한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

Aflatoxin-DNA Adduct의 화학합성에 관한 연구

최상경,김성영,강진순,정덕화 경상대학교 유전공학연구소 1993 遺傳工學硏究所報 Vol.12 No.-

Aflatoxin은 세계 여러 곳에서 식품에 오염되어 발견되며 증가하는 인간의 간암발생과 빈번히 역학적으로 관련하여 보고되는 발암물질이다. 이러한 aflatoxin의 발암성 규명에 대한 연구의 일환으로 20㎎ calf thymus DNA와 8㎎ 표준 aflatoxin B₁을 반응시켜 화학적으로 aflatoxin B₁-DNA adduct를 합성하였다. 합성된 aflatoxin B₁-DNA adduct는 산가수분해와 열처리에 의해 거대한 DNA 분자를 절단하였고, immunoaffinity column을 통과시켜 aflatoxin B₁-DNA adduct만 선택적으로 정제한 후 HPLC법으로 정량하였다. 그 결과 반응생성물의 대부분은 aflatoxin B₁-guanine adduct였으며, 그 함량은 aflatoxin B₁으로 5.2㎎이었다. Aflatoxins are highly carcinogenic agents consistantly found as contaminants in human food supplies in many areas of the world and epidemiologically linked to incidence of human liver cancer. To examine the carcinogenic action of aflatoxin B₁,aflatoxin B₁-DNA adducts were chemically synhtesized with the reaction of 20㎎ calf thymus DNA, and 8㎎ standard aflatoxin B₁. Since DNA molecule was too large for analysis, it was fragmented by acid hydrolysis and heat. The fragmented aflatoxin B₁-DNA adducts were selectively concentrated by immunoaffinity column procedure and confirmed by HPLC method. The main component was aflatoxin B₁-guanine adduct, which was quantatively measured as 5.2㎎ aflatoxin B₁.

Tomatotone과 Gibberellin(GA3)의 處理가 輸出用 가지(Solanum melongena. L)의 生育 및 收量에 미치는 影響

최성관,이재필,진동호,오주성,박흥식,정순재 동아대학교 농업생명과학연구소 2001 農業生命資援硏究 Vol.10 No.1

These grafting seeding "Torobambica", rootstock "Jang Ja" and "Chuk Yang" were tested to investigate the differences between the growth of eggplants and the number of eggplants which can be influenced by the growth retardant aerosol. For the test of the growth retardant aerosol, the flower clusters were sprayed with one hundred units of Tomatotone liquid and with three hundred units of GA3 on the day they flowered and sprayed two or three days before flowering. The results were as follows: 1.According to the growth retardant aerosol of Tomatotone, the plant height was the tallest at 226.21 cm with foliar spray and the high Marketable fruit was good at the percent of 77.38 with a flowering spray and Tomatotone on the day they flowered. 2.According to the growth retardant aerosol of GA3, the plant's height was the tallest at 229.27cm with foliage which was sprayed every week. The high quality fruit was good at the percent of 69.11 with a flowering spray and GA3 on the day they flowered. 3.According to Tomatotone and GA3 treatments of the plant growth regulators, the plant's height was the tallest sprayed every week and the high Marketable fruit was good at the flowering spray and Tomatotone on the day they flowered. and Yield per 10a was good at the flowering spray and Tomatotone on the day they flowered.

강릉 옥계지역 田자집의 공간구성 변화실태와 효과적인 개량방법 모색에 관한 연구

최장순,이상범 대한건축학회 2004 대한건축학회논문집 Vol.20 No.10

The two villages, Jungchon and Shinchon, at Okgye in Gangneung area are consisted of 田-shaped houses in the past But the dwelling space of the 田-shaped houses was changed to pursue the convenience and function by the modernization policy of the government authorities The purpose of this study is aimed at grasping how the spatial transformations of 田-shaped houses by the modernization and urbanization have been coped with and changed. The results are as follows The maintenance or removal of wall, the fuel change of heating and cooking, the leveling change of kitchen floor and so on made possible the standing life. And its plan was changed from two row room which was made by climatic confrontation to one row room by removal of wall lying between front room and back room, the fuel change of heating, the change of heating method and the heat insulating material. The roof material was changed from the traditional roof material such as a rice straw, wood tile and the bark of an acorn tree to the modern roof material such as a corrugated sheet iron or corrugated asbestos-cement sheet. And the structure of cement brick or block was attached to the traditional wood structure because of the easiness of execution

솔잎(갈비)·솔방울의 수처리에 관한 연구

최순규,엄기수,성현순,김윤영,이시우,정대일,이용균 동아대학교 환경문제연구소 1994 硏究報告 Vol.17 No.2

The absorption ability of low density heavy metal of pine needles and cones is better than one of existing absorption materials in treatment ability and experimental condition. The elimination ability of chlorine of pine needles and cones is better than one of active carbon. In elimination of trihalomethane, the effect of treatment of pine needles is lower than one of pine cones. And surface of pine needles and cones after absorption of heavy metal ion was observed by Scanning Electron Microscope(SEM). Application and availability of pine needles and cones as absorption material need lots of experiments. The experiment on Gal-Bi(fallen leaves) is proceeding.

두경부 편평세포암종에서 치료 실패와 제 17번 다염색체 소견의 의의

채성원,최건,최종욱,정광윤,김용환,황순재 대한이비인후과학회 1998 대한이비인후과학회지 두경부외과학 Vol.41 No.5

Methotrexate 치료를 받고 있는 활동성 류마티스 관절염 환자에서 etanercept의 유효성과 안전성에 관한 연구

최병렬,강태영,정청일,이혜순,엄완식,김태환,전재범,유대현,배상철 대한내과학회 2004 대한내과학회지 Vol.66 No.5

목적 : 류마티스 관절염을 앓고 있는 한국인 중에 기존 DMARDs로 치료 실패하였고, 고정용량의 MTX를 복용하고 있는 환자들에 있어서 etanercept의 유효성과 안전성을 평가하고자 하였다. 방법 : 기존 DMARDs로 치료 실패한 활동성 류마티스 관절염 환자 76명을 대상으로 하여 단일군, 공개시험을 하였다. 대상 환자들은 고정용량의 MTX를 복용하면서 etanercept 25 mg을 1주일에 두 번 피하 주사하였으며 12주간 투여하였다. 유효성은 ACR 20, ACR 50,조조강직 시간으로 평가하였고, 약제의 안전성은 이상반응 등으로 평가하였다. 결과 : 대상 환자는 총 76명으로 평균 연령은 45.2세, 남자 5명, 여자 71명이었다. 84.4%인 54명이 12주째에 ACR 20을 만족하였고, 53.1%인 34명이 12주째에 ACR 50을 만족하였다. 조조 강직 시간은 치료 전 203.3분에서 치료 12주째 42.6분을 평균 74.5% 호전되었다. 가장 흔한 이상반응은 주사부위 반응이었다. 이외에도 상기도 감염, 오심, 안면부종 등이 발생하였으나 심각한 부작용은 없었다. 결론 : etanercept는 효과적이고, 안전한 류마티스 관절염 치료 방법이며 특히 MTX치료에도 불구하고 활동성인 류마티스 관절염에 기대되는 치료라고 할 수 있다. Background : This study was performed to investigate the efficacy and safety of etanercept in active rheumatoid arthritis patients with stable dose of methotrexate in Korean. Methods : In a 12 week, single arm, open trial, we assigned 76 patients with active rheumatoid arthritis who had an inadequate response to disease-modifying antirheumatic drugs. Patients received twice-weekly subcutaneous injections of etanercept 25 ㎎ while containing to receive methotrexate at a stable dose of 7.5~25 ㎎ per week. The clinical response was defined as the percent improvement in disease activity according to the criteria of the American Collage of Rheumatology (ACR) at 12 weeks. Results : Etanrecept led to significant improvements in disease activity and was safe and well tolerated. At 12 week, 84.4% of the patients receiving 25 ㎎ of etanercept achieved a 20% ACR response, and 53.1% of those receiving etanercept achieved a 50% ACR response. The most common adverse event was injection-site reaction. Other advanse events were upper respiratory infection, nausea, and facial edema, but there were no serious adverse events associated with etanercept. Conclusion : In active rheumatoid arthritis patients, etanercept was safe, well tolerated, and provided rapid clinical improvements.

영상처리를 위한 범용성과 지능성을 갖는 병렬 처리기 구조

백순흠,박종원,최성혁 공주영상정보대학 2000 논문집 Vol.7 No.-

운용 측면에서 병렬 처리 방법을 SIMD 구조와 Semi-MIMD 구조를 적용할 수 있도록 하여 병렬 처리 프로그램 작성의 용이성과 적용 대상 범위를 증대시켜 사용자로 하여금 병렬 처리 알고리즘을 제안한 병렬 처리기를 이용하여 구현 시에 편의성을 제고하였다. 성능 개선 측면에서 영상 데이터를 처리하는 과정에서 많이 적용되는 Matrix 연산을 적용 예로 하며 일반적인 직렬 처리 계산 과정과 제안한 병렬 처리기 계산 과정을 비교한 결과, 계산 결과가 일치하였고 성능면에서는 2배의 성능 개선 효과를 얻을 수 있었다. 2배의 성능 개선 효과는 병렬 처리기의 처리기가 4개인 경우이므로, 처리기의 개수가 증가하면 증가된 개수에 따라 그 성능 개선 폭은 더욱 증대될 것이다.

제1요수 불완전 하반신 마비 환자에서의 기능적 전기자극에 의한 훈련 증례보고

최현주,이수영,김종문,강선화,정순열,강곤,정진상 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

Functional electrical stimulation(FES) is known to increase muscle bulk and strength and prevent muscle atrophy in complete paraplegic patients. And other benefits include peripheral adaptations which improve muscle endurance, girth, and appearance, as well as central circulatory adaptation which enhances aerobic(cardiopulmonary) capacity. Good candidates for FES include spinal cord injured patients who have clinically complete upper motor neuron lesion between T4-T12. But we experienced incomplete L1 paraplegic patient who has improved maximal knee extension power, endurance, circumference and cross-sectional area of the thigh and the shank after FES-induced exercise for 44 weeks. So we recommend more trial of the FES-induced exercise to not only complete but also incomplete lumbar paraplegic patients.

열역학 실험식에 의한 Cd-Zn계의 안정 및 준안정 상태도의 계산

崔舜惇,權海旭,金星秀 嶺南大學校 工業技術硏究所 1986 연구보고 Vol.14 No.2

For quantitative predictions of the metastable features and the compact expression of phase equilibria encountered in the extractive metallurgy of cadmium and zine, the calculations of stable and metastable equilibrium diagrams of the Cd-Zn system are made using the four parameter subregular solution model. Parameters of the thermodynamic functions are derived from the phase diagram data of "Bulletin of Alloy Phase Diagrams" and the enthalpy data of Wittig and Kleppa. Stable equilibrium diagram and thermodynamic quantities re-calculated from the optimized parameters agree with all the experimental data within the errors. Such metastable phase equilibria as the chemical spinodals, the locus of compositions and temperature where the Gibbs energies of the liquid and solid are equal(To), the metastable extensions of the solidus and liquidus curves, and metastable miscibility gaps. Excellent agreement of the calculated solvus boundary data with the experimental data is believed to provide a correct expectation of the metastable phase equilibria.