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      • 일지역 여대생의 가족계획 및 인공임신중절에 대한 태도 및 지식에 관한 연구

        황미혜 中央醫學社 1990 中央醫學 Vol.55 No.12

        The attitude and knowledge toward family planning and induced abortion of 387 students of 2 colleges in Andong area were investigated from Oct. 29 to Nov. 5, 1990 with following results. The correct concept of family planning as controlling the number and the interval between children was recognized by 84.2 % of subjects. 91.5 % of subjects approved family planning. The most ideal age of their marriage was 29.98. The most desired age difference between a couple was 3-4 yrs. (51.2 %), the bride being younger than the bridegroom. 82.1 % of subjects wanted to have more than two children after marriage. 61.0 % of subjects expressed that life without children would be incomplete. Rhythm method and basal body temperature were the most desired contraceptive method (37.7 %), followed by oral pill (14.5 %) and condom (12.7 %). As for attitude of induced abortions 43.2 % of subjects answered that abortion can be permitted if there is a proper reason, on the other hand 29.7 % of subjects answered that abortion must be prohibited in any case. 93.5 % of subjects expressed that induced abortion would be harmful to the mother's health. The number of those who agreed that the pregnancy of the poor and single and the unwanted pregnancy might be aborted is 50.4 %, 33.9 % and 40.5 % respectively.

      • 울산시 보건소 당뇨교실에 참가한 당뇨환자의 식습관 실태에 관한 연구

        홍순명,황혜진,최순호,정은미 울산대학교 2000 생활과학논문집 Vol.2 No.1

        본 연구의 목적은 당뇨환자의 특성, 식사조절, 운동여부와 그 외의 식습관을 조사함으로써, 이를 영양교육과 영양상담을 하는 데에 있어 기초자료로 이용하고자 한다. 울산시 동구 보건소를 내원한 당뇨환자 112명을 대상으로 조사한 결과를 요약하면 다음과 같다. 대상자의 당뇨보유기간은 7.58 ± 7.30년이었고, 공복시 혈당과 식후 2시간 후 혈당은 각각 180.92 ± 71.42mg/dl 247.64 ± 105.26mg/dl으며, 합병증 증세로는 저혈당 증세가 가장 많았으며, 심혈관질환, 망막장애, 백내장, 당뇨족, 신장장애, 말초신경장애 등 여러 합병증도 존재함을 알 수 있었다. 당뇨병으로 인한 증상으로는 눈흐림 50.5%, 피로 46.7%로 대부분의 조사대상자가 느끼는 증상이었고, 그 외 잦은 소변, 갈증, 짜증, 기타 증상(손발 절임, 어지러움, 몸이 무겁다, 변비, 가래)이 나타났다. 조사대상자들의 38%는 식사조절을 하였으나 대부분이 식품 교환표를 이용하지 않는 것으로 나타났고, 음주와 흡연을 한다는 경우는 각각 15.7%로 나타났다. 보건소를 이용하는 환자들은 대부분 고령인 점을 고려하여 이들이 쉽게 이해할 수 있으며 식생활에 적응할 수 있는 영양교육프로그램의 개발이 필요하다고 본다. The purpose of this study is to investigate the diabetes subject of health center for nutrition education. 112 subjects were evaluated with Questionnaire., Diabetic duration were 7.58 years and the fasting and 2-hour postprandial glucose level were 180.92 ±71.42mg/dl, 247.64 ± 105.26mg/dl. The complications were hypoglycemia > weakness in legs > renal, failure > peripheral neural disorder, and diabetic symptoms were sight disturbance > fatigue> polyuria. 62% of subjects were not executed diet therapy and 15.7% of subject had drinking and smoking habit. The most influential referents were medical professionals including doctors, nurses, dieticians, so their role in diet therapy should be emphasized. Since diabetic patients commuting to a local health center were mainly illiterate and received little formal education, it is very important to develop and assess appropriate nutrition education for them.

      • 울산시 보건소 당뇨교실에 참가한 당뇨환자의 교육 효과에 관한 연구

        홍순명,황혜진,최순호,정은미 울산대학교 2000 생활과학논문집 Vol.2 No.1

        최근 유병률이 증가하고 있는 당뇨병 환자에 대한 영양교육의 효과를 알아보기 위하여 울산시 보건소에서 환자 36명을 대상으로 교육을 실시하였다. 설문지를 통하여 교육 전과후의 신체계측, 혈당, 당뇨병의 합병증과 임상 증상을 조사하였고, 식습관의 변화와 교육의 효과 등을 분석한 결과를 요약하면 다음과 같다. 당뇨교육 후 체중이 감소한 경향으로 나타났고, BMI(kg/m')는 교육 전후가 거의 변화가 없는 것으로 나타났다. 당뇨교실 전후의 혈당치를 조사한 결과 공복시 혈당이 교육전보다 교육 후 줄어들었다(p<0.1). 식후 혈당치는 170.0 ± 70.71mg/dl에서 158.50 ± 40.31mg/dl로 줄어드는 경향으로 나타났다. 교육전후의 건강증상의 상관관계를 보면 눈흐림 증상이 유의적으로 감소된 것으로 나타났고, 갈증을 느끼는 경우도 감소한 경향이 나타났다. 교육 후에 교육 전보다 식사 조절을 많이 하는 것으로 나타났고, 식품교환표를 이용하여 식사조절을 하는 것으로 나타났다. 당뇨교실교육은 91.7%가 도움이 되었다고 당뇨교실이 효과적인 것으로 나타났다. The purpose of this study was to evaluate the effect of nutrition education for diabetic patients commuting to a local health center in Ulsan city. We examined the effect of nutrition education on physical characteristics and blood glucose by comparing before and after education with questionnaire. All diabetic subjects were interviewed for general characteristics, diabetic complications, food habits and education effect. BMI was no difference before and after education. Fasting glucose level were significantly lower after education and postprandial glucose level were decreased after education (158.50 ± 40.31mg/dl) compared before education(170.0 ± 70.71mg/dl). but there was no significance in postprandial glucose. When we compared before and after diabetic symptoms, sights disturbance were decreased aftar education and the symptoms of polydipsia were decreased after education. The diabetic subjects were executed diet therapy after education. This study showed that nutrition education for diabetic patient was effective in significant changes.

      • KCI등재

        축구선수의 Detraining과 Retraining이 혈청지질 및 호르몬농도에 미치는 영향

        정정화,박재현,채종훈,성혜련,황지인,윤미숙,노금선,윤종관,윤영학,노순덕,정경숙,박일규,김은희,박현태,박상갑 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1

        The purpose of this study was to investigate the effects of detraining and retraining on serum lipid and hormones in soccer players. Subjects were seven male high-school soccer players. V˙O_2max was determined for each subjects by administering a treadmill test(initial speed: 90m/min, grade: 5%, increasing speed per 3 min: 30m/min). Serum lipid(T-C, TG, HDL-C LDL-C) and hormones(epinephrine, norepinephrine, growth hormones, cortisol) were assayed pre and post detraining in 10, 20, 30 days after retraining. The repeated ANOVA was used to determine significant differences. The 0.05 level of significance was as critical level for the study. The results of the study were as follows: 1. V˙O_2max(ml/min) were 3576.3±204.2ml/min pre detraining, 3234.1±198.9 ml/min post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/min) were 3601.4±170.9 ml/min. There were significantly(p<.05) increased in retraining periods. 2. V˙O_2max(ml/kg/min) were significantly(p<.05) decreased from 62.3±2.9 ml/kg/min to 55.9±4.7 ml/kg/min in detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/kg/min) were 62.4±3.4ml/kg/min, 62.7±2.3ml.kg/min, 67.3±7.2ml/kg/min respectively. There were significantly(p<.05) increased in retraining periods. 3. T-C were significantly (p<.05) increased from 166.6±8.5mg/dl to 175.3±10.3 mg/dl in detraining. In 10, 20, 30 days after retraining, T-C were 160.1± 3.2mg/dl, 156.7±3.7mg/dl, 140.3±9.0mg/dl. There were significantly(p<.05) decreased in retraining periods. 4. HDL-C were 61.4±6.6mg/di pre detraining, 5.3±6.6mg/dl post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, HDL-C were 56.9±7.1mg/dl, 56.4±9.2mg/dl, 57.7±9.1mg/dl respectively. There were no significant difference in retraining periods. 5. The hormones(epinephrine. norepinephrine, growth hormone, cortisol) were changed as same patterns. Epinephrine were 26.0±7.0[g/ml pre detraining, 24.6±3.2pg/ml post detraining. In 10, 20, 30 days after retraining, epinephrine were 26.9±5.6pg/ml, 30.6±6.2pg/ml, 29.4±5.6pg/ml respectively. There were no significant difference in retraining periods. In conclusion, HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were decreased, T-C, LDL-C and TG were increased in detraining. But HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were increased, T-C, LDL-C and TG were decreased in retraining.

      • KCI등재후보

        연쇄상구균의 약제내성과 전이성 R-plasmid의 특성

        김종훈,임대환,이창훈,이수정,이월라,황미혜,김은희 한국어병학회 2003 한국어병학회지 Vol.16 No.1

        본 연구는 넙치 병어에서 분리된 연쇄상구균들의 항균제 내성 경향을 파악하고, 약제내성의 전이에 관여하는 R plasmid를 검출하여, 분리 균들 내에서 이들 plasmid의 분포를 알아보기 위하여 실시하였다. 넙치 병어에서 분리된 연쇄상구균 40 균주의 대부분은 ampicillin, doxycycilne (DOXY), erythromycin, florfenicol, flumequine, norfloxacin, osolinic acid, oxytetracycline (OTC)의 2~5약제에 동시내성을 나타내었다. 이들 내성균으로부터 내성 전이에 관여하는 R plasmid (pST9)가 검출되었으며, OTC와 DOXY내성이 R plasmid에 의하여 수용균인 Streptococcus sp.로 전이가 이루어졌다. 전이성 R plasmid의 분포를 알아보기 위하여 colony 혼성화 반응을 실시한 결과, 40 분리 균주 중 6 균주에 동일한 DNA 구조의 R plasmid가 존재하는 것으로 나타났다. 그러므로 이들과 DNA 구조가 다른 R plasmid도 넙치병어에서 분리되는 연쇄상구균의 약제내성에 관여하고 있음을 시사하였다. MICs of 8 chemotherapeutic agents against forty streptococcal isolates were determined. These strains were isolated from diseased olive flounder, Paralichthys olivaceus, and showed 2~5 multiple drug resistance against different antibacterial agents including ampicillin, doxycycline (DOXY), erythromycin, florfenicol, flumequine, norfloxacin, oxolinic acid, and oxytetracycilne (OTC). In conjugation experiment, we found transferable R plasmids carrying OTC and DOXY resistance determinant in 3 drug resistance strains analyzed. Six out of 40 isolates showed positive signal in colony hybridization with the R plasmid DNA (pST9) as a probe. It suggests that other types R plasmid different from pST9 is also involving in multiple drug resistance of streptococci isolated from olive flounder.

      • SCOPUSKCI등재
      • 일부 흡연 대학생의 지각된 스트레스와 흡연실태에 대한 상관관계 연구

        강초록,권시내,권혜림,박수경,송인혜,오해인,이미지,한승아,황선아,김수지 이화여자대학교 간호과학대학 2003 이화간호학회지 Vol.- No.37

        In spite of the seriousness of smoking harm has been developed these days. the increase of national smoking rate and that the people in the twenties are especially leading the rise of national smoking rate is an important issue of national health. Smoking of the university students can occur health problem and cause loss of manpower and expenses in their social activity period. So then the actual state for prevention of smoking and development of a program to prohibit smoking has to be seized urgently and starting with the study of the realities of university students, the effort to find a related fluent of smoking has to be studied. Related to this, the purpose of this study is to seize the general characteristics of smoking university students and to find out the relationship between perceived stress and smoking status among smoking university students. In addition, by collating the relationship between perceived stress and smoking status among smoking university students we have the purpose to furnish the basal data of stress care, the best way to cope with stress through group training and the plan for nursing implementation to decrease the smoking rate. For this study, a survey was conducted for 204 smoking university students of 13 universities in Seoul from 9th of May to 16th of May, 2003. The collected data was analyzed by t-test, Pearson Correlation and ANOVA in the statistical packages SPSS/PC. Major findings of this study are as follows; 1. Of the 204 respondents 85.4% of them were male and 14.6% of them were female. The average age of the sample was 23.19 years old and 41.8% of them were in senior, 21.4% in junior, 16.9% in sophomore, 19.9% in freshman grade. The major motivation to start smoking was 'because of curiosity'(33.8%) and the first smoking experience was at 'senior high school' (41.9%) and at 'college' (41.9%). 2 The highest scored stress factor of smoking university students were stresses about school work. 3. 72.7% had experience to quit smoking at least one or more times. Most of the reason to keep on smoking was 'short will to quit'(51.0%) and the smoking place was usually at 'school' (41.4%). Most respondents for the number ofsmoking friends were '5 people and above' (73.2%). 4. There was a negative relationship between the general characteristics and the entire perceived stress, however, there was a positive relationship between the general characteristics and the perceived stress in 4 categories which is 'sex distinction', 'major of study', 'residence form' and' inmate'. 5. There was a negative relationship between the general characteristics and the entire smoking status, however, there was a positive relationship between the general characteristics and the smoking status in 2 categories which is 'presence of hobby' and 'number of smoking friends'. 6. There was a negative relationship between the perceived stress and the smoking status. Through this study we have seized the relationship between the general characteristics, perceived stress and the smoking status of smoking university students. There was a positive relationship between some of the general characteristics with the perceived stress and the smoking status of smoking university students. Also there was a negative relationship between the perceived stress and the smoking status.

      • SCISCIESCOPUS

        Decursin inhibits UVB-induced MMP expression in human dermal fibroblasts via regulation of nuclear factor-κB.

        Hwang, Bo-Mi,Noh, Eun-Mi,Kim, Jong-Suk,Kim, Jeong-Mi,Hwang, Jin-Ki,Kim, Hye-Kyung,Kang, Jae-Seon,Kim, Do-Sung,Chae, Han-Jung,You, Yong-Ouk,Kwon, Kang-Beom,Lee, Young-Rae D.A. Spandidos 2013 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.31 No.2

        <P>Decursin, a coumarin compound, was originally isolated from the roots of Angelica gigas almost four decades ago, and it was found to exhibit cytotoxicity against various types of human cancer cells and anti-amnesic activity in vivo through the inhibition of AChE activity. However, the anti-skin photoaging effects of decursin have not been reported to date. In the present study, we investigated the inhibitory effects of decursin on the expression of matrix metalloproteinase (MMP)-1 and MMP-3 in human dermal fibroblast (HDF) cells. Western blot analysis and real-time PCR revealed that decursin inhibited the ultraviolet (UV)B-induced expression of MMP-1 and MMP-3 in a dose-dependent manner. Decursin significantly blocked the UVB-induced activation of nuclear factor-κB (NF-κB). However, decursin showed no effect on MAPK or AP-1 activity. In this study, decursin prevented the UVB-induced expression of MMPs via the inhibition of NF-κB activation. In conclusion, decursin may be a potential agent for the prevention and treatment of skin photoaging.</P>

      • Associations of the Polymorphisms in <i>DHRS4</i>, <i>SERPING1</i>, and <i>APOR</i> Genes with Postmortem pH in Berkshire Pigs

        Hwang, Jung Hye,An, Sang Mi,Kwon, Seul Gi,Park, Da Hye,Kim, Tae Wan,Kang, Deok Gyung,Yu, Go Eun,Kim, Il-Suk,Park, Hwa Chun,Ha, Jeongim,Kim, Chul Wook Informa UK (TaylorFrancis) 2017 Animal biotechnology Vol.28 No.4

        <P>Postmortem pH is a main factor influencing the meat quality in pigs. This study investigated the association of postmortem pH with single-nucleotide polymorphisms (SNPs) in the fourth member of the short-chain dehydrogenase/reductase family (DHRS4), the first member of serpin peptidase inhibitor, clade G (complement inhibitor) (SERPING1), and the apolipoprotein R precursor (APOR) genes in Berkshire pigs. The study included 437 pigs, and genotyping was conducted using the GoldenGate Assay (Illumina, San Diego, CA, USA). DHRS4, SERPING1, and APOR polymorphisms were significantly associated with pH(45) or pH(24) (p<0.05). SERPING1 was also statistically significantly associated with water holding capacity (p<0.05), which is closely associated with postmortem pH. These results suggest that SNPs in the DHRS4, SERPING1, and APOR genes have potential for use as genetic markers for the meat quality in pigs.</P>

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