HPLC를 사용한 쌀 중 잔류농약 동시분석법

최재천,이영자,김소희,최수영,최희주,정성욱,박흥재,김우성 한국환경과학회 2005 한국환경과학회지 Vol.14 No.4

A simple and sensitive analytical method based on RP-HPLC with UV detector(225 nm) and mobile phases using 0.1% phosphoric acid and acetonitrile was developed for simultaneous determination of quinclorac, bentazone, 2,4-D, bensulfuron-methyl, dymuron, capropamide, pencycuron, ethofenprox. This method was resulted in recovery of 78~ 96% with RSD 3.3~7.5%. LODs 0.12~0.84 and LOQs 0.34~1.20 ㎎/L. Calibration curves were linear with r of 0.9995~ 0.9999.

전국 10개 종합병원 중환자실 환자의 직장내 Vancomycin-resistant Enterococci(VRE) 보균율, 보균의 위험요인 및 유전적 다양성 조사

정희진,송준영,엄중식,김우주,최선주,최정현,이혁,정문현,이광미,신동현,손보라,최종성,우흥정,권정아,이경원,최강원,박승철 대한감염학회 2002 감염 Vol.34 No.5

프로토콜 분석을 통한 창의적 디자인 전략으로서의 은유와 유추

최한희(Choi, Han_Hee),주서령(Ju, Seo Ryeung),김미정(Kim, Mi Jeong) 한국실내디자인학회 2013 한국실내디자인학회논문집 Vol.22 No.1

The aim of this research is to explore the potential of analogy and metaphor as design strategies for supporting the creative design thinking. For the empirical research on analogical and metaphoric process in designing, we conducted design experiments that consist of three different conditions of given items as stimulation for design inspiration: baseline, surrealist paintings, and housing design collections. The results were analyzed using a protocol analysis in order to obtain more systmatic interpretation of the design processes and strategies. As a result, it was noted that students are more apt to read visual information rather than semantic information in the given items. Instead of the representation of their senses or feelings from the paintings, they visualized the analogical images of the paintings for the design representation. However, analogical and metaphoric thinking derived from the given items seem change a designer’s perspective, thus bring a novel interpretation on design problems, and eventually more creative and meaningful design ideas. An extended research using one-semester training and observation of the design studio process is introduced as a follow-up study for this paper. This research will investigate the long-term effect of the analogy and metaphor on the design thinking.

아버지의 양육 참여행동과 아동의 친사회적 도덕판단능력

정현희(Hyean Hee Jeong),최경순(Kyoung Soon Choi) 한국아동학회 1992 아동학회지 Vol.13 No.1

The purposes of this study are to investigate (1) the father`s child-rearing behavior perceived by children in relation to children`s sex, family type and mother`s job. (2) children`s prosocial moral judgement as related to children`s sex, family type, and mother`s job, and (3) the effect of fathers child-rearing behavior on children`s prosocial moral judgement. The subjects were 432 5th-6th grade elementary school children in Pusan. For the measurement of father`s child-rearing behavior, this researcher developed a father`s child-rearing behavior questionnaire based on Choi`s (1991) questionnaire. For the children`s prosocial moral judgement, the 4 prosocial moral dilemma by Eisenberg-Berg was used. The major findings were as follows. No significant results were found in relation to father`s child-rearing behavior and child`s sex, family type, and mother`s work status. Children`s prosocial behavior was not related to any of the above variables. Significant relationships were found between father`s child-rearing behavior and children`s prosocial moral judgement.

혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

glpD and glpE 유전자의 조절영역 결손변이주기가 전사조절에 미치는 영향

정희태,정수열,최용락 東亞大學校附設遺傳工學硏究所 1996 遺傳工學硏究 Vol.- No.3

glpD와 glpE는 같은 조절 영역 하에서 121 bp 간격을 두고 역방향으로 전사되어지며, 이들 유전자 상류영역에 존재하는 하나의 CRP binding site가 두 유전자의 전사 조절에 관여함을 이미 여러 연구를 통하여 확인되어졌다. 본 연구에서는 glpD와 glpE의 조절영역이 다양한 크기로 결손된 변이주를 작성하였다. 각 변이된 promoter의 발현조절 영향을 보고자 LacZ와의 융합 plasmid를 작성하였고, β-galactosidase 활성을 측정하여 cAMP에 의한 발현조절을 검토하였다. 발현조절 특성을 확인한 결과 CRP binding site 전까지 결손이 된 변이주는 wild와 비슷한 활성이지만 CRP bin-ding site가 없어진 변이주의 경우는 promoter 활성이 크게 감소했고 cAMP에 의한 발현조절은 나타내지 않았다. 한편 CRP의 공통배열을 삽입시키면 회복이 가능하였다. glpE의 조절영역도 glpD와 마찬가지로 다양하게 결손시킨 변이주를 작성하여 promoter 조절활성을 확인한 결과 CRP binding site가 없어진 변이주의 경우는 promoter 활성이 크게 감소하였으며, 결손된 CRP 결합영역을 삽입시키니 cAMP에 의한 전사촉진이 거의 회복되어졌다. The glpD gene encoding gly-3-p dehydrogenase is essential for the aerobic growth of E. coli on glycerol or gly-3-p. The glpE gene, the function of which is unknown, is transcribed divergently with respect to glpD gene. Expression of the adjacent but divergently transcribed glpD and glpE genes is positively regulated by the cAMP-CRP complex. In this study, for a precise investigation of the functional elements in the regulatory region for transcription activation by cAMP-CRP, deletion mutation have been introducted into the regulatory region. The effect of the deletion mutant on transcriptional regulation was tested in vivo by β-galctosidase activity. Deletion mutants in the regulatory region of glpD demonstrated that the presence of the CRP-binding site resulted in an sixfold increase in promoter activity. And also deletion mutants of glpE gene demonstrated that the presence of the CRP-binding site resulted in an eightfold increase in promoter activity. Insertion of 22 bp oligomer in the deletion mutants has shown that the CRP binding site is need for maximal expression of glpD and glpE genes.

K대학 여대생을 대상으로 한 치아우식활성검사 비교조사 연구

최은미,송윤신,장희경,최정이 경복대학 2002 京福論叢 Vol.6 No.-

본 연구는 치아우식증 발생요인 중 타액요인을 집중적으로 분석하고자 타액분비율, 타액점조도, 타액완충능, 스나이더, 구강내 포도당잔류검사를 조사하였으며, 특히 20내 남성의 치아우식증 발생요인에 대한 연구자료와 타액분비율과 타액내 pH 변화에 대한 조사 및 스나이더검사 간의 임상적 비교 조사 등의 연구를 통하여 자료를 비교 분석할 수 있었다. 또한 구강내 포도당잔류검사를 조사한 결과 등 수종의 실험연구의 경험적 연구 결과를 가지고, 한국의 여대생들과 상호관계를 비교 분석하고자 하였다. 본 연구의 조사대상은 여대생 160명을 대상으로 하였으며, 수집된 자료는 빈도, 백분율 분석으로 유의성을 검증하였다. 본 연구에서 조사된 결과는 다음과 같다. 1. 전체 조사대상자의 우식치아 수는 평균 3.23개로 조사되었고, 발거치아는 0.22개로 조사되었으며, 충전치아는 5.06개로 나타났다. 2. 전체 조사대상자의 평균 영구치 우식경험치아는 8.52개로 조사되었고, 평균 완충능력은 10.54로 나타났다. 3. 구강내 포도당잔류시간을 측정한 결과 평균 12.36 분으로 조사되었다. 4. 스나이더 검사방법 결과 조사대상자의 평균 치아우식활성 정도는 35.43 시간으로 판정기준에 의하여 중등도 활성으로 나타났다. 5. 자극성 타액분비량 및 타액점조도와 진행중인 치아우식증 보유집단과 집단간의 비교에서는 차이가 있음을 볼 수 있었다(P<0.01). 6. 비자극성 타액분비량, 자극성 타액분비량 및 구강내 포도당잔류시간 측정검사와 치아우식활성집단간에는 유의한 수준으로 나타났다(P<0.01). 7. 타액점조도에서도 치아우식활성집단간에는 유의한 수준으로 나타났다(P<0.05). 이와 같은 절과를 볼 때, 향후 연구논제에 세계보건기구(WHO)에서 기초조사로 조사되는 연령군인 12세 아동의 치아우식증과 치아우식활성과의 관계를 규명하고자 하는 노력이 있다면 치아우식증 발생요인을 구체적으로 제시할 수 있으리라 사료된다. This study was performed to investigate saliva flow rate, saliva buffer capacity, snyder test, glucose residuum test in the oral cavity in order to analyze 'saliva factor' intensively among the causing factor of dental caries. Especially through study data on causing factor of dental caries in male twenties, examination on pH changing rate in the saliva and saliva flow rate, clinical comparative study between Snyder tests, we have made a comparative analysis. Also, based on many kinds of exparimental study results from examination on glucose residuum test in the oral cavity, etc, we have intention to analyze comparatively interactive relationship of korean female college students. The subject of this study is 160 female college students, and we verified the confidence of our study data by the frequency, centesimal analysis. The results were as follows ; 1. Among the total subjects, the average of caries teeth were 3.23, extracted teeth 0.22, filling teeth 5.06. 2. Among the total subjects, the average of permanent teeth with experience of dental caries were 8.52, average buffering capacity 10.54. 3. The average minutes of glucose residual time in the oral cavity were examined 12.36 minutes. 4. On the result of Snyder examination method, the average activative degrees of dental caries were 35.43 hours rated medium level by the standard of decision. 5. There are some differencies between stimulative saliva flow, saliva adherence degree and the group of dental caries in progress. 6. There are significant results between non-stimulative saliva secretion, stimulative saliva flow, glucose remaining time test in the oral cavity and the group of dental caries in activation. 7. There are significant results between groups of dental caries in activation about saliva adherence degree. According to the results, if there is any effort in the future study theme to investigate the relationship between 12 year-old children's dental caries whose age WHO has made a basic surveying subject and activation of dental canes, we can present the causing factor of dental caries concretely.

어머니의 사회화통제유형과 아동의 자아개념

정현희,최경순 동의대학교 생활과학연구소 2000 生活科學論集 Vol.4 No.-

This study was to investigate the following research questions. (1) Are there any gender differences in the mother's socialization-patterns and child's self-concept? (2) Is there any relationship between mother's socialization-patterns and child's self-concept? (3) Is child's self-concept influenced by the mother's socialization-patterns and child's gender? The subjects of this study were 235 boys and 207 girls attending elementary schools in Busan. Lee, Kyung-Hee's questionnaires(1993) on mother's socialization patterns and Kim, Ki-Jung's questionnaires(1984) on child's academic self-concept and Kim, Hee-Kyung's questionnaires(1990) on child's physical, home, social self-concept were used. The results were as follows: 1)The mother's imperative mode for boys differed significantly from that for girls. Boys perceived mother's socialization-patterns as more imperative. And boy's physical self-concept and academic self-concept differed significantly from girl's. Boy had higher scores than girl in physical self-concept and academic self-concept. 2)There were significantly correlations between mother's position-oriented mode and boy's self-concept, between mother's poison-oriented mode and boy's self-concept. 3)The mother's poison-oriented mode was the predictor variable influencing on child's academic self-concept. And the mother's position-oriented mode and the mother's person-oriented mode were the predictor variables influencing on child's home self-concept.

SAR 영상시스템에서의 In-scene Target의 Spatial Doppler 특성을 이용한 위상오차 제거 기법

최정희,김은정 대구대학교 정보통신연구소 2003 情報通信硏究 Vol.2 No.1

SAR 영상시스템에서 목표물의 정보를 성공적으로 추출해내기 위해서는 반사된 신호를 수신할 때, Coherent detection이 필수적이다 수신시 Incoherent detection은 복소 위상오차 형태로 나타나므로 실제 목표물의 영상에 심각한 Degradation을 야기시켜 치명적인 결과를 초래하게 된다. 본 논문에서는 Incoherent detection을 야기시키는 가장 큰 원인인 Echo 데이터 측정시의 레이다와 목표물의 상대적 거리오차를 보정하기 위해 In-scene target을 이용한 위상오차 제거 기법을 제시한다. 제시된 위상오차 제거 기법은 수신된 신호를 파동 방정식으로부터 모델링하고, 각 주파수대의 전체 수신신호의 조합으로 위상오차 값을 유도한다. 또한 제시된 알고리즘은 보다 정확한 교정을 위해 반복적으로 추정된 위상오차로부터 수신신호의 오차를 제거한다. 여기서, 수신신호 측정시 위상오차를 보상하기 위해 표적 영역의 강한 In-scene target에 대한 Spatial Doppler 특성을 이용한다. 따라서 수신된 신호 중 일부만을 사용함으로써, Computation 부담과 반복 횟수를 줄일 수 있다. 본 논문에서는 컴퓨터 모의실험을 통해 발생시킨 위상오차를 포함한 수신신호에 제안된 알고리즘을 적용시켜 알고리즘의 성능을 영상으로 확인한다. The success of the target reconstruction in SAR imaging system is greatly dependent on the coherent detection Incoherent detection appears as multiplicative phase error to echoed signal, which consequently, causes fatal degradations such as fading or dislocation of target image In the paper, we proposed the phase error correction scheme using an in-scene target to compensate relative distance error between radar and target We started with modeling from wave equation for one point target and extended to overall echoed data from the target scene The proposed algonthm is also good for the correction of relatively large phase error because it can be applied repeatedly We used the spatial Doppler charactenstics of the strong in-scene target to retneve phase error in echo signal measurement We only used the partial spectral echo data to reduce computation loads and the number of iteration We venfied the performance of the proposed algonthm b) applying it to the simulated spotlght-mode SAR data

서울 雲峴宮의 立地과 空間構成

최 종 희・정 근 환 배재대학교 자연과학연구소 2012 自然科學論文集 Vol.23 No.1

본 연구는 서울 운현궁 일원의 입지와 공간구성을 분석하여 역사적, 장소적 맥락에서의 특성을 구명한 것으로, 문헌조사와 현지조사로 이루어졌으며, 주요 연구결과는 다음과 같다. 운현궁 일원의 장소성은 흥선대원군의 사저에서, 고종의 잠저로, 흥선대원군의 섭정공간으로, 이준공저로, 개인소유 공간으로, 역사교육과 시민의 휴식을 위한 장소로 변화하였으며, 장소성과 지형적 특성에 따른 공간구성은 상징공간과 생활공간으로 구분되며, 지형이 가장 낮은 남서쪽에 있는 정문으로부터 사랑영역, 안채영역, 사당영역으로 지형을 따라 배치되어, 동시대의 주택공간과 비교하여 크고 화려한 형태를 띠며, 주 건물과 행랑, 담장, 수목, 담장, 석물 등의 구성요소들이 다양하고, 구성미가 뛰어나다. 이러한 건축은 해당지역의 지형조건 등 자연적 요소와 당시의 정치체제 등의 인문적 요소와 상호 밀접하게 관련됨과 동시에 경복궁 중건 등으로 발달한 건축술의 산물이다.