스티렌 폭로 근로자들의 기중 및 혈중 스티렌과 요중 만델산의 관계 분석

정호근,강성규,양정선,김기웅,이종성,조영숙,박인정 大韓産業醫學會 1994 대한직업환경의학회지 Vol.6 No.1

The concentration of styrene in air in blood and mandelic acid in urine were checked for the 60 workers with normal liver function, exposed to styrene. Styrene in air were sampled with personal air sampler at least 4 hours and analyzed by gas chromatography. Blood and spot urine were collected at the end of shift with a vacuum tube and a polythylene bottle and analyzed by gas chromatography and high performance liquid chromatography. Means of air and blood styrene and urine mandelic acid were 8.16 ppm(geometric mean), 0.199 mg/L, and 0.519 g/g creatinine, respectively. The concentration of styrene in air and mandelic acid in urine were high in the FRP factories and low in polymerization factory. Styrene in blood showed large difference by the working process. Styrene in air showed a good correlation with mandelic acid in urine(r=0.6369) and styrene in blood(r=0.6371). The mandelic acid in urine and styrene in blood corresponded to exposure of 50 ppm styrene were 0.890 g/g creatinine and 0.434 mg/L. However, hippuric acid in urine did not show any correlation with styrene in air. Urine mandelic acid excretion expected ratio showed a tendency to decrease according to obesity index and to increase with alcohol consumption.

瑕疵補修請求權에 관한 비교법적 검토

韓雄吉,盧永相,柳在南,鄭己鎬 동아대학교 법학연구소 1993 東亞法學 Vol.- No.15

산업대학 건축공학과 교육과정 개발에 관한 연구

임응찬,한인웅,이승준,박재호,조방현,서형수,정구용,한기원,김진원,임상규,이재윤 三陟大學校 1996 論文集 Vol.29 No.2

By impproving the educational program of the Department of Architectural Engineering and studying the theory of learning and the applied method necessary for the development of nation and society, we should develop a satisfying course of education to meet the demand and skill in the industralized society for the purpose of cultivating men of baility with great personalities and creative minds. Therefore, this study focused on classifying several kinds of occupations in the prart of architectured related to what graduates from the department of Architectural Engineering go with into the society. Accordingly after choosing some works adequate to each occupation by the proposed curricula, we tried to establish the scope of education and courses corresponding to the jobs and thus and develop a satisfying curriculum.

대학 건축공학과의 실습학기제에 관한 연구

이승준,한인웅,정구용,조방현,한기원,박재호,김진원 三陟大學校 2000 論文集 Vol.33 No.2

In order to solidify the architectural education in university, we should enlarge the opportunity of field training and develop the field training course system as a part of industry-scholastic cooperation. And we should develop new educational process to bring up potent engineers adaptable to the training affairs, faithful to the educational object of the industrial university.

感作 및 過敏性쇼크가 생쥐 腸 形質細胞에 미치는 영향

劉一晟,劉基善,鄭鎭雄 최신의학사 1968 最新醫學 Vol.11 No.10

The authors present here the following results_ showing the. effect of horse serum to plasma cells in lamina, propria. of duodenal vwi, using adult male mice seized with antibody-formation and anaphylactic shock ` by a normal horse serum injection. 1 . In normal group the plasma cells, counted 47.0 on an average in duodenal villi of mice, Type A of which counted 39.8; Type B 6.6; Type CO. 6. 2.In sensitized group the plasma cells counted 52.9, Types, A, B and C of which counted 44.9, _7.3 and 0.7 respectively, increasing by about 10% compared with normal group: 3. In anaphylactic shock group the plasma cells counted 42. 1, Types A, B and C of which counted 35. 8, 5.6 and 0.7, decreasing by about 10% compared with normal group.

우리나라 카드뮴 폭로 근로자들의 혈중, 요중 카드뮴과 누적폭로 추정량에 따른 신장장해 평가

강성규,양정선,김기웅,장재연,정호근 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1

88 workers exposed to cadmium were examined at the 12 factories using or producing cadmium in order to know the present state of cadmium exposure and renal dysfunction in 1992. Cadmium in blood and in urine were measured and compared by the 3 exposure level of cadmium in air. Cadmium in blood of low, moderate and high exposure group were 2.5, 3.8 and 7.6 ㎍/L, respectively. Cadmium in urine were 1.8(1.3), 3.8(2.6) and 7.9 ㎍/L(6.1 ㎍/g creatinine), respectively. However, there was no relationship between urinary cadmium and β₂-microglobulin. Cumulative exposure estimate(CEE) was calculated by multiplying the mean ambient cadmium level of the factory and working duration. CEE has a high correlation with cadmium in blood and urine, but no relation to β₂-microglobulin. Because working durations were relatively shorter than European workers', the highest CEE was just 300 ㎍·year/m³, which was not enough to induce renal tubular dysfunction. This study, however, suggested the possibility that renal tubular dysfunction caused by cadmium could be happened in Korea in the near future.

국내 카드뮴 취급 사업장의 카드뮴 폭로 실태 평가

강성규,홍정표,김기웅,장재연,정호근,정규철 大韓産業醫學會 1994 대한직업환경의학회지 Vol.6 No.2

Twenty-four factories registered at the Ministry of Labor as factories using or producing cadmium in 1991 were investigated to know the present state of occupational exposure to cadmium in 1992. Nine factories among 24 stopped using or changed to other substances and 1 factory didn't produce any more, but delivered it to other factories through imports. Therefore, only 14 factories were producing or using cadmium. But, alloying materials were supplied to about 20 and more factories, however, they couldn't be investigated because of limited information. Three factories had less than 50 workers were 3,6 had 50-300 and 5 had more than 300. About 167 workers were exposed to cadmium. According to the classification by process, there were 4 alloy processes, 2 refinary, 2 elctroplating, 2 dry cell making, 1 industrial battery making, 1 duplicator drum making, 1 recycling of battery and 1 copper refinary. 8 factories used metal cadmium, 3 cadmium oxide, 2 cadmium sulfide, and 1 cadmium hyroxide. One factory was importing cadmium stearates only and supplying them to the PVC making factories. The amount of metal cadmium producing in 2 refinary factories was about 50-65 ton per month. The other cadmium compounds were imported. According to exposure level of cadmium air of the 10 factories examined, each factory could be divided into high, moderate and low exposure groups. 1 battery recycling factory and 3 alloy factories were in the high exposure group and their mean air concentrations were 0.06679, 0.05481, 0.02492, and 0.003㎎/㎥, respectively. Refinary and industrial battery making factories were in the middle exposure group and their mean air concentrations were 0.00773 and 0.00613 ㎎/㎥, respectively. Finally, low exposure group were copper smelting, dry cell case making, duplicator drum making and electroplating factory and their mean air concentrations were 0.00096, 0.00071, 0.00057 and 0.00054 ㎎/㎥ respectively.

물질남용 치료프로그램 후 재범여부에 대한 예비적 추적조사 연구

김현수,조선미,오은영,임기영,정영기,윤웅장,이영미 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.6

연구목적: 본 연구는 물질사범에게 시행되는 수강명령 프로그램의 효과를 재범률을 중심으로 살펴보고자 한 것이다. 방 법: 이 연구의 대상집단은 보호관찰소에서 의뢰받은 물질남용자집단이다. 이들은 법원으로부터 보호관찰, 수강명령, 치료명령, 사회봉사 등을 부과받았다. 총 104명의 대상자집단을 치료프로그램을 이수한 수강군과 비수강군으로 나누었으며 이들에 대한 재범률을 조사하였다. 결 과: 프로그램을 이수한 수강군이 비수강군에 비해 재범률이 낮았다(p<.05). 또한 단기 수강군과 장기수강군의 재범률의 차이를 조사하였는데 대상자 집단의 수가 적기 때문에 장기 수강군의 효과가 통계적으로 입증되지는 않았다. 결 론: 우리는 물질남용자에 대한 정책이 보다 교육적으로 변화할 것을 본 논문을 통하여 제시하려 하였으며 정부 및 법무부는 물질남용자에게 교육과 치료를 제공해주어야만 한다. Objectives: Using recidivism rate, we investigated the outcome after our substance abuse treatment program had been implemented. Methods: Our target population was substance abuse criminals referred by probational office. They either received the parole and probation order, treatment order or social service order from the court. We divided 104 substance abuse criminals into treatment group and non-treatment group. We examined their recidivism rate. Results: We reached a conclusion that treatment group had lower recidivism rate than non-treatment group(p<.0.5). We examined the effectiveness of short-term and long-term programs. However, no effectivess of long-term program was found because the sabject number was too small. Conclusion: We suggest that the strategies for substance abuse should be changed to more educative ones. The Government and Ministry of Justice must provide education and treatment to the substance abuse criminals.

The Role of Radiation Therapy on Local Recurrence of Rectal Cancer

Woong Ki Chung,Sung Ja Ahn,Taek Keun Nam,Byung Sik Nah,Young Jin Kim 대한방사선종양학회 1992 Radiation Oncology Journal Vol.10 No.2

Ninety five patients of rectal cancer treated with surgery with or without adjuvant radiation therapy since January 1982 to December 1990 at the Chonnam University Hospital were analysed retrospectively regarding local failure. Of these 95 patients 72 patients were treated with surgery alone and remaining 23 patients received postoperative radiation therapy to pelvis. There were 45 men and 50 women with 53 years of median age. Minimum follow-up period was 19 months and median was 47 months (range, 19-125 months). Kaplan-Meier method was used to calculate actuarial risk of local recurrence and survival rate. Comparison between two groups was evaluated by Log rank test. Of total 95 patients twenty seven patients (28.4%) developed local recurrence and 13 patients (17.3%) developed local and distant metastasis concomitantly. Eighty nine percent (24/27) of patients developed local recurrence within 24 months. Pelvic organ adjacent to the primary tumor area was the most common site of initial local recurrence. Of 72 patients treated with surgery alone local recurrence developed in 24 patients. Of 17 patients with stage A and B1(Gunderson - Sosin modification of Dukes' staging system) 6 patients experienced local recurrence (31.2%). The local recurrence rate of B2 and B3 group was 29.9% (7/33) and that of C2 and C3 was 54.7% (11/19), respectively. There was statistically significant difference between two groups (p<0.05). Of 23 patients treated with definitive surgery and radiation therapy 10% (1/10) recurred in B2 and B3 patients. This was slightly lower than C2 and C3 patients (22.2%, 2/10) of similar policy, but revealed no statistically significant difference (p>0.05). In the patients of B2+3 local failure rate decreased when radiation therapy was added (29.9%) vs 10%, p>0.05) and also similar results in C2+3 group (34.7% vs 22.2%, p<0.05). The local failure rate in relation to distance from the anal verge had verge had no statistically significant difference.

Comparison of Monthly Ibandronate Versus Weekly Risedronate in Preference, Convenience, and Bone Turnover Markers in Korean Postmenopausal Osteoporotic Women

Chung, Yoon-Sok,Lim, Sung-Kil,Chung, Ho-Yeon,Lee, In-Kyu,Park, Il-Hyung,Kim, Ghi-Su,Min, Yong-Ki,Kang, Moo-Il,Chung, Dong-Jin,Kim, Yong-Ki,Choi, Woong Hwan,Shong, Min Ho,Park, Ji-Hyun,Byun, Dong-Won,Y Springer-Verlag 2009 Calcified tissue international Vol.85 No.5

<P>Patient preferences, convenience, and bone turnover markers were evaluated for the monthly ibandronate over the weekly risedronate regimen in Korean postmenopausal osteoporotic women. This was a 6-month, prospective, randomized, open-label, multicenter study with a two-period and two-sequence crossover treatment design. After a 30-day screening period, eligible participants with postmenopausal osteoporosis were randomized to receive either monthly oral ibandronate 150 mg for 3 months followed by weekly oral risedronate 35 mg for 12 weeks (sequence A) or the same regimen in reverse order (sequence B). Patient preference and convenience were evaluated by questionnaire. The changes in serum C-telopeptide after 3 months of treatment were analyzed. A total of 365 patients were enrolled in this study (sequence A 182, sequence B 183). Of patients expressing a preference (83.4%), 74.8% preferred the monthly ibandronate regimen over the weekly regimen (25.2%). More women stated that the monthly ibandronate regimen was more convenient (84.2%) than the weekly regimen (15.8%). There was no significant difference in the change in bone turnover marker between the two treatments. The two regimens were similarly tolerable. There were fewer adverse events in the monthly ibandronate group compared to the weekly risedronate group in terms of gastrointestinal side effects (nausea and abdominal distension). This study revealed a strong preference and convenience for monthly ibandronate over weekly risedronate in Korean postmenopausal osteoporotic women. There was no significant difference in change of bone turnover marker and safety profile between the two regimens.</P>