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정병훈,신운식,김경식 中央醫學社 1989 中央醫學 Vol.54 No.5
Since the scapular flap was described by dos Santos and clinically implemented by Alain Gilbert, it has generally been utilized with no functional donor site morbidity. We have experienced sixteen cases involving various parts of the body such as jaw, neck, axilla, upper and lower extremities. Of them fifteen flaps were transfered successfully and one was failed because of recipient's arterial insufficiency. In this paper we presented a series of sixteen treated cases along with recommended methods for dissecting the flap, and an analysis of its advantages and disadvantages with related references.
콘크리트 構造物의 龜裂發生 原因과 制御 및 對策에 관한 考察
鄭秉勳,鄭世煥 부천대학 1996 論文集 Vol.17 No.-
It is impossible completely to prevent cracking in concrete structures and its problems cannot be solved by one or two countermeasures as long as using concrete. The cracks in concrete spoil the outward appearance and lead to the deterioration of the watertightness and bring about the degradation of capability in the load carrying capacity and the durability in concrete structures. Therefore, it must be achieved to inclusively comprehend and to study for the causes of cracks. And also it is judged that the effective countermeasures for the control of cracks can be established by the continuous research for cracks and the study and the development of the new material which have the strong resistance for cracks. Above all, it is thought that the preparatory prevention against cracks is most important.
정병훈 淸州敎育大學校 科學敎育硏究所 1998 科學과 數學敎育論文集 Vol.19 No.-
In this treatise we discussed two programs which were invented for scientific gifted students both in elementary and lower secondary level. One of them focused on the training of scientific thinking skills which develop an ability of the theoretical modeling through observations and simple experiments. In a classroom teacher shows some related phenomenon about theme and usually does not explain the theory. Students should explain the observed phenomenon and suggest a theoretically consistent and 'eigen' model. They discuss their models and then choose the best one. Through such activities they experience the process of selecting the optimal model in the 'sea of controversial theories' as like a scientific researcher. On the other hand, the second one mainly aimed at a group inquiry and a theoretical competition between the research groups. Students organize of themselves a research group and investigate the possible solutions of given problems. It was a long term project type activity. In conclusion, it was discussed that such programs should be more offered for developing the creative thinking skills.
Genetic Studies in Human Prion Diseases
정병훈,김용선 대한의학회 2014 Journal of Korean medical science Vol.29 No.5
Human prion diseases are fatal neurodegenerative disorders that are characterized byspongiform changes, astrogliosis, and the accumulation of an abnormal prion protein(PrPSc). Approximately 10%-15% of human prion diseases are familial variants that arecaused by pathogenic mutations in the prion protein gene (PRNP). Point mutations or theinsertions of one or more copies of a 24 bp repeat are associated with familial human priondiseases including familial Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinkersyndrome, and fatal familial insomnia. These mutations vary significantly in frequencybetween countries. Here, we compare the frequency of PRNP mutations betweenEuropean countries and East Asians. Associations between single nucleotide polymorphisms(SNPs) of several candidate genes including PRNP and CJD have been reported. The SNP ofPRNP at codon 129 has been shown to be associated with sporadic, iatrogenic, and variantCJD. The SNPs of several genes other than PRNP have been showed contradictory results. Case-control studies and genome-wide association studies have also been performed toidentify candidate genes correlated with variant and/or sporadic CJD. This review providesa general overview of the genetic mutations and polymorphisms that have been analyzedin association with human prion diseases to date.
초등학교「슬기로운 생활」및 「자연」과 소재의 선정과 학습지도에 관하여 : '자석'단원의 내용과 지도를 중심으로 Mainly about 'Magnet'
정병훈 淸州敎育大學校 科學敎育硏究所 1996 科學과 數學敎育論文集 Vol.17 No.-
교육과정의 변화에 따른 초등학교 자연과 학습 소재의 선정과 지도 내용에 대하여 '자석'단원을 중심으로 조사하였다. 조사 대상은 1953년도 발간된 교수요목기부터 1995년 6차 교육과정까지 초등학교 1,2학년의 자연과의 슬기로운 생활의 교육과정과 교과서에서 취급하고 있는 '자석'에 관련된 단원이다. 연구결과 자석 단원의 소재와 내용은 3차 교육과정을 제외하고 교육과정의 개편에 따른 큰 영향을 받지 않았으며 시대적 변화에 따른 소재의 문화적 ·기술적·사회적 변화를 충실하게 반영하고 있지 못하였다. 또한 자석의 개념이 대단히 추상적인 것임에 비하여 자석현상을 1, 2학년에서만 취급하고 있고 고등학교 졸업할 때까지 영구자석에 대해서는 한번도 취급하지 않고 있다는 문제점을 나타내고 있다. 본 연구에서는 자석의 개념을 가르치는데 있어서 존재하는 근본적인 어려움에 대하여 언급하였으며, 이를 극복하기 위한 몇 가지 방안을 제안하였다.
1774년 독일 반제도의 『입문서(Elementarwerk)』가 과학교육에서 차지하는 위치
정병훈 淸州敎育大學校 科學敎育硏究所 2003 科學과 數學敎育論文集 Vol.24 No.-
J. B. Basedow is a German educational reformer who advocated the realistic teaching methods and the introduction of nature study, physical education, and manual training in the school. In 1768 Basedow published an acclaimed monograph demanding educational reform and calling for creation of a laboratory school for training teachers in his methods. Basedow's views were influnced by the writings of J. A. Comenius, J. Locke, and J. J Rousseau. Basedow's 'Elementarwerk' or "Elements of Education", a study of encyclopedic world view as a part of elementary education, published in 1774 reflects those philanthropic thoughts and modern science education. He estabilished a philanthropic school in Dessau in 1774. In imitation of the school at Dessau institutions called Philanthropin were established at various places and those who held Basedow's pedagogical opinions were called Philanthropen, or Philanthropisten. The only Philanthropin that prospered and still exists was that founded by Salzmann at Schnepfenthal in the Duchy of Gotha. Christian Gotthilf Salzmann was one of the most distinguished pedagogues of the Philanthropinst school. Basedows practical teaching methods had become by the early 19th century a fundamental force in Germany's public school systems. His reforms were widely influential and similar institutions were established throughout Germany and Switzerland.