경북대학교 병원 교정과에 내원한 부정교합 환자의 분포 및 변동추이

권오원,경희문,곡덕부,성재현,박동옥 대한치과교정학회 1989 대한치과교정학회지 Vol.19 No.3

1795 patients who visited orthodontic department from 1979 to 1987, were surveyed on the yearly tendency of patient distribution and state of Angle's classification. The results were as follows: 1. There was increased visiting rate of patient per year and higher visiting rate in female than in male. 2. 8-15 age group was 70.3% in total visiting patients and over 20 age group was 10.8%, under 7 age group was 7.3%. 3, Class I malocclusion was 26.3%, Class II div 1 was 31.0%, Class II div 2 was 1.6% and Class III was 41.1% in total visiting pateint. 4. There was increased tendency to be received preventive treatment than fixed treatment and increased extracting rate per year in fixed treatment. 5. There was increased tendency for the number of the patient to be received orthognathic surgery.

國産스테인레스鋼線系 矯正用線材의 開發과 物理的 性質에 關한 硏究

권오원,성재현,이기대,경희문 대한치과교정학회 1989 대한치과교정학회지 Vol.19 No.2

The physical properties of seven sizes of control groups and experimental group in stainless steel orthodontic wires were studied in tension, hardness, bending, torsion and observation of microstructure. The wires (0.40 - 0.90mm dia.) of round type were tested in the as-received condition. The wires of control groups were TRU-CHROME and REMANIUM, and experimental group was SK wire which was developed by ourselves and made in Korea. The results were as follows: 1. The chemical compositions of control groups and experimental group were austentie stainless steel wires of SOS 304. 2. Higher values of tensile and yield strength in tension were control group I, experimental group, control group II. Maximum tensile and yield strength of experimental group were 203.63 ±1.41kg/mm²in 0.70mm diameter and 148.96 ± 4.88kg/mm² in 0.60mm diameter, and maximum elongation was 5.20 ± 0.57% in 0.45mm diameter. 3. Hardness values of experimental group were similar to control groups. Maximum hardness values were 596.2 ± 13.66 Hv in 0.45mm diameter wire of control group I, 590.5 ± 20.08Hv in 0.50 mm diameter wire of control group II, and 563.6 ± 5.35 Hv in 0.70mm diameter wire of experimental group. 4. Torsion properties of experimental group were similar to control group I and more than control group II. Maximum torsion cycles were 31.8 ± 2.48 in 0.45mm diameter of control group I,17.4 ± 4.84 in 0.60mm diameter of control group II, and 24.6 ± 3.04 in 0.45mm diameter of experimental group. 5. Maximum bending cycles of experimental group were smaller than control groups. Maximum bending cycles were 9.00 ± 0.00 in 0.50mm diameter wire of control group I, 10.0 ± 0.82 in 0.40mm diameter wire of control group II, and 8.0 ± 1.26 in 0.50 mm diameter wire of experimental group. 6. Microstructures of experimental and control groups co-existed with martensited austenite structure and elongated austenite structure. 7. The direction of wire fracture was propagated parallel to torsion direction typically and there was no probability showing wire fracture at inclusions and surface scratches. 8. The type of wire fracture was brittle fracture at initiation site and ductile fracture at core.

소아 조갑진균증에서 Itraconazole 주기요법의 치료효과

권경술,이재봉,진현우,오창근,장호선,임재영 대한의진균학회 2003 대한의진균학회지 Vol.8 No.4

E-초등학교 어린이의 영구치 맹출시기 및 순서

권정현,최병재,이제호,김성오,손흥규,최형준 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.2

치아 맹출은 나이, 성별, 인종, 시대에 따라 시기 및 순서의 차이가 있으나, 교과서에 인용되어 임상에서 사용되는 영구치 맹출 및 치근 형성에 대한 자료는 1933년 Logan과 Kronfeld가 발표한 것이므로 현재 한국 어린이의 영구치 맹출 경향과 차이가 있을 수 있다. 따라서 이번 연구의 목적은 한국 어린이의 영구치 맹출연령을 구하고, 이를 근거로 맹출순서를 알아보며, 이전 국내외 연구자료와 비교하여 차이를 알아보는 것이다. 이에 1998년부터 2005년까지 연세대학교 치과대학병원 소아치과에 내원하여 구강검진을 시행한 E-초등학교의 어린이 중 만 6세에서 만 12세의 2,619명 (남자 1,307명, 여자 1,312명)의 자료를 수집하여 영구치의 맹출시기 및 순서에 대해 연구 한 바 다음과 같은 결론을 얻었다. 1. 상악의 영구치 맹출시기는 중절치는 남자 만 6.81세, 여자 만 6.73세, 측절치는 남자 만7.78세, 여자 만7.65세, 견치는 남자 만10.48세, 여자 만9.92세, 제1소구치는 남자 만9.76세, 여자 만9.63세, 제2소구치는 남자 만10.66세, 여자 만10.49세, 제1대구치는 남자 만6.39세, 여자 만6.26세, 제2대구치는 남자 만12.13세, 여자 만 12.03세로 나타났다. 2. 하악의 영구치 맹출시기는 중절치는 남녀 모두 정확한 시기의 측정은 불가능하였지만, 만 6.08세 이전에 맹출한다는 것을 추정 할 수 있었고, 측절치는 남자 만6.78세, 여자 만6.65세, 견치는 남자 만9.76세, 여자 만9.05세, 제1소구치는 남자 만9.82세, 여자 만9.59세, 제2소구치는 남자 만10.67세, 여자 만10.52세, 제1대구치는 남자 만6.22세, 여자 만6.12세, 제2대구치는 남자 만11.58세, 여자 만 11.14세로 나타났다. 3. 맹출순서는 상악은 제1대구치, 중절치, 측절치, 제1소구치, 견치, 제2소구치, 제2대구치 순이었고, 하악은 중절치, 제1대구치, 측절치, 견치, 제1소구치, 제2소구치, 제2대구치 순이었다. 4. 모든 영구치에서 남자보다 여자가 빨리 맹출하였으며, 상악은 약 0.19세, 하악은 약 0.29세 먼저 맹출하였다. 5. 남녀 모두 상악은 측절치와 제1소구치 사이, 하악은 측절치와 견치 사이에 휴지기가 있었고, 남자의 휴지기는 상악 1.98년, 하악 2.98년, 여자는 상악 1.98년, 하악 2.40년이었다. The purpose of this study was to present new data on the timing and sequence of permanent teeth emergence and to compare these findings with the results of earlier studies. The dental examinations had been performed to E-elementary school students, who visited the Yonsei University Dental Hospital between 1998 and 2005; 1,307 boys and 1,312 girls with the age ranging from 6 to 12 years old. The followings were concluded. 1. Eruption time of the maxillary permanent teeth is as follows, It was 6.81 years in male and 6.73 years in female for the central incisor, 7.78 years in male and 7.65 years in female for the lateral incisor, 10.48 years in male and 9.92 years in female for the canine, 9.76 years in male and 9.63 years in female for the first premolar, 10.66 years in male and 10.49 years in female for the second premolar, 6.39 years in male and 6.26 years in female for the first permanent molar, and 12.13 years in male and 12.03 years in female for the second permanent molar. 2. Eruption time of the mandibular permanent teeth is as follows. The central incisor could not be determined in this study, but it is assumed to erupt before the age of 6.08. In the mandible, eruption time was 6.78 years in male and 6.65 years in female for the lateral incisor, 9.76 years in male and 9.05 years in female for the canine, 9.82 years in male and 9.59 years in female for the first premolar, 10.67 years in male and 10.52 years in female for the second premolar, 6.22 years in male and 6.12 years in female for the first permanent molar, and 11.58 years in male and 11.14 years in female for the second permanent molar. 3. The eruption sequence is as follows. In the maxilla, the first permanent molar erupted first, followed by the central incisor, the lateral incisor, the first premolar, the canine, the second premolar, and the second permanent molar. In the mandible, the central incisor erupted first, followed by the first permanent molar, the lateral incisor, the canine, the first premolar, the second premolar, and the second permanent molar. 4. Tooth eruption occurred earlier in female compared to male by average of 0.19 year in the maxilla and 0.29 year in the mandible. 5. In both male and female, the hiatus (interval of rest) occurred between the emergence of lateral incisor and first premolar in the maxilla while it was observed between the lateral incisor and canine in the mandible. Male had a hiatus of 1.98 years in the maxilla and 2.90 years in the mandible, while the female's were 1.98 years and 2.40 years, respectively.

산청군 산림지가 형성요인에 관한 연구

권철현,이상태,신현철,최재채,정영관 경상대학교 농업생명과학연구원 2003 농업생명과학연구 Vol.37 No.1

본 연구는 산청군 남부와 북부지역 361개소의 공시지가와 일반시가에 대하여 분석하였다. 지가 형성요인에 대하여 단계별 회귀분석을 실시하였으며, 그 결과는 다음과 같다. 남부지역에 대한 공시지가와 관련된 5변수 모형에 의한 추정식은 Y = 332.1973 +0.0099X_26 - 0.3577 X_8+ 0.0291X_24 - 2.6768X_2 - 26.1452X_3 이며, 회귀식에 대한 설명력은 90%로 높게 나타났으며, 일반시가에 대한 추정식은 Y = 1035.7976 -185.8280X_21 -3.3937X_1 + 405.6658X_19 -0.4703X_8 이며, 추정식에 대한 설명력은 92%롤 비교적 높게 나타났다. 북부지역에 대한 지가 형성요인에 의한 공시지가 추정모형은 Y = 176.7875 + 0.0205X_25 -0.1168X_8 + 0.0015X_26 -46.3447X_21 로 추정되었으며, 회귀식에 대한 설명력은 96%, 일반시가의 추정 모형은 Y = 203.0697 + 0.0430X_25 + 0.0027X_26 -28.8276X_4 -46.7856X_21 -0.0007X_23 으로 추정되었으며, 회귀식에 대한 설명력은 90%로 나타났다. 이상과 같이 접근요인은 부의 영향을, 그 외 다른 요인들은 지가에 양의 영향을 미치는 것으로 나타났다. This study was carried out to analyze the publicly announced land price and actual land price compared to the northern and southern region of 361 forest land place in Sanchung county. To decipher factors for making forest land price it used the stepwise regression analysis. And the result of analysis are followings; Y = 332.1973 +0.0099X_26 - 0.3577 X_8+ 0.0291X_24 - 2.6768X_2 - 26.1452X_3 (R^2=90%) and the estimation equation of actual price analyze the publicly announced and actual price compared to the northern and southern regions of Sanchung county of price was obtained as Y = 1035.7976 -185.8280X_21 -3.3937X_1 + 405.6658X_19 -0.4703X_8(R^2=92%). In the northern region, the estimation equation of publicly announced land price by the factors for making forest land price was obtained Y = 176.7875 + 0.0205X_25 -0.1168X_8 + 0.0015X_26 -46.3447X_21(R^2=96%) and the estimation equation of actual price was obtained as Y = 203.0697 + 0.0430X_25 + 0.0027X_26 -28.8276X_4 -46.7856X_21 -0.0007X_23(R^2=90%). In the result of the stepwise regression analysis, it was a showed negative effect of the proximity factor and the positive effect between others factor and land price.

이동 단말기용 내장형 slot 안테나 구현

권원현,허재헌 안양대학교 산업기술연구소 2002 自然科學硏究 Vol.9 No.-

본 논문에서는 이동통신 단말기용 내장형 안테나를 연구 개발하였다. 개발된 안테나는 동축형 구조를 갖고 있으며, 스트립 선로를 이용하여 급전 구조를 구현하였다. 안테나의 공진부는 슬롯 구조를 갖는 동축 슬롯 공진형으로 설계하여 IMT-2000 대역인 2.0 GHz 대역에서 공진이 가능하도록 하였다. 구현된 안테나는 26 x 13 x 1.2 ㎣의 크기를 지녀 이동통신 단말기에 쉽게 내장할 수 있음을 알 수 있었다. In this paper, embedded antenna for wireless mobile phone is developed. Developed antenna uses the coaxial type slot structure and its feeding line is implemented by using microstrip line. Resonator part of slot antenna is designed utilizing coaxial type slot resonator structure, and its design parameters are optimized to have 2.0 GHz resonance frequency for IMT-2000 handset. Implemented antenna has 26 x 13 x 1.2 ㎣ physical dimensions, which can be easily applicable to an embedded antenna of mobile phone.

치성낭종으로부터 유래된 편평상피세포암종 : Report of a Case & Review of Literatures

권혁진,현재훈,박형국,김용각 大韓顎顔面成形再建外科學會 1997 Maxillofacial Plastic Reconstructive Surgery Vol.19 No.2

Odontogenic cysts are relatively common pathologic lesions found in the oral and perioral structures, but the case of squamous cell carcinoma arising from those cysts are very uncommon. After first reported of that case in 1889 by Herman, Schwimmer collected 56 cases of previously reported squamous cell carcinoma arising in residual odontogenic cyst during about past one century. More than 60% of cases of carcinoma developing in odontogenic cysts arising in inflammatory periapical or residual cyst, and these tumors are usually well-differentiated with relatively good prognosis, and often are diagnosed as benign lesion in radiographic or clinical examination, therefore definitive diagnosis must be made by histologic examintation. We report a case and review the literatures, in our case, 78-year old woman were clinically and radiographically diagnosed as residual odontogenic cyst. But in histologic examination after enucleation of lesion, mass of squamous cell carinoma were observed, but in other area, typical cyst wall and lining epithelium were observed. And in some area, carcinoma in situ and invading squamous cell carcinoma into the lining epithlium were also observed.

부정교합 아동의 성장에 따른 연조직 측모의 변화

권오원,경희문,장병천,성재현,김정민 대한치과교정학회 1989 대한치과교정학회지 Vol.19 No.3

This investigation was undertaken to know how soft tissue facial profile could changed with age. The 3 serial lateral cephalometric roentgenograms of the twenty nine boys and twenty six girls between 9 and 13 years of age were studied and the findings seemed to warrant the following conclusions. 1. The author made the tables of means, standard deviations in each item, sex, age. 2. Soft tissue facial angle, soft tissue facial convexity including the nose tended to increase, but others tended to remain relatively stable. 3. Facial soft tissue thickness increased with age and the growth of facial soft tissue in the middle rgion (point A, LS, LI)was greater than others in the facial region. 4. In the soft tissue vertical proportions, GI'-Sn/Sn-Me' was 1.1, Sn-St/St-Me' was 0.51:1, Sn-LI/LI-Me' was 0.82.1 and those were stable with age.

mRNA의 3' end processing에 대한 mRNA 중합요소 인산화의 영향

권대환,박재현,송영하,안성훈 한양대학교 이학기술연구소 2006 이학기술논문지 Vol.9 No.-

RNA 중합효소의 C-terminal은 YSPTSPS의 반복적인 아미노산 서열을 갖고 있으며, 이들의 인산화는 전사의 개시, 중합, 또는 종결단계에 중요하다고 알려져 있다. 본 연구에서는 이러한 RNA 중합효소의 인산화가 mRNA의 3' end processing에 미치는 영향을 조사하였다. C-terminal domain (CTD) of RNA polymerase Ⅱ contains a repeated heptameric sequence (YSPTSPS) which is phosphorylated at serine 2 and 5. Phosphorylation of CTD in elongating RNA polymerase Ⅱ has been suggested to play a role in transcriptional initiation, elongation or termination. In the present study, we investigated the effect of RNA polymerase Ⅱ CTD phosphorylation on the 3' end processing of mRNA.

말초혈액에서 Tg mRNA에 대한 역전사 중합효소 연쇄 반응법의 갑상선 재발암의 분자생물학적 진단

권성일,박기룡,김현영,신채희,임영찬,최영식,박요한,이강대,장희경,이재화,염하용 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.4

연구배경: 갑상선암은 다른 조직에 발생한 암에 비해 비교적 천천히 자라므로 대부분 예후가 양호하지만, 일부에서는 주위 조직으로 침윤하거나 혹은 원격 전이로 인하여 치명적인 결과를 초래할 수 있다. 갑상선전절제술 및 131^I 제거술 후 경과 관찰시 갑상선암의 재발과 전이의 진단에 있어 131^I 스캔과 혈청 Tg의 측정이 현재 임상에서 가장 많이 이용되고 있으나 이 방법에는 여러 가지의 결점이 있다. 최근 Tg mRNA에 대한 RT-PCR법을 이용한 여러 연구결과는 131^I 스캔과 혈청 Tg 측정의 결점을 보완할 수 있는 좋은 보조적인 진단법으로 이용할 수 있을 가능성을 제시하였다. 이에 말초혈액에서 측정한 Tg mRNA에 대한 RT-PCR법이 갑상선 절제술 및 방사성요드 치료 후 갑상선암의 재발 및 전이 유무의 진단에 유용한가를 알아보고자 이 연구 시행하였다. 방법: 분화된 갑상선암으로 진단된 후 갑상선전절제술을 시행받고 방사성요드 치료를 받은 환자 중 현재까지 한차례에 이상 추적 방사성요드 전신 스캔을 시행하고 추적관찰이 가능했던 유두선암 35예, 여포선암 5예를 대상으로 연구를 시행하였다. 대상군은 131^I 스캔 소견상 음성인 군(Group Ⅰ), 잔여조직이 있는 군(Group Ⅱ), 국소전이가 있는 군(Group Ⅲ), 및 원격전이 군(Group Ⅳ)으로 구분하였다. 정상 대조군은 갑상선질환이 없는 10예의 건강인으로 하였다. 대상환자의 말초혈액을 이용한 Tg mRNA에 대해 특이적인 primer를 이용하여 RT-PCR 및 nested RT-PCR을 시행하였다. 결과: 본 연구 결과는 다음과 같다. 1) 131^I 스캔 소견상 음성인 군 21예 중 1예에서 Tg가 양성소견을 보였다. Anti Tg Ab가 양성인 4예 모두 Tg가 음성을 보였다. 잔여조직이 있거나 국소전이 및 원격전이를 보인 군 19예 중 Tg가 양성인 경우는 4예였으나, Tg mRNA는 전예에서 양성이었다. 2) 131^I 스캔에서 국소 및 원격전이 소견을 보인 8예 중 4예에서 Tg가 음성으로 131^I 스캔과 혈청 Tg 사이에 불일치 소견을 보였다. 3) 말초혈액에서 특이적인 primer를 이용하여 RT-PCR 및 nested RT-PCR을 시행한 결과 대상군 40예 및 정상 대조군 10예 모두에서 Tg mRNA가 양성을 보였다. 결론: 본 연구에서 갑상선 절제술 및 방사성요드 치료 후 갑상선암의 재발 및 전이 유무를 평가함에 있어 역전사 중합효소 연쇄 반응법을 이용한 Tg mRNA 측정의 의의는 재평가되어야 한다고 생각된다. Background: Differentiated thyroid cancer is the most common endocrine malignancy. Despite advances in the treatment of thyroid cancer, disease recurrence and metastasis may occur in as many as 20% of patients, and so continues to pose major problems in its clinical management. Serum thyroglobulin (Tg) measurements, by immunoassay, are used to detect residual or recurrent thyroid cancer following thyriod ablation. However, the usefulness of immunoassay is limited by both the requirement for thyroid hormone withdrawal, to attain optimal test sensitivity, and interference by the antithyroglobulin antibody (Anti-Tg Ab). Recent studies have reported the clinical usefulness of reverse transcription-polymerase chain reaction (RT-PCR) detection of Tg mRNA in the peripheral blood of patients with differentiated thyroid carcinomas. We performed this study to evaluated the usefulness RT-PCR of Tg mRNA in peripheral blood of patients with thyroid carcinoma following a total thyroidectomy and radioiodine ablation therapy. Methods: Forty cases that underwent a total thyroidectomy and radioiodine ablation therapy were included in this study. Of the 40 patients, 35 were papillary carcinomas and 5 were follicular carcinomas. Ten normal control subjects were also studied. Tg mRNA was extracted. Then RT-PCR and nested RT-PCR, were run with specific Tg primers. Concurrently, DNA sequencing of the isolates was carried out to prove the isolates were identical to the nucleotide sequence of the Tg. Results: The Tg was detected in 4 of 19 patients, with either a residual thyroid bed, or metastasis, on a 131^I whole body scan and in 1 of 21 patients with a negative radioiodine scan. Surprisingly, the Tg mRNA was detected in all the patients and normal controls. Conclusion: From our results we can not recommend Tg mRNA, detected by RT-PCR in peripheral blood, as a tumor marker superior to that of the Tg serum level. We consider an intensive re-evaluation of the method is required before considering its clinical applications (J Kor Soc Endocrinol 17:501∼513, 2002).