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      • 유방암과 섬유선종의 방사선학적 소견 : 유방 단순촬영술과 유방 초음파검사 소견의 비교 연구 Studies on mammographic and ultrasonographic findings evaluation

        임한혁,최득린,고은석,이혜경,임철완,이상진,홍현숙,최교창,김영화,박재성 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

        Purpose : To evaluate the utility of mammography and ultrasonography in study of morphologic differential diagnosis between malignant and benign mass. Materials and Methods : Average age of patients with breast cancer was 48.4 year-old, and that of fibroadenoma was 29.4 year-old. The equipments used for examination were MF-159 high frequency mammography(Bennet Co.) and Acoustic image 5200S. We evaluated mammographic findings about breast parenchymal pattern, calcification, margin and size of the mass associated tumor nature, and ultrasonographic findings about shape, height and width, internal homogenicity and echo pattern, wall contour, boundary echo, and posterior shadow in breast mass. Thirty-seven of mammographic findings and 34 cases of ultrasonogreaphic findings in pathologically proven breast cancer and 34 case of mammographic findings and 71 cases of ultrasonographic findings in breast fibroadenoma were reviewed retrospectively. Results : In mammographic study, the parenchymal patterns of breast cancer according to Wolfe classification were NI(16.2%), PI(24.3%), P@(37.8%), and DY(21.6%) and those in fibroadenoma were NI(3.1%), Pl(11.7%), P2(35.2%),and DY(50%). Mammographic findings about presence of calcification were as follows; only calcification(16.2%), only mass(51.3%), and mass with calcification(32.5%) in breast cancer, and only mass(91.2%), mass with calcification(8.8%) in fibroadenoma. The features of mass margins were classified as ill-defined margin(45.9%), well-defined(5.4%), and well-defined with partial spiculation(48.6%) in breast cancer and ill-defined(20.5%), well-defined(73.5%), and well-defined with partial spiculation(5.8%) in fibroadenoma. The mass were grouped by size; 1-2cm(37.8%), 2-4cm(45.9%), and 4-6cm(16.3%) in breast cancer and 1-2cm(79.4%), 2-4cm(17.6%), and 4-6cm (3.0%) in fibroadenoma. On ultrasonographic study, the shape of masses in breast cancer were lobulated(82.3%),oval(14.7%), and round(3.0%),and those in fibroadenoma were lobulated(14.0%), oval(57.7%), and round(18.3%). The cases that the height was longer than width were 32.3% in breast cancer and 0% in fibroadenoma. The findings about homogenecity and echo patterns were as follows; hypoechoic(52.9%) and mixed(47.1%) in breast cancer and hypoechoic(2.8%), hypoechoic(63.4%), and mixed(33.8%) in fibroadenoma. The margin of masses were smooth in 85.9% of fibroadenoma, and irregular in 73.6% of breast cancer. The boundary echoes of masses and decreased posterior echo shadow were seen only in 61.8% and 55.9% of breast cancer, respectively. Conclusion: The margin and calcifications are more clearly delineated on mammography but breast cancer and fibroadenoma, both are more commonly developed in dense parenchymal pattern(P2+DY),and there findings are easily obscured in mammography. So ultrasoography is very useful in these masses evaluation, especially amoung young patients.

      • KCI등재

        광중합형 글라스 아이오노머 시멘트의 개발에 관한 연구

        김철위,윤수한,임범순 대한치과기재학회 1998 대한치과재료학회지 Vol.25 No.1

        The object of this study was to synthesize the experimental light-activated glass ionomer cement change of glass components such as aluminum, fluorine, calcium, and strontium. To reinforce the glass ionomer cement, additions of metallic powder, ceramic powder, and light-activated composite resin to glass ionomer cements were performed. Radiopacity, comprehensive strength, bond strength, fracture toughness, sloubility, and cytotoxicity of the various experimental glass ionomer cements were investigated. From the experiment, the following results were obtained: 1. Experimental light-activated glass ionomer cement showed similar physical and mechanical properties to commercial glass ionomer cement. Radiopacity, resistance of solubility, fracture thoughness, and compressive strength of the experimental cement were superior to those of commercial cements, but bond strength and biocompatibility of the experimental cement were inferior to commercial cements. 2. Addition of amalgam powder to light-activated glass ionomer cement resulted in the lower compressive strength and fracture toughness, but addition of aluminium powder resulted in the enhanced the fracture toughness. 3. Addition of alumina powder (Al₂O₃) could enhance the compressive strength and fracture toughness of the glass ionomer cement without sacrificing of the esthetic property. 4. Physical mixing light-activated glass ionomer cement with light-activated composite resin could enhanced the physical properties except for bond strength.

      • SD Rats를 이용 1-hexene의 흡입독성 연구

        김현영,임철홍,정용현,이권섭,이성배,이준연,한정희,전윤석,이용묵 한국환경독성학회 2001 환경독성보건학회지 Vol.16 No.4

        The purpose of this study was to investigate the acute (4 hours) and repeated-dose (6 hours a day, 5 days a week, 4 weeks) toxic effects of I -hexene on Sprague- Dawley (SD) rats which were treated by inhalation. The results were as follows; I. The median lethal concentration (LC_(50)) was estimated 52,694 ppm (confidence limit 95%; 49,494~55,447 ppm) in acute inhalation. Abnormal clinical signs related to the l-Hexene were not observed with the acute inhalation dose. Gross findings of necropsy revealed on evidence of specific toxicity related to the 1-hexene, II. By repeated inhalation exposure the body weight of male were more or less reduced by the dose of 2,500 ppm and 5,000 ppm compared with control group. However there were no significant variation hematology and blood biochemistry for the exposed rats compared with the control rats. Abnormal clinical signs and gross findings of necropsy related to the 1-hexene were not shown. In conclusion when we exposed I-hexene to SD rats for 4 weeks, 5 days per week, 6 hours per day, the Lowest observed effect level (LOEL) was over 2,500 ppm and Non observed effect level (NOEL) was below 500 ppm.

      • S.D. Rats를 이용 1, 1-Dichloro-1-fluoroethane의 아민성 흡입독성 연구

        김현영,이성배,임철홍,김철우,점용현,한정희,전윤석,최수영,강대봉,이용묵 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.1

        There were no specific effects for test materials on Sprague-Dawley (S.D.) rats in clinical symptoms, amounts of food intakes, weight changes, laboratory findings, and pathology after whole body l, l-Dichloro-1 -fluoroethane (used as coolant, metal cleaner and solvents) exposure(0, 1,500, 3,000, and 6,000 ppm) for 13 weeks (6 hour/day, 5 days/week). However, the loss of capillary vessels in eyeball (pupil) was observed in a female rat among 6,000 ppm group. Though there was a tendency for MCHC (Mean Corpuscular Hemoglobin Concentration) in rat to be decreased (p<0.05), it was not regarded as abnormal because the values were within normal limits. In asthma-stimulation related evaluations, there was also a tendency for inflammatory cell counts in bronchoalveolar lavages to be increased. But it had no statistical significance, and also no dependency on sex and the exposed concentration. Based on this result, the non observed effect level (NOEL) induced by 1, 1-Dichloro-l -fluoroethene inhalation was evaluated in groups with 3,000 ppm below (S .D. Rats, 13 weeks). Finally, it was concluded that the short term exposal of 1, 1-Dichloro-l-fluoroethane is not considered as a asthma stimulant by inhalation despite of some study limitations such as test animals use and short-term exposure .

      • KCI등재

        크롬(Ⅵ)의 체내 흡수와 소실속도에 관한 연구

        김현영,이성배,임철홍,이권섭,정용현,이종성,한정희,전윤석,황호순,이용묵 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.1

        The CrO3 mostly used in plating. metal surface disposal, leather, cosmetic manufacturing, as an experiment material by repeatedly inhaling and exposure the male S.D. rats at a 0.00, 0.2., 0.50, 1.25 mg/㎡ concentration(particle size: 0.5-0.5 aerosol)6hours a day, 5day a week in 13weeks comparing with 2weeks, 8weeks of recovery group about the noxiousness of the experiment animal and the reduce scale of the CrO3 in the internal organ especially in blook and respiratory organ with the period of convalescent and clearance. The experiment results which we received are as follows. 1. In blood the RBC, HGB and HCT experiment, rats with 0.20, 0.50 mg/㎡ concentration showed that there were some decreases but not dependent. The kidneys absolute weight compared with control group was reduced intentionally(p〈0.05) and the lungs absolute weight compared with control group showed intentional increase(p〉0.05). 2. After the exposure of the experiment material, the whole blook, l\blood plasma and red blood cell in blood by (x): the period of convalescent, per (y); the decreasing of Cr concentration, was y=66.51 e -0.057x, y=67.2 e-0.101x, y=70.01 e-0.030 in 0.50 mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life (day)was estimated 12.0, 6086, 23.0 each. 3, After the exposure of the experiment material, the experiment animals lung, liver and kidneys by(x); the period of convalescent, per (y); the decreasing of Cr conentration, was y=1808 e-0.00493x, y=12.02e-0.0297x, y=67.61 e-0.0292x in 0.50mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life(day)was estimated 140.6, 23.3, 23.7, each, and including lung, liver with all of the experiment internal organs, the Cr clearance decreased as the exposure concentration increased.

      • Aortocaval Fistula by Luetic Abdominal Aortic Aneurysm : Report of a case

        Lim, Sang Hyun,Lee, Cheol Joo,Roh,Hwan-Kyu,Kim, Dae Jun,Han, Jung Sun,Shin, Joon Han,Kim, Han Soo 아주대학교 1996 아주의학 Vol.1 No.2

        A 53-year-old male patient was operated on because of a spontaneous abdominal aortic aneurysm with aortocaval fistula. The fistula was successfully closed and bifurcated woven Dacron graft was used to replace the aneurysm. The patient had with characteristic signs and symptoms of aortic aneurysm with arteriovenous fistula. Proper diagnosis and prompt surgical repair of aortocaval fistula saved the patient. The use of rapid infusion system provided stable hemodynamics during the operation.

      • Optical Effect of Surface Morphology of Ag on Multilayer Electrode Applications for OLEDs

        Yun Cheol Han,Myung Sub Lim,Jun Hong Park,Kyung Cheol Choi IEEE 2014 IEEE electron device letters Vol.35 No.2

        <P>We investigated the optical properties of a dielectric-metal-dielectric (DMD) electrode in relation to the surface morphology of Ag. We intentionally modified the number of voids and the surface coverage of the Ag layer. Normal and oblique incident configurations for transmittance measurement were employed to establish the relations between the Ag morphology and optical transmittance of the DMD electrode. For the configuration of MoO3/Ag/MoO3 (MAM), variation in the surface morphology of the Ag minimized the light scattering loss and the absorption of photons. This could lead to 18.6% enhancement of the transmittance at λ = 550 nm. The optical out-coupling was also enhanced in OLEDs, which was based on the MAM anode incorporating the continuous Ag film.</P>

      • 개량형 Durometer의 경도치를 이용한 건조 시멘트 모르타르의 마감시기가 압축강도에 미치는 영향

        한수환 ( Han Soo-hwan ),임군수 ( Lim Gun-su ),김종 ( Kim Jong ),한민철 ( Han Min-cheol ),한천구 ( Han Cheon-goo ) 한국구조물진단유지관리공학회 2021 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.25 No.1

        본 연구는 개량형 Durometer를 이용하여 DM의 초결이전부터 종결사이 경도치에 따라 1회 미장을 실시하여 미장시기에 따른 압축강도 변화를 고찰하고자 하였다. 실험결과 압축강도는 60∼70 HD에서 미장을 실시할 경우 여타의 미장시기보다 높게 나타났다. 하지만, 미장을 70 HD에서 실시할 경우, DM의 표면부가 종결시간에 가까워 미장 시공성이 떨어지는 것으로 확인되었다. 따라서, 압축강도 및 시공성 측면에서 60 HD 시기에 미장시공을 실시하는 것이 가장 바람직한 것으로 분석되었다.

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