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유기용매 추출법과 산가수분해에 의한 포플라의 전처리 및 효소당화액을 이용한 생물고분자의 생산에 관한 연구
김균성,박정극 동국대학교 산업기술대학원 1993 산업기술논문집 Vol.1 No.-
In this study the lignocellulosic biomass, Italy poplar, was pretreated by the chemical pretreatment method, i.e., organic solvent (Phenol/H_2O) extraction. Using Phenol/H_2O solvent system. Wood yield, % delignification and % sacchari-fication(72hours) of poplar after pretreatment at 190℃, 60 min. which was found out as the optimum pretreatment condition, were 46,3%, 96.1% and 83.35% (43.87 g/L) respectively. The possibility of reusing the spent organic solvent and recovery of hemicellulose fraction were also studied. By recycling spent black organic solvent in this process, we obtained an approximately identical results. The percent saccharification of 79.9% (43.6 g/L) was obtained from the recycled process and the degree of delignification was more than 99%. The delignification reactions using Phenol/H_2O solvent system showed two distinct mechanism of pseudo first order reactions (fast and slow), and the activation energy of the fast reaction was 38.4Kcal/gmol. For the recovery of hemicellulose fraction, poplar wood was pretreated using acid as a catalyst at high temperature and low concentration;180℃,0.05%∼0.15 vol% H_2SO_4(HTLC), and also at low temperature and high concentration;120℃,1∼4 vol% H_2SO_4(LTHC). 58% of hemicellulose was recovered whin the Italy poplar was pretreated at 180℃ with 0.1 vol% H_2SO_4 for 10 minutes (HTLC), and 74.4% recovery of hemicellulose fraction was obtained when it was pretreated at 120℃ with 4 vol% H_2SO_4 (LTHC) for 20 minutes, which is considered as an optimum condition for hemicellulose recovery. And after these acid hydrolysis followed by solvent extraction at 190℃, 60 min, the lower amount of sugar was obtained compared to one-step solvent extraction which was studied. As an application of saccharified broth, the culture of Zoogloea remigera 115 which produces biopolymer adsorbing heavy metals (Cu, Fe, Zn, Co etc) was conducted. When saccharified broth was used as a carbon source, the lag phase of the fermantation was longer than that of synthetic glucose media. After 60 hours of fermentation, the maximum cell density of 1.5 g/L was obtained. Final biopolymer concentration was 10.05 g/L after 200 hours of fermentation. Above experimental results showed the possibility of using saccharified broth as a carbon sourse for fermentation media.
서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1994)
김재홍,안진균,정성재,김영태,김중환,김시영,이석종,이홍렬,서호석,김경훈,권혁진,정우권,고우석,이용석,안필수,오준규,오용섭 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1
Background : In recent years gonorrhoea has been panendemic and remains one of the most common Sexually Transmitted Diseases in the world, especially in developing countries. Objective & Method : For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria Gonorrhoeae(PPNG), Ive have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1994, 168 strains of N. gonorrhoeae were isolated, among which 109 (64,9% ) were PPNG. Conclustion : Our results suggests that the prevalence of PPNG in Seoul is still increasing.
The ROM Design with Half Grouping Compression Method for Chip Area and Power Consumption Reduction
JUNG, Ki-Sang,KIM, Kang-Jik,KIM, Young-Eun,CHUNG, Jin-Gyun,PYUN, Ki-Hyun,LEE, Jong-Yeol,JEONG, Hang-Geun,CHO, Seong-Ik The Institute of Electronics, Information and Comm 2009 IEICE transactions on electronics Vol.92 No.3
<P>In memory design, the issue is smaller size and low power. Most power used in the ROM is consumed in line capacitance such as address lines, word lines, bit lines, and decoder. This paper presents ROM design of a novel HG (Half Grouping) compression method so as to reduce the parasitic capacitance of bit lines and the area of the row decoder for power consumption and chip area reduction. ROM design result of 512 point FFT block shows that the proposed method reduces 40.6% area, 42.12% power, and 37.82% transistor number respectively in comparison with the conventional method. The designed ROM with proposed method is implemented in a 0.35µm CMOS process. It consumes 5.8mW at 100MHz with a single 3.3V power supply.</P>
Jung Gyoohwan,Kim Jung Kwon,Jeon Seong Soo,Chung Jae Hoon,Kwak Cheol,Jeong Chang Wook,Ahn Hanjong,Joung Jae Young,Kwon Tae Gyun,Park Sung Woo,Byun Seok-Soo 대한남성과학회 2023 The World Journal of Men's Health Vol.41 No.1
Purpose: To establish a prospective registry for the active surveillance (AS) of prostate cancer (PC) using the Korean Urologi-cal Oncology Society (KUOS) database and to present interim analysis. Materials and Methods: The KUOS registry of AS for PC (KUOS-AS-PC) was organized in May 2019 and comprises multiple institutions nationwide. The eligibility criteria were as follows: patients with (1) pathologically proven PC; (2) pre-biopsy prostate-specific antigen (PSA) ≤20 ng/mL; (3) International Society of Urological Pathology (ISUP) grade 1 or 2 (no cribriform pattern 4); (4) clinical T stage ≤T2c; (5) positive core ratio ≤50%; and (6) maximal cancer involvement in the core ≤50%. Detailed longitudinal clinical information, including multi-parametric magnetic resonance imaging and disease-specific out-comes, was recorded. Results: From May 2019 to June 2021, 296 patients were enrolled, and 284 were analyzed. The mean±standard deviation (SD) age at enrollment was 68.7±8.2 years. The median follow-up period was 11.2 months (5.9–16.8 mo). Majority of pa-tients had pre-biopsy PSA ≤10 ng/mL (91.2%), PSA density <0.2 ng/mL2 (79.7%), ISUP grade group 1 (94.4%), single positive core (65.7%), maximal cancer involvement in the core ≤20% (78.1%), and clinical T stage of T1c or lower (72.9%). Fifty-two (18.3%) discontinued AS for various reasons. Interventions included radical prostatectomy (80.8%), transurethral prostatec-tomy (5.8%), primary androgen deprivation therapy (5.8%), radiation (5.8%), and focal therapy (1.9%). The mean±SD time to intervention was 8.9±5.2 months. The reasons for discontinuation included pathologic reclassification (59.6%), patient pref-erence (25.0%), and radiologic reclassification (9.6%). Two (4.8%) patients with pathologic Gleason score upgraded to ISUP grade group 4, no biochemical recurrence. Conclusions: The KUOS established a successful prospective database of PC patients undergoing AS in Korea, named the KUOS-AS-PC registry.