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박정,김용욱,김영한,정용갑,조남경,오승협,Park, Jeong,Kim, Yong-Wook,Kim, Young-Han,Chung, Yong-Gahp,Cho, Nam-Kyung,Oh, Seung-Hyub 대한기계학회 2000 大韓機械學會論文集B Vol.24 No.5
A model for depicting the rocket engine combustion process is presented and several experiments near a design point are provided with a FOOF type of unlike impinging injector for a propellant combination of Jet A-1 fuel and liquid-oxygen. The model is based on the assumption that the vaporization is the rate-controlling combustion process. The effects of initial drop size and initial drop velocity are systematically shown and discussed. It is seen that in the midst of considered parameters the change of initial drop size is more sensitive to the performance. The proposed model describes qualitative trends of combustion process well despite of its simplicity.
박환표(Hwan-Pyo Park),한재구(Jae-Goo Han),진경호(Kyung-Ho Chin) 대한설비공학회 2010 대한설비공학회 학술발표대회논문집 Vol.2010 No.6
Recently, international LNG plant construction markets are expending. However, international LNG plant construction projects are high risk and complicated. So, risk management based construction is needed. This research has drew the construction management factors and evaluate its decision weight to secured the technology of construction management in LNG plant EPC phases. And this research has suggested decision making support system to manage construction management considering decision making methodology in LNG Plant project.
DITI 진단을 통한 Bell`s palsy의 임상적 고찰
박경화,김종한,황충연,Park, Kyung-hwa,Kim, Jong-han,Hwang, Choong-yeon 대한한방안이비인후피부과학회 1998 한방안이비인후피부과학회지 Vol.11 No.1
The clinical data and thermographic imaging were analyzed on the 100 cases of Bell's palsy who were treated in the Kwang-Ju Oriental Medical Hospita! of Wonkwang University from February to October 1997. All the cases were taken Digital Infrared Thermograph Imaging(DITI) before treatment and 30 cases of them were taken follow up imaging again after recovery. And the following results were obtained. 1. Of 100 cases, under teenager occupied $1\%,\;teenager\;8\%,\;2nd\;decade\;14\%,\;3rd\;decade\;11\%,\;4th\;decade\;16\%,\;5th\;decade\;26\%,\;6th\;decade\;16\%,\;7th\;decade\;7\%\;and\;over\;80\;occupied\;1\%$. 2. Male occupied $48\%$ and female occupied $52\%$. 3. $42\%\;of\;male\;and\;23\%$ of female had the affected side at left side. And right facial nerve palsy occured at $29\%\;of\;male\;and\;29\%$ of female. 4. The most common cause of Bell's palsy was cold wind $18\%$, and the next were excessive labor $15\%,\;stress\;12\%,drinking\;2\%\;and\;cold\;food\;1\%$. 5. Thermal pattern were present as hyperthermal pattern in $44\%$ and hypothermal pattern in $22\%$. 6. The DITI showed hyperthermal pattern as close as to the onset day and changes to hypothermal pattern as times passed. 7. The DITI pattern and post-auricular pain, the most common prodomal syndrome, showed no significant relationship. 8. The relationship between the grade of paralysis and thermal patttern of DITI showed no significance. 9. Mean temperature of loci in affected side indicrtted $30.27^{\circ}C\;at\;Yang\;baek,\;30.02^{\circ}C\;at\;Taeyang,\;29.25^{\circ}C\;at\;Geoyo,\;29.62^{\circ}C\;at\;Jichang,\;29.78^{\circ}C\;at\;Hakwan,\;29.61^{\circ}C\;at\;Hyupgeo,\;and\;30.59^{\circ}C$at Yeopoong. 10. Mean temperature of loci in unaffected side showed $30.16^{\circ}C\;at\;Yang\;baek,\;30.02^{\circ}C\;at\;Taeyang,\;29.61^{\circ}C\;at\;Geoyo,\;29.68^{\circ}C\;at\;Jichang,\;29.70^{\circ}C\;at\;Hakwan,\;29.57^{\circ}C\;at\;Hyupgeo,\;and\;29.89^{\circ}C$at Yeopoong. 11. Of 30 cases who were taken follow up imaging again after recovery, the relationship between delta T at loci and symptoms showed no significance. It should be needed further investigation in order to apply them for clinical evaluation.
대전시 공공하수처리시설 유입수 수질자료의 통계적 특성 및 추계학적 모의
박기정 ( Gi Jung Park ),정민재 ( Min Jae Jung ),이한샘 ( Han Saem Lee ),김덕우 ( Deok Woo Kim ),윤재영 ( Jae Yong Yoon ),백경록 ( Kyung Rock Paik ) 한국물환경학회 2012 한국물환경학회지 Vol.28 No.1
In this study, we analyze statistical characteristics of influent water quality in Daejeon waste water treatment plant and apply a stochastic model for data generation. In the analysis, the influent water quality data from year 2003 to 2008, except for year 2006, are used. Among water quality variables, we find strong correlations between BOD and T-N; T-N and T-P; BOD and T-P; CODMn and T-P; and BOD and CODMn. We also find that different water quality variables follow different theoretical probability distribution functions, which also depends on whether the seasonal cycle is removed. Finally, we generate the influent water quality data using the multi-season 1st Markov model (Thomas-Fiering model). With model parameters calibrated for the period 2003~2005, the generated data for 2007~2008 are well compared with observed data showing good agreement in general. BOD and T-N are underestimated by the stochastic model. This is mainly due to the statistical difference in observed data itself between two periods of 2003~2005 and 2007~2008. Therefore, we expect the stochastic model can be applied with more confidence in the case that the data follows stationary pattern.
Doxorubicin에 과민반응을 보인 유방암 환자에서 성공적으로 시행한 Epirubicin 탈감작 요법
박한기 ( Han Ki Park ),김민혜 ( Min Hye Kim ),임경환 ( Kyung Whan Lim ),강민구 ( Min Koo Kang ),김병근 ( Byung Keun Kim ),김태완 ( Tae Wan Kim ),권재우 ( Jae Woo Kwon ),이소희 ( So Hee Lee ),이상민 ( Sang Min Lee ),김세훈 ( Se Hoo 대한천식알레르기학회 2009 천식 및 알레르기 Vol.29 No.2
Doxorubicin, a chemotherapeutic agent of the anthracycline family, has commonly been used to treat a wide range of cancers including leukemia, Hodgkin`s lymphoma, and cancers of the breast, uterus, ovary and bladder. Hypersensitivity is a rare adverse reaction to anthracyclines including daunorubicin, idarubicin and epirubicin. Although cross-reactivity among chemotherapeutic agents of the anthracycline family is not completely established, these agents are not clinically recommended if a patient has show hypersensitivity reaction to any anthracyclines. Desensitization is an alternative treatment option to overcome hypersensitivity reaction to anthracyclines, but cases of anthracycline desensitization have rarely been reported till now. We report successful epirubucin desensitization in a breast cancer patient with doxorubicin hypersensitivity. (Korean J Asthma Allergy Clin Immunol 2009;29:127-131)
빈안장증후군과 단안 제육뇌신경마비로 나타난 소아의 특발 두개내압상승
박신형(Shin Hyeong Park),이우혁(Woo Hyuk Lee),강태신(Tae Seen Kang),조현경(Hyun Kyung Cho),한용섭(Yong Seop Han),김지혜(Ji Hye Kim) 대한검안학회 2021 Annals of optometry and contact lens Vol.20 No.4
목적: 뇌자기공명영상검사에서 빈안장증후군이 동반된 양안의 시신경유두부종 및 단안의 제육뇌신경마비를 보이는 특발두개내압상승 환아를 경험하였기에 이를 보고하고자 한다. 증례요약: 9세 정상 체중 남자 환아가 4일 전 발생한 두통과 복시를 주소로 내원하였다. 교대프리즘가림검사에서 원거리 16프리즘디옵터의 내사시가 있었으며 안구운동검사에서 우안의 -1 외전장애가 있었다. 안저검사에서 심한 양안의 시신경유두부종 및 유두 경계부 출혈이 있었으며 시야검사에서 우안의 생리적 맹점 확대가 관찰되었다. 뇌자기공명영상에서 빈안장 및 후공막편평 등 뇌척수액압상승 소견들이 보여 특발두개내압상승을 진단하고 치료하였다. 치료 4달째 양안의 시신경유두부종과 유두 경계부 출혈은 호전되었고 우안의 외전장애도 호전되었다. 뇌자기공명영상에서 빈안장이 호전되었으며, 치료 8달째 재발 소견 없이 경과 관찰 중이다. 결론: 특발두개내압상승이 의심되는 환아가 내원하였으나 요추 천자검사를 하기 어려운 상황인 경우 뇌자기공명영상검사를 적극적으로 활용해야 하며, 뇌자기공명영상에서 이상이 발견된 경우 뇌자기공명영상검사가 이후 질병의 경과를 판단하는 데 도움을 줄 수 있다. Purpose: We report the case of a child with idiopathic intracranial hypertension who presented with binocular papillary edema and monocular sixth cranial nerve palsy accompanied by empty sella syndrome evident on brain magnetic resonance imaging. Case summary: A 9-year-old, normal-weight male patient visited the emergency room complaining of headache and diplopia 4 days in duration. The alternative prism cover test revealed esotropia of 16 prism diopters and a -1 right lateral gaze limitation. A fundus examination revealed papilledema and peripapillary hemorrhages in both eyes, and a visual field examination an enlarged, physiological blind spot in the right eye. Brain magnetic resonance imaging revealed elevated cerebrospinal fluid pressure, an empty sella, and posterior scleral flattening. We diagnosed and treated idiopathic intracranial hypertension. After 4 months, the papilledema and peripapillary hemorrhages of both eyes resolved, and the right lateral gaze limitation improved. The empty sella improved on brain magnetic resonance imaging, and we noted no recurrence 8 months after treatment. Conclusions: If a child with suspected idiopathic intracranial hypertension visits a hospital, but it is difficult to perform a lumbar puncture, brain magnetic resonance imaging should be scheduled. If abnormalities are found, these help to determine the course of disease.
생체외 류마토이드 관절염 실험 모델에서 청열사습탕(淸熱瀉濕湯)의 효과
박진상 ( Jin Sang Park ),한명금 ( Myeng Gum Han ),임양의 ( Yang Eui Lim ),이수경 ( Su Kyung Lee ),신병철 ( Byung Cheul Shin ),권영달 ( Young Dal Kwon ),송용선 ( Yung Sun Song ) 한방재활의학과학회 2004 한방재활의학과학회지 Vol.14 No.2
Objective: This study was designed to understand the mechanism of action of Cheongyeolsaseup-tang(Qingrexieshi-tang) (CYSST) leading to control of mast cells on inflammatory condition like RA. Methods: Viability of cells was evaluated by MTT colorimetric assay for 8 h incubation after stimulation of PMA plus A23187. HMC-1 cells (3×105 cells/㎖) were stimulated for 8 hour incubation with PMA plus A23187, we investigated the effect of CYSST on the production of cytokines by activated human mast cell line HMC-1. Results: When CYSST (1 mg/ml) was added, the production of tumor necrosis factor (TNF)-α, interleukin (IL)-6 was significantly inhibited by 37% and 33.6%, respectively in phorbol 12-myristate 13-acetate plus calcium ionophore A23187-stimulated HMC-1 cells. RA is an aggressive inflammatory disease in which chemokines are thought to recruit leukocytes and induce angiogenesis. CYSST also inhibited by 48% the production of IL-8 in HMC-1 cells. In addition, CYSST inhibited the expression of Nuclear factor-κB(NF-κB) in HMC-1 cells. Conclusions: When CYSST was added, the production of TNF-α, IL-6, IL-8 was significantly inhibited. These results imply that CYSST has a critical role on the treatment of the bone damage associated with rheumatoid arthritis.