Interleukin-2가 호산구 생존에 미치는 영향과 기전에 관한 연구

김효석 ( Hyo Seok Kim ),이영목 ( Young Mok Lee ),최영수 ( Young Soo Choi ),김경호 ( Kyung Ho Kim ),임건일 ( Geon Il Im ),문승혁 ( Jeong Sung Whan ),정성환 ( Moon Seung Hyug ),김현태 ( Hyeon Tae Kim ),어수택 ( Uh Soo Taek ),김용훈 대한결핵 및 호흡기학회 1996 Tuberculosis and Respiratory Diseases Vol.43 No.3

방사선 조사후 아크릴릭 레진의 물성변화

이용근,이건일,박영준,변호영 원광대학교 생체재료·매식연구소 1995 원광생체재료·매식 Vol.4 No.2

To investigate the effect of high dose irradiation on the mechanical properties. dental acrylic resin specimens were irradiated and the Vickers hardness number(VHN) and the 3-point flexure strength(FS) were measured before and after irradiation. Five kinds of acrylic resins were studied. Two(VRS. PS2) were heat cured denture base resins. one(VSC) was chemically cured denture base resin and the other two(ORJ, VOP) were orthodontic resins. The acrylic resin specimens were made according to the manufacturer's instructions and were finally polished with Microcloth (Buehler). Among ten specimens of each material. five specimens were irraditated with 100 Gy using a linear accelerator (Mitsubishi 6 MV), and the others were not. The specimens were immersed in 37℃ D.W. for 48 hours before testing. Each specimens the VHN was measured 10 times. Their FS was measured with an universal testing machine (Instron 4302, England), with a cross-head speed of 5 mm/min. The VHNs of heat cured resins were 21.52∼25.55 kg/㎟ before irradiation and 19.93∼26.58 kg/㎟ after irradiation. Those of chemically cured resins were 11.28∼16.6kg/㎟ before irradiation and 11.3∼14.3 kg/㎟ after irradiation. The VHNs of heat cured acrylic resins were significantly higher than those of chemically cured resins were significantly higher than those of chemically cured resins before and after irradiation(p<0.05). VHN of VRS was significantly increased after irradiation, and those of VOP and PS2 were significantly decreased after irradiation (p<0.05). The FS of resins studied were 6.7∼8.0 kg/㎟ before irradiation and 6.5∼8.4 kg/㎟ after irradiation. The FS of VSC and VRS increased after irradiation and those of VOP, ORJ and PS2 decreased after irradiation, but the results were not statistically significant. Before irradiation, the FS of heat cured resins were somewhat higher than those of chemically cured resin, but not statistically significant, and after irradiation the FS of heat cured resins were significantly higher than those of orthodontic resins. In conclusion. high dose irradiation did not result in consistent changes in mechanical properties.

경두개촬영법에서 조사각도변화에 의한 하악과두의 모양에 관한 실험적 연구

이건일,변호영 원광대학교 생체재료·매식연구소 1995 원광생체재료·매식 Vol.4 No.2

The author has evaluated the transcranial oblique lateral images of the mandibular condyle according to the angulation of the radiation projection. The lead foils were attached to both condylar poles and two thin wires were attached to the superior border and posterior border of the condyle. The mandibular condyle was located on the device designed specially. The materials consisted of 56 transcranial oblique lateral projections. The results were as follows: 1. It was possible to find the point of the retroepicondyle at angles of H-1OVO. HOVO, H-1OV5, HOV5, HOV1O and H1OVO - H1OV35(H:horizontal angulation. V:vertical angulation). 2. It was impossible to find the osteosclerotic line located in the anterior portion of the condyle on transcranial oblique lateral view at angles of H2OVO, H2OV5, H3OVO. H3OV5, H3OV1O. The length of the osteosclerotic line was positive horizontal angulation. but the distance between the osteosclerotic line and the superior border of the condyle was getting closer. 3. When the vetical angulation increased. the smooth posteior border line of the condyle was getting angulated with the increase of the positive horizontal angulation and getting curved sharply with the increase of the negative horizontal angulation. 4. We might misinterpret the shape of the medial pole as the ostophyte seen in osteoarthrosis with the increase of the negative horizontal angulation. 5. The inclination and the distance between both condylar poles were getting increased with the increase of the horizontal and the vertical angulation.

지수분포를 따르는 가속수명자료의 적률추정법에 기초한 경험적 베이즈 예측분석

조건호,이우동,하일도 慶山大學校 基礎科學硏究所 1997 基礎科學 Vol.1 No.2

본 논문은 지수수명분포에서 제2종 중도절단된 가속수명자료를 이용하여 고장률의 사전분포의 평균을 알 때, 정상조건하에서 하나의 미래 관찰치의 예측문제를 사전분포의 모수에 대하여 적률추정량에 기초한 불편추정량(unbaised estimator)을 이용하는 경험적 베이즈 접근방법을 적용시켜 경험적 베이즈 예측분포와 예측구간에 대하여 연구하였다. In accelerated life tests(ALTs), the failure time of a test item is observed under high stress conditions, and based on these data, one intrests statistical inference on the parameters of lifetime distribution at the normal stress. Under the type-II censoring, we assume that the life distribution is exponential distribution. When the information on the prior is partially known, we device the empirical Bayesian analysis of ALTs data in order to obtain the empirical Bayesian predictive density and predictive intervals for a future observation under the normal stress level.

지수분포를 따르는 가속수명자료의 최우추정법에 기초한 경험적 베이즈 예측분석

조건호,이우동,하일도 慶山大學校 基礎科學硏究所 1997 基礎科學 Vol.1 No.2

본 논문은 지수수명분포에서 제2종 중도절단된 가속수명자료를 이용하여 고장률의 사전분포의 평균을 알 때, 정상조건하에서 하나의 미래 관찰치의 예측문제를 사전분포의 모수에 대하여 최우추정량(Maximun Likelihood estimator)을 이용하는 경험적 베이즈 접근방법을 적용시켜 경험적 베이즈 예측분포와 예측구간에 대하여 연구하였다. In accelerated life tests(ALTs), the failure time of a test item is observed under high stress conditions, and based on these data, one intrests statistical inference on the parameters of lifetime distribution at the normal stress. Under the type-II censoring, we assume that the life distribution is exponential distribution. When the information on the prior is partially known, we device the empirical Bayesian analysis of ALTs data in order to obtain the empirical Bayesian predictive density and predictive intervals for a future observation under the normal stress level.

기술가치 평가모델의 비교 및 분석

兪日根,李在勳 弘益大學校 科學技術硏究所 2001 科學技術硏究論文集 Vol.12 No.-

Since the technology is one of the important factor for the development of countries or companies, evaluation of technology became essential for investment on venture company, technology trading and M&A. The appropriate evaluation of technology is so important yardstick of competence of business that, in this thesis, the theories and the present conditions of technology evaluation model in several institutes are compared and analysed and also the desirable direction for the future right model are suggested. Technology evaluation model is basically composed of three parts: cost-market-income approach method, technology factor method, real option method. We have to choose proper model among several methods because there are various technology evaluation methods and they have different merits and demerits. So that, due to some limits for each model, there is no complete one which can drive the right valuation by itself at one time. Thus, right valuation seems to be required that several different methods of each model should be applied and analysed at the same time and then decide the right answer that satisfies the suggested conditions.

폐혈관상이 유지된 선천성 낭성 선종양 기형

배일헌,한기석,차상훈,김성진,박길선,이건국,홍장수 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.2

선천성 낭성 선종양 기형은 태생 16주 이후 말단세기관지의 형성이 중단되어 미성숙기관지들과 중배엽성분들이 과도하게 증식하여 발생하는 드문 선천성 폐질환이다. CT소견은 낭종의 크기 숫자, 내용물 등에 따라 다양하나, 병변내에 정상적인 폐혈관이 보인 예는 전세계적으로 보고된 적이 없었다. 저자들은 역동적 흉부 CT상 균일한 저음영의 병변내에 정상 폐혈관상이 유지된 선천성 낭성 선종양 기형 1예를 경험하였기에 보고한다. Congenital cystic adenomatoid malformation(CCAM) is a rare pulmonary disease that is thought to be developed by abnormal proliferation of immature alveoli and other mesenchymal component from the abrupt halting of the terminal alveoli formation after 16 weeks of gestation. On CT scan, there are no consistencies regarding to size, numbers, and its contents but no cases were reported in past showing normal pulmonary vascularities. We reports a case of CCAM that showed normal pulmonary vascularities within the hypodense lesions on a dynamic chest CT

병식 평가 척도-한국판(SUMD-K)의 신뢰도와 타당도 검증

송지영,김기태,이서경,김용희,노준호,김종우,장환일,반건호,강원섭 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.4

Objectives : This study was conducted to evaluate the reliability and the validity of the Korean version of the Scale to Assessment Unawareness of Mental Disorder (SUMD-K). Methods : The subjects were 55 schizophrenic patients between ages of 26 and 58 who were recruited from the psychiatric unit of the university hospital and the out-patient clinic. The SUMD-K and insight scale of PANSS were applied to the patients. Results : The range of inter-rater (Spearman's rho) of the general items of SUMD-K were .97-.98 on the current illness and .58-.98 on the past illness. The correlation coefficient between the sum and the general items of the SUMD-K showed high scores. The concurrent validity between SUMD-K and insight item of PANSS was high (scores between .59-.96). However,the reliability and the validity of the attribution items of symptoms showed low scores compared to the current symptoms. Conclusion : The SUMD-K was confirmed in its reliability and validity. It can be a useful clinician-rating scale for evaluating insight in schizophrenic patients as well as patients with other neuropsychiatric conditions.

An unusual case of scabies involving toenail in an infant

( Geon-jong Lee ),( Sang-kyung Lee ),( Il-jae Lee ),( Kyung-hwa Nam ),( Seok-kweon Yun ),( Han-uk Kim ),( Jin Park ) 대한피부과학회 2022 대한피부과학회 학술발표대회집 Vol.73 No.2

Furan, phenolic, and heptelidic acid derivatives produced by Aspergillus oryzae

Lee, Minji,Cho, Jeong-Yong,Lee, Yu Geon,Lee, Hyoung Jae,Lim, Seong-Il,Lee, So-Young,Nam, Young-Do,Moon, Jae-Hak Korean Society of Food Science and Technology 2016 Food Science and Biotechnology Vol.25 No.5

Eleven compounds, including a new sesquiterpene, were isolated from the culture medium of Aspergillus oryzae incubated with capsaicin. The structure of the new compound was determined to be 1,3,5a,6,7,8,9,9a-octahydro-9-hydroxy-9-(hydroxymethyl)-6-isopropyl-1-oxobenzo[c]oxepine-4-carboxylic acid, a heptelidic acid derivative. In addition, 10 known compounds were identified, namely 5-(hydroxymethyl)-3-furancarboxylic acid (flufuran), 3-hydroxypropanoic acid, 5-(hydroxymethyl)-2-furancarboxylic acid, 2-(4-hydroxyphenyl)-ethanol, 4-hydroxybenzoic acid, vanillic acid, 3,4-dihydroxybenzoic acid, 2-furanol, hydroheptelidic acid, and trichoderonic acid A, using spectroscopic data from nuclear magnetic resonance and electrospray ionization-mass spectroscopy.