a serious pest of the Japanese black pine, $Pinus$ $thunbergii$, in Korea. The distribution of the black pine bast scale was examined, looking overall at 686 towns (eup), townships (myeon) or neighborhoods (dong). There were Japanese black pine ($Pinus$ $thunbergii$) forests in 91 cities, counties (gun) and borough (gu), in seven provinces and three metropolitan cities during 2010. Black pine bast scale were found in 64.8% of cities or counties or borough (59) in 7 provinces and 3 metropolitan cities, and were distributed in all South Costal regions, Pohang in East Costal region and Boryeong in West Costal region. Chungcheongbukdo, Daejeon and Jeju did not have black pine bast scale. All the gu regions in Busan had black pine bast scale, of which the area with the highest prevalence was Haenam in Jeollanamdo (1.713 crawlers/0.785 $cm^2$). Songji-myeon had the highest occurrence rate (6.36 crawlers/0.785 $cm^2$) from the towns, township and dong. The density of black pine bast scale in twigs was highly correlated with percentage of the sample with scale (Correlation coefficacy=0.89).

B형 간염 동반 원발성 간암 환자에서의 CYP2D6와 NAT2 다형현상에 관한 연구

신동일,이광수,최연남,황기은,조율희 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.2

The CYP2D6 and N-acetyltransferase (NAT2) are polymorphic enzymes which are expressed in the hepatocyte in a genotype-determined manner. CYP2D6 and NAT2 are known to be involved in the inactivation and activation of various mutagens and carcinogens, respectively. The activities of the two enzyme systems are associated with the genetic susceptibility of many human cancers. This study was performed to determine the genotype frequencies of the two enzyme systems in primary hepatocellular carcinoma patients and healthy controls. One hundred healthy controls and 55 liver cancer patients were analyzed by polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP). The results are as followings:1. In the healthy controls, CYP2D6 wild type allele frequency was 0.985 and CYP2D6^*4 frequency was 0.015, and no CYP2D6 poor-metabolizer was detected. No significant differences were found in hepatocellular carcinoma patient group. 2. Frequencies of F, S1, S2 and S3 alleles of NAT2 system were 0.725, 0.01, 0.14 and 0.125 in controls, respectively. The genotype frequencies were found to be 0.91 of rapid acetylator and 0.09 of slow acetylator. No significant differences were found in hepatocellular carcinoma patient group. 3. These results suggest that the distribution of CYP2D6 and NAT2 polymorphisms is very unique in Korean populations characterized by extremely low frequency of CYP2D6 poor-metabolizer and NAT2 slow acetylator. CYP2D6 and NAT2 polymorphisms seemed not to play an important role in the hepatic carcinogenesis in Korean population.

Taxol 합성에 관한 연구 Ⅰ : O-(tert-Butyldiphenylsily1)-cis-5-methyl-4-hepten-6-yn-1-ol의 합성 Synthesis of O-(tert-Butyldiphenylsily1)-cis-5-methyl-4-hepten-6-yn-1-ol

신동수,박두천,주우홍,김형국 國立 昌原大學校 基礎科學硏究所 1994 基礎科學硏究所論文集 Vol.6 No.-

O-(tert-Butyldiphenylsily1)-cis-5-methyl-4-hepten-6-yn-1-ol, an intermediate in the synthesis of taxol, was efficiently synthesized from 3-methyl-2-penten-4-yn-1-ol by sequential alcohol/bromide interchange [NBS, PPh_(3), CH_(2)Cl_(2), -30℃, 82%], displacement with the lithium salt of tert-butylacetate [LDA, THF, -78 to 23℃, 84%], LAH reduction, and silylation [tBuPhSiCl, imidazole, CH_(2)Cl_(2), 45℃, 88%].

多國籍企業과 國際寡占形成

申東洙 홍익대학교 경영연구소 1983 경영연구 Vol.6 No.-

신입 부사관 후보 대학생과 일반대학생의 혈압, 신체조성 및 체력 비교 연구

하수민,신상근,김동두 釜山大學校 附設 體育科學硏究所 2014 體育科學硏究所 論文集 Vol.31 No.-

The purpose of this study was to comparison a study on blood pressure, body composition and physical fitness in department of noncommissioned officer D college Students and P college students. For this study, participants were into four groups, D college male students(A, n=102), P college male students(B, n=51), D college female students(C, n=42), P college female students(D, n=44). The test data were analyzes by independent t-test, and the alpha level of p<.05 was set for all tests of significance. The results of the research were as follows. Group A was %Fat(p<.05) significantly higher than Group B and Group A was grip strength, sit-ups(p<.001) significantly lower than Group B. Group C was weight, BMI(p<.05), %Fat(p<.001) significantly higher than Group D and Group C was grip strength(p<.05), sit-ups(p<.01) significantly lower than Group D. Therefore, D College NCOs students need correct lifestyle and regular exercise. 본 연구는 부산지역 소재 D대학 신입 부사관 후보 대학생과 P대학 일반대학생의 혈압, 신체조성 및 체력을 비교 연구 하였다. 연구결과에서 다음과 같은 결론을 얻었다. 부사관 후보 남자대학생의 체지방률은 일반 남자대학생 보다 유의하게 높았으며, 부사관 후보 여자대학생의 체중, BMI, 체지방률은 일반 여자대학생 보다 유의하게 높았다. 체력은 부사관 후보 남․여 대학생 모두 악력, 윗몸일으키기가 일반 남․여 대학생들 보다 유의하게 낮게 나타났다. 이상의 연구 결과 D대학 신입 부사관 후보 대학생은 바람직한 군인화를 위한 올바른 생활습관과 규칙적인 운동 실천이 요구된다.

批判的 思考의 本質과 批判的 思考敎育에 관한 探究

신동로,오현수 全北大學校 敎育大學院 1998 敎育論叢 Vol.18 No.-

The purpose of this study is to examine the history of the terms 'a critical thinking' and to survey the nature and the education of one. The critical thinking movement seems to have begun with the work of John Dewey from 1910 to 1939 and his use of the terms 'reflective thinking' and 'inquiry' which he based on the scientific method. From 1940 to 1961, the meaning of the term 'critical thinking' broadened to include the examination of statements. From 1962 to 1979, The meaning of the term 'critical thinking' narrowed to exclude problem solving and the scientific method and include only the assessment of statements. With the contributions of Robert H. Ennis, John E. Mcpeck. Harvey Siegel, and Richard W. Paul from 1980 to the present, the meaning of the term 'critical thinking' has broaden to include aspects of problem solving. The meaning of the terms 'critical thinking' and 'problem solving' overlapped and intersected each other. The core meaning of the critical thinking is the propensity and the skills for participate in the thinking activities with the reflective skepticism about the objects of thinking within one's cognizance. The aims for the teaching of critical thinking and reasoning is to be well used the logical skills to judge about the decision-making and problem solving situation. Formal and informal logical education is essencial to success for the education of critical thinking. The education of critical thinking have to be learned through the debate and the discussion.

인축적 미생물의 인방출과 세포내 저장물질 합성관계

신응배,김미경,홍준혁,공동수 한국물환경학회 2004 한국물환경학회지 Vol.20 No.6

Biological phosphorus removal is characterized by complex interactions between different intracellular components of energy as PHA. Therefore, fundamental understanding of the behavior of the intracellular components and their influence on the removal of phosphorus is essential before control strategies to stabilize the proper process. The purpose of this study is to investigate relationship between release of phosphorus and synthesis of intracellular storage polymer. Mass of stored intracellular storage polymer was 21.2 ㎎ PHA/L, 28.8 ㎎ PHA / g MLSS. And phosphorus release/ intracellular storage polymer synthesis rate was 1.8545 ㎎ stored polymer/㎎ Phosphate. In the aerobic phase, mass of PAOs synthesis is 49.37 ㎎ PAOs/L. And PAOs fraction was 6.7-6.9%. Thus intracellular storage polymer synthesis by PAOs is calculated as 493㎎ PHA / g PAOs.

Methyl Orange에 依한 Disopyramide Phosphate의 分光光度 定量法

申台容,嚴東玉,黃甲洙 又石大學校 1990 論文集 Vol.12 No.-

A singly charged methyl orange anion(M. O) was found to be extracted with Disopyramide phosphate(DP) as a 1:1 complex in dechloroethane. MO-dichloroethane system gave a yellow color for DP, while in the absence of DP, an organic phase showed almost no color. In this way, the spectrophotometric method was in vestigated for the determination of DP by soivent extraction. The results obtained were as follow: 1. The maximum absorption wavelength of the reaction product was 420nm(ε=6.45×10^3.ℓ·moℓ^-1.㎝^-1) 2. Dichloroethane was the best extracting solvent among the several organic solvents and the most suitable pH range was 5.8~6.3 3. Linear relationship was found between absorbance and concentration in the range of 1 x 10^-5M∼10^-4M for DP. 4. This method was suitable for the spectrophotometric determination of DP in mixed pharmaceutical preparation.