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당뇨병환자에서 뇨증 Fibronectin농도의 증가에 관한 연구
한승범,조준승,손건영,서성문,박근용,조성래,박규영,박정모,이인규,여준기 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4
Plasma fibronectin is an α₂-glyoprotein, which is produced by vascular endothelial cells. Raised level of plasma fibronectin has been observed in diabetic patients particularly in the presence of microvascular complications. However, no available data exist about urine level of this glycoprotein in diabetic patients. We measured urine fibronectin level by ELISA methods in 54 diabetic patients who have microvascular comlications or not. The following results were obtained. 1) Urine fibronectin level(㎍/g creatinine) in diabetic group(1740.0±678.0) is increased compaired with those in normal control group(471.0±59.0). but this results were not significantly different among two groups(P>0.05). 2) Urine fibronectin level(㎍/g creatinine) was significantly increased in patients with nephropathy (6188.0±3144.0) compared with those in normal control group(471.0±59.0) and patients without nephropathy(645.0±251.0)(P<0.001). 3) There were a significant correlation between BUN, creatinine, creatinine clearance, 24hr urine total protein and urine fibronectin level in diabetic patients. Our data suggest that urine fibronectin excretion level might be used as a sensitive guide for diabectic nephropathy.
시멘트 및 고성능AE감수제가 고유동콘크리트의 유동특성에 미치는 효과에 관한 실험적 연구
박선규,반성수,우영제,김규용,김무한 忠南大學校 産業技術硏究所 1998 산업기술연구논문집 Vol.13 No.1
The fluidity of high flowing concrete can be affected by numerous parameters which characterize either the cement or the admixture. The reactivity of a cement as determined by its chemical compositions (especially its C₃A content), its fineness and its content in sulfates and alkalies obviously plays a key role in rheology of high flowing concrete in fresh state. Specific properties of high range water reducing AE agent used to enhance the workability of high flowing concrete also exert important influence. The purpose of this experimental study is to investigate and analyze the effect of cement and high range water reducing AE agent in fluidity, setting, compressive strength of high flowing concrete. As a result, we found that fluidity of high flowing concrete is affected greatly by kind of cement and high range water reducing AE agent, also, there is harmonic character between high belite cement and polycarbonic acid high range water reducing AE agent.
박정규,서동신,최한고 國立金烏工科大學校附設生産技術硏究所 1997 産業技術開發硏究 Vol.13 No.-
An adaptive equalizer in digital communication has been used to reduce intersymbol interference(ISI) and noise via radio and telephone channels. The problem of equalization can be viewed as a classification problem, which seeks to classify an observed channel output into one of the finite symbol points in the data. This paper presents the nonlinear adaptive equalizer using the modified recurrent neural networks(RNNs). The RNN structure used in this paper differs from Jordan's and Elman's RNNs with respect to feedback paths. Comparing with the conventional LMS and the feedforward neural network equalizers, the results of the RNN based equalizer show superier performance in terms of mean square error.
천연골재 및 재생골재콘크리트의 Na₂SO₄침식에 의한 화학저항성에 관한 실험적 연구
김규용,이정율,박유신,강석표,김무한 忠南大學校 産業技術硏究所 1998 산업기술연구논문집 Vol.13 No.1
Now a day, the more Proportion of concrete used in practice is exposed to serious chemical attack Chemical reactions that involve formation of expansive products in hardened concrete can lead to certain harmful effects. In this study, it is to compare and investigate the chemical resistance of natural and recycled aggregate concrete by attacked Na₂SO₄according to W/C ratio. The result of this study is that the chemical resistance of recycled aggregate concrete is lower than natural aggregate concrete. But it is developed the chemical resistance by decreasing the W/C ratio.
한경도,박용규,Han, Kyung-Do,Park, Yong-Gyu 한국데이터정보과학회 2012 한국데이터정보과학회지 Vol.23 No.1
두 평정자간 평가의 일치정도를 나타내는 합치도로 Cohen (1960)의 ${\pi}$, Scott (1955)의 H, 박미희와 박용규 (2007)의 등 많은 통계량이 제안되어왔다. 모의실험을 통하여 균형적 주변분포에서의 명목형과 순서형 합치도, 두 가지 역설이 발생하는 불균형 주변분포에서의 명목형 합치도들의 편의, 표준오차, 평균오차제곱 분산, 변이계수를 비교한 결과, 모든 경우에서 AC1과 H의 표준오차와 변이계수가 가장 작게 나타났다. Many statistics, such as Cohen's (1960) ${\kappa}$, Scott's (1955) ${\pi}$, and Park and Park's (2007) H have been proposed as measures of agreement to represent inter-rater reliability. This study compared bias, SE, MSE, and CV of the measures of agreement with nominal and ordinal categories in the balanced marginal distributions, and those with nominal categories in the two paradoxical situations. As a result, in all cases, AC1and Hhad smaller SE and CV.
이상주,이영모,이한규,최대은,박기현,이강욱,신영태 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2
Autosomal dominant polycystic kidney disease(ADPKD) is one of most common hereditary disorder. It is potentially fatal and the major mobilities are hypertension and renal failure. To elucidate clinical characteristics and outcomes of ADPKD, 67 ADPKD patients were analyzed retrospectively. The male to female ratio was 48 years for males and 42 years for females. The factors leading to the dignosis of ADPKD were flank or abdominal pain (46%), palpable abdominal mass (24%), incidental findings (18%), gross hematuria and headache. Urinalysis result showed hematuria (31%), proteinuria (19%), pyuria (18%). Among renal complications hypertension (67%) was the most common. Other complications were urolithiasis (16%) upper urinary tract infection (9%), cyst infection (7%). Azotemia was observed in 24% of cases. Echocardiography showed left ventricular hypertrophy in 24% and valvular regurgitation in 18% of cases, but there was no mital valve prolapse. Cerebrovascular events occurred in 6 cases (2 cases of intervertebral hemorrhage and 4 cases of cerebral infarction). Hipatic cyst were observed in 64% of cases. Eighteen cases culminated in end stage renal failure (ESRF) at an of 47. According to this study, the most common complications of ADPKD was hypertension (67%), ESRF (27%), and cerebrovascular event (9%). Hypertension was more frequently observed in increased creatinine group than normal.
최민호,이계복,조규원,박진영,김경수,송정석,한종현 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1
The purpose of this study is to measure the changes of regional cerebral blood flow (rCBF) and blood pressure (BP) of Cortex Acanthopanacis in rats, and to determine the effect of Cortex Acanthopanacis on phenylephrine (PE) induced contraction of isolated rat thoracic aorts. The measurement was continually monitored by laser-doppler flowmeter (Transonic Instrument, USA) and pressure transducer (Grass, USA) in anesthetized adult Sprague-Dawley rats through the data acquisition system composed of MacLab and Macintosh computer. Contractile force was measured with force displacement transducer under 1.5 g loading tension. The result of this experiment was as following; 1. Cortex Acanthopanacis did not effect the changes of rCBF and blood pressure significantly. 2. Contractions evoked by phenylephrine were decreased significantly by Cortex Acanthopanacis 3. L-NNA, ODQ, atropine and indomethacin significantly altered the relaxation of Cortex Acanthopanacis. 4. Propranolol did not change the relaxation of Cortex Acanthopanacis. These results indicate that Cortex Acanthopanacis did not change the rCBF and BP, but Cortex Acanthopanacis can relax PE induced contraction of isolated rat thoracic aorta and that this increasing contraction related to endothelium and various mechanism.