난지형 조숙종 마늘 신품종 ‘올캐’ 특성

최학순(Hak Soon Choi1),채원병(Won-Byoung Chae),곽용범(Yong-Bum Kwack),정명일(Myeong-Il Jeong) 한국원예학회 2008 한국원예학회 학술발표요지 Vol.2008 No.12

원예연구소 남해출장소에서는 원예적 특성이 우수한 유전자원을 도입 선발하여 ‘올캐’로 명명하였다. 특성평가를 2000년부터 3년간 실시하였으며 2003년부터 3년간 지역적응시험을 실시한 결과 그 특성이 우수하여 품종등록 하였다. 도입 육성한 ‘올캐’ 마늘은 난지형 조숙종 마늘로 생태형으로는 난지형이며 추대형은 완전 추대종이다. 인경의 모양은 아래가 평편한 구형이며 구색과 인편색은 약간 자색이 돈다. 인편의 배열은 동심형(concentric)으로 ‘남도’ 마늘과 같다. 초형은 직립이며 초장, 엽초경 및 잎의 수는 대비종인 ‘남도’ 마늘에 비해서 약간 작거나 적으며 잎의 색깔은 ‘남도’ 마늘에 비해서 약간 연한 녹색이다. 평균구중은 42.2g으로 ‘남도’ 마늘 40.5g 보다 약간 무거우며 인경의 모양은 대비종인 ‘남도’ 마늘과 비슷하다. ‘올캐’ 마늘의 추대기는 3월 하순으로 ‘남도’ 마늘보다 15~20일 정도 빠르며 수확기도 일주일 이상 빠르다. Namhae Sub-station of National Horticultural Research Institute has collected 240 different garlic germplasms since 1999 and has used germplasms of superior quality. Among them, ‘Namhae 57328’ is a precocious variety with superior characteristics of growth and bulb, and was named ‘Allkae’ garlic (Allium sativum) in 2006. The garlic was registered after 3 consecutive years’ assessment of the variety trait starting from 2000 and a 3 consecutive years’ adaptability test from 2003. The ecotype of ‘Allkae’ garlic is southern one and bolting one is complete bolting type. The bottom of a bulb is flat and the colors of a bulb and a clove are light purple, and the arrangement of cloves is concentric as in ‘Namdo’ garlic. The plant type is erect one and its height is slightly smaller than ‘Namdo’ garlic’ one but it’s bolting in mid March which is about 20 days ahead of ‘Namdo’ garlic. Average bulb weight is 42.2 g which is slightly heavier than ‘Namdo’ garlic (40.5 g). The shape of the bulb is similar with ‘Namdo’ garlic.

새로운 Acetylcholinesterase inhibitors의 합성

최순규,김형민,조승환,최학기,박유미,이용균,정대일,김인식,한정태 동아대학교 부설 기초과학연구소 2004 基礎科學硏究論文集 Vol.21 No.1

노인성 치매의 일종인 alzheimer's disease의 효과적인 억제제를 합성하기 위해 우리는 분자 모델링에 의한 가장 적합한 물질인 m-[(N,N,N-trimethylammonio)phenyl]boronic acid를 합성하였다. 출발물질인 3-aminophenylboronic acid monohydrate의 경우 boronic acid의 작용기인 hydroxyl group을 protecting시킴으로써 반응의 안정성을 기하였다. Quarternary ammonium salt는 과량의 methyliodide와 염기 촉매인 potassium hydrogen carbonate를 사용하여 용매인 methanol에서 반응시켜 상당히 높은 수율을 얻을 수 있었다. 또한 과량의 methyliodide와 염기촉매인 potassium hydrogen carbonate를 사용하여 용매인 methanol에서 반응시킨 결과 boronic acid의 protection없이도 안정하게 반응이 진행되어짐을 확인할 수 있었다. In order to syntheisize a effective inhibotor for alzheimer's disease, we synthesized m-[(N,N,N-trimethylammonio)phenyl]boronic acid 4 which is designed by molecular modeling form. We protected the hydroxyl group of 3-aminophenylboronic acid monohydrate 1 with ethlyne glycol to remove the reactivity if hydroxyl group. To synthesize m-[(N,N,N-trimethylammonio)phenyl]boronic acid 4, we reacted 3-aminophenylboronic acid monohydrate 1 with ezcess methyl iodide and potassium hydrogen carbonate as a base-catalyst in methanol. but On executed reaction without protection on hydroxyl group, we found out the result that the hydroxyl group of boronic acid group at 3-aminophenylboronic acid monohydrate 1 didn't react with excess methyliodide. Synthesized m-[(N,N,N-trimethylammonio)phenyl]boronic acid 4 is in progress about biological tests as a plausible acetylcholinesterase inhibitor.

프레탈^(R)정(실로스타졸 50mg)에 대한 실로졸^(R)정의 생물학적 동등성

최한곤,권기철,이승호,김학미,박병주,유봉규,이종달,이경희,하정희,우종수,박인숙,최진석,용철순 한국병원약사회 2003 병원약사회지 Vol.20 No.1

Bioequivalence of two cilostazol tablets, the Pletaal^(R)(Korea Otsuka Pharmaceutical Co., Ltd.) and the Cilozol^(R)(Hanmi Pharmaceutical Co., Ltd.), was evaluated according to the guideline of KFDA, Sixteen normal male volunteers(age 20~29 years old) were divided into two groups and a randomized 22 cross-over study was employed. After two tablets containing 50㎎ of cilostazol were orally administered. blood was taken at predetermined time intervals and the concentration of cilostazol in plasma was determined with an HPLC method using UV detector. The pharmacokinetic parameters(C_(max), T_(max) and AUC_(t)) were calculated and ANOVA was utilized for the statistical analysis of parameters. The results showed that the differences in C_(max), T_(max) and AUC_(t) between two tablets were 4.99%, 1.74% and 7.68%, respectively. The powers(1-β) for C_(max), T_(max) and AUC_(t) were83.92%, 80.12% and 85.03%, respectively. Detectable differences(Δ) and confidence intervals were all less than 20%, and confidence interval of all the parameters were also less than 20% at the significance level(α) of 0.05. All of these parameters met the criteria of KFDA for bioequivalence, indicating that Cilozol^(R) tablet is bioequivalent to Pletaal^(R) tablet.

임신중 우측난소의 자궁내막장종의 성장과 파열의 1례

이종학,홍순도,남상욱,최종호,허광현,박일영 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.2

계명의대 산부인과에서 35세된 경산부에서 임신과 동반된 우측 난소의 자궁내막낭종의 성장과 파열을 경험하였기에 이에 문헌고찰과 함께 보고하는 바이다 Pregnancy had long been considered to have beneficial effect on endometriosis. During the pregnancy, extrauterine endomertrial tissues did not growth or enlarged because of physiologic amenorrhea and producing hormonal effect. However, we experienced a patient who underwent emergency exploratory laparotmy at gestation week 34/4 for rupture of an ovarian endometriotic cyst. The patient had a Cesarean section delivery of a 1,960gm female baby, who died at 1st day of life.

GG-38 : Minimal invasive surgery (LESS) for huge cystic adnexal tumors in whole abdomen

( In Young Choi ),( Ji Hye Lee ),( Mi Hyun Park ),( Ji Kwoun Park ),( Jeong Kyu Shin1 ),( Won Jun Choi1 ),( Soon Ae Lee ),( Jong Hak Lee ),( Won Young Paik ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

Laparoendoscopic single-site surgery (LESS) is helpful if not an evidence of suspicious malignancy in huge adnexa tumors. This approach might be reasonable alternative to conventional laparoscopic surgery. We report two cases with LESS for huge cystic adnexal tumors in whole abdomen. A 58 years old multigravida woman in menopause underwent removal of a huge cystic adnexal mass that occupied her entire abdomen by LESS.(ca.5200ml aspiration) A 15 years old single nulligravida woman had a huge cystic adnexal tumor in whole abdomen reaching to the level of the xyphoid process. A needle through the transumbilical single port was inserted directly under the mass. Subsequently, 8000 ml of cystic fluid was aspirated without spillage.

연약지반에 시공된 보강토 옹벽의 거동해석에 관한 연구

심태섭,최순범,김선학 朝鮮大學校 建設技術硏究所 2007 建設技術硏究 Vol.27 No.1

It was found that the factor of behavior in the retaining wall of reinforced earth on poor subsoil was influenced by load increment, consolidation time and pore-water pressure. Finite element analysis was conducted by using SAGECRISP program for the behavior analysis of poor subsoil and the retaining wall of reinforced earth in this theory. Firstly, the validity of replacement method was examined for the improvement of excessive displacement of the retaining wall of reinforced earth. Secondly, the influence in the ground behavior of the vertical space of reinforced materials on the back of retaining wall was analyzed. Lastly, the width and the depth of appropriate replacement in appling replacement method were suggested. As the result of this study, following conclusion was got. Replacement method take effect on the behavior improvement of the retaining wall of reinforced earth because the case of replacement method(width: 8m, depth: 5m) in the retaining wall of reinforced earth on poor subsoil shows that improvement effect of vertical displacement is 2 ~ 3cm in the upper direction. 7.5 ~ 26.2cm in the lower direction, 11.6 ~ 26.4cm in the vertical displacement on the back of retaing wall and 7.1 ~ 8.6% in shearing strain. The improvement of horizontal displacement was not great because △h_(h)/H maintained similar value despite the increase of replacement width.

재접합술의 일차 보고

나수균,윤치순,최창욱,김학현 순천향의과대학 1979 Journal of Soonchunhyang Medical Science Vol.2 No.4

It was about 70 years ago that Carrel and Guthrie started experimental limb replantation. Malt succeeded, firstly, replantation of the amputated arm of 12 years old boy in 1962 and Tamai succeeded finger replantation in 1965. Since Jacobson and Suarez described superiority of small vessel repair using microscope, further advances in replantation occurrd with the develop-ment of suture material (18-20μ) and needles (65-120μ); making repair of vessels of 1 mm in diameter. The authors experienced four cases of traumatic amputation during the period from March, 1979 to Sept.. 1979 and the primary result of replantation is reported in this paper. 1. All cases were male and in the age group between 21 to 29. 2. Mode of amputation; two cases were amputated by presser, one case was by iron cutter and one was by paper cutter machine. 3. Tow out of four cases were incomplete amputation and two were complete multiple amputation. One case of multiple amputations was right four digits except thumb at the proximal phalanx level and the other was bilateral wrists. 4. The shortest duration of ischemia was four hours and 45 minutes and the longest was 13 and a half hours. 5. Four out of four replanted digits and two wrists were survived and the remains were failed. The possible cause of failure seems to be too long ischemic time. 6. Further functional results will be reported later.

수지(手指)에 발생한 Glomus Tumor - 치험 2례 보고 -

신경현,김준영,윤치순,최창욱,김학현 순천향의과대학 1978 Journal of Soonchunhyang Medical Science Vol.1 No.1

Glomus tbmor of the hand has been well documented lesion that usually presents as painful dermal nodule in the finger. Glomus tumor may be difficult in diagnostic and therapeutic problems because of relatively rare and not easily experienced cases. Normal glomus body presents in the skin and subcutis of the extremity, but the normal body is not more than 1 mm3) in size. Most evidence indicates that the main function of the normal glomus body is to aid in regulation of the skin circulation. The glomus tumor is thought to be an abnormal proliferation of the glomus body and accompained by the classic triad of symptoms : pain, tenderness and temperature sensitivity. This paper reports two cases of glomus tumor occurring in the nail bed and finger pulp. One case was found 30 years later & another case 15 years after the onset in spite of srvere pain, tenderness and lancinating pain when exposed to the cold tempera ture but the excision of the tumor resulted in complete recovery.

Proteomic Investigation of Seed Storage Proteins Among Korean Soybean Cultivars

Kesavan Markkandan,Bong Soo Park,Soon Ho Choi1,Hak Soo Seo 한국작물학회 2010 한국작물학회 학술발표대회 논문집 Vol.2010 No.04

and distribution of seed storage proteins are responsible for the quality of soybean and seed development. Among storage proteins, lipoxygenase isoforms (Mw. ~97 kDa) play a major role in the distinct bean flavor during storage. In this study, we compared three soybean elite cultivars viz., JIMPUM, JINPUM2 and TANMI2 (lipoxygenase null mutants, originated from Japan) along with WILLIAMS 82 (control plant, USA) to determine the seed storage proteins by proteomic approach. Phenotype of the mature seeds showed the variation in seed coat, color and appearance. Total seed proteins of the above cultivars were subjected to two dimensional gel electrophoresis (2-DE). The resulted protein profiling showed the intensity of the different quantitative spots varied among the four cultivars. We are now investigating by using other proteomic tool and the resulted difference in proteins may helpful in quality improvement or the functional roles in the seed development.

강우시 침투영향을 고려한 사면안정해석

심태섭,기완서,김선학,최순범 朝鮮大學校 建設技術硏究所 2007 建設技術硏究 Vol.27 No.2

Most of current slope safety analyses consider only the effect of the rise of underground water level. However, because the infiltration of surface water into the ground is believed to have significant effects on slope stability, the present study performed slope safety analysis in case of the rise of underground water level, the infiltration of surface water, and both resulting from rainfall, and examined their effects. For this study, we selected Slope A and B, at which slope failure had happened due to rainfall, and made slope safety analysis in consideration of the fall of wetting front and the rise of underground water level resulting from rainfall. Based on the results of the analysis, we made comparative analysis on the relation between the effect of infiltration on rainfall and the stability of the slopes and proposed a desirable slope safety analysis method. The conclusions of this study are as follows. 1. In slope safety analysis in consideration of the effect of infiltration resulting from rainfall, the variation of safety factor was different depending on whether to consider the fall of wetting front, the rise of underground water level. or both. 2. The decrease of the slope safety factor caused by the fall of wetting front on rainfall was somewhat faster than that caused by the rise of underground water level. This suggests that slope failure caused by rainfall is affected more by the fall of wetting front than by the rise of underground water level. 3. When both the fall of wetting front and the rise of underground water level were considered at the same time, the slope safety factor decreased faster than when either the fall of wetting front or the rise of underground water level was considered. Accordingly, it is considered desirable to consider both the fall of wetting front and the rise of underground water level in slope safety analysis that takes into account the effect of infiltration resulting from rainfall.