혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

완전 방실차단을 동반한 급성 심근염

이유선,정진옥,박용규,박형서,노상필,정승현,김정희,이재환,최시완,성인환 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

급성 심근염환자에서 발행한 완전 방실차단을 영구 심장박동 조율기로 치료한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Myocarditis, an inflammatory process involving the myocardal wall, may be caused by most infectious agents. Irrespective of its etiology, it presents commonly with evidence of heart failure, hypotension, and various electrocardiographic abnormalities. Patient with myocarditis may be asymptomatic or may have a rapidly progressive fatal disease. Medical management of patients with myocarditis includes specific therapy for underlying infection and control of the complication of myocarditis such as congestive heart failure and arrhythmia. Recently we had experienced myocarditis with complete atrioventricular block in 37-year-old man. Although he had shown complete recovery of heart failure, he had shown complete atrioventricular block, so we inserted permanent pacemaker. We report it with review of the literature.

국가대표 남자 체조선수들의 실수 원인에 대한 질적 연구

정진근,김정완 한국스포츠심리학회 2003 한국스포츠심리학회지 Vol.14 No.1

본 연구의 목적은 국가대표 남자 체조선수들이 인식하고 있는 실수 원인을 면담을 통해 심층적으로 분석하여 실수 원인에 대한 정보를 제공함으로써 우수한 경기력 발휘에 어려움을 겪고 있는 일반선수들이나 현장에서 선수를 지도하는 지도자들에게 실수에 대한 대처방안을 강구할 수 있도록 하기 위함이다. 본 연구에서는 제14회 아시안 게임에 참가한 국가대표 남자 체조선수들을 대상으로 실수 원인을 밝혀내기 위하여 심층면담을 하였으며 면담을 통해 얻어진 자료를 귀납적 방법으로 내용 분석을 하였다. 내용 분석 한 결과는 다음과 같다. 실수의 원인은 신체적 요인, 심리적 요인, 인적 요인, 환경적 요인으로 모두 4가지 범주로 분류되었다. 신체적 요인의 범주 안에는 1가지의 원자료가 분류되었으며, 심리적 요인의 범주 안에는 가장 많은 8가지의 원자료가 분류되었다. 그리고 인적 요인에 3가지의 원자료가 분류되었고 환경적 요인에 1가지의 원자료가 분류되었다. 이러한 결과를 바탕으로 경기중 실수를 줄이기 위해서는 심리적 실수 유발 요인을 통제하는 것이 중요하며 따라서 실수의 심리적 원인에 적절히 대처할 수 있는 훈련과 연습이 필요하다는 제안을 하였다. The purposes of this study are to analyze the reasons of mistakes that male gymnastic players recognize through the interviewing and to plan to deal with those problems by presentation the informations about the reasons of mistakes to the general gymnastic players and the directors. This study makes the targets for the analysis the male gymnastic players that participated in the 14th Asian Games as the members of the national team. The materials that was drawn through the depth interviewing are analyzed inductively. The results of this study are as follows : The reasons of mistakes are classified into four categories : the physical factor, the psychological factor, the human relations factor, and the environment factor. There is a raw date in the physical factor, and 8raw date in the psychological factor. Then, there are 3raw date in the human relations factor, and a raw date in the environment factor. With these results in mind, the following recommendations may be possible. First, it is important that the psychological reasons are controlled to reduce the mistakes in the match. Second, it is necessary that the gymnastic players must practice and be trained to prepare the psychological reasons of the mistakes.

북한이탈주민의 외상 후 스트레스 장애와 자연살해세포 활성

김병창,정성훈,임효덕,최종혁,전정희,전양환 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.5

Objectives : The objective of this study was to evaluate an association between posttraumatic stress disorder (PTSD) and altered immunity m North Korean defectors who were more likely to develop medical conditions and other stress-related psychiatric disorders. Methods : Twenty-four North Korean defectors with PTSD and twenty-two controls without PTSD were recruited from the resettlement and training center for North Korean defectors in South Korea. Peripheral T lymphocyte subsets, natural killer(NK) cells, NK cell activity and plasma hormones (ACTH and cortisol) were obtained from all subjects. We also applied the Hamilton Rating Scale for Depression (HAM-D) and Hamilton Rating Scale for Anxiety (HAM-A) for all subjects. Results : We found NK cell activity was relatively lower than number of NK cells in North Korean defectors with PTSD. Subjects with PTSD had higher HAM-D and HAM-A scores than controls. However, there were no statistical differences in ACTH. cortisol, CD3, CD4, CD8, CD4/CD8 ratio, CD19 and CD56 between the two groups. Conclusion : These findings suggest North Korean defectors with PTSD show higher levels of depression, anxiety and impaired or weak immune function in NK cells.

객체 모델의 재상요을 위한 라이브러리 구조

김진수,김정아,이경환 중앙대학교 기술과학연구소 1996 기술과학연구소 논문집 Vol.26 No.-

Analogical learning은 문제를 해결하고 학습하는 하나의 효과적인 방법이다. 한 영역에서 또다른 영역으로의 관련성은 추론과 학습의 기반이 된다. 모델러가 이미 구축되어 있는 모델들을 제공받을 수 있다면 생산성과 이해용이성이 증가될 수 있다. 모델러는 부분적인 모델로 모델링을 시작하여 라이브러리에 저장된 유사하게 일치되는 객체 모델을 모델링에서 사용할 수 있다. 그것 또한 라이브러리에 저장된 객체 모델의 재사용이 된다. Analogical agent는 객체 또는 프레임워크를 이용하여 라이브러리를 브라우징하고 몇가지 유사한 모델을 제공한다. Analogical learning의 결과로는 객체모델링과 어플리케이션 영역에 익숙하지 않은 사람도 모델을 쉽게 구축할 수 있고, 객체모델링에 대한 그들만의 패권도 가질 수 있다. Analogical learning is an effective way of human problem solving and learning methodologies. The relation from one domain to other domains is the base of reasoning and learning. If modeler could be supported with previous constructed model, the productivity and understandbility can be improved. Starting with partial model, modeler can preserve it with analogically matched object model stored in a library. It is also the reuse of object model stored in the library. analogical agent accept the partial object or framework and browse the library with analogical matching function and provide several analogous model. As a result of analogical learning, novice to object modeling and application area can construct the model easily and they easily and they can have their own pattern for object modeling.

국내선 항공여객교통 수요예측

김경환,이정호 慶尙大學校生産技術硏究所 1996 生産技術硏究所論文集 Vol.12 No.-

The purpose of this study is not only to establish models and methods for forecasting the demand of domestic air transportation passengers but also to provide useful data for forecasting the demand of air passengers through statistical test. The first step of this study was analyzing the demand of air passengers by using the gravity and the abstract models that generally used for city-pair travel demand studies. The second step was analyzing the demand of air passengers by using the multinomial logit model that calculates the split rate of each mode by using travel service variables. And the estimated air passengers by these models and the observed air passengers were compared. The third step was estimating the changed modal split that caused by introducing the High Speed Rail. In order to estimate the change, the Pivot-Point Method was applied. The results of this study are as follows: - The statistical significance of the gravity model is not high enough. - The statistical values of the abstract and the logit models are significant, but the logit model is more realistic than the abstract model, based on estimated values. - It is estimated that the air passengers of Seoul-Pusan and Seoul-Taegu routes may be decreased by 88% and 90% respectively by introducing the High Speed Rail.

Erythromycin 내성 포도알균의 유도형 Macrolide-Lincosamide-Streptogramin B (MLS_(B)) 내성 표현형 빈도

김경희,박순호,박필환,안정열,서일혜 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

Background: Inducible MLS_(B) (macrolide-lincosamide-streptogramin B) resistance in staphylococci is not detected by standard susceptibility test methods. Failure to identify inducible MLS_(B) resistance may lead to clinical failure during clindamycin therapy. We determined the prevalence of inducible MLS_(B) resistance in erythromycin-resistant staphylococcal isolates. Materials and Methods: We evaluated all 2,792 non-duplicate staphylococcal strains: 1,402 Staphylococcus aureus and 1,390 coagulase-negative staphylococci (CoNS) isolated from May 2008-June 2009 at one-unoversity hospital. Testing for inducible MLS_(B) was accomplished by the disk approximation test (D-test) in accordance with the recommendations of the Clinical and Laboratory Standards Institute (CLSI). Results: Of the 2,792 staphylococcal isolates, 892 S. aureus isolates and 740 CoNS isolates were resistant to erythromycin. Among the 892 erythromycin-resistant S. aureus isolates, the overall prevalence of inducible MLS_(B) was 21.3% (16.2% of MRSA and 76.3% of methicillin-susceptible S. aureus). Among the 740 erythromycinresistant CoNS isolates, the overall prevalence of inducible MLS_(B) was 16.5% (16.0% of methicillin-resistant CoNS and 18.7% of methicillin-susceptible CoNS). The D-test was positive in 88.8% of S. aureus and 28.4% of CoNS isolates, which were erythromycin-resistant and clindamycin-susceptible. Conclusions: There are some variations in the prevalence of inducible MLS_(B) resistance in clinical staphylococcal isolates. It is important that clinical laboratories report inducible MLS_(B) resistance for erythromycin-resistant and clindamycinsusceptible staphylococcal isolates.

관상동맥 질환에서 SDF-1α의 농도

김보영,박용규,박형서,노상필,정승현,이유선,이정우,이재환,최시완,정진옥,성인환 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

Atherosclerosis is now viewed as an inflammatory disease of the vascular system. Expression of several chemokines, including monocyte chemoattractant protein(MCP)-1, MCP-4, RANTES(regulated on activation normal T-cell expressed and secreted), and interleukin-8(IL-8) are increased in human atherosclerotic plaques compared with normal vessels. They are involved in the pathogenesis of atherosclerosis and plaque rupture by activating and directing leukocytes into the atherosclerotic lesions. However, some are involved in homeostatic functions such as normal leukocyte traffic and growth regulation. SDF-la is a multi-functional cytokine that is involved in myelogenesis, hematopoiesis, angiogenesis and injured gastric mucosal regeneration in the gastric ulcer patient. SDF-la is recently shown to be highly expressed in atherosclerotic plaques and a potent platelet agonist. At least in high concentrations, SDF-la may mediate antiinflammatory and matrix stabilizing effects in unstable angina. Many studies are going on to know the function of SDF-la in coronary artery diseases. I investigated the difference of the plasma level of SDF-la between control group and coronary artery disease group. Total 75 subjects were enrolled. The diagnosis of coronary artery disease was confirmed in all patients by coronary angiography. Control subjects in this study were confirmed normal by coronary angiography. Clinical profile and risk factors were also reviewed. Control subjects in this study were 27 (M=10, F=17). Plasma for the study was collected before the angiography and centrifuged. SDF-la analysis was performed by ELISA. Plasma level of SDF-la is significantly increased in patients with stable angina(n=20) and unstable angina group(n=28) compared with healthy control group(n=27). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases. In this study, plasma level of SDF-la is increased in patients with stable angina and unstable angina groups compared with healthy control group(P<0.05). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases.

청각장애자 운동지도를 위한 프로그램 고찰

김정수,박정래,노일환,원충희,김흥식,강신일,박찬홍,김달영,이철원,이찬규 公州大學校스포츠科學硏究所 1987 스포츠科學硏究所論文集 Vol.- No.1

Hearing impairement in varying degrees constitutes one of the most common disabilites affecting school aged children. Eight out of every 1,000 students under the age of twenty have significant hearing loss. Hearing disabilities range from slight to total loss of sound perception. Statistics indicate that only one out of every ten hearing impaired children will become deaf. Most motor activities can be included students may possess low levels of static and/ or dynamic balance, but the greatest majority possess normal motor and physical capabilities. All the hearing impaired youngsters should be properly assessed and given the identical testing batteries as normal children. Hearing impaired students have, essentialy, a communication handicap and suffer from inability to understand verbal instructions. All physical educators should be able to use minimal finger spelling and signing for hearing impaired students.

도시지역에서의 적정택시대수 산정

김경환,순정운 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

From ride share aspect, Korean taxis are functioning as public transit. However, taxi-operators are generating social problems on issuing taxi licenses every year, because there is no reasonable method for estimating adequate number of taxis in a city. Thus, a method for estimating adequate number of taxis was developed in this study, the method consists of three criteria; one is the criterion based on optimal taxis' occupancy rate considering optimal waiting time of passengers, the optimal income of operators, and working hours of taxi divers, another is criterion on taxi-passenger chane, the other is the criterion on traffic conditions. Also, a new observation method of taxis' occupancy rate was suggested. In this study, Chinhae was selected as the study city. Followings are the results of this study. First, by using the new observation method of taxis' occupancy rate based on taxi traffic count reliable occupancy data could be collected with low expenses. Second, the results applying the model suggested in this study to Chinhae showed that preset number of axis is adequate and the results matched well with the real situation of Chinhae.