비고령 성인환자의 만성폐쇄성폐질환 약물사용 현황과 영향인자

문채원,나현오,이정연 한국임상약학회 2016 한국임상약학회지 Vol.26 No.4

Background: This study is to investigate the prescription patterns and factors related to the number of medications treating chronic obstructive pulmonary disease (COPD) in patients under 65 years old according to GOLD guidelines. Methods: We retrospectively analyzed the medical records of patients aged 40-64 years with a diagnosis of COPD from January to March 2016. Patients were classified by combined assessment of COPD (grades A, B, C, D) using spirometry, exacerbation history, mMRC, and/or CAT results. We analyzed prescribed medications, treatment options and factors related to the numbers of COPD medications. Results: The total number of prescriptions were 251. About 35.5% of patients were classified as GOLD A, 34.2% as GOLD B, 17.1% as GOLD C and 13.2% as GOLD D. Inhaled bronchodilator was prescribed for 86.9% of patients and the most frequent COPD medication was longacting muscarinic antagonist (LAMA) followed by inhaled corticosteroids/long acting beta agonist (ICS/LABA). The majority of low risk patients (GOLD A/B) were prescribed a monotherapy with LAMA or LABA. For high risk patients (GOLD C/D), combination treatment with ICS+LAMA+LABA was mostly prescribed. The 21.2% of patients in GOLD D received systemic corticosteroid. The average number of medications per prescription was 3.7, and this number increased with increasing COPD grade, COPD duration and lung function reduction (FEV1, FEV1/FVC). Conclusion: Generally high adherence to GOLD guideline recommendations was reported. Given the progressive nature of the disease, results suggest that closer attention to respiratory symptoms for early detection, diagnosis, and appropriate treatment of COPD is warranted.

만성폐쇄성폐질환 환자에서 흡입제 Indacaterol과Tiotropium의 효과 평가

문채원,안혜림,최선,김순주,황보신이,나현오 한국병원약사회 2018 병원약사회지 Vol.35 No.1

According to current Global initiative for chronic Obstructive Lung Disease (GOLD) strategy, longacting inhaled bronchodilators for treating stable chronic obstructive pulmonary disease (COPD) use two classes of pharmacological agents: long-acting β2-agonist (LABA; eg, Indacaterol) and long-acting muscarinic antagonists (LAMA; eg, Tiotropium). The objective of this study was to assess the long-term effect of Indacaterol, including its efficacy on exacerbations and adverse events for patients with severe COPD compared to Tiotropium. Data were retrospectively collected from COPD patients who visited a respiratory medicine clinic of Seoul St. Mary's Hospital from April 2013 to August 2015 when Indacaterol was introduced. They used LABA (Indacaterol) or LAMA (Tiotropium) alone for more than one year. After 52 weeks of treatment, lung function (forced expiratory volume in 1 second; FEV1), incidence of COPD worsening (add antibiotics or steroids, hospitalization), and adverse events were measured as outcomes. Between April 2013 and August 2015, 136 patients were collected (75 with Indacaterol and 61 with Tiotropium). At week 52, estimated least squares mean trough FEV1 in both groups were increased (Indacaterol: 0.11 L, p 0.0001; Tiotropium: 0.19 L, p 0.0001), showing no significant difference between the two groups. Sub-analysis results on Exsmokers revealed that FEV1 was increased significantly in both groups. However, in smokers, the increase of FEV1 was not statistically significant. Indacaterol did not show non-inferiority in terms of annualized exacerbation rates: 0.35 (Indacaterol) versus 0.46 (Tiotropium); relative ratio of 0.76. Regarding safety results, the incidence of adverse events was higher in the Tiotropium group than that in the Indacaterol group (50.00% vs. 27.78%, p=0.0023). The most common adverse event was cough in the Indacaterol group, while dry mouth and BPH symptoms were the most common in the Tiotropium group. There was no superiority or inferiority in therapeutic effect between the two drugs after long-term use. Therefore, clinical pharmacists should consider side effects of the drug and encourage smoking cessation. Continuous monitoring is required for patients with COPD.

ZNS SSD 에서 F2FS 체크포인트 I/O 병렬화를 통한 대용량 파일에 대한 쓰기 성능 개선

문채원(Chaewon Moon),황인휘(Inhwi Hwang),염헌영(Heonyoung Yeom) 한국정보과학회 2023 한국정보과학회 학술발표논문집 Vol.2023 No.12

고민감도 병원성 박테리아의 검출을 위한 생체물질 기반 interior hotspot 제작

이수현,문채원,박성규 한국표면공학회 2023 한국표면공학회 학술발표회 초록집 Vol.2023 No.5

비대면 수업을 경험한 간호대학생의 대학생활 스트레스 및 스트레스 대처방식이 대학생활적응에 미치는 영향

정다영,손한울,임윤희,문채원,이해윤,오유경,김민채,김주이 한국산학기술학회 2022 한국산학기술학회논문지 Vol.23 No.12

This study investigated the effects of college life stress and stress-coping methods on student adaptation. The subjects were 232 nursing students who had experienced non-face-to-face classes. The research tools applied were a revised life stress scale for college students, the stress coping method scale, and a student adaptation to college questionnaire. Data were analyzed by descriptive statistics, t-test, ANOVA analysis, correlation analysis, and multiple regression analysis. Our results revealed that college life stress was negatively correlated to coping with stress (r=-.15, p=.020) and student adaptation to college (r=-.67, p<.001). However, stress-coping methods and student adaptation to college (r=.19, p=.002) showed a positive correlation. The variables imparting a significant effect on college life adjustment are future problems (t=-4.33, p<.001), value problems (t=-2.57, p=.011), and academic problems (t=-3.63, p<.001). These variables explained 52.5 % of the total change in the score for student adaptation to college. We determined that students who are worried about future problems, have entered the school without establishing a strong personal value, and are struggling with academic problems will require more attention and organizational intervention than in a non-face-to-face situation. 본 연구의 목적은 비대면 수업을 경험한 간호대학생의 대학생활 스트레스 및 스트레스 대처방식이 대학생활적응에 미치는 영향을 파악하고 간호대학생의 대학생활적응을 향상시킬 수 있는 방법을 제시하는 데 있다. 본 연구는 조사연구로 경기도 소재 A 대학의 간호대학생을 대상으로 2022년 6월 13일부터 15일까지 온라인 설문을 진행하여 수집된232명의 자료를 분석하였다. 연구 도구는 대학생활 스트레스 척도, 스트레스 대처방식 척도, 대학생활적응 척도를 사용하였으며 자료분석을 위해서는 기술통계, t-test, ANOVA 분석, 상관관계분석 및 다중회귀분석을 사용하였다. 총 232명의 자료를 분석했으며 그 결과 대학생활 스트레스와 스트레스 대처방식(r=-.15, p=.020) 및 대학생활적응(r=-.67, p<.001)은 음의 상관관계를, 스트레스 대처방식과 대학생활적응(r=.19, p=.002)은 양의 상관관계를 나타냈다. 대학생활적응에 유의한 영향을 미치는 변수는 대학생활 스트레스 하위요소 중 장래문제(t=-4.33, p<.001), 가치관문제(t=-2.57, p=.011), 학업문제(t=-3.63, p<.001)로 확인되었으며 이는 대학생활적응 점수 총변화량의 52.5 %를 설명하였다. 장래문제에 대해 고민하는 학생, 개인의 확고한 가치관을 확립하지 못한 학생, 학업문제로 힘들어하는 학생은 소통이 감소한비대면 상황에서 보다 더 많은 관심이 필요하며 이들의 적응을 돕기 위해서는 개인뿐 아닌 조직 차원의 관심과 중재가이루어져야 할 것이다.

공기 중 석면정도관리 시료 분석법 교육전․후 분석자의 정확도와 정밀도 평가

김민영,김나현,김범진,문채원,박채연,박치영,장봉기 순천향대학교 기초과학연구소 2023 순천향자연과학연구 논문집 Vol.29 No.1,2

To increase the accuracy and precision of asbestos analysis, this study used a phase contrast microscope to count the number of asbestos fibers in the air and compare the results of the analysis's asbestos fiber count before and after the training to find out whether the training conducted in this study could improve the accuracy and precision of the analyst. Six samples of asbestos quality control in the air from the Korea Occupational Safety and Health Agency were pretreated using the acetone-triacetin method, and then asbestos fibers were counted. After that, changes in accuracy and precision were paired t-test using the R program. In order to confirm the change in accuracy for each analyst, the change in difference from the reference value before and after training was analyzed using a paired t-test. As a result, analysts A, B, and D had statistically significantly increased accuracy. The result of averaging the difference from the reference value before and after training by sample and then paired t-testing all analysts into groups showed that the p-value was 0.0044, which significantly increased accuracy. As a result of paired t-testing the relative standard deviation (RSD) before and after training to confirm the change in precision for each analyst, only analyst A had significantly increased precision, but when the relative standard deviation of all analysts was grouped into groups, the p-value was 0.001, and the precision was significantly increased. From the above results, asbestos analysis training helped improve the accuracy of analysts and the precision of the analyst group, but did not significantly improve individual precision. Since the analysis was conducted with a small number of samples, it is believed that in order to increase the effectiveness of education, the number of samples should be increased and supplemented. In addition, only two samples (6.7%) out of 30 samples before the analyst training were found to be below the appropriate range, and all samples after training were found to be within the appropriate range. This is believed to be the result of the wide range of suitable samples currently being implemented and little difference in concentration, and it is believed that the appropriate range of the quality control sample should be adjusted or the sample should be divided into low and high concentrations to give discrimination power.

다학제 중환자 팀의료에서의 중환자약료 담당약사 역할에 대한 중요도 및 수행도 평가 설문연구 : 국내 임상의 및 약사 측면

손유민,이혜령,박은정,최은영,문채원,송영주,허은정,사은영,류수현,정선미,이경아,최은정,민명숙,김정미,김은영 한국병원약사회 2022 병원약사회지 Vol.39 No.4

Background : The objective of this study was to survey critical care pharmacists’ role by importance- performance analysis in multidisciplinary ICU teams. Methods : This multicenter prospective cross-sectional questionnaire study was conducted through direct mailing. Questionnaires and return envelopes were mailed to heads of hospital department of pharmacy. These questionnaires were designed to request for importance, performance of fundamental, desirable, and optimal services of pharmacy services for ICU pharmacists and satisfaction for clinicians. Data were subjected to importance-performance analysis. Results : Forty-one item pharmacy questionnaires and 25-item for clinicians were developed and distributed to ICU pharmacist and clinicians. Forty-seven (90%) pharmacists and 51 (66%) clinicians returned questionnaires. Clinicians generally rated satisfaction of pharmacy services more favorably than pharmacists in clinical function in both patient care and non-patient care. Means ± standard deviations (SDs) of importance and performance were 6.20±0.17 and 5.37±0.38, respectively, for the evaluation of clinical activities of patient-care by critical care pharmacist. In the case of pharmacists’ evaluation of non-patient care, means ± SDs of importance and performance were 4.86±0.70 and 4.78±0.21, respectively. The evaluation of importance for non-patient care tasks was significantly lower than that of patient-care tasks (p=0.001). The IPA analysis of clinician’s scores of importance and performance were 6.27±0.25 and 6.11±0.21, respectively for the evaluation of clinical activities of patient-care by critical care pharmacist. In the case of clinician’s evaluation of clinical activities of non-patient care, means ± SDs of importance and performance were 5.49±0.45 and 5.74±0.27, respectively. Conclusion : In conclusion, it was evaluated as important or appropriate performance and highly evaluated for satisfaction with the clinicians for critical care pharmacists’ role on importance- performance in ICU multidisciplinary team activity.

‘전인교육’ 용어에 내포된 ‘교육’ 개념의 해체

최성욱,김영진,김민정,문채원,최아영 한국교육원리학회 2020 교육원리연구 Vol.25 No.1

Communication with respect to education is based on a reasonable understanding and the use of appropriate terms. Existing educational research does not meet these two basic premises. Rather, the present educational research is mired in errors that degrade education to the level of common sense, confuse it with non-educational facts, or turn it into a simple function. As a result, the longer the research continues, the further away it becomes from the reality of education and the result of covering up education. ‘Education,’ which is contained in the term ‘education of the whole person,’ is no exception. To realize the elegant ideal of ‘education of the whole person,’ it is necessary to grasp the proper meaning of education as well as the concept of the whole person. However, the existing discussion on ‘education of the whole person’ has failed to meet expectations due to confusion in concepts and poor use of terminology. The study believed that the cause was misguided views of education and analyzed them from a critical perspective. It also carried out the work of correcting the term to the contextual meaning referred to in ‘education of the whole person.’ Through this, it is expected to contribute to eliminating obstacles to communication on ‘education of the whole person.’

의료기관 내 영상의학 검사 장비의 표면 오염도 분석 연구

이신우(Shin-Woo Lee),김다은(Da-eun Kim),문채원(Chae-won Mun),김갑중(Gap-Jung Kim),김상하(Sang-Ha Kim),박혜미(Hye-mi Park),유세종(Se-Jong Yoo) 한국방사선학회 2024 한국방사선학회 논문지 Vol.18 No.2

본 연구에서는 대전지역 종합병원 중 일반촬영장치, CT, MRI 검사 장치 각 2대씩 선정하여 시간대 별 검사 장치의 표면오염도를 측정하여 감염도를 예측하고 감염 예방을 위한 기초자료로 활용하고자 실험을 하였다. 그 결과 일반촬영장치와 MRI 검사장치의 시간대 별 표면 오염도는 13시>8시>16시 순이였으며, CT검사 장치는 13시>16시>8시 순이었으며 이는 검사 건수의 영향으로 나타났다. 또한 검사 장치 부위 별 표면 오염도 결과는 일반촬영장치는 Stand Bucky 손잡이, CT 검사장치는 머리받침대, MRI 검사 장치는 조작 스위치에서 ATP 오염도 수치가 가장 많이 나왔으며, 이는 접촉 건수와 밀접한 관계가 있었다. 소독 전후를 비교한 결과 소독 후 모든 장치에서 유의한 차이로 감소한 결과를 보였다. 실험 결과를 바탕으로 영상의학과 검사실의 오염도를 파악하고 감염질환을 예방할 수 있는 기초자료가 될 수 있을 것이라고 사료된다. In this study, two general X-ray device, CT, and MRI inspection devices were selected from general hospitals in the Daejeon area and an experiment was conducted to predict the level of infection by measuring the surface contamination of the inspection devices at different times and to use it as basic data for infection prevention. As a result, the surface contamination level by time zone for general X-ray devices and MRI examination devices was in the order of 13H > 8H > 16H, and for CT examination devices, it was 13H > 16H > 8H, which appeared to be influenced by the number of tests. In addition, the surface contamination results for each part of the test device showed that the highest ATP contamination value was found on the stand bucky handle for the general X-ray device, the headrest for the CT examination device, and the operation switch for the MRI examination device, which was closely related to the number of contacts. As a result of comparing before and after disinfection, all devices showed a significant decrease after disinfection. Based on the results of the experiment, it is believed that it can be used as basic data to identify the level of contamination in radiology laboratories and prevent infectious diseases.