http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
이승아,배자성,김기환,김지일,안창혁,박우찬,송병주,정상설,김정수,Seung Ah Lee,M.D.,Ja Seong Bae,M.D.,Kee Hwan Kim,M.D.,Ji Il Kim,M.D.,Chang Hyuck An,M.D.,Ph.D.,Woo Chan Park,M.D.,Ph.D.,Byung Joo Song,M.D.,Ph.D.,Sang Seol Jung,M.D 대한갑상선-내분비외과학회 2007 The Koreran journal of Endocrine Surgery Vol.7 No.2
Purpose: Endoscopic surgery to treat thyroid neoplasm was developed to solve the aesthetic problems that resulted from conventional open surgery. Although endoscopic thyroidectomy was initially performed in patients with benign thyroid neoplasm, its use has recently been extended to patients with Graves's disease and early cases of thyroid cancer.The purpose of this study was to determine whether this surgical approach is feasible and safe for the treatment of thyroid cancer. Methods: Between December 1999 and April 2006, 132 thyroid cancer patients at our institution were treated by either conventional thyroidectomy or endoscopic thyroidectomy. Endoscopic thyroidectomy was conducted using a gasless anterior neck skin lifting method. The inclusion criteria for endoscopic thyroidectomy in thyroid cancer patients included a tumor size of less than 2cm, absence of extrathyroidal extension, absence of cervical lymph node metastasis, and well differentiated cancers. Results: We performed endoscopic thyroidectomy in 29 thyroid cancer patients. There were no significant differences in operative time, the amount of drainage and the number of retrieved lymph nodes between conventional thyroidectomy and endoscopic thyroidectomy. In addition, although endoscopic thyroidectomy was associated with more complications, it was also associated with a shorter hospital stay. Conclusion: The completeness of surgical resection conducted via an endoscopic thyroidectomy may be comparable to that of conventional surgery, however, a larger series and longer follow-up evaluation are necessary for definitive conclusions to be drawn about its oncologic validity. (Korean J Endocrine Surg 2007;7:103-106)
생체 내에서 배양한 각막윤부 상피세포 이식술의 장기 경과 관찰 결과
천현철,신동민,이동준,박우찬,Hyun Chul Cheon,M,D,Dong Min Shin,M,D,Dong Joon Lee,M,D,Woo Chan Park,M,D 대한안과학회 2008 대한안과학회지 Vol.49 No.3
`Purpose: To investigate the characteristics and the results of long-term follow-up of limbal epithelial cells cultivated in vivo on amniotic membranes (LIVAM) in corneal limbal deficiency. Methods: Twenty-two eyes of twenty-two patients diagnosed with corneal limbal deficiency underwent transplantation of in vivo cultivated corneal limbal epithelial cells on the amniotic membrane. Biopsy and immunohistochemical staining (AE5, MUC5AC) of the amniotic membrane cultivated for one week were performed to verify that the cultivated epithelial cells on the amniotic membrane were corneal epithelial cells. Impression cytology was performed to evaluate the characteristics of the transplanted corneal limbal epithelial cells at postoperative 1 week, 3 months, 6 months, and 1 year. Results: Successful epithelial growth was observed on the amniotic membrane at one week. The epithelial cells were confirmed to be corneal epithelial cells by immunohistochemical staining. Transplanted in vivo cultivated corneal epithelial cells were confirmed to have corneal specificity by impression cytology and immunohistochemical staining at postoperative 1 week, 3 months, 6 months, and 1 year. Conclusions: In vivo cultured corneal epithelial cells showed morphological and immunohistochemical findings similar to those of normal corneal epithelial cells. Transplanted in vivo cultivated corneal epithelial cells were maintained and showed the characteristics of corneal epithelial cells. Transplantation of in vivo cultivated corneal limbal epithelial cells can be performed to reconstruct the corneal limbus in treating corneal limbal deficiency. `
김동주,장이찬,최재운,박진우,Dong-Ju Kim,M.D.,Lee-Chan Jang,M.D.,Jae-Woon Choi,M.D. and Jin-Woo Park,M.D. 대한갑상선-내분비외과학회 2012 The Koreran journal of Endocrine Surgery Vol.12 No.3
Clear cell renal cell carcinoma (RCC) is the most common histological subtype of malignant renal tumors. Although RCC frequently metastasizes to many organs, it rarely metastasizes to the thyroid gland without evidence of other organ involvement. We report a case of a metastatic renal cell carcinoma to the thyroid gland, which was misdiagnosed preoperatively as a follicular neoplasm from the fine needle aspiration cytology.
정파종,김성우,박찬현<SUP>1<.SUP>,김한준,Pa Jong Jung,M.D.,Sung Woo Kim,M.D.,Chan Hyun Park,M.D.<SUP>1 <.SUP>and Han Joon Kim,M.D. 대한갑상선-내분비외과학회 2003 The Koreran journal of Endocrine Surgery Vol.3 No.1
The enlarged parathyroid glands associated with chronic renal failure were recognized during the 1930's. The number of patients on long-term hemodialysis due to chronic renal failure is steadily increasing and the hyperparathyroid state certainly became a clinical problem in the dialysis population. The physiologic mechanisms leading to secondary hyperparathyroidism are multifactorial with renal phosphate retention, skeletal resistance to parathyroid hormone (PTH) action and impairment vitamin D metabolism being some of the known factors. Despite intensive medical management however inadequate control of parathyroid hyperplasia may necessitate surgical intervention. The goal of surgical therapy is to resect sufficient tissue to reverse the hyperparathyroidism without rendering the patient permanently hypoparathyroidism. We experienced a case of secondary hyperparathyroidism and reported its result of total parathyroidectomy, autogenous transplantation and cryopreservation of parathyroid gland. (Korean J Endocrine Surg 2002;2:57-62)
김민기,최영수,김기현,배자성,이동호,성기영,김정수,박우찬,Min-Ki Kim,M,D,Young-Soo Choi,M,D,Ki-Hyun Kim,M,D,Ja-Sung Bae,M,D,Dong-Ho Lee,M,D,Ki Young Sung,M,D,Jung-Soo Kim,M,D,and Woo-Chan Park,M,D 대한갑상선-내분비외과학회 2009 The Koreran journal of Endocrine Surgery Vol.9 No.1
Purpose: This study was performed to readjust the clinical implications of a nonrecurrent laryngeal nerve by assessing the reported Korean cases of a nonrecurrent laryngeal nerve. Methods: We analyzed the cases of nonrecurrent laryngeal nerve that have been reported in Korea between 1997 and 2008 by reviewing the literature. An internet search was conducted in the NDSL (National Digital Science Library) and the Korean Medical Database. Results: The data included 3 men and 25 women with an average age of 45.1 (age range: 28∼58). All the cases were right-sided, and the incidence rate was 0.38% and 0.86% in two articles, respectively. There was a type I variation in 4 cases (17.4%), type IIa in 19 cases (82.6%), and the others are unknown. Twenty-five cases (89.3%) had the vascular anomaly called arteria lusoria. Only 8 cases (28.6%) were preoperatively predicted as possibly having a nonrecurrent laryngeal nerve. Iatrogenic nerve injury developed in 1 case (3.57%) with a type I variation during the postoperative period. Conclusion: A similar tendency for the incidence rate, the genderratio, the type distribution and vascular anomaly was observed when comparing the Korean reports with those reports of overseas. The nonrecurrent laryngeal nerve can be preoperatively predicted if proper attention is given when vascular anomaly is noted on CT or USG, and injury will be avoided by intraoperatively following the standard operation technique. There is currently an increasing incidence of thyroid diseases, and so adequate attention must be given to the possibility of a nonrecurrent laryngeal nerve and its management. (Korean J Endocrine Surg 2009;9:24-29)
김형래,시윤,이연수<SUP>1<.SUP>,김정수,전해명,박우찬,Hyung Rae Kim,M.D.,Youn Si,M.D.,Youn Soo Lee,M.D.<SUP>1<.SUP>,Jung Soo Kim,M.D.,Hae Myung Jeon,M.D. and Woo Chan Park,M.D. 대한갑상선-내분비외과학회 2007 The Koreran journal of Endocrine Surgery Vol.7 No.2
Purpose: It is well known that cyclooxygenase-2 (COX-2) is associated with carcinogenesis in many human cancers. In thyroid cancers, COX-2 expression in aging patients is known as a powerful prognostic factor of differentiated thyroid cancer. Therefore, in this study, we investigated the expression of COX-2 in cases of papillary thyroid cancer (PTC), as well as its association with other prognostic factors of thyroid cancer. Methods: A total of 213 cases of papillary thyroid cancer were enrolled in this study and their clinicopathological characteristics were investigated retrospectively by a review of medicalrecords. Immunohistochemical staining for COX-2 was performed in the malignant tissue of the cases and the resultsof were then evaluated to determine if they were associated with other prognostic factors. Results: The mean age of patients was 46 years (Range: 17∼77 years old) and the tumor sizesranged from 0.1 to 5 cm (mean 1.2±0.9 cm). The pathological findings were as follows; thyroid capsule invasion in 101 patients (47%), lymph node metastasis in 76 patients (36%), multiplicity in 47 patients (22%), and bilaterality in 36 patients (17%). Positive results of immunohistochemical staining for COX-2 were noted in 131 patients (62%), however, the statistical analyses showed no significant association between COX-2 expression and other prognostic factors of papillary thyroid cancer. Conclusion: No association of COX-2 expression and prognostic factors of papillary thyroid cancer were found in this study. However, a larger prospectivestudy with survival analyses would provide a better understanding of thesignificance of COX-2 expression in cases of papillary thyroid cancer. (Korean J Endocrine Surg 2007;7:75-79)
김영균,김기환,안창혁,임근우,박우찬,송병주,정상설,김정수,장은덕<SUP>1<.SUP>,이은정<SUP>1<.SUP>,Young Kyun Kim,M.D.,Kee Hwan Kim,M.D.,Chang Hyeok Ahn,M.D.,Keun Woo Lim,M.D.,Woo Chan Park,M.D.,Byung Joo Song,M.D.,Sang Seol Jung,M.D. 대한갑상선-내분비외과학회 2006 The Koreran journal of Endocrine Surgery Vol.6 No.2
Anaplastic thryoid carcinomas are very aggressive and lethal solid tumors; they sometimes show microscopic vascular invasions, but they rarely result in tumor thrombus in the internal jugular vein or in the other great veins of the neck. We encountered a 64-year-old woman with anaplastic thyroid carcinoma and a tumor thrombus that extended from the Lt. internal jugular vein to the innominate vein. Palliative total thyroidectomy, modified radical neck dissection and segmental resection of the Lt. internal jugular vein were done, along with removal of the intravascular tumor thrombus. We recommended postoperative radiotherapy and chemotherapy, but the patient refused additional treatments. We report here on this case for which we first experienced anaplastic thryoid carcinoma associated with tumor thrombus of the internal jugular vein. (Korean J Endocrine Surg 2006;6:102-105)
갑상선암의 내시경 갑상선 절제술에서 근전절제술 및 전절제술의 임상적 비교
유한모,김태원,배자성<SUP>1<,SUP>,조항주,김기환,안창혁,박우찬<SUP>2<,SUP>,이동호<SUP>3<,SUP>,김정수,Han Mo Yoo,M,D,Tae Won Kim,M,D,Ja Sung Bae,M,D,<SUP>1<,SUP>,Hang Joo Cho,M,D,Kee Hwan Kim,M,D,Chang Hyuk An,M,D,Woo Chan Park,M 대한갑상선-내분비외과학회 2009 The Koreran journal of Endocrine Surgery Vol.9 No.4
Purpose: The aim of this study was to evaluate and compare the surgical outcomes of endoscopic total and near-total thyroidectomies in patients with thyroid cancer. Methods: Between February 2000 and January 2009, among 387 patients who underwent endoscopic thyroidectomy in our hospital, we evaluated 50 patients who underwent endoscopic total or near-total thyroidectomy. Thirty- five and 15 patients underwent endoscopic total thyroidectomy and near-total thyroidectomy, respectively. We analyzed the patients' clinicopathologic characteristics and post-operative complications between the two groups. Results: The mean size of tumors was 1.08 cm (range, 0.1∼3.5 cm) and the mean operative time was 192 minutes. Forty-nine tumors were papillary cancers and 1 tumor was a follicular cancer. Two patients in the endoscopic total thyroidectomy group underwent re-operation because of bleeding. In the near-total thyroidectomy group, one patient had transient hypocalcemia and one patient had temporary recurrent laryngeal nerve palsy. In the total thyroidectomy group, nine patients had transient hypocalcemia and one patient had temporary recurrent laryngeal nerve palsy. There was no statistical difference in the post-operative complicationrates between the two groups (P=0.254 for hypocalcemia and P=0.470 for injury to the recurrent laryngeal nerve). Conclusion: Based on our experience, endoscopic total thyroidectomy is a safe and feasible alternative to endoscopic near-total thyroidectomy. (Korean J Endocrine Surg 2009; 9:201-205)