忠北 『生命의 숲』 造成成果와 環境性 提高를 爲한 "새천년손자숲"造成方案

柳乙烈,金洪殷,朴在仁 충북대학교 농업과학기술연구소 2000 農業科學硏究 Vol.17 No.-

Since 1996 the government of Chungbuk province has established and managed "Forest for Lif" to enhance the environmental effects of forest on human life. In the year of 1998, "the National Campaign for Establishing Forests for Life" in initiated nationally as a civil movement. In this study, the achievements of "Forests for Life" in Chungbuk province and "Forests for New Millenium Grandson", a new movement driven by the provincial government, were reviewed in terms of environmental science, public economy, forest policy and planning to maximize their environmental effects. The followings are suggested. Four ways of financial supports(fund-raising, donation of seedlings, provincial bond, and public fund) are suggested for running the movement. Among these methods, fund-raising is considered the most proper one. The establishment of model "Forests for New Millenium Grandson" is proposed in public land rather than private land in every city and county in Chungbuk area, after consideration of environmental factors such as soil and wind direction. Three type of "Forests for New Millenium Grandson", forested park, ecology Park, and urban park, are recommended to develop, and each park should have its optimum size due to the own environmental characteristics. Tree species recommended by Chungbuk Forestry Authorities and showing low susceptibility to pollutants are recommended to be planted for "Forests for New Millenium Grandson" movement. The following suggestions are recommended for better "Forests for New Millenium Grandson". 1) Environmental education should be spread to the general public for effective volunteering participation in tree planting. 2) As for enterprises, total control system combining afforestation performance and carbon dioxide output to induce to participate the movements. 3) In the case of selecting "the model company for environmental quality control", the Ministry of Environment authorities has suggested to include afforestation effort as a selecting criteria, Otherwise, the governor of the province should have full authority to select the winning company for environmental quality control.

맹장을 제거한 성계숫닭에 의한 國內産 肉鷄 내장분말의 有效 아미노산 利用率

李乙衍,金炯浩,車章玉,朴弘錫 全北大學校 1994 論文集 Vol.38 No.-

This study was designed to compare true digestible amino acid values for broiler offal meal with available amino acid values. Broiler offal meal was each force-fed to 6 intact and 6 caecectomised adult cockerels For each test, Cockerels were starved of food for 24 h, fed, and then excreta collected for 48 h. Crude protein, ether extract and ash of broiler offal meal were 50.5%, 16.7%, and 11.7%, respectively. True digestibilities of all seventeen measured amino acids were lower for caecectomised than intact cockerels, with the average difference being approximately 0. 10. True available amino acid of broiler offa meal was higher values for cystine and aspartic acid in intact than in caecetomised cockerels. Generally leucine, isoleucine and glutamic-acid were among the most available amino acids, while cystine, aspartic acid and threonine were among the least available amino acids in broiler offal meal for caecectomised cockerels.

강원도산 참당귀와 일본산 일당귀의 생리 활성 성분 탐색

함문선,김성수,홍종수,이진하,정을권,박영식,이현용 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.5

참당귀와 일당귀를 에탄올로 추출하였고 이들 추출물들을 디에틸 에테르층과 물층으로 분획하였다. 두 개의 분획물들은 Ames mutagenicity test에서 MNNG(0.5 ㎍/plate)에 대한 강한 항돌연변이 효과를 나타내었다. 디에틸 에테르 분획물들은 MNNG의 돌연변이원성을 78%에서 80%까지 억제시켜 가장 강한 돌연변이 유발 억제효과를 보여주었다. 각각의 에탄올 추출물(1㎍/㎕)들은 사람의 다양한 암세포들의 성장을 억제시켰다. 특히, 디에틸 에테르 분획물들은 간암 세포의 생육을 90%에서 95%까지 억제시켜 가장 강한 항암효과를 보여주었다. 그러나 수층 분획물들은 암세포의 생육에 대하여 거의 억제활성을 나타내지 않았다. 에탄올 추출물들은 인체의 정상 간세포에 대하여 거의 세포독성을 나타내지 않았다. 참당귀의 디에틸 에테르 분획물들은 일당귀와 비교하여 20% 미만의 세포독성을 보여주었다. 참당귀와 일당귀 디에틸 에테르 분획물들의 0.5㎍/㎕ 첨가는 T세포와 B세포의 생육의 3~4배 정도 증가에 의한 면역활성을 보여주었다. 또한 참당귀의 디에틸 에테르 분획물(0.7㎍/㎕)이 ACE 활성을 98%까지 억제시켜 혈압을 조절할 수 있음도 증명되었다. TLC로부터, 두 개의 디에틸 에테르 분획물들은 참당귀와 일당귀의 활성 성분중의 하나로 알려진 umbelliferon을 함유함을 알 수 있었다. The ethanol extracts from Anglica gigas Nakai and Angelica acutiloba Kitagawa were fractionated to diethyl ether and aqueous partitions. Both partitions had strong antimutagenic effect on the MNNG (N-methyl-N-nitro-N-nitrosoguanidine) by Ames mutagenicity of MNNG with inhibition of 78~80%. The ethanol extracts from both species showed the inhibitory effect on the growth of several human cancer cell lines. Especially, the diethyl ether fraction from ethanol extracts was most effective on human hepatocellular carcinoma cells, inhibiting 90~95% of cell growth. However, the aqueous fractions had least inhibition activity on many cancer cells. There was little cytotoxicity on human normal liver cell by ethanol extracts. Diethyl ether fraction from Angelica gigas Nakai ethanol extract had cytotoxicity les than 20% on human normal liver cells, compared with that from Angelica acutiloba Kitagawa ethanol exract. The adding of 0.5 (g/ℓ) of diethyl ether fractions of Angelica gigas Nakai or Angelica acutiloba Kitagawa increased immune activity by enhacing human B and T cells up to three to four times. It was proven that diethyl ether fraction (0.7 g/ℓ) from Angelica gigas Nakai could control blood pressure by suppressing angiotensin converting enzyme activity up to 98%. From TLC, it was appeared that both of diethyl ether partitions had umbelliferon, known to one of active substances from Angelica gigas Nakai and Angelica acutiloba Kitagawa.

Comparison of Genetic Profiles and Prognosis of High-Grade Gliomas Using Quantitative and Qualitative MRI Features: A Focus on G3 Gliomas

Hong Eun Kyoung,Choi Seung Hong,Shin Dong Jae,Jo Sang Won,Yoo Roh-Eul,Kang Koung Mi,Yun Tae Jin,김지훈,Sohn Chul-Ho,Park Sung-Hye,Won Jae-Kyoung,Kim Tae Min,Park Chul-Kee,Kim Il Han,Lee Soon-Tae 대한영상의학회 2021 Korean Journal of Radiology Vol.22 No.2

Objective: To evaluate the association of MRI features with the major genomic profiles and prognosis of World Health Organization grade III (G3) gliomas compared with those of glioblastomas (GBMs). Materials and Methods: We enrolled 76 G3 glioma and 155 GBM patients with pathologically confirmed disease who had pretreatment brain MRI and major genetic information of tumors. Qualitative and quantitative imaging features, including volumetrics and histogram parameters, such as normalized cerebral blood volume (nCBV), cerebral blood flow (nCBF), and apparent diffusion coefficient (nADC) were evaluated. The G3 gliomas were divided into three groups for the analysis: with this isocitrate dehydrogenase (IDH)-mutation, IDH mutation and a chromosome arm 1p/19q-codeleted (IDHmut1p/19qdel), IDH mutation, 1p/19q-nondeleted (IDHmut1p/19qnondel), and IDH wildtype (IDHwt). A prediction model for the genetic profiles of G3 gliomas was developed and validated on a separate cohort. Both the quantitative and qualitative imaging parameters and progression-free survival (PFS) of G3 gliomas were compared and survival analysis was performed. Moreover, the imaging parameters and PFS between IDHwt G3 gliomas and GBMs were compared. Results: IDHmut G3 gliomas showed a larger volume (p = 0.017), lower nCBF (p = 0.048), and higher nADC (p = 0.007) than IDHwt. Between the IDHmut tumors, IDHmut1p/19qdel G3 gliomas had higher nCBV (p = 0.024) and lower nADC (p = 0.002) than IDHmut1p/19qnondel G3 gliomas. Moreover, IDHmut1p/19qdel tumors had the best prognosis and IDHwt tumors had the worst prognosis among G3 gliomas (p < 0.001). PFS was significantly associated with the 95th percentile values of nCBV and nCBF in G3 gliomas. There was no significant difference in neither PFS nor imaging features between IDHwt G3 gliomas and IDHwt GBMs. Conclusion: We found significant differences in MRI features, including volumetrics, CBV, and ADC, in G3 gliomas, according to IDH mutation and 1p/19q codeletion status, which can be utilized for the prediction of genomic profiles and the prognosis of G3 glioma patients. The MRI signatures and prognosis of IDHwt G3 gliomas tend to follow those of IDHwt GBMs.

Rapid quantification of alpha emitters in low- and intermediate-level dry radioactive waste

Park, Tae-Hong,Jeon, Eul-Hye,Choi, Yong Sul,Park, Jong-Ho,Ahn, Hong Joo,Park, Yong Jun Springer-Verlag 2016 JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY Vol.307 No.1

Radiogenomics correlation between MR imaging features and major genetic profiles in glioblastoma

Hong, Eun Kyoung,Choi, Seung Hong,Shin, Dong Jae,Jo, Sang Won,Yoo, Roh-Eul,Kang, Koung Mi,Yun, Tae Jin,Kim, Ji-Hoon,Sohn, Chul-Ho,Park, Sung-Hye,Won, Jae-Kyung,Kim, Tae Min,Park, Chul-Kee,Kim, Il Han Springer-Verlag 2018 EUROPEAN RADIOLOGY Vol.28 No.10

간경변증 환자에서 신장 Doppler 초음파 - Resistive Index의 예후적 가치

박창영,조용균,김향,이상종,정을순,이영래,김병익,전경홍,유종현 대한소화기학회 1998 대한소화기학회지 Vol.30 No.2

Background/Aims: Kidney dysfunction in cirrhosis is a well recognized complication that often appears to develop abruptly in previously nonazotemic patients. Intrarenal vasoconstriction is an early hallmark of this functional renal failure because e;evatecl serum creatinine is a late feature of the hepatorenal syndrorne. Resistive index(RI) is the most widely used for estimation of intrarenal arteriolar vascular resistance. We have applied renal dup]ex Doppler ultrasonography to identify this early renal vasoconstriction in nonazotemic patients with liver cirrhosis. Methods: We prospectively measured RI, kidney and liver function and plasma level of renin activity, aldosterone and antidiuretic hormone in 12 healthy subjects, 13 cirrhotic patients without ascites, 22 cirrhotic patients with ascites, 7 cirrhotic patients with ascites and renal falure. Tnen, patiens were followed for 6 months. The incidence of renal failure in each groups were recored and ccrrelated with RI, liver and renal function. Results: RI was significantly increased in patients with cirrhosis(0.68±0.06) compared with healthy subjects(0.39±0.04). In 42 cirrhotic patients, it was significantly increased in patients with ascites(0.69±0.05) compared with patients without ascites(0.64±0.05) and correlated significantly to creatinine clearance(Cr=-0.61, p$lt;0.05). RI was significantly increased in patients with intractable ascites(0.72±0.04) compared with diuretics responded ascites(0.68±0.05). Kidney dysfunction subsequently developed in six(37%) of 16., who had an clevated RI.(≥0.70) In contrast, only one(4%) of 26 patients with a normal RI had kidney dysfunction. Conclusions: Renal duplex Doppler ultrasonography can identify high risk group for subsequenl development of renal dysfunction and be useful for treatment of ascites in cirrhotic patients with nonazotemia by detecting renal vasoconstriction.

유암종에 대한 임상적 고찰

박창영,이상종,김병익,정을순,김기택,성기철,전경홍,황기은,장남수,편유장 대한소화기학회 1998 대한소화기학회지 Vol.30 No.2

Background/Aims: The term, carcinoid, is derived from $quot;Karznoid$quot; coined by Oherndorfer in 1907, which means carcinoma like lesion with no malignant potential. However, it is now generally accepted that these innocuous neoplasms potentially can produce widespread metastasis. Although the carcinoid tumor is relatieve]y rare, it continue to be of special clinical interest because of the endocrine potential, the malignant potential and the recent appearance of the composite carcinoma-carcinoid tumor. Methods: We reviewed the recorded clinical rnanifestations of twenty-two patients with carcinoid tumor, which had been treated from the Kang Book Samsung Hospital for 17 years frorn August 1979 to Septernher 1996. Results: The peak incidence was in the 5th decade occup- ying 9 cases(42%) and male predominence with a ratio of 2.1:1. The common site of the tumors was the rectum(8 cases) and appendix(5 cases). The incidence ot' carcinoid tumors according to the embryologic origin were foregut 6 cases(27%), midgut 7 cases(32%), hindgut 9 cases(41%). The hepatic metatasis was presented in 3 cases. There was no case with classic carcinoid syndrome. Thirty-two percent cases had carcinoma with carcinoid tumor, and nine percent cases had malignant carcinoid tumor. Conclusions: Comparing the age and tumor location, some difference was observed between 22 cases carcinoid tumor experienced at our hospital and those of foreign studies, but other difference was not observed.

항생제의 처리가 적변발생에 미치는 영향

Park Hong-Woo,Kim Hyeon-Gil,Kim Bo-Ra,Choi Jae-Eul,Jin Xuan-Ji 한국작물학회 2006 한국작물학회 학술발표대회 논문집 Vol.2006 No.-

작물보호(作物保護) 국제(國際) 심포지움 및 학술연구(學術硏究) 발표요지(發表要旨) : 잡초방제, 생태, 분류 (다이아몬드 볼룸, 2F) ; 유효성분의 용출조절에 의한 이앙동시처리 제초제의 약해경감 및 잡초방제효과

유홍재 ( Hong Jae Yoo ),정봉진 ( Bong Jin Chung ),명을재 ( Eul Jae Myung ),송재영 ( Jae Young Song ),박채현 ( Chae Hyun Park ) 한국잡초학회 2000 한국잡초학회 별책(학술대회 초록집) Vol.20 No.2