한약수치에 관한 연구(제 8보) : 오수유 탕포법 The Changes of Physico-chemical Parameter and Biological Activities by Processing of Evodia Fruit

박성환,이우정,최혁재,송보완,김동현,김남재 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

We have studied the physico-chemical change and pharmacological transformation of traditional herbal medicines with processing. Evodia fruit (EF) has processed for the purpose of detoxification and reduction of its bitter taste. There are various methods of processing EF in Oriental medicinal references. Among them, we processed EF according to the method of Sang-han theory, the most famous medicinal reference. We processed EF with washing in hot water, and then dried. Processed EFs(PEFs) were prepared according to the above procedure through repetition of 1,3,5 and 7 times respectively. The contents of weight loss, water extract, diluted ethanol extract, ether extract, total ash, acid insoluble ash, alkaloids and limonin in non-processed EF (NPEF) and PEFs were examined. The weight loss, and contents of water extract and dilute ethanol extract in PEF showed decrease in proportion to increase of washing time, while the contents of ether extract, total ash and acid insoluble ash showed little change as compared with those of NPEF. And the content of evodiamine and rutaecarpine was not changed distinctly. However, the content of limonin decreased in the final processed material in proportion to increase of washing times with hot water. And the intense of bitter taste in PEF was also reduced. These results were ascribed to the flowing-out of the water-soluble portion. The biological activities of NPEF and PEF were also investigated. In the test of DPPH scavenging effect, xanthine oxidase inhibition effect and TBA-Rs effect, PEF was more effective than NPEF in vitro. Also, both NPEF and PEF showed potent analgesic and anti-inflammatory effects against in mice. Especially, PEF by 3 times washing with hot water was more effective than other PEFs. From these results, it is considered that PEF should be prepared by 3 times washing with hot water.

MIC구형 공진기를 이용한 주파수 스캐닝 안테나

박한규,최평석,양혁재 연세대학교 산업기술연구소 1980 논문집 Vol.12 No.2

마이크로스트립 單一共振器를 直列로 연결한 周波數스캐닝 안테나의 製作 및 動作原理에 대하여 고찰하였다. 마이크로스프립 基板의 두께가 1/32inch(0.8mm)이고 比誘電率 εr=2.45를 사용하였을 경우 8.7㎓에서 9.25㎓까지 周波數를 변환시켰을 때 ±30°로 스캐닝 하였으며 이때 共振器 자체의 反射波에 의한 位相偏移가 30%까지 차지하였다. In this paper, the principles and fabrication of the frequency scanning antenna formed by the cascaded array of single resonators are described. As the microstrip substrate, the depth of 1/32 inch and ?? of 2.45 substrate is used and the resultant beam scan angle is 30° from 8.7 ㎓ to 9.25 ㎓ range. It is showed that this scanning is due to the phase shift in a resonator as well as the transmission line and the resonator phase shift responsible for 30% of the total phase shift. Experimental results shows a little discrepancy from the theoretical value and this considered to come from the mis-matching of each resonators.

기업의 교육·훈련 투자 실적과 성과요인과의 관련성 연구

박계홍,권혁수 한국중소기업학회 2002 中小企業硏究 Vol.24 No.3

교육·훈련 투자비와 기업성과요인들과의 관련성을 연구하기 위하여 2000년 말 현재 우리나라 제조업 500여개 업체를 대상으로 우편조사를 실시하여 분석이 가능한 49개 업체를 중심으로 분석하였다. 교육·훈련 투자비와 성과요인들과의 관련성에 대한 기존 연구의 검토와 이론정리를 통해 가설을 설정하고, 실증분석을 실시하였다. 교육·훈련 투자비를 종속변수로 한, 비용함수를 추정하여 교육·훈련 투자가 생산성에 어느 정도 영향을 주고 기업의 고용안정성에도 어느 정도 기여하는지 조명하였다. TheAn Empirical study on the relationship of the important factors determining the performance of organization(employment separation rate, average monthly real wage, labour productivity) as they have influenced on the existence, growth and the development of an organization. Therefore, this study was conducted to provide suggestion for a future research by establishing the most important factors determining the success of organization relations among in terms of factors affecting the efficiency of Cost Education Vocational Training they provide centering on the influence caused by such factors. On the basis of this theoretical observation we established models and hypotheses of research. We carried out at the same time positive analysis with a survey by questionnaire in order to verify the research hypotheses(Manufacturing 49 unit). We proceeded to the survey by questionnaire after confirming relevancy of the research model in preliminary examination. We performed statical disposition and analysis of the samples based on this. Before verifying the research hypotheses We conducted analysis of factors to secure the soundness and reliability of measuring tools. Then, We carried out descriptive statistical analysis of the distribution and statistical amount of the variables used in this study. Finally, We utilized such statistical analysis as multiple regression analysis, parameter regression analysis and process analysis.

운동이 비만 여성의 심근산소소비량과 심전도 QTc 간격에 미치는 영향

이혁종,박윤정,김용권,한구석,진영수 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1

The purpose of this study was to investigate the effects of exercise staining on MVO_2 and electrocardiogram QTc interval in obese woman and to propose the desirable method for weight loss. Subjects were fifteen obese women for this study. 8 subjects were prolonged QTc interval group and 7 subjects were normal QTc interval. They participated in exercise program consisted of aerobic exercise and weight training exercise at A Medical Center. The body composition including Boyd Weight, BMI, WHR and % Body Fat was measured. The resting and exercise(Bruce protocol 7th min) rate-pressure product(RPP) could be measured with HR and systolic BP for MVO_2 measurement. The electrocardiogram QTc interval was calculated with Bazzett's formula using automated software program. The measured data of this study were as follows: 1) After participating the exercise program consisted of aerobic exercise and weight training exercise, Body Weight, BMI, WHR and % Body Fat were significantly changed in two groups. (p<.05). 2. After participating in the exercise program consisted of aerobic exercise and weight training exercise, the resting and exercise MVO_2 using RPP were significantly changed in two groups(p<.05). 3) After participating in the exercise program consisted of aerobic exercise and weight training exercise, the electrocardiogram QTc interval were decreased but were not significantly changed in prolonged QTc interval group. (p<.29). However, it was significantly decreased in prolonged QTc interval(p<.00).

관상동맥 스텐트 내 재협착의 발생에 미치는 임상적 관동맥 조영술적 요인들

윤혁준,김기식,박형섭,이영수,현대우,한성욱,허승호,김윤년,김권배,박남희,원경숙 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.12

한약수치에 관한 연구(제 9보) : 炒甘草 제법의 표준화 및 규격화(1) Preparing Standardization and Regulation of Stir-Frying Glycyrrhzia root(1)

최혁재,이우정,박성환,송보완,김동현,김남재 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

In this study, We carried out the preparing standardization and regulation of processed Glycyrrhizae Radix(PGR) which have been widely used in oriental medicines. Glycyrrhizae Radix(GR) have been generally prepared by the stir-frying, or mix-frying with honey for purpose of decreasing sweetness and augmenting vitality. Firstly, we tried to standardize PGR prepared by the stir-frying. We purchased 14 kinds of PGR and non-processed GR(NPGR) at oriental physician's offices and oriental pharmacies on a nation scale, respectively. The amounts of dry on loss, water extract, diluted ethanol extract, ether extract, total ash, acid insoluble ash, glycyrrhizin(GL), glycyrrhetic acid(GA) and liquiritin(LQ) of them were examined. The amounts of dray on loss, GL and LQ in commercial PGRs showed remarkable decrease, while GA showed increase as compared with NPGR. In order to standardize preparing method of PGR, the effect of heating time on physico-chemical parameters and biological activities were examined. Physico-chemical parameters such as dry on loss, extract amount, GL and LQ contents in PGRs showed decrease, however, GA was increased with heating time as compared with NPGR. Also, GA obtained form heat-treated GR, was found as an artifact in PGRs. PGR was more effective than NPGR in vitro test of DPPH scavenging effect and TBA-Rs reducing effect. PGR and NPGR showed potent hepatoprotective effect on CCl_(1)-intoxicated rats. Especially, PGR prepared by 80 min of heating was the most effective. Considering these results, the optimal condition for PGR preparation was 150℃ for 80min.

교통사고 발생 추이에 관한 연구

양혁준,최봉근,윤태영,최중명,박순영,유동준 慶熙大學校 醫科大學 1997 慶熙 醫大 論文集 Vol.22 No.1

경고막적 및 고막외적 전극위치에 따른 와우전위의 비교연구

장동임,박철규,이병돈,장혁순,강주원 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

Electrocochleography is a method of the measurement of electrical events generated either within the cochlea or by primary afferent neurons. It includes measures of summating potential(SP) and cochlear microphonics(CM) from the cochlea, and action potential(AC) from the auditory nerve. There are severval diffefent ways to measure the potentials, mainly transtympanic and extratympanic methods. The purpose of this study is to provide a normal data of eletrocochleography in adults and compare the results obtained by extratympanic and transtympanic methods. The following results were obstained: 1. As the intensity of sound was increased, the SP amplitude and AP amplitude were increased. There was no significant difference between extratympanic and transtympanic method. 2. As the intensity of sound was increased, the SP latency and AP latency were shortened without significant difference between two different methods. 3. As the intensity of sound was increased, the SP/AP ratio was increased without difference in both methods which was less than o.30. 4. Non-invasive method of electrocohleography, the extratympanic method, can be one of the easy method an can be used widely clinically.

기관에서 발생한 전이성 갑상선 유두상 암종 1례

장선호,박철규,이병돈,장혁순,강주원 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.2

Papillary adenocarcionma has been common malignant tumor of human thyroid gland, and metastasize to the lung and bone as well. But endotracheal meastasis of papillary adenocarcinoma is very unusual. A 75 years old woman was presented with a metastatic papillary thyroid adeno- carcinoma in the trachea, 10 years after total thyroidectomy. The tumor mass was located in the anterior wall of tracheal lumen. The mass was confirmed with pathologic finding. We describe a case of tracheal papillary adenocarinoma of thyroid gland origin and discuss the current recommendation for management.

중이강 내에 발생한 선천성진주종

김광수,박철규,이병돈,장혁순,강주원 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.2

Congenital cholesteatoma is a rare disease which originated from the ectoderm that from the primitive notochord and embryonal cell rests. It may occur in any portion of the cranial bones. Various symptoms may develope about position of the lesions. If the lesion located in the middle ear, symptoms were showed conductive hearing loss and normal tympanic membrane. We have experienced two cases of congenital cholesteatomas which were located in the middle ear. We report these cases with review of literatures.