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Laminar Viscous Flow past a Flat Plate with Finite Thickness
KIM, Moon-Uhn 朝鮮奬學會 1974 學術論文集 Vol.4 No.-
A study is made of laminar viscous flow past a semi-infinite flat plate with finite thickness, set parallel to a uniform strm. An asym¬ptotic solution of the Navier-Stok es equations is constructed on the basis of high-Reynolds-number approximations. The total drag coef¬ficient Cn for a flat plate of thickness 2a immersed in a uniform flow U is shown to be given by ▷수식입력(원문을 참조하세요)◁where R= Ux^(*)/v and x=x^(*)/a (x^(*) being the distance along the plate and v the kinematic viscosity).
문재곤,오성훈,최중언,김영수,정상섭,이규창 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.1
A series of 70 lumboperitoneal shunt performed at Yonsei univesity Severance hospital was reviewed. The clinical indications for this procdures were communicating hydrocephalus, CSF fistulas, benign intracranial hypertension and bulging craniectomy site. There were several complications such as shunt migration, obstruction, infection and nonfucnctioning. Wound dehiscence, epidural hematoma and inguinal hernia were also obseved after shunting. This procedure is completely extracranial and diminished intracranial complications, thereby significantly reducing morbidity and mortality. Good results were reported due to easy insertion, short operation time and reduced complications. This report documented the efficacy of lumboperitoneal shunt and literatures were reviewed.
임상적 비기능성 뇌하수체선종의 내분비학적 및 형태학적 특징
김태승,정현주,허갑범,이현철,임승길,이은직,김경래,송영득,남문석,이규창,조재화,최중언,정상섭,김선호 대한내분비학회 1994 Endocrinology and metabolism Vol.9 No.3
Forth-nine patients with clinically nonfunctioning pituitary adenomas were evaluated clinically, endocrinologically and morphologically in this study. The results obtained were as follows. 1) The mean age was 47.1 years(range 23 to 76 years), and 22 were male(44.9%) and 27(55.1%) female. 2) The major clinical manifestations of male patients were visual disturbance(72.7%), headache(54.5%), loss of libido(45.5%), but those of female visual disturbance(59.6%), headache(48.1%), amenorrhea(48.1%), loss of body hair(25.9%), and galactorrhea(22.2%). 3) All were macroadenomas evaluated by CT scan, and in the male patients 16(72.7%) were grade Ⅲ and 6(27.3%) grade Ⅳ by Hardy classification, and in the female patients 6(22.2%) were grade Ⅱ, 12(44.4%) grade Ⅲ, and 9(33.3%) grade Ⅳ. 4) The elevation of serum prolactin were observed 7(31.8%) out of male, and 24(88.9%) of female. 5) Combined stimulation test revealed that GH insufficiency was 89.6%, ACTH 58.9%, LH 58.7%, FSH 51.1 %, and TSH 50.0% and hormone insufficiency more than 4 pituitary hormone was 54.2%. 6) Prolactin response to TRH decreased in 12(70.6%) of 17 patients with normal basal prolactin, and 19(76.0%) of 25 with elevated prolactin. 7) Immunohistochemistry revealed that null cell adenoma was 57.1%, gonadotrope adenoma 26.5%, plurihormonal adenoma 8.0%, silent corticotrope adenoma 4.0%, thyrotrope adenoma(2.0%), and lactotrope adenoma(2.0%). 8) The ultrastructural characteristics examined by electron-microscopy were similar despite of immunohistochemical differences. In summary, the prevalance of clinically nonfunctioning pituitary adenoma was middle aged men and women, and their main symptoms were visual disturbance and headache. Hyperprolactinemia and pituitary hormone insufficiency more than 4 hormone were observed commonly. Most of them were null cell adenoma and gonadotrope adenoma examined by immunohistochemistry. Further study using modern techniques: cell culture, subunit-immunostaining. And Northern blot analysis of mRNA for pituitary hormone or subunit, will be needed to clarify null cell adenomas(J Kor Soc Endocrinol 9: 220-212, 1994).
성장호르몬과 프로락틴분비 뇌하수체선종의 In Situ Hybridization에 의한 분석
김태승,정현주,허갑범,이현철,임승길,이은직,김경래,남문석,이규창,김선호,조재화,최중언,정상섭 대한내분비학회 1994 Endocrinology and metabolism Vol.9 No.2
A non-isotopic in situ hybridization method with biotin-labelled oligonucleotide probes was used to examine growth hormone(GH) and prolactin(PRL) gene expression in 32 patients with pituitary adenomas; 13 were prolactinomas, 8 GH secreting adenomas, and 11 mixed GH and PRL secreting adenomas. Positive immunostaining for GH was found in all patients with GH secreting adenomas, and mixed GH and PRL secreting adenomas. Positive immunostaining for PRL was found in all patients with prolactinomas and 9(81.8%) of 11 mixed GH and PRL secreting adenomas, 5(62.5%) of 8 GH secreting adenomas. Immunohistochemistry revealed that 13 were lactotrope adenomas, 5 somatotrope adenomas, and 14 GH and PRL cell adenomas. In situ hybridization revealed that GH mRNA expression was found in all the patients with somatotrope adenomas and GH and PRL cell adenomas, and 6(46.1%) of 13 lactotrope adenomas. PRL mRNA expression was 100% in lactotrope and GH and PRL cell adenomas, and 4(80.0%) of 5 somatotrope adenomas. The patients with a clinical diagnosis of acromegaly had detectable PRL mRNA in their neoplasm and it is suggested that the PRL cells in the adenomas did not result from dedifferentiation, but from the neoplastic stimulus for some mixed tumors probably occurred in cells previously committed to produce PRL and GH. In lactotrope adenomas, the PRL cells of the patients without expression of GH mRNA may be arised from cells programmed to secrete PRL or precussor PRL cells rather than from mixed GH-PRL cells. The finding that some patients produced mRNA detectable by in situ hybridization, but no hormone detectable by immunohistochemistry within tumor was suggested of a silent adenoma. These observations indicated that in situ hybridization studies may improve the classification of pituitary adenomas and may provide a precise knowledge of the biology of these neoplasms.(J Kor Soc Endocrinol 9:82-92, 1994)
문재곤,허승곤,최중언,정상섭,이규창,김동익,서정호 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.6
Radiotherapy is a standard postoperative treatment for various cerebral neoplasms. However, radiation has the potential to produce severe injury to normal brain tissue in and around the tumor bed. The authors encountered 7 patients with delayed cerebral necrosis. These unacceptable complication prompted us to analyze cases with such a complication particularly in regard to the differential diagnosis between the recurrence of the tumor and radiation necrosis of the brain. This article summarizes factors related to the radiation necrosis, including clinical observations and treatment.
Chung, Moon-Young,Park, Young-Seok,Kim, Dong-Seok,Choi, Joong-Uhn The Korean Neurosurgical Society 2009 Journal of Korean neurosurgical society Vol.46 No.3
Intraventricular hemorrhage long after successful encephaloduroarterio synangiosis (EDAS) is very rare. The effect of revascularization surgery for preventing hemorrhagic event of moyamoya disease remains controversial. We report a 17-year-old female with intracerebral hemorrhage and intraventricular hemorrahge 10 years after successful EDAS. Even though cerebral vessels angiography showed good collateral circulations without specific weak points, a cerebral hemorrhage could occur in patient with ischemic type of moyamoya disease long after successful indirect bypass operations. Good collateralization of cerebral angiography or magnetic resonance perfusion image after indirect bypass surgery would ensure against ischemic symptoms, not a hemorrhage. And, thus a life-time follow-up strategy might be necessary even if a good collateral circulation has been established.