S-344 : The Role of Skeletal Muscle Mass in Development of Metabolic Syndrome

( Byung Sam Park ),( Jun Sung Moon ),( Ji Sung Yoon ),( Kyu Chang Won ),( Hyoung Woo Lee ) 대한내과학회 2013 대한내과학회 추계학술대회 Vol.2013 No.1

Introduction: It has been well known that abdominal adiposity is related with insulin resistance and greater risk of metabolic disorder. Skeletal muscle plays central role in insulin mediated glucose disposal of whole body, but we only know a little about the association between skeletal muscle mass and MetS (MetS). The aim of this study is to clarify the clinical role of skeletal muscle mass in developing MetS through using skeletal muscle parameters by body impedance analysis (BIA). Methods: 1,042 healthy adults aged from 20 to 75 years who visited Yeungnam university health promotion center from Jun. 2008 to Jun. 2010 were enrolled. 204 subjects who had prior MetS or chronic disease that can affect to skeletal muscle mass were excluded. After 24 months from baseline, the metabolic parameters were assessed and the development of MetS was diagnosed using modified NCEP-ATP III criteria. From the BIA (Inbody 720), we obtained skeletal muscle mass (SMM, Kg), body fat mass (BFM, Kg), and visceral fat area (VFA, cm2). Then, we had defined as follows; percent of skeletal muscle mass (SMM%, %): SMM (kg)/weight (Kg), skeletal muscle index (SMI, Kg/m2): SMM (Kg)/height (m)2, skeletal muscle to body fat ratio (MFR): SMM (kg)/BFM (Kg) and skeletal muscle to visceral fat ratio (SVR, Kg/cm2): SMM (Kg)/VFA (cm2) Results: Mean follow up periods were 28.7±5.4 months. Among total 838 subjects (46.9±9.9 years, M:F=477:361), 88 (10.5%) were newly diagnosed MetS. 5th quintile of the SMM%, MFR and SVR was associated with decreased risk of development of MetS after adjusting for confounding factors. Conclusion: Decreased skeletal muscle mass may play critical role in development of the MetS and not absolute amount of skeletal muscle mass but relative ratio to body composition may be more important.

CT사진을 이용한 한국인의 C형 치근관의 분포에 대한 연구

전록원,허경회,이원진,허민석,이삼선,최순철 대한구강악안면방사선학회 2009 Imaging Science in Dentistry Vol.39 No.2

Purpose : To investigate the incidence and prevalence of C-shaped root canal using computed tomographic images of head and neck in Korean population. Materials and Methods : Regardless of each examination purpose, randomly selected 268 examples which have serial axial computed tomographic images with 8 normal molars in maxilla and mandible were selected and investigated. Defined C-shaped root canal and we could get 82 proper image examples in view of this definition. These were detected and investigated of incidence and prevalence of C-shaped root canal. Results : C-shaped root canals were found in 82 examples among 268 (30.6%) and 147 teeth. They were only found on molar area, and the highest incidence was 37.41% of left mandibular second molars, and the lowest was 2.04%of right maxillary second molars. On prevalence of tooth position, mandibular second molar was the highest, 65% of C-shaped root canal teeth and maxillary second molar was 6% the lowest. Conclusion : 31% of randomly selected CT images no considering check-up reason have C-shaped root canals. The C-shaped root canals of mandibular second molar are found most frequently and they are also detectable on maxilla. On Korean population, C-shaped root canals are one of conditions that have to concern with dental treatment for it appears at a high prevalence relatively.

Interleukin-2가 Mouse 골수에 미치는 영향

박준영,이군자,정호삼,이규식 대한해부학회 1990 Anatomy & Cell Biology Vol.23 No.3

골수에서 혈구형성과정은 interleukin-3, interleukin-4 및 임파구 분비물질 등의 액소성 인자와 대식세포 및 임파구에 의하여 조절되며, 흉선 및 비장에서 형성되는 임파구의 조절은 interleukin-2가 관여한다. Interleukin-2 는 T 임파구에서 분비되는 T 임파구 성장인자로서 세포독성임파구의 증식을 유도하고 임파구의 활성을 증가시켜 여러 육종 및 암종에 탁월한 효과를 나타내는 종양치료제이나 interleukin-2를 암환자에 투여하면 가역적 호산구증가증, 말초혈액임파구의 변동 등 혈액학적 독성이 야기된다. 이에 저자는 mouse에 interleukin-2를 투여하면 흉골 골수에서 임파구 발생이 변동될 것으로 사료되어 mouse에 interleukin-2를 투여한 후 나타나는 흉골임파구의 변동을 관찰하였다. 실험동물로는 체중 15gm 내외의 웅성 mouse를 사용하였으며 체중 ㎏당 200만 단위의 interleukin-2, 0.2ml를 복강내에 주사하고 3시간, 6시간, 12시간, 24시간 및 48시간 경과 후에 각각 희생시켜 흉골을 적출하고 Zenker 용액에 고정한 후 Hematoxylin-eosin-azure II 염색을 시행하여 다음과 같은 결과를 얻었다. 1. Interleukin-2 투여 3시간 경과군의 mouse 흉골골수에서는 소형임파구가 약간 증가하였으며 6시간 경과군 및 12시간 경과군에서는 소형임파구가 현저히 증가하였다. 2. Interleukin-2 투여 24시간 경과군 및 48시간 경과군의 mouse 흉골골수에서는 미분화 혈구세포들이 다수 관찰되었다. 이상의 결과를 종합하면 interleukin-2는 흉골의 임파구 형성에 관여하는 것으로 사료된다. It is known that hemopoiesis is regulated by lymphocytes, macrophages and T lymphocyte-derived lymphokines, and lymphopoiesis in thymus is controlled by the interleukin-2. Interleukin-2 is a T-cell growth factor produced by antigen or mitogen activated T lymphocyte, and mediates antitumor effect by stimulating the differentiation of precurssor T cells into lymphokine activated killer cells. Although, interleukin-2 shows therapeutic effects on various sarcoma and carcinoma, it induces many hematologic toxicities, reversible eosinophilia and marked changes in peripheral lymphoid cells. Therefore the author undertook the present study to pursue the effect of interleukin-2 on the lymphocytes in the sternal marrow. Albino mice, DDY strain, weighing 15 gm were used as experimental animals. Experimental animals were killed at 3, 6, 12, 24 and 48 hours after administration of 2,000,000 unit/㎏ inter leukin-2. The specimens obtained from the sternum were stained with Hematoxylin-eosin-Azure II for histological observation. The results were as follows. 1. The number of small lymphocytes were increased slightly in the sternal marrow at 3 hours after interleukin-2 injection and considerably increased in the 6 hours and 12 hours group. 2. Undifferentiated hemopoietic cells were observed numerously at the 24 and 48 hours after interleukin-2 injection. Consequently, it is suggested that interleukin-2 would influence the lymphopoiesis in the mouse sternal marrow.

2인과 3인의 기본 심페소생술 비교

정준영,이창현,김현정,도호석,이삼범,도병수 大韓應急醫學會 1997 대한응급의학회지 Vol.8 No.1

Study objectives: To compare the quality of CPR provided by medical students and pre-EMTs perfoming three-rescuer CPR with that achieved by same students trained to provide standard two-rescuer CPR and to find the most effective method of resuscitation and to educate this methods to students. Material and methods: From July 1 to September 30, 1996, we had trained 60 groups consisted of the medical students, students of EMS technology and pre-EMT. Each group practiced two-rescuer CPR and three-rescuer CPR for 120 minutes with Resusci? Anne and perfomed CPR for at least 3 minutes without feedback. To eliminate any visual cues of perfomance the mannequin's recorder was hidden. Each actions were recorded by Resusci? skillmeter and Laerdal printer. To compare the quality of two-rescuer CPR and three-rescuer CPR, we analyzed the data by SPSS with paired t-test. Results: Three-rescuer teams delivered a mean minute ventilation and a mean minute cardiac compression substantially greater than that produced by two-rescuer teams(11.30±1.85 vs 9.09±2.22, p<0.001; 99.22±12.42 vs 95.12±15.75, p<0.001). Three-rescuer teams produce the more correct actions in chest compression and ventilation(93.84±7.56% vs 83.49±16.94%, 90.90±9.33% vs 77.00±17.06%). Conclusion: Three-rescuers can produce better CPR than two rescuers when a bag-valve-mask devices is used and the technique is easily learned and readily retrained, so we think that repeated education and training of this CPR methods to students is needed.

급성흉통으로 내원한 환자에서 심근경색증을 조기 발견하기 위한 TROP-T?Rapid Assay의 유용성

정준영,이창현,김현정,도호석,이삼범,도병수 대한응급의학회 1996 대한응급의학회지 Vol.7 No.2

Study Objectives : In the past, measurement of cardiac enzymes(i.e. CK and/or CK-MB, GOT, LDH)and myoglobin, cardiac specific serum troponin-T were widely used for the diagnosis of acute myocardial infarction, but it need a long time and have low specificity. Thus new diagnostic modality, TROP-T?? Rapid Assay, is very easy and rapid qualitative methods, is needed for the early detection of acute myocardial infarction. Methods : Total CK, GOT, LDH, myoglobin and serum troponin-T activities were measured in patients presenting with acute chest pain at the emergency department and at the same time TROP-T? Rapid Assay was done. Final diagnosis and diagnostic usefulness was evaluated. Results : Overall diagnotic sensitivity and specificity of initial results were as follows; TROP-T? Rapid Assay, 77.3, 100.0; myoglobin, 63.6, 70.4; CK, 95.5, 96.3; GOT, 86.4, 96.3; LDH, 90.9, 92.6; serum troponin-T, 86.4, 96.3, respectively. Conclusion : The TROP-T?? Rapid Assay is simple method and has a short time and nearly same sensitivity and specificity compared to other cardiac enzymes. Thus this is considered useful method in the early detection of acute myocardial infarction at emergency department.

외상성 간손상과 비장손상시 CT분류의 의의

정준영,이창현,김현정,도호석,이삼범,도병수 大韓應急醫學會 1997 대한응급의학회지 Vol.8 No.1

The Organ Injury Scaling Committee of the American Association for the Surgery of Trauma recently published a consensus classification of hepatic and splenic injuries. The hepatic and splenic injury scales, based on parenchymal laceration and intrahepatic hematoma, include grade 1 to 6 and grade 1 to 5 respectively, representing the least to most severe injury. Forty-eight patients with hepatic and splenic injury were evaluate by abdominal CT from January 1995 to May 1996 and we compared abdominal CT grading with operative grading. Four CT grades did not correlate with operative finding. CT grading showed a sensitivity of 80%, specificity 80% in regard to operative grading. We conclude that 1) CT is an accurate technique to determine the extent of hepatic and splenic injury. 2) CT grading of hepatic and splenic trauma has a high correlation with operative grading.

水稻種子의 Paclobutrazol浸漬處理가 苗素質에 미치는 影響

趙東三,李尙榮,金俊泰 충북대학교 농업과학기술연구소 1986 農業科學硏究 Vol.4 No.-

This experiment was carried out to evalute the effects of paclobutrazol (PP-333) on the characters of mechanical transplanting rice seedlings at the Chungbuk National University in 1986. The results obtained were summarized as follows. 1.Paclobutrazol appeared to be very effective to reduce plant height of seedlings. Highly significant difference in plant height of seedlings among paclobutraszol concentration was noted for all varieties tested. 2.Paclobutrazol at higher than 10 ppm increased the number of leaves of 40-day-seedlings for all varieties. It appeared that number of leaves was increased as paclobutrazol concentration was increased. 3.Although dry weight of seedlings was reduced, dry weight/plant height, which indicates the degree of seedlings substantiality, tended to be increased as paclobutrazol concentration was increased.

朝鮮朝 書院敎育의 實際와 社會的 役割에 關한 硏究

張德三,李鐘祿,辛堯永,金俊基,李相基 圓光大學校 敎育問題硏究所 1989 敎育硏究 Vol.- No.8

The brief contents about the background of the appearance of Seo-won in Yi-Dynasty, the actual state of its education and its social role are as follows : 1. Our nation’s Seo-won was not settled as a Confucian educational institute until Sun Confucianism (性理學) was introduced in the middle of Yi-Dynasty. 2. The ultimate purpose of the Seo-won education was to establish the permanent aim of the following saints (法聖賢) and to cultivate sages by laying emphases on the ethical and moral education and the state examination education. 3. So-hak (小學) and Ka-lye (家禮) were introductory courses and Sa-se (四書) and Oh-kyeong (五經) were fundamental ones in the contents of education. 4. It took the educational method of Joo Ja (朱子) in Song-Dynasty and emphasized practical moral education by autere training syatem. 5. They administered it by the income of real estate which they secured, while they expanded its paddy fields with surplus income. 6. The educational system and equipment of Seo-won was similar to that of China which had a director and Yoo Sa (有司) system although there was some difference according to the class of Seo-won. 7. Seo-won did its duty as the distribution of information, the promotion of Confucianism, the enlightment of their countries, the inheritance of their traditional culture, the foundation of science and the publication or custody of publications.

사과 種自의 發芽와 水分含量과의 關系

鄭三澤,金益弘,김유신,李啓準,申聖鍊 경북대학교 1988 새마을 硏究論叢 Vol.9 No.-

폐경기 여성의 운동형태가 골밀도에 미치는 영향

김은경,이계영,이삼준,심영제 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

The relationship of bone mineral density and type of physical exercise was studied in 36 Postmenoposal Women(age 48-57). The exercise group consisted of Weight training([ =9), Aerobic dance(N=8), Swimming(N=9) and the control group consisted of 10 women. Bone mineral density was measured Lumber(L2-L4), Femur neck, Ward's triangle bone density. The results statstically analyzed on these data were summarized as follows: first, Lumber (L2-L4) bone density, Femoral neck bone density, Ward's triangle bone density in Weight training group was significantly higher than in Swimming group and Control group. Secondly, Lumber(L2-L4) bone density, Femoral neck bone density, Ward's triangle bone density in Aerobic dance group was significantly higher than in Swimming group and control group. Thirdly, No significant difference were round for Lumber(L2-L4) bone density, Femoral neck bone density in Weight training group and Aerobic dance group.