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정병훈,신운식,김경식 中央醫學社 1989 中央醫學 Vol.54 No.5
Since the scapular flap was described by dos Santos and clinically implemented by Alain Gilbert, it has generally been utilized with no functional donor site morbidity. We have experienced sixteen cases involving various parts of the body such as jaw, neck, axilla, upper and lower extremities. Of them fifteen flaps were transfered successfully and one was failed because of recipient's arterial insufficiency. In this paper we presented a series of sixteen treated cases along with recommended methods for dissecting the flap, and an analysis of its advantages and disadvantages with related references.
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鄭秉勳,鄭世煥 부천대학 1997 論文集 Vol.18 No.-
Cracks in concrete structures is inevitable. Actually the reinforcement of steel in concrete is on the assumption that cracks come into existence. There are many causes of cracking in concrete structures. When the hardened concrete is applied by exessive forces, cracks in concrete are formed by lack of its own resistance and also formed by dint of the internal stress in the fresh concrete which is not applied by external forces. Cracks happen in concrete structures may bring about many problems. These cracks may simply spoil the outward appearance and also may lead to the structural harm and the damage of durability in concrete structures. Therefore the causes of cracks happen in concrete structures have to be synthetically investigated and analyzed and the state of cracks have to be estimated. And also the pertinent countermeasures for cracks have to be established. It is not easy to examine closely the causes of cracks in concrete because cracks happen by overlapping with various causes and appear by the complicated interaction. Therefore it is thought that to grasp the causes of cracks most greatly damage to the concrete structures and to analyze structures by virtue of it are effective. And also the cracks in structures show the various and distinguished patterns according to causes. Therefore the patterns and feature of cracks in concrete have to uprightly be investigated and grasped and it is judged that to presume the causes of cracks on the basis of the patterns and feature of cracks in concrete are necessary.
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Genetic Studies in Human Prion Diseases
정병훈,김용선 대한의학회 2014 Journal of Korean medical science Vol.29 No.5
Human prion diseases are fatal neurodegenerative disorders that are characterized byspongiform changes, astrogliosis, and the accumulation of an abnormal prion protein(PrPSc). Approximately 10%-15% of human prion diseases are familial variants that arecaused by pathogenic mutations in the prion protein gene (PRNP). Point mutations or theinsertions of one or more copies of a 24 bp repeat are associated with familial human priondiseases including familial Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinkersyndrome, and fatal familial insomnia. These mutations vary significantly in frequencybetween countries. Here, we compare the frequency of PRNP mutations betweenEuropean countries and East Asians. Associations between single nucleotide polymorphisms(SNPs) of several candidate genes including PRNP and CJD have been reported. The SNP ofPRNP at codon 129 has been shown to be associated with sporadic, iatrogenic, and variantCJD. The SNPs of several genes other than PRNP have been showed contradictory results. Case-control studies and genome-wide association studies have also been performed toidentify candidate genes correlated with variant and/or sporadic CJD. This review providesa general overview of the genetic mutations and polymorphisms that have been analyzedin association with human prion diseases to date.
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초등학교「슬기로운 생활」및 「자연」과 소재의 선정과 학습지도에 관하여 : '자석'단원의 내용과 지도를 중심으로 Mainly about 'Magnet'
정병훈 淸州敎育大學校 科學敎育硏究所 1996 科學과 數學敎育論文集 Vol.17 No.-
교육과정의 변화에 따른 초등학교 자연과 학습 소재의 선정과 지도 내용에 대하여 '자석'단원을 중심으로 조사하였다. 조사 대상은 1953년도 발간된 교수요목기부터 1995년 6차 교육과정까지 초등학교 1,2학년의 자연과의 슬기로운 생활의 교육과정과 교과서에서 취급하고 있는 '자석'에 관련된 단원이다. 연구결과 자석 단원의 소재와 내용은 3차 교육과정을 제외하고 교육과정의 개편에 따른 큰 영향을 받지 않았으며 시대적 변화에 따른 소재의 문화적 ·기술적·사회적 변화를 충실하게 반영하고 있지 못하였다. 또한 자석의 개념이 대단히 추상적인 것임에 비하여 자석현상을 1, 2학년에서만 취급하고 있고 고등학교 졸업할 때까지 영구자석에 대해서는 한번도 취급하지 않고 있다는 문제점을 나타내고 있다. 본 연구에서는 자석의 개념을 가르치는데 있어서 존재하는 근본적인 어려움에 대하여 언급하였으며, 이를 극복하기 위한 몇 가지 방안을 제안하였다.
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정병훈 淸州敎育大學校 科學敎育硏究所 1998 科學과 數學敎育論文集 Vol.19 No.-
In this treatise we discussed two programs which were invented for scientific gifted students both in elementary and lower secondary level. One of them focused on the training of scientific thinking skills which develop an ability of the theoretical modeling through observations and simple experiments. In a classroom teacher shows some related phenomenon about theme and usually does not explain the theory. Students should explain the observed phenomenon and suggest a theoretically consistent and 'eigen' model. They discuss their models and then choose the best one. Through such activities they experience the process of selecting the optimal model in the 'sea of controversial theories' as like a scientific researcher. On the other hand, the second one mainly aimed at a group inquiry and a theoretical competition between the research groups. Students organize of themselves a research group and investigate the possible solutions of given problems. It was a long term project type activity. In conclusion, it was discussed that such programs should be more offered for developing the creative thinking skills.
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