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      • KCI등재

        Swimming during pregnancy increases the expression c-Fos and c-Jun in the hippocampus of rat offspring

        심영제,김지연,김창주 한국운동영양학회 2009 Physical Activity and Nutrition (Phys Act Nutr) Vol.13 No.1

        The expression of c-Fos and c-Jun represents neuronal activity and plays a crucial role in the shaping of the development of brain. During the late pregnancy, exercise is known to influence neuronal activity of offspring. In the present study, the effect of swimming during pregnancy on the expression of c-Fos and c-Jun in the CA1, CA2, CA3 regions, and the dentate gyrus of the hippocampus of rat offspring was investigated using immunohistochemistry. Pregnant rats in the swimming group were forced to swim for 10 min once a day from 15 days after pregnancy until delivery. The expression of c-Fos and c-Jun in the CA1, CA2, CA3 regions, and the dentate gyrus of the hippocampus of pups was significantly increased by maternal swimming during late pregnant period. The present results show that prenatal swimming may enhance the neuronal activity of pups and affect the neonatal brain development.

      • KCI등재

        Treadmill exercise alleviates impairment of spatial learning ability through enhancing cell proliferation in the streptozotocin-induced Alzheimer’s disease rats

        심영제 한국운동재활학회 2014 JER Vol.10 No.2

        Alzheimer’s disease is the most common cause of dementia. This dis-ease is a progressive and irreversible brain disorder accompanied with severe learning and memory impairment. Exercise increases cognitive ability, attenuates motor deficits, increases new neuron formation, and ameliorates neurological impairments in several neurodegenerative dis-eases. This study investigated the effects of treadmill exercise on spatial learning ability in relation with cell proliferation in the hippocampus. The rat model of Alzheimer’s disease was induced by intracerebroventricular (ICV) injection of streptozotocin (STZ) using a stereotaxic instrument. The rats in the exercise groups were forced to run on a treadmill for once 30 min daily for 28 consecutive days starting at 3 days after the ICV injection of STZ. Radial 8-arm maze test was conducted for the spatial learning ability. New neuron formation in the hippocampus was detect-ed by 5-bromo-2’-deoxyuridine (BrdU) immunohistochemistry. Brain-de-rived neurotrophic factor (BDNF) and tyrosine kinase B (TrkB) expres-sions were examined by western blot analysis. The present results show that ICV injection of STZ impaired spatial learning ability. Decreased cell proliferation with decrement of BDNF and TrkB expressions in the hip-pocampus were observed in the STZ-induced Alzheimer’s disease rats. However, treadmill exercise alleviated deficits of spatial learning ability. Treadmill exercise enhanced cell proliferation and increased BDNF and TrkB expressions in the rats with ICV injection of STZ. The present study suggests that treadmill exercise can be a useful strategy for treating memory impairment induced by several neurodegenerative diseases.

      • 심혈관질환자를 위한 유산소 심장재활운동

        심영제(Sim Young Je),김상호(Kim Sang Ho),허안식(Her An Sik),이중철(Lee Jung Chul) 한국유산소운동과학학회 2016 한국유산소운동과학회지 Vol.14 No.1

        A majority of studies have demonstrated that regular physical activity and exercise training decrease cardiac mortality and all cause mortality, the recurrence of nonfatal myocardial infarction, and the necessity of revascularization procedures. aerobic exercise may be strongly dependent on clinical presentation and was more frequent in patients with CAD Cardiopulmonary cardiac rehabilitation is a comprehensive program of exercise and education that helps patients with heart disease return to their former daily lives, and furthermore, maintain their physical, emotional and socially healthy and productive lives. Cardiac rehabilitation programs include aerobic exercise therapy, behavior modification, lifestyle and stress management, adjustment of other risk factors. The goal is to reduce the incidence of heart disease and delay or prevent disease progression, ultimately increasing the quality of life of the patient and lowering the mortality rate. It has also been shown to improve exercise capacity, psychological functioning, and risk factor management. Patients with cardiovascular disease can safely exercise observing a few instructions. For this, exercise tests need to be done to identify the risk of heart attack resulting from exercise, and high-risk patients need to be under a doctor’s supervision while performing exercise training for a certain time. In contrast, low-risk patients can receive exercise prescriptions with basic instructions for exercise training to exercise in their homes. It i s important that e xercise b ecomes a regular part o f patients p astime a ctivity in o rder t o continuously see the effects of cardio-protection from exercise.

      • KCI우수등재

        중학교 테니스선수의 성별, 경력수준에 따른 스포츠상해 연구

        심영제(SimYoung-je),이중철(LeeJung-chul) 한국체육학회 2017 한국체육학회지 Vol.56 No.1

        본 연구의 목적은 유소년 선수들의 테니스와 관련된 운동상해의 형태와 발생원인 등을 파악하여 선수코칭, 부상방지 및 재활치료를 위한 기초적인 자료를 제공하는데 그 목적이 있다. 피험자는 중학교 테니스 선수들로 남ㆍ여 100명씩 총 200명을 대상으로 하였다. 본 연구의 검사 도구는 테니스 스포츠상해 예방을 측정하기 위해 설문지를 이용하여 상해 부위, 상해 형태, 상해의 원인으로 분류하였다. 상해의 원인분석을 통해 도출한 주요 결과는 다음과 같다. 성별에 따른 상해부위는 남녀모두 상지에 비해 하지의 상해발생 비율이 높게 나타났다. 상해 형태는 남녀모두 좌상과 염좌가 가장 높게 나타났으며 염좌와 요통의 경우 여자가 남자보다 통계적으로 유의하게 높게 나타났다. 경력별 상해형태는 경력이 낮을수록 골절의 위험성이 높은 것으로 나타났으며 좌상의 경우는 경력이 많을수록 상해가 높게 나타났다. 찰과상 또한 경력에 따른 차이가 있는 것으로 나타났다. 상해의 발생원인은 남녀모두 본인 부주의가 가장 높게 나타났다. 결론적으로 유소년 테니스 선수들의 상해의 예방을 위해서 충분한 준비운동과 정리운동이 실시되어야 하고 운동학적 사슬을 최적화 시킬 수 있도록 하지 근육강화, 체간부 안정화 운동과 스트레칭이 매우 중요하다고 하겠다. 아울러, 유소년 선수들의 경쟁불안은 시합의 외적인 부분에서도 발생될 수 있기 때문에 세심한 주의를 기울여야 하며 상해 위험이 높은 선수들에게 다양한 예방 프로그램을 제공하는 것이 매우 중요하다고 생각된다. The purpose of this study was to provide basic data for player coaching, injury prevention and rehabilitation in the future by analyzing the types, locations and causes of various sports injuries related to tennis among youth athletes by gender and career. The subjects were 200 middle school tennis players, 100 male and female. In order to measure the prevention of tennis sports injuries, this study used questionnaires to classify locations, types and causes of injury. The main results from the cause analysis of injury were as follows: The incidence of injuries of the lower extremities was higher in the injured area according to gender than in the upper extremity. The type of injury was the highest in both men and women with strain and sprain, especially sprain and back pain were significantly higher in women than in men. As for the type of injury by career, the lower the career, the higher the risk of fracture. In case of strains, the higher the career, the higher the injury and there was also a difference in abrasion according to career. Carelessness was the highest cause of injury for both men and women. In conclusion, enough warm up and cool down should be performed to prevent injuries of youth tennis players, and muscle strengthening, stabilization of body part and stretching are very important to optimize the kinetic chain. In addition, competition anxiety among youth players can occur in the outward part of the game, so it is very important to pay attention and provide various preventive programs to players who are at high risk of injury.

      • KCI등재

        대사증후군에 따른 혈관 내피세포 기능 부전과 운동

        황문현,심영제 대한비만학회 2015 The Korean journal of obesity Vol.24 No.3

        심혈관 질환 위험 인자의 결집체인 대사증후군은 전 세계적으로 전염병처럼 만연하고 있으며, 우리나라를 포함한 서구 발전된 국가들의 경우 성인 인구의 약 30% 정도가 대사증후군으로 분류되고 있다. 혈관 내피세포 기능은 동맥 경화성 심장 질환을 예측하는 예후인자이며, 타당도와 신뢰도가 기 입증된 초음파를 이용한 혈류매개 혈관확장 반응을 통해 측정 및 평가가 가능하다. 대사증후군에 따른 혈관 내피세포 기능 부전에 관련된 생리학적 기전은 아직까지 명확히 밝혀지지 않았으나, 동물 연구를 통해 인슐린 저항성 증가와 고혈당으로 인한 혈관 내피세포 내 산화 스트레스 증가에 따른 일산화질소 생이용성 감소가 주된 원인으로 추측되고 있다. 국외 문헌을 바탕으로 장기간의 유산소 운동은 대사증후군 환자의 혈관 내피세포 기능에 긍정적인 영향을 미치는 것으로 나타나고 있으나 과학적 증거의 양이 미흡하고 관련 생리학적 기전은 아직까지 명확하게 밝혀지지 않고 있다. 따라서 앞으로 다양한 운동 종류와 강도를 적용하여 대사증후군에 따른 혈관 내피세포 기능 부전을 개선시키는 데 가장 효과적인 운동 방법을 찾아내고 관련 생리학적 기전을 밝히는 것이 요구되며, 이는 비만, 당뇨, 대사증후군 환자의 심혈관 건강을 개선시키기 위한 운동처방 및 운동치료 프로그램의 개발 및 발전을 유도하여 대사증후군 환자의 심혈관 질환 위험을 감소시키는 데 기여할 것이다. Metabolic syndrome, a constellation of cardiovascular disease risk factors, is a global pandemic. Over 30% of the adult population in both South Korea and the United States are currently classified as having metabolic syndrome. Vascular endothelial function is a precursor of future atherosclerotic cardiovascular disease. Conduit artery flow-mediated dilation using ultrasonography is considered the non-invasive, gold standard for assessing nitric oxide-mediated vascular endothelial function. Patients with metabolic syndrome commonly exhibit increased insulin resistance and hyperglycemia, which are thought to impair vascular endothelial function by increasing oxidative stress and reducing nitric oxide bioavailability in the vascular endothelium and in smooth muscle cells. Previous findings have indicated that long-term aerobic exercise has a positive effect on impaired vascular endothelial function in metabolic syndrome patients, but the underlying mechanisms have not been fully elucidated. Therefore, further studies are needed that will apply different exercise modalities and intensities with the goal of improving vascular endothelial function in patients with metabolic syndrome, as well as investigation of the associated mechanisms. Ultimately, well-designed future studies will help to establish and develop exercise prescription and/or exercise therapy programs that can reduce cardiovascular disease risk and improve cardiovascular health in metabolic syndrome patients.

      • KCI등재
      • KCI등재

        운동 참여 전 흡연이 심폐기능 및 피로에 미치는 영향

        최희남,심영제,유재현,정재훈,주미현 한국사회체육학회 2008 한국사회체육학회지 Vol.0 No.32

        Smoking is one of the ,most important risk factors for future cardiovascular morbidity and a major cause of cardiovascular disease mortality. More than one in 10 cardiovascular deaths worldwide is caused by smoking. The purpose of this study was to examine the responses of cardiorespiratory capacities and lactate during the exercise according to cigarette smoking and nonsmoking on smokers. The statistical analysis indicated that non-smoking situation group had significantly higher at Maximal oxygen consumption, ventilatory threshold, exercise duration time compare to smoking situation group. The results suggest that the negative effects of acute smoking on pulmonary function, aerobic power and peripheral blood flow.

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