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      • KCI등재

        Laparoscopic Transabdominal Transfer of Blastocysts in Korean Black Goats

        조상철,조종기,신상태 사단법인 한국동물생명공학회 2017 한국동물생명공학회지 Vol.32 No.2

        As a part of the effort to improve post-transfer survival rate of embryos in Korean black goats, a technique for laparoscopic uterine transfer of blastocysts was carried out. A total of 26 transferrable embryos (morula to expanded blastocysts) were transferred to 13 recipient goats via transabdominal laparoscopic method. In consequence of our hormone protocol, 65% of the recipients (13/20) were found to have synchronized estrus. After confirmation of corpus luteum in each recipient goat, a Babcock laparoscopic forceps was inserted into the lower abdominal cavity to hold a uterine horn and fasten it near the peritoneum without causing injury. Then 7.5cm long 16G IV catheter was inserted directly into the uterine lumen through the abdominal wall. After removal of the stylet of the IV catheter, the embryo transfer tube (identical in size to the stylet and loaded with blastocysts) was inserted into the uterine lumen through the catheter to unload the embryos. Of the 13 estrus synchronized recipients, 9 were transferred blastocysts and 4 were transferred molurae (2 embryos in each recipient) in uterine ipsilateral to the ovary with corpus luteum. Four of the 9 recipients which blastocysts were transferred using this method has been confirmed pregnant (44.4% pregnancy rate).

      • KCI등재

        양성 충수돌기궤양에서 발생한 급성 하부위장관출혈 1예

        조상철,서영호,박정수,박상현,정안덕,이봉규,주소영,이남훈,송근영,송성환,이인경,고향미 대한소화기내시경학회 2008 Clinical Endoscopy Vol.36 No.3

        급성 하부위장관출혈의 원인은 치질이 가장 흔하며, 그 외에 게실증, 혈관형성이상, 허혈결장염 등이 있으나, 충수돌기가 원인이 되는 경우는 드물다. 저자들은 신선혈변을 주소로 내원한 33세 여자 환자의 대장내시경에서 충수돌기의 출혈을 확인한 후 수술을 통해 얻은 조직검사에서 충수돌기의 양성궤양이 진단된 1예를 경험하였기에 문헌고찰과 함께 보고한다.

      • KCI등재
      • KCI등재

        Fabry Disease Presenting with Hypertrophic Cardiomyopathy and Tricuspid Regurgitation

        조상철,유한욱,이재원,장정윤,허란,송종민 한국심초음파학회 2016 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.24 No.4

        A 71-year-old female who was diagnosed with nonobstructive hypertrophic cardiomyopathy since 1999 presented with dyspneaand severe edema on both legs. For the management of her symptom, cardiac surgery including tricuspid annuloplasty, Maze operationand right atrial reduction plasty was performed. During follow-up after cardiac surgery, a plasma α-galactosidase activitywas checked for the screening of Fabry disease and the result was around lower normal limit. DNA analysis was implemented forconfirmation and it revealed a heterozygote α-galactosidase mutation at exon 6 [c.901C>T (p.Arg301Ter)]. This case suggeststhat Fabry disease might be easily undetected, and clinical suspicion is critical.

      • KCI등재

        관광호텔 식당선택에 미치는 상황적 영향 연구

        조상철 관광경영학회 2000 관광경영연구 Vol.8 No.-

        The purpose of this study is to examine the features of situational influence in the hotel restaurant Choice and to help the managers of Hotel restaurant in marketing, management and sales promotion in such a competitive situation of the hotel industry. More specifically, it has investigated the differences between the restaurant choice and choice factors in situational influence and identified there are also differences between hotel choices and choice factors in situational influence and demographic variables. This study should be considered more since the sample was not completely random and need to deveiop the dimension on situational influence factors. Therefore, the more systematic and continuous study should be executed to overcome those kind of limits.

      • KCI등재후보

        Metabolic Syndrome Causes Cardiovascular Disease under Stable Statin Medication

        조상철,Hoonhee Lee,Hyo-Jung Nam,한기훈 한국지질동맥경화학회 2017 지질·동맥경화학회지 Vol.7 No.2

        Objective: Statins are known to prevent only 30-50% of cardiovascular disease(CVD) by reducing low-density lipoproteincholesterol (LDL-C). There is a controversy about whether metabolic syndrome(MS) can increase the risk of CVD. The aimof this study is to investigate whether MS can increase the risk of CVD, even after LDL-C is ideally controlled by taking statins. Methods: As a retrospective observational study, we investigated CVD events of 909 patients (61.3±10.2 years old) byreviewing medical records for at least 1 year before and after taking statins respectively, from June 2005 to February 2008,and analyzed the risk factors of CVD. Results: During the study period (881.4±232.8 days), 46 cases of CVD events occurred in patients with a very high riskof CVD and in patients with a high risk of CVD. In patients with a very high risk of CVD, 56.8% (21 cases over 37)of CVD events occurred in patients who achieved LDL-C goal (<70 mg/dL). A total of 9 events developed among highrisk patients who reached LDL-C goal (<100 mg/dL). The patients with MS revealed significantly higher rates of CVDevents [p=0.015; hazard ratio (HR) 3.033; 95% confidence interval (CI) 1.184-7.768]. Significantly higher rates of CVDevents were also found in subgroup analysis of the patient with a past history of CVD events [p=0.017; HR 3.431; 95%CI 1.183-9.956]. Similar pattern was demonstrated in patients with diabetes [p=0.049; HR 2.738; 95% CI 0.963-7.782]. Cox regression analysis identified metabolic syndrome [p=0.025; HR 5.237; 95% CI 1.235-22.204], a past history of CVDevents [p=0.000; HR 5.349; 95% CI 2.321-12.327], basal LDL-C level [p=0.024; HR 1.013; 95% CI 1.002-1.025] andtotal cholesterol level after statin therapy [p=0.024; HR 0.978; 95% CI 0.959-0.997] as independent predictors of CVDamong LDL-C goal achieved patients. Conclusion: Metabolic syndrome is the independent risk factor of CVD events in high risk patients with or without apast history of CVD events or diabetes. In these patients, statins could not prevent CVD events effectively. (J Lipid Atheroscler2017 December;6(2):75-83).

      • 정량적 연관규칙 탐색 기법을 이용한 시계열 분석

        池元哲,趙相喆 弘益大學校 科學技術硏究所 2001 科學技術硏究論文集 Vol.12 No.-

        Association Rule Mining,(Agrawal et al., 1993) is an exploration method which searches associative relations between item sets in large database. Association Rule Mining, in general, searches association between qualitative items. To adapt Association Rule Mining to quantitative attributes, Quantitative Association Rule Mining is introduced in 1996. Sequential Pattern Mining and N-Dimensional Inter Transaction Mining are applications of Association Rule for Time series analysis by extending time dimensions to the Association Rule. Analyzing complex time series, such as stock price movement, using quantitative model is limited, and Technical Analysis like a chart analysis is an alternative approach for them. Technical Analysis recognizes patterns, and analyzes impacts effected by the pattern. In this work, we defined pattern on the time series syntactically and analyzed the patterns and recognized the patterns which is frequently emerges in the time series, and, explored the other patterns as an impact of discovered patterns in former step. For this purpose, we used N-dimensional Inter Transaction Association Rule and syntactically described pattern(of both quantitative, qualitative attribute). So it enables pattern recognition, analyzing impacts and forecasting of complex time series such as stock prive movement

      • KCI등재

        40세 이하의 한국인에서 발생한 급성 심근경색증의 임상적 특성

        조상철 ( Sang Cheol Cho ),정명호 ( Myung Ho Jeong ),김원 ( Weon Kim ),최옥자 ( Ok Ja Choi ),정안덕 ( An Doc Chung ),강원유 ( Won Yu Kang ),조용찬 ( Yong Chan Cho ),안영근 ( Young Keun Ahn ),김완 ( Wan Kim ) 대한내과학회 2008 대한내과학회지 Vol.74 No.5

        목적: 우리나라에서 연령에 따른 급성심근경색증 환자의 동맥경화 위험인자와 기본적 특성, 관상동맥 조영술 소견 및 주요 심장사건 등에 대해 직접적으로 비교한 결과는 많지 않다. 방법: 1997년 6월부터 2006년 2월까지 급성심근경색증으로 관상동맥 조영술을 실시한 환자 중 연령이 40세 미만인 환자 108명을 I 군으로 하였고, 이와 비교된 70세 이상 환자 64명을 II 군으로 하였다. 기본 임상적 특성, 심장초음파, 관상동맥 조영술 및 주요 심장사건 발생 등에 관하여 비교분석 하였다. 주요심장사건은 사망, 표적혈관의 재협착, 급성심근경색증의 재발과 관상동맥 우회술 시행 등으로 정의하였다. 결과: 1) 두 군 모두에서 남성의 빈도가(I군 vs. II군: 94.6% vs. 56.1%) 많았으며, 특히 I 군에서 더 많았다(p<0.001). 2) 동맥경화의 위험인자는 I 군에서 흡연(78.7 vs. 46.9%, p<0.001)과 고지혈증(45.4 vs. 14.1%, p<0.001)이 많았고, II군에서 고혈압(23.1 vs. 40.6%, p=0.01)과 당뇨병(11.6 vs. 34.4%, p<0.001)이 많았다. 3) 심초음파의 좌심실 구혈율은 I군에서 높았다(55.1±14.1% vs. 50.5±14.1%, p=0.042). 4) 혈중 고감도 C반응단백(1.7±2.6 vs. 3.4±4.4 mg/L, p=0.015)과 homocysteine (11.5±7.0 vs. 15.3±9.7 μmol/L, p=0.029) 은 II 군에서 더 높았다. 5) 관상동맥 조영술에서 표적혈관의 경우 II군에서 우관상동맥이 높은 빈도를 보였으며(35.2% vs. 50.0%, p=0.021), 병변 형태의 분류에서 유의한 차이는 없었다. 병변혈관 수에서 단일혈관 질환이 I 군에서 많았으며 (78.7% vs. 59.4%, p=0.007), 시술 전 Thrombolysis in Myocardial Infarction (TIMI) 혈류등급은 I 군에서 grade II-III (58.3% vs. 42.2%, p=0.040)의 빈도가 높아 더 좋은 혈류등급을 보였다. 6) 86.6%의 환자에서 평균 2.5년의 임상추적이 이루어졌으며, 심장사망은 II 군에서 높았으나(2.1% vs. 15.1%, p=0.002), 전체 주요 심장사건 발생률은 양군 사이에 차이는 없었다. 결론: 한국에서 40세 이하에 발생한 급성심근경색증 환자는 남성, 흡연 및 고지혈증 등의 위험인자를 가지고 있었으며, 관상동맥 조영술에서 단일혈관 질환이 많았고, 추적관찰 결과 고령의 환자에 비해 심인성 사망은 적었다. Background/Aims: It is known that mortality increases with age for patients who suffer with acute myocardial infarction (AMI). Yet there isn`t much data on the clinical characteristics and long-term prognosis of young patients with AMI. Methods: We analyzed two groups of patients with AMI who underwent coronary angiogram: 108 patients younger than 40 years as group I and 64 patients over 70 years old as group II. We compared the baseline clinical characteristics, the echocardiographic and coronary angiographic findings, and the major adverse cardiac event (MACE). Results: Male gender (94.4% vs. 56.1%, respectively, p<0.001), smoking (78.7% vs. 46.9%, respectively, p<0.001) and hyperlipidemia (45.4% vs. 14.1%, respectively, p<0.001) were more frequent in group I, whereas hypertension (23.1% vs. 40.6%, respectively, p=0.015) and diabetes (11.6% vs. 34.4%, respectively, p<0.001) were more common in group II. The left ventricular ejection fraction (55.1±12.2% vs. 50.5±14.1%, respectively, p=0.042) was higher in group I. The serum levels of high sensitivity C-reactive protein (1.7±2.6 vs. 3.4±4.4 mg/L, respectively, p=0.015) and homocysteine (11.5±7.0 vs. 15.3±9.7 μg/L, respectively, p=0.029) were higher in group II. One vessel disease (78.7% vs. 59.4%, respectively, p=0.007) and good Thrombolysis In Myocardial Infarction (TIMI) flow (TIMI II-III, 58.3% vs. 41.2%, respectively, p=0.040) were more common in group 1. There were no differences between the two groups for the development of MACE during the 28±21 months of clinical follow-up, but cardiac death was lower in group I than in group II (2.1% vs. 15.4%, respectively, p=0.002). Conclusions: Male gender, smoking and hyperlipidemia were the major risk factors of Korean young AMI patients. In addition, single vessel disease and good TIMI flow were more frequent and cardiac death was less frequent in the younger AMI patients.(Korean J Med 74:515-522, 2008)

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