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Familial Creutzfeldt-Jakob Disease with V180I Mutation
양태일,정대수,안보영,정병훈,조한정,김용선,나덕렬,Michael D. Geschwind,김은주 대한의학회 2010 Journal of Korean medical science Vol.25 No.7
Creutzfeldt-Jakob disease (CJD) is an uncommon neurodegenerative disorder with an incidence of 1 per 1000,000 per year typically characterized by rapidly progressive dementia, ataxia, myoclonus and behavioral changes. Genetic prion diseases, which develop due to a mutations in the prion protein gene (PRNP), account for an estimated 10 to 15% of all CJD cases. We report a 75-yr-old woman with familial CJD carrying a V180I mutation which features late onset, slow progression, no periodic sharp wave complexes on electroencephalography, and extensive cortical ribboning with spared the cerebellum and the medial occipital lobes posterior to the parieto-occipital sulcus on MRI. To our knowledge, this is the first documented case of a point mutation at codon 180 in South Korea.
양태일,박영은,김종국,차성이,김태형,김대성 대한신경과학회 2010 대한신경과학회지 Vol.28 No.4
The presence of serum antibodies to various gangliosides, such as anti-GQ1b, is closely related to the clinical features of Guillain‐Barré syndrome. However, the phenotype associated with anti-GT1a IgG has not yet been determined, although it has been detected in some cases of the pharyngeal-cervical‐brachial variant. We report herein two patients harboring anti-GT1a IgG who both presented with profound dyspnea, dysphagia, and quadriparesis. The findings of this report suggest that the anti-GT1a antibody specifies a clinical feature of oropharyngeal palsy.
뇌경색과 거미막밑출혈이 동시에 발생하여 우회로조성술과 코일색전술로 치료한 전대뇌동맥박리
양태일,노경하,박민규,오세진,백승국,이상원,박경필 대한신경과학회 2012 대한신경과학회지 Vol.30 No.2
Anterior cerebral artery (ACA) dissection with simultaneous subarachnoid hemorrhage (SAH) and cerebral infarction is very rare and its treatment continues to be debates. We present a case of simultaneous SAH and cerebral infarction caused by dissection of the ACA that was successfully treated by bypass surgery and an endovascular procedure.
양태연(梁太姸),손지유(孫志侑),한기순(韓起順),박인호(朴仁皓) 서울대학교 교육연구소 2016 아시아교육연구 Vol.17 No.4
본 연구는 영재아들의 다양한 심리환경적 요인 중에 어떠한 요인의 상담이 필요한지를 진단하기 위한 영재상담 진단 검사 도구를 개발하는데 목적이 있다. 이를 위해 영재교육기관에서 영재교육을 받고 있는 초등 영재아 120명과 중등 영재아 168명을 대상으로 연구를 실시하였으며, 반구조화된 설문과 이론적 고찰을 통하여 103문항의 예비문항을 추출하였다. 이를 토대로 문항분석과 탐색적 요인분석을 실시하여 11개요인 총 46문항을 추출하였다. 확인적 요인분석 결과, 모형 적합도는 x<SUP>2</SUP> =1419.685 (df=882, p=.00), TLI=.911, CFI=.924, RMSEA=.046으로 나타나 적합도 지수는 양호한 값을 보이는 것으로 나타났다. 각 하위요인의 내적합치도인 Cronbach의 α 역시 부모님 관계 및 부모와의 갈등 .68, 형제자매와의 관계 .76, 학업과중 및 시간부족 .85, 영재성 및 영재교육 .83, 이성친구 .70, 친구관계 .83, 진로문제 .86, 학교부적응 .74, 학교수업 및 학교생활 만족도 .82, 성적 및 학업 .90, 학원에 대한 부담감 및 거부감 .86으로 나타나 개발된 척도가 영재들의 상담을 위한 진단 도구로서 타당하고 신뢰로운 검사도구임을 알 수 있었다. 본 연구결과는 초/중등 영재들의 개인 심리환경적 상담 및 진로/학업 상담을 돕는데 활용될 수 있을 것으로 사료된다. This research aims to develop a diagnostic test tool for the gifted children to determine, among various psychological-environmental factors, which specific factors need counseling. The research is conducted among 120 gifted elementary schoolers and 168 gifted middle schoolers, and 103 candidate questions are extracted through semi-structured survey and theoretical contemplation. Based on the candidate questions, item analysis and exploratory factor analysis are implemented and total of 46 questions over 11 factors are selected. A result of confirmatory factor analysis shows the model fitness of 1419.685 (df=882, p=.00), TLI=.911, CFI=.924, RMSEA=.046, which is a satisfactory fitness value. Cronbach’s α, value of internal consistency, for each sub factor are 0.64 for parents’ relationship and conflicts with parents, 0.74 for relationship with siblings, 0.85 for excessive assignments and lack of time, 0.82 for giftedness and gifted education, 0.66 for opposite-sex friendships, 0.82 for friendships, 0.86 for future plans, 0.68 for misfitting in school, 0.82 for school classes and school life satisfaction, 0.90 for grades and school work, and 0.85 for stress and resistance regarding private educational institutes; suggesting the developed test is a fair and reasonable diagnostic tool for counseling the gifted children. The result of this research is expected to be used for psychological-environmental counseling of the gifted elementary/middle schoolers.
양태선 한국교양교육학회 2018 교양교육연구 Vol.12 No.1
The purpose of the study was to investigate students’ general perceptions about a student-professor writing conference which had not been widely practiced in Korea and its impact on students’ writing performance. A professor and 5 university students including 2 male and 3 female students who took a general English writing class at A university were the participants of the study. To understand how students perceived a student-professor writing conference, semi-structured interviews were carried out and writing conferences and pretest and posttest were conducted to see the role of writing conferences in students’ process of learning writing and its influence on their writing performance. The results revealed that holding a writing conference was beneficial to students in that it could help students develop a sense of autonomy in their learning process and become aware of learning strategies employed in the writing process. Furthermore, writing conferences had a positive influence on students writing performance, especially on how to organize an effective paragraph. The following suggestions were made based on the results of the study. First, professors should implement writing conferences in their instruction. Second, more attention should be paid to how to successfully embed grammar, mechanics, and word choice in writing instruction. Third, professors should offer students a guideline which can show characteristics and purposes of writing conferences, and the respective roles of the participants in order to make them ready for and active during writing conferences. Lastly, the university should also make an effort to lessen a burden on professors and students by establishing an English writing center and providing teaching assistants.
냉각수 유동을 고려한 핵연료 조사 리그의 조립 플러그 설계
양태호,홍진태 한국기계기술학회 2017 한국기계기술학회지 Vol.19 No.1
In this paper, a structural integrity on the test rig with assembly plug to perform intermediate examination is evaluated. Structural analysis results between the test rig with non assembly plug and assembly plug are compared, because the assembly plug has an effect on the flow of the coolant in the test rig. A equivalent stress value on the test rig with assembly plug is increased more than the stress on the test rig with non-assembly plug. A shape optimization of the assembly plug is performed to decrease the stress. Considering a connection with the transport tool, a optimized shape of the assembly plug is presented to minimize the stress on the test rig. Using the optimized assembly plug, the equivalent stress on the test rig with the optimized plug is less than the stress on the test rig with the non-optimized plug.