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Kodak 649F Plates를 이용한 Dichromated Gelatin 홀로그래픽 감광재 처리 방법 연구
임용석,이영락,최옥식 嶺南大學校 基礎科學硏究所 1995 基礎科學硏究 Vol.15 No.-
Dichromated gelatin plays an important role to fabricate various kinds of holographic optical elements. In this study, we have investigated the processing method and the characteristics of dichromated gelatin recording materials by using Kodak 649F plates. The processing methods for obtaining high diffraction efficiencies and environmental stability which are necessary for the fabrication of the holographic optical elements are presented. Exposure characteristics, spectral and angular sensitivity, and the degradation of the diffraction efficiency versus time are measured. The maximum diffraction efficiency of the obtained holographic grating is about 90%.
지역 사회 감염성 폐렴에서 Cefodizime의 효능 및 안전성을 Ceftriaxone과 비교한 연구
심영수,오명돈,한성구,최강원,정희순,김영환,유철규,최형석 대한감염학회 1994 감염 Vol.26 No.3
목적: Cefodizime은 새로운 주사용 제 3세대 항생제이다. 저자들은 감염성 폐렴 환자들에서 이 약물을 하루 1번 정맥주사하였을 때 관찰되는 임상적및 세균학적 효과와 안전성을 ceftriazone과 비교하기 위하여 본 연구를 시행하였다. 방법: 1992년 6월부터 1993년 11월까지 서울대학교 병원에 지역사회 감염성 폐렴으로 입원하였던 환자 32명을 무작위로 3군으로 나누고 제 1군 : Cefodizime 1g(n=11), 제2군 : Cefodizime 2g(n=10), 제3군 : Ceftrizxone 1g(n=11)을 각각 하루 1회 정맥주사로 투여하여 그 치료율및 안전성을 비교하였다. 결과: 1)Cefodizime은 제1군 100%, 제2군 80.0%의 임상적 반응율을 보였다. Ceftriaxone을 투여하였던 제 3군에서는 81.8%의 임상적 반응율을 보였다. 이러한 임상적 반응율의 결과는 세 군간에 통계적으로 유의한 차이를 보이지 않았다(p>0.05). 2)세균학적 반응율도 세 군간에 유의한 차이를 보이지 않았다. 3)Cefodizime의 안전성의 평가에서 제1군 및 제2군에서 구토 및 오심이 2예(9.5%)에서 관찰되었고 일시적인 간효소치의 상승이 1예(4.8%)에서 관찰되었다. 경미한 공복시 위통이 1예(4.8%)에서 관찰되었다. Ceftriaxone으로 치료한 군에서는 특별한 부작용은 관찰되지 않았다. 결론: 이상의 결과로 지역사회 감염성 폐렴의 치료에 있어서 cefodizime 1내지 2g을 정맥 주사로 하루 1회 치료할 경우 적어도 ceftriaxone과 유사하게 효과적이며 안전한 것으로 사료된다. Background:Cefodizime(Modivid) is a new parenteral form of cephalosporin showing the antibacterial specturm of the third generation. The clinical efficacy and safety of cefodizime have been well proven by some previous clinical studies performed in European countries and Japan. The objective of this study was to evaluate the clinical, radiological and antimicrobial efficacy of this drug in patients with community-acquired pneumonia compared to that of ceftriaxone. Methods: We performed an open, controlled, randomized study in 32 patients with community-acquired pneumonia at Seoul national University hospital from June 1992 to November 1993. In the first group(n=11) 1g of cefodizime, and in the second group(n=10) 2g of cefodizime were respectively administered intravenously once a day. and in the third group(n=11), 1g of ceftriaxone was administered intravenously. Results: The results were as follows. 1) Cefodizime showed the clinical response rate of 100% in group I, and 80.0% in group Ⅱ. The clinical response rate of ceftriaxone in group Ⅲ was 81.8%. There was no significant statistical difference(p>0.05). 2) The rates of bacteriological efficacy wee not statistically different among three groups. 3) In the cefodizime treatment group(group Ⅰ, group Ⅱ) nausea and vomiting were observed in 2 cases(9.5%) and transient elevations of hepatic transaminases in 1 case(4.8%). Mild abdominal pain occurred in 1 case(4.8%). No significant adverse reactions were observed in the ceftriaxone treatment group. Conclusion: We could conclude that once a day intravenous cefodizime therapy was as effective and well tolerated as ceftriaxone in the treatment of community-acquired pneumonia.
LC : Noninvasive Fibrosis Panels Predict 5-year Outcomes of Chronic Hepatitis B; Preliminary Study
( Young Baek Kim ),( Jeong Han Kim ),( Hong Seok Choi ),( Yong Hwang ),( Yong Hoon Choi ),( Jun Jae Kim ),( Seo Jung Woong ),( Soon Young Ko ),( Won Hyeok Choe ),( So Young Kwon ) 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1
Background: In patients with chronic liver disease, level of fi- brosis predicts liver-related complication and survival. Previous report (Gastroenterology 2011;140:1970-1979) showed noninvasive tests for fibrosis predict 5-year survival of patients with chronic hepatitis C. We aimed to evaluated abilities of noninvasive tests for fibrosis to predict overall survival with a 5-year period in chronic hepatitis B (CHB) patients. Methods: The medical records of CHB patients visited Konkuk University Medical Center in year 2005. APRI and FIB-4 were calculated as previously described elsewhere. Kaplan- Meier survival analysis and log rank test were used to analyze correlation of these tests and patient`s survival. Results: Total 218 patients were included for analysis and of these, 26 patients were deceased within 5 year follow up period. Male patients were 138 (63.3%) and mean age was 47.7 years. HBeAg positive patients were 135 (61.9%) and underlying cirrhotic patients were 91 (41.7%). Mean value of APRI was 1.7 and that of FIB-4 was 3.8. If cut-off level of APRI was set as 0.72, P-value was 0.0086 and hazard ratio was 2.7603 (95% CI, 1.2433-6.1279). If cut-off level of FIB-4 was set as 2.32, p-value was 0.0007 and hazard ratio was 3.6904 (95% CI, 1.6380- 8.3147) Conclusions: Noninvasive test for liver fibrosis, such as APRI and FIB-4 can help prediction of 5 year survival of CHB patients. Large scale cohort analysis is warranted.
The Dairy Calves Mortality : the Causes of Death during Ten Yearsin a Large Dairy Farm
Tai Young Hur,Young–,Hun Jung,Seog–,Jin Kang,Chang yong Choe,Ui Hyung Kim,Il Sun Ryu,Dong Soo Son,Kwang Soo Baek,Kwang Seok Ki,Hyun June Lee,Eung Gi Kwon,Guk Hyun Suh,Young Il Cho 대한수의학회 2012 대한수의학회 학술대회발표집 Vol.2012 No.-
High-speed waveguide photodetector for 64 Gbaud coherent receiver
Ko, Young-Ho,Choe, Joong-Seon,Han, Won Seok,Lee, Seo-Young,Han, Young-Tak,Jung, Hyun-Do,Youn, Chun Ju,Kim, Jong-Hoi,Baek, Yongsoon The Optical Society 2018 Optics letters Vol.43 No.3
<P>A high-speed waveguide photodetector has been successfully fabricated for an integrated coherent receiver. Dual laterally tapered structures are introduced for a spot-size converter. We optimize the responsivity and the polarization-dependent loss of the spot-size converter-integrated waveguide photodetector through the beam propagation method simulation. The waveguide photodetector is designed with electrical as well as optical optimizations. The photodetector provides sufficient alignment tolerance, high responsivity of 0.73 A/ W, and low polarization-dependent loss of 0.27 dB, which is in good agreement with the simulation results. By increasing the thickness of the matching layer and the n-doped upper taper, the electrical properties of the photodetector are enhanced. The photodetector has a 3 dB bandwidth of 45 GHz, providing high-speed operation. Through the electrical and optical optimizations, we successfully obtain the high-speed waveguide photodetector for a 64 Gbaud integrated coherent receiver. (C) 2018 Optical Society of America</P>
연구논문 : 두메양귀비(Papaver radicatum var. pseudoradicatum) 종자의 발아특성과 초기생장에 관한 연구
안영희 ( Young Hee Ahn ),손자은 ( Ja Eun Son ),이성제 ( Sung Je Lee ),김영화 ( Ying Hua Jin ),최창용 ( Chang Yong Choe ),이경미 ( Kyung Mee Lee ),김미영 ( Mee Young Kim ),이석창 ( Seok Chang Lee ) 한국환경과학회 2011 한국환경과학회지 Vol.20 No.4
This experiment was held to identify the germination feature of Papaver radicatum var. pseudoradicatum which has high economical value. Seeds were collected in the Mt. Changbai in China. To eliminate dormancy of the seeds, chilling treatment were carried out in the 5℃ refrigerator. 30 days, 60 days, 90 days, 120 days of chilling treatments were taken. After being Treated, seeds were under 15, 20, 25℃ of temperature and light, dark conditions respectively to see the differences in germination. Within many features, germination ratio of seeds and germination period were investigated. Also, features related to early growth were checked through the closer look into acrospire, growth of cotyledon of young plant. Over 30 days of chilling treatment was all effective. Especially, 120 days of chilling treatment was most effective. The seeds germinated well in the light conditions. 120 days of chilling treatment, 15℃, light conditions were found to be most effective conditions as 54.5% of the seeds germinated. The germination period was 4.29 days. 30 days after germinating, length of the aerial part had been 1.90 cm. But after 45 days, the length grew rapidly to 4.58 cm. Fresh weight of scales plant was also increased dramatically after 45 days. Therefore, transporting the plant 45 days after seeding judged to be good.
( Hong Seok Choi ),( Jeong Han Kim* ),( Yong Hwang ),( Yong Hoon Choi ),( Young Baek Kim ),( Jun Jae Kim ),( Mi Jin Hong ),( Soon Young Ko ),( Won Hyeok Choe ),( So Young Kwon ) 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1
Background: Hepatocellular carcinoma (HCC) has high risk of recurrence after curative therapy and inflammation process involves progression of HCC. We aimed to investigate inflammatory marker that can predict HCC recurrence after radiofrequency ablation (RFA) for curative intent. Methods: We retrospectively reviewed the medical records of HCC patients treated with RFA at Konkuk University Medical Center from year 2005 to 2010. The last follow up was August 2012. The patients were divided according to recurrence and baseline characteristics including white blood cell (WBC) count with fraction and C-reactive protein (CRP) compared. Results: Total 62 patients were included for analysis. There were 26 cases of recurrence (41.9%). Thirty nine patients (62.9%) were male and the most common etiology was hepatitis B (n=48, 77.4%). When we compared recurrence group with non-recurrence group, Child-Pugh score (6.1±1.4 vs. 5.3±0.8, P=0.015), monocyte fraction of WBC (8.1±2.4% vs. 6.7±2.7%, P=0.041), prothrombin time (PT, INR; 1.3±0.2 vs. 1.2±0.2, P=0.040) were higher and albumin (3.4±0.6 g/dL vs. 3.8±0.5 g/ dL, P=0.036) was lower. Other baseline characteristics including neutrophil fraction, lymphocyte fraction and CRP were not significantly different between groups. Area under receiver operating curve (AUROC) of monocyte fraction was 0.675 and if we choose cut-off level of monocyte fraction as 7.1%, Kaplan- Meier analysis with log-rank test showed significant difference for recurrence (P=0.006). Conclusions: High monocyte fraction reflects increased risk of HCC recurrence after RFA. These patients need careful observation during follow up period and underlying mechanism have to be investigated.