증례 : 우연히 발견된 간의 혈관근지방종 1예

이태희 ( Tae Hee Lee ),임의혁 ( Eui Hyeog Im ),허규찬 ( Kyu Chan Huh ),최용우 ( Young Woo Choi ),정동진 ( Dong Jin Chung ),김범경 ( Bum Kyeong Kim ),강영우 ( Young Woo Kang ) 대한내과학회 2005 대한내과학회지 Vol.69 No.-

저자들은 23세 남자에서 우연히 발견된 간내 종물로 세침 흡인 생검상 간의 혈관근지방종으로 진단된 1예를 문헌고찰과 함께 보고하는 바이다. Angiomyolipoma is a common benign tumor in the kidney, composed of blood vessel, smooth muscle cells, fat and myelocomponent, but hepatic angiomyolipoma is a rare benign mesenchymal neoplasm. Radiologic findings are not specific because the composed elements are variable in proportion and distribution. Recently, we experienced a case of angiomyolipoma in a incidental tumor of the liver in a 23-year-old man with history of tuberculous pericarditis. The tumor, measuring 1.7×1.8 cm, was located in the segment Ⅴ of the liver. Diagnosis was aquired by fine needle aspiration biopsy under ultrasonographic guidance. Microscopically, it showed smooth muscle cells, lipocytes and blood vessels. Immunohistochemically, the tumor cells were positive for HMB-45, S-100 protein, focally positive for SMA, but negative for cytokeratin, anti-hepatocyte antigen and chromogranin. (Korean J Med 69:S787-S792, 2005)

소하천 자동수문의 최적설계를 위한 강도 해석

이태희 ( Tae Heui Lee ),정규원 ( Kyu Won Jeong ),주진원 ( Jin Won Joo ) 충북대학교 산업과학기술연구소 2011 산업과학기술연구 논문집 Vol.25 No.1

As the energy resources are becoming exhausted, much efforts are given to develop new energy resources. Among the many kinds of energy water resource is very important for both people and agriculture. Therefore both of the government and the prefecture conduct many projects for rivers and even small watercourses. In this paper water gate which could be installed in the small watercourse was designed and the strength was analysed. Because the gate had complicated structure in order to reduce material cost, finite element method was used to find the optimal dimension.

UV / TiO2 / H2O2 시스템을 이용한 페놀의 분해

김태민,이진규,김성준,이태희 ( Tae Min Kim,Jin Kyu Lee,Sung Joon Kim,Tae Hee Lee ) 한국화학공학회 1996 화학공학의이론과응용 Vol.2 No.1

Ceramic Membrane 을 이용한 광촉매 분리장치 개발

이진규,김태민,서정원,김성준,이태희 ( Jin Kyu Lee,Tae Min Kim,Jung Won Seo,Sung Joon Kim,Tae Hee Lee ) 한국화학공학회 1996 화학공학의이론과응용 Vol.2 No.2

크기가 큰 측방발육형종양의 치료 전략: 분할점막절제술 혹은 점막하박리술

강상구 ( Sang Goo Kang ),이석호 ( Suck Ho Lee ),정승규 ( Seung Kyu Chung ),신재민 ( Jae Min Shin ),전성란 ( Seong Ran Jeon ),이태희 ( Tae Hee Lee ),김현건 ( Hyun Gun Kim ),김진오 ( Jin Oh Kim ) 대한장연구학회 2011 Intestinal Research Vol.9 No.3

Background/Aims: The therapeutic strategy between endoscopic piecemeal mucosal resection (EPMR) and endoscopic submucosal dissection (ESD) for large laterally spreading tumors (LSTs) has not been clearly defined. The aim of this study was to compare the clinical outcomes between EPMR and ESD in patients with large LST. Methods: From July 2006 to September 2010, 106 patients who underwent endoscopic resection for large (>20 mm) LSTs were included in our retrospective analysis. Results: Baseline characteristics of the patients and tumors were not different between two groups except for location (EPMR-right colon, ESD-rectum). The en bloc resection rate and complete resection rate were significantly higher in the ESD group than those in the EPMR group (EPMR vs. ESD, 53.5% vs. 88.6, P<0.01, 45.1% vs. 71.4%, P=0.01, respectively). However, total procedure time was significantly shorter in the EPMR group (21.3 min vs. 44.4 min, P<0.01). Furthermore, the rates of complication including perforation and bleeding were significantly lower in the EPMR group than those in the ESD group (perforation, 1.4% vs. 11.4%, P=0.02; bleeding, 4.2% vs. 17.1%, P=0.03, respectively). During 19.9 months of follow-up, no significant difference was observed in terms of recurrence (1.5% vs. 3.2%). Non-granular, pseudo-depressed type (LST-PD) showed a significantly higher presence of adenocarcinoma and deeper submucosal invasion than other types of LSTs. Conclusions: The therapeutic strategy for choosing between EPMR and ESD for large LST lesions should be determined based on the macroscopic findings of their subtype. En bloc resection with ESD should be applied to LST-PDs due to their higher rate of submucosal invasion. (Intest Res 2011;9:211-216)

전이성 췌장암 환자의 장기 생존 1예

표진실,최용우,구훈섭,송경호,김용석,김선문,이태희,허규찬,강영우,Jin Sil Pyo,Yong Woo Choi,Hoon Sup Koo,Kyung Ho Song,Yong Seok Kim,Sun Moon Kim,Tae Hee Lee,Kyu Chan Huh,Young Woo Kang 대한소화기암연구학회 2014 Journal of digestive cancer reports Vol.2 No.2

Pancreatic cancer is well known to have a poor prognosis and poor responses to both of chemotherapy and radiation therapy. We report a metastatic pancreatic cancer treated successfully with chemotherapy and radiation therapy. A 71-year-old female with epigastric pain and weight loss was diagnosed as advanced pancreatic cancer with main vessels invasion and multiple mesenteric lymph node's metastasis. She was taken chemotherapy of gemcitabine single regimen and radiation therapy. Although she experienced one recurrence and concomitant primary lung cancer, she has survived for over 7 years with no symptoms. The authors report this case of long term survival in metastatic pancreatic cancer after chemoradiation therapy.

만성 신부전과 동반된 일차성 알도스테론증

김용수 ( Yong Soo Kim ),최훈영 ( Hoon Young Choi ),김현진 ( Hyun Jin Kim ),김동기 ( Dong Ki Kim ),정인현 ( In Hyun Jung ),김형종 ( Heung Jong Kim ),이태희 ( Tae Hee Lee ),윤수영 ( Soo Young Yoon ),최규현 ( Kyu Hyun Choi ),강신욱 ( 대한신장학회 2003 Kidney Research and Clinical Practice Vol.22 No.1

Background : Early detection and treatment of chronic kidney disease (CKD) are important for inhibition of kidney disease progression and prevention of cardiovascular complications. Treatment of Anemia that is frequently accompanied with CKD, are important for prevention of cardiovascular complications. The lastest K/SOQI-CKD guideline targets early detection and treatment of kidney disease, and the study for these are necessary in Korea. In Korea, until mowadays, the study for prevalence, severity of anemia and influencing factors on anemia in CKD, were rare. Thus in our center, we classified patient for severity of CKD as K/DOQI-CKD guideline and studied prevalence, severity of anemia and influencing factors on anemia. Methods : According to K/DOQI-CKD guideline, patients were staged by GFR calculated by Adbbreviated MDRD Study Equation. Anemia was defined by Hb lessl than 10.0 g/dL below which hemodynamic change develops. We examined the frequency of anemia and independent factors that influences on anemia in study patients. Results : Mean creatinine levels for stage 1 to 5 were 0.87±0.15 (0.7-1.1) mg/dL; 1.04±0.18 (0.8-1.4) mg/dL; 1.69±0.36 (1.1-2.7) mg/dL; 2.90±0.66 (1.9-4.7) mg/dL; 5.01±1.28 (3.3-8.8) mg/dL. Mean Hb levels and percentage of anemic patients in each stages were 12.95±1.46 (10.5-15.4) g/dL, 0%; 13.31±2.20 (7.8-17.7) g/dL, 10.3%; 11.32±2.07 (7.4-16.6) g/dL, 25.5%; 10.10±1.71 (6.7-14.0) g/dL, 54.8%; 9.21±1.53 (6.2-12.2) g/dL, 76.9%. The frequency of anemia were high in Diabeltes Mellitus Mellitus (DM) compared to Non-Diabeltes (Non-DM) at stage 3, 4, 5 [36.7 vs 12.0% (p=0.06); 70.6 vs 35.7% (p=0.000); 100 vs 64.7% (p=0.06)]. Multivariate logistic regression analysis revealed that DM as etiology (OR 2.53, p=0.033 compared with Non-DM), Albumin level (OR of 5.38 p=0.001 for 3.0-1.4 compared with 4.0-5.3 g/dL) were independent factor determing anemia state in addition to K/DOQI guideline stage. GFR, sex, DM, Albumin level were independent factors associated with hemoglobin levels (R^2=0.571, p<0.001). Conclusion : Anemia in CKD was developed relatively early and frequently at stage 3 (Cr, 1.69±0.36 mg/dL, 25.5%) and more aggravated as decreasing renal function (stage 4, 5; 54.8%, 76.9%). DM as underlying disease, hypoalbuminemia were, independently influenced Anemia development.

말기 신부전으로 진행된 다낭성 신증 환자에서 신대체 요법간의 비교

최훈영 ( Hoon Young Choi ),구영석 ( Young Suk Goo ),김동기 ( Dong Ki Kim ),김현진 ( Hyun Jin Kim ),김형종 ( Heung Jong Kim ),이태희 ( Tae Hee Lee ),정인현 ( In Hyun Jung ),강신욱 ( Shin Wook Kang ),최규헌 ( Kyu Hun Choi ),이호영 ( 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.6

목 적 : 다낭성 신증을 진단받은 환자 중 말기 신부전으로 진행된 환자를 대상으로 각 신대체 용법 환자 군간의 임상적 특징, 기술 생존율, 생존율 등을 조사하여 비교 분석하고자 하였다. 방 법 : 1980년 1월부터 2001년 12월까지 연세대학교 의관대학 세브란스병원 신장내과에 내원하여 다낭성 신증을 진단받고 말기 신부전으로 진행되어 신대체 요법을 시행받은 환자들은 대상으로 후향적 연구를 시행하였다. 결 과 : 총 70예의 환자 중 남자가 41예 여자가 29예이었으며, 다낭신 진단당시의 평균 연령은 45.6±10.7세이었고, 다낭신 진단으로부터 말기 신부전으로 이행될 때까지 평균 기간은 5.1±5.6년이었다. 신 이식을 한 환자군은 19예, 복막투석 치료를 받은 환자군은 26예, 그리고 혈액투석 치료를 받은 환자군은 25예이었다. 다낭신 진단 당시와 말기 신부전 진단 당시의 평균 연령은 이식 환자군이 유의하게 낮았다(p<0.05). 다낭신 진단으로부터 말기 신부전으로 이행될 때 까지의 평균 기간은 세 군간에 의의있는 차이가 없었다. 말기 신부전 진단 당시 혈액요소질소, 크레아티닌, 크레아티닌 청소율, 혈청 총 단백, 알부민, 칼슘, 인, 헤마토크릿 등은 세 군간에 유의한 차이를 보이지 않았으며, 혈색소는 혈액투석 환자군에서 의의있게 낮았다 (p<0.05). 말기 신부전 진단 당시 고혈압을 가진 환자는 전체 70명 환자 중 50명으로 가장 많았으며, 그 외 뇌혈관 질환, 심혈관계 질환, 간염, 당뇨 등을 동반한 환자들이 있었다. 각 신대체 요법의 기술 생존율은 복막투석 환자군에서 다소 떨어지는 양상이었으나 세 군간에 유의한 차이는 없었다. 복막투석 환자군에서 복막투석을 중단했던 경우는 총 10예로 복막염이 3예, 탈장이 2예, 초여과 장애가 1예, 복막 투석액 유출이 1예로, 7예 모두 혈액투석으로 전환하였으며 이외 사망으로 중단된 경우가 2예, 이식으로 전환한 경우가 1예이었다. 각 신대체 요법에서의 생존율은 복막투석 환자군과 이식환자군에 비해 혈액투석 환자군에서 생존율이 낮게 나타났으나 유의하지 않았다. 사망은 총 7예가 있었으며 혈액투석 환자에서 3예, 복막투석 환자에서 2예, 그리고 이식환자에서 2예가 있었고, 사망원인으로는 감염이 4예로 가장 많았으며, 출혈이 2예, 그리고 악성종양 1예가 있었다. 결 론 : 말기 신부전으로 진행된 다낭성 신증 환자에서 각 신대체 요법을 시작할 당시의 임상 양상은 유의한 차이를 보이지 않았으며, 기술 생존율이나 생존율에서도 의의있는 차이를 발견할 수 없었다. Background : Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorder that accounts for 8-10% of patients receiving renal replacement therapy in Unites States and Europe, and approximately 2% in Korea. ADPKD patients on renal replacement therapy constitute a particular group with typical clinical characteristics and differences from other patients on renal replacement therapy. The objective of this study was to assess clinical features, morbidity, mortality and technical survival in end stage renal disease (ESRD) patients with ADPKD and compare these between each renal replacement therapy. Methods : We retrospectively analyzed 70 ADPKD patients who received renal replacement therapy in Yonsei university medical center (Jan. 1980-Dec. 2001) Results : Among a total of 70 patients, 41 patients were male and 29 patients were female. Mean age was 45.6±10.7 years and average time from diagnosis of ADPKD to start of renal replacement therapy was 5.1±5.6 years. As the initial mode of renal replacement therapy, 25 patients started on hemodialysis 26 patients started on CAPD and 19 patients received renal transplantation. Clinical features and laboratory findings at the initiation of renal replacement therapy had no significant differences between each renal replacement therapy. Cumulative and technical survival in ESRD patients with ADPKD receiving each renal replacement therapy had no significant differences according to Kaplan-Meier. Seven patients died within study period, including 3 hemodialysis patients, 2 CAPD patients and 2 renal transplantation patients. The most common cause of death was infection followed by bleeding and malignancy, Among patients on CAPD, 10 patients had stepped CAPD because of peritonitis, hernia, ultrafiltration failure and CAPD leakage. Conclusion : In summary, there were no significant differences of clinical features, cumulative and technical survival between each renal replacement therapy in ADPKD patients. The most frequent reason for cessation of CAPD was peritonitis, The most common cause of death was infection in ESRD patients with ADPKD.

성인 신생검 1000례에 대한 분석

이성문,김현철,석 준,박용일,장국진,박관규,손철호,박성배,이태희 啓明大學校 醫科大學 1996 계명의대학술지 Vol.15 No.2

We performed 1,000 consecutive native kidney biopsies using the 14 gauge Franklin-modified Vim-Silverman needle in adults at Keimyung University Hospital between Dec. 1978 and Aug. 1994 to assess the knowledge regarding renal histology on patient management. The indications for renal biopsy were :nephrotic syndrome (61.1%), hematuria and proteinuria(17.1%), glomerulopathy associated with systemic diseases(11.2%), renal insufficiency(3.3%), acute glomerulonephritis(3.2%), acute renal failure(2.6%), uremia(1.0%) and rapidly progressive glomerulonephritis(0.5%). One core of renal was tissue obtained in 20.7% of the cases, 2 cores in 53.3% and above 3 cores in 26.0%. The tissue specimen was adequate for histological evaluation in 90.6% of the cases. The major glomerular diseases were minimal change nephrotic syndrome(27.8%), Ig A nephropa thy(17.3%), focal segmental glomerulosclerosis(10.6%), menbranous nephropathy(10.4%), lupus nephritis(8.1%), membranous proliferative glomerulonephritis(7.6%), chronic glomerulonephritis(3.5%) and crescentic glomerulopathy(1.5%). Complications occurred in 51.8% of the total biopsies performed, consisting of microscopic hematuria lasting for more than 12 hours(38.3%), gross hematuria(9.1%), pain and tenderness(5.8%) and perirenal hematoma(2.7%). Major complications occurred in 12 patients(1.2%) in whom active therapy was required. In 7 cases, active hemorrhage developed and transfusion was required. Surgical repair of laceration with persistent bleeding was required in two patients. Three patients developed arteriovenous arteriovenous fistula following renal biopsies, who were treated successfully with superselective embolization. We suggested that a percutaneous renal biopsy is necessary for optimal evaluation of the glomerular disease when it comes to patient management.

現下兒童 敎育課程이 國民保健 特히 成長發育에 미치는 影響에 關한 硏究 : <第1報> 1968年度 國民學校 6學年 兒童의 成長發育에 關한 硏究<Report Ⅰ> Study on the Growth and Development of 6th Grade Students of a Primary School in 1968

金基昌,孫撤,朴秉日,陳憲成,朴鍾甲,崔炳梓,尹鍾晩,金明源,朴玉圭,姜英俊,李泰熙 대한의학협회 1969 대한의학협회지 Vol.12 No.6