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A survey of knowledge and behavior regarding skin cancer.
( Young Bin Shin ),( Jeong Won Jo ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2
Background: The recognition of prevention and early detection of skin cancer has been increased more than before. Although skin cancer is not rare, most patients are little known about general awareness of skin cancer. Objectives: In this study, we survey the awareness and knowledge of skin cancer and sun protection behavior among South-Gyeongnam province. Methods: We reviewed a written questionnaire and patients’ self-checked records including patients’ basic medical information and knowledge of skin cancer protective modalities. Results: In total 284 subjects (94.7%(284/300), 67%(190/284) females, mean age 57.4 years) completed the survey. Most people (77.5%, 220/284) knew that the sun was most dangerous for their skin but relatively large portion of them (42.7%, 94/220) had no action to protective attitude like sun screen, large hat and gloves. Conclusion: The results show that many participants had known necessity of skin cancer prevention and importance of early detection, but didn’t have had any protective action. Therefore, a more effective skin cancer education and prevention program is needed. We suggest that the measurement of effects of a multimodal educational intervention on knowledge of sun protection practices and engagement in self sun-protection behaviors also need to be check.
Benign Partial Epilepsy with Occipital Paroxysm 1례
윤석중,이영혁,김교순 건국대학교 의과학연구소 1994 건국의과학학술지 Vol.4 No.-
Benign epilepsy of childhood with occipital paroxysm is characterized by seizures which include visual symptoms followed by motor manifestations. The EEG is also characterized by repetitive occipital discharges of spikes, sharp waves or spike-wave complexes appearing only after eye closure. No occipital lesions have been found, the children are neurologically normal. Recently we experienced a case of benign epilepsy of childhood with occipital paroxysm which showed favorable response to anticonvulsant treatment. A brief review of related literatures is included in this report
工業敎育大學의 實驗實習施設 共同活用 및 運營에 關한 硏究
尹錫天,牟相榮,權五憲,千炳善,周赫鍾,李永臣,金健中,羅聲雄,洪錫雨,吳德成,盧泰天 충남대학교 공업교육연구소 1983 論文集 Vol.6 No.2(A)
The College of Engineering was specialized to have a sole function for supplying technical high school teachers in 1977 and referred to as the College of Industrial Education according to the Government's policy. The economic impact mainly due to the oil-crises caused a severe problem to this college, namely discrepancy of supply to demand scale. Accordingly the number of student enrollment was to be fluctuated from 479 in 1979 through 800 in 1979 and 900 in 1980 to 430 in 1981. And the engineering departments have been attached to this Engineering Education College since 1981. These circumstanses met singnificant inefficiency in facility operation. This program aims at providing an overall relocation of the college facilities and preparing the practical system to make the joint-operation possible taking into account circulation, academic stream, budget, maintenance, etc. However this study could not get optimal spacing but some trade-off, considering the current situation.
개 대뇌겉질에서 Platelet-Derived Growth Factor α-Receptor의 출생 후 발달에 관한 면역조직화학적 연구
윤영,안병수,김인정,양경철,박선홍,김기훈,박도영,김장만,문정석,장인엽,조하영 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.1
Background and Objectives : The localization of platelet-derived growth factor-α receptor (PDGF-α R) was commonly restricted to oligodendrocyte progenitors during late embryonic and postnatal development. However, several studies recently demonstrated that mature neurons could also synthesize PDGF-α, Materials and Methods : In the present study, to analyze the distributional pattern of PDGF-αR during postnatal development of the canine cerebral cortex, we used immunohistochemistry on sections of canine brain tissue. Results : We found that neurons of various regions of cerebral cortex exhibited the immunoreactivity to PDGF-αR as early as postnatal day 0, and slightly decreased after postnatal day 14. Whereas neuronal PDGF-αR were maintained at all ages, the oligodendroglia-like expression of PDGF-αR could not be confirmed. Conclusion : The localization of PDGF-αR in immature and mature neurons supports the several roles of PDGF during development, protection and survival of neurons.
미세유화약물송달시스템을 이용한 로바스타틴의 생체이용률 향상
윤복영,강복기,정상영,이영원,이시범,황성주,육순홍,강길선,이해방,조선행 한국약제학회 2002 Journal of Pharmaceutical Investigation Vol.32 No.4
A self-microemulsifying drug delivery system (SMEDDS) was developed to increase the dissolution rate, solubility, and ultimately bioavailability of a poorly water soluble drug, lovastatin. SMEDDS was the mixtures of oils, surfactants, and cosurfactants, which emulsify under conditions of gentle agitation, similar to those which would be encountered in the gastro-intestinal (GI) tract. Various types of self-emulsifying formulations were prepared using four types of oil (Capryol 90, Lauroglycol 90, Labrafil M 1944 CS and Labrafil M 2125), two surfactants (Cremophor EL and Tween 80), and three cosurfactants (Carbitol, PEG 400 and propylene glycol). The efficiency of emulsification was studied using a laser diffraction size analyzer to determine particle size distributions of the resultant emulsions. Optimized formulations selected for bioavailability assessment were Carpryol 90 (40%), Cremophor EL (30%) and Carbitol (30%). SMEDDS containing lovastatin (20 mg and 5 mg) were compared to a conventional lovastatin tablet (Mevacor^? , 20 mg/tab) by the oral administration as prefilled hard gelatin capsules to fasted beagle dogs for in vivo study. The area under the serum concentration-time curve from time zero to the last measured time in serum, AUC_0→24h, was significantly greater in SMEDDS, suggesting that bioavailability increase 130% and 192% by the SMEDDS, respectively. The self-emulsifying formulations of lovastatin afforded the improvement in absolute oral bioavailability relative to previous data of lovastatin tablet formulation. These data indicate the utility of dispersed self-emulsifying formulations for the oral delivery of lovastatin and potentially other poorly absorbed drugs.
[P509] Lichen planus pigmentosus presenting with flexural area
( Young Bin Shin ),( Jeong Won Jo ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1
Lichen planus pigmentosus (LPP) is an uncommon variant of lichen planus that tends to occur in middle-aged individuals with darker pigmented skin. Clinical findings include hyperpigmented, brown to gray-brown macules and patches on sun-exposed areas and, in the rare inversus variant, on the flexural areas and intertriginous zones. The pattern of pigmentation is generally diffuse, although follicular, reticular, and unilateral linear variants have been described. We recently encountered a rare case of LPP developed in flexural area, not in sun-exposed area. A 58-year-old male patient presented with brown macules on the inguinal area for 6 months. One or two dark brown macules first appeared and spread gradually. A physical examination showed multiple, ill-defined, dark brown macules on inguinal area. The dermoscopic finding showed mottled pattern and elevated margin. The incisional biopsy was performed and a diagnosis of LPP was made. The fact that LPP can develop in non-sun-exposed areas as well as sun-exposed ones requires a new hypothesis for the pathogenesis of LPP.
Sun-young Park,Youngjae Lee,Jinyoung Song,Seok-ho Jeon,Ji-yoon Jeong,강병택,강지훈,장진화,장동우 한국임상수의학회 2016 한국임상수의학회지 Vol.33 No.3
Signalment: An 8-month-old female Alaskan malamute was presented for progressive cluster seizure disorder. Results: There were no abnormalities on neurological examination, survey radiographs, or blood analysis. Magnetic resonance (MR) imaging and computed tomography revealed extension of the olfactory bulb and frontal lobe into the nasal cavity. They also confirmed abnormal anatomy of the nasal turbinates within the rostral part of the nasal cavity and the absence of a cribriform plate. On T2-weighted and fluid-attenuated inversion recovery images, the herniated brain showed heterogeneous and hyperintense signals consistent with intraparenchymal edema. Transverse MR images showed brain herniation into the right frontal cavity and an asymmetrical lateral ventricle because of a left midline shift. On contrast-enhanced MR images, the protruding brain parenchyma was mildly enhanced. Ethmoidal encephalocele was suspected as the final diagnosis. Despite symptomatic treatment, the dog continued to exhibit seizures and was euthanized. Clinical relevance: Ethmoidal encephalocele is a rare disease in dogs. However, it could be considered as a cause of seizure in young dogs.