http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
돼지 지방 조직 및 골수 유래 성체줄기세포의 성상분석과 다능성에 관한 연구
이아영,최경임,나진주,소병재,이경우,장기윤,송재영,차상호,Lee, Ah-Young,Choe, Gyeong-Im,Nah, Jin-Ju,So, ByungJae,Lee, Kyung-Woo,Chang, Ki-Yoon,Song, Jae-Young,Cha, Sang-Ho 대한수의학회 2013 大韓獸醫學會誌 Vol.53 No.1
Mesenchymal stem cells (MSCs) have ability to differentiate into multi-lineage cells, which confer a great promise for regenerative medicine to the cells. The aim of this study was to establish a method for isolation and characterization of adipose tissue-derived MSC (pAD-MSC) and bone marrow-derived MSC (pBM-MSC) in pigs. Isolated cells from all tissues were positive for CD29, CD44, CD90 and CD105, but negative for hematopoietic stem cell associated markers, CD45. In addition, the cells expressed the transcription factors, such as Oct4, Sox2, and Nanog by RT-PCR. pAD-MSC and pBM-MSC at early passage successfully differentiated into chondrocytes, osteocytes and adipocytes. Collectively, pig AD-MSC and BM-MSC with multipotency were optimized in our study.
김경엽,김종호,이현경,김하영,문보연,이유란,박중원,소병재,배유찬,Kim, Gyeongyeob,Kim, Jongho,Lee, Hyunkyoung,Kim, Ha-Young,Moon, Bo-Youn,Lee, Yu-Ran,Park, Jungwon,So, Byungjae,Bae, Youchan 대한수의학회 2022 大韓獸醫學會誌 Vol.62 No.1
This paper describes a fatal case of pneumonia in a 14-day-old dog caused by extraintestinal pathogenic Escherichia coli (ExPEC). The necropsy showed that almost all of left lobes of the lungs had dark-red consolidation. A histopathology examination revealed moderate acute fibrino-hemorrhagic necrotizing pneumonia with intralesional bacterial colonies. Non-suppurative epicarditis, congestion in the liver, and necrosis in the white pulp of the spleen also were found. E. coli with cytotoxic necrotizing factor 1 and α-hemolysin was isolated from the lung. This case was confirmed to have fatal pneumonia caused by ExPEC that led to a systemic infection.
토끼에서 Pasteurella multocida 감염에 의한 뇌막뇌염과 폐렴 증례보고
정지연,이경현,최은진,김하영,손준형,소병재,정지열,Jeong, Jiyeon,Lee, Kyunghyun,Choi, Eun-Jin,Kim, Ha-Young,Sohn, Jun Hyung,So, ByungJae,Jung, Ji-Youl 대한수의학회 2018 大韓獸醫學會誌 Vol.58 No.1
Eight rabbits exhibited head tilt and subsequently died. At necropsy, three rabbits had crusty deposits in ears and four had reddish lungs. The main histopathological features were severe diffuse suppurative meningoencephalitis (75.0% of rabbits), fibrinopurulent pneumonia (37.5%), and otitis externa (37.5%). Pasteurella multocida (P. multocida) was isolated from brains, ears, and lungs. The capsular serogroups of the isolates were untypable. Based on histopathological features and bacterial analysis results, the rabbits were diagnosed as P. multocida infection. P. multocida infections might result in considerable economic loss in commercial rabbit production facilities in Korea.
김지현,이경현,정지열,이희,손준형,소병재,최은진,Kim, Ji-Hyeon,Lee, Kyunghyun,Jung, Ji-Youl,Yi, Hee,Sohn, Jun Hyung,So, ByungJae,Choi, Eun-Jin 대한수의학회 2018 大韓獸醫學會誌 Vol.58 No.3
Two 12-month-old cattle with anthelmintics containing trichlorfon the day before death presented to the Animal and Plant Quarantine Agency for diagnosis. In necropsy, they revealed enlargement of the spleens, redness of mucosa and serosa in stomachs and intestines, and friable kidneys. Histopathologically, hemorrhages in the spleens, omasums, abomasums, and intestines as well as renal tubular necrosis were observed. Trichlorfon was detected at above the lethal dose in the ruminal contents. Based on these findings, we diagnosed this case as death caused by trichlorfon poisoning.
이승희,정지열,정재훈,이현경,박중원,이경기,김종완,소병재,윤순식,Lee, Seunghee,Jung, Ji-Youl,Jeong, Jae-Hoon,Lee, Hyunkyoung,Park, Jung-Won,Lee, Kyoung-Ki,Kim, Jong-Hwan,So, ByungJae,Yoon, Soon-Seek 한국동물위생학회 2018 韓國家畜衛生學會誌 Vol.41 No.3
Heat stroke in a dog is a life-threatening syndrome characterized by a high body temperature over $41^{\circ}C$, by the central nervous system dysfunction, and by multiple organ dysfunction. A 11-month-old male American Pit Bull Terrier was presented to clarify the cause of death to diagnostic laboratory. This dog showed clinical signs such as high body temperature ($42^{\circ}C$), severe tachypnea, hematochezia, epistaxis and hemoptysis after transportation at hot summer time. At necropsy, there were hemorrhages in skin, serosa of stomach and small intestine, and also dark red fluid in lumen of intestine. Histopathologic examination revealed extensive hemorrhages in stomach, muscle, skin, and tongue. In microbiology, pathologic bacteria such as Pasteurella, Boedetella, Salmonella, Clostridium, and circulating virus in Korea such as CDV, CIV, CAV, CHV, CCV, CPIV were negative except CPV. There were many gross and microscopic lesions suggesting hest stroke while pathologic agents and related lesions were not detected. Therefore we diagnosed this case as heatstroke.
김지현 ( Ji-hyeon Kim ),이현경 ( Hyunkyoung Lee ),이경현 ( Kyunghyun Lee ),백강현 ( Kanghyun Baek ),최은진 ( Eunjin Choi ),소병재 ( Byungjae So ),양시연 ( Siyeon Yang ) 한국가축위생학회 2016 韓國家畜衛生學會誌 Vol.39 No.3
A 16 year-old female grey pony was presented to Animal and Plant Quarantine agency for diagnosis in Feb 2, 2015. At necropsy, multiple pigmented masses, likely melanomas, were detected peri-anally and under the tail. Further metastatic spread to the spleen, liver, lung and lymph nodes was also identi-fied. Histopathologically, anaplastic and pleomorphic melanocytes were observed in the mass. By im-munohistochemistry, PNL2, S100 and PGP 9.5 protein were detected, but Melan A was not expressed in the neoplastic melanocytes. Based on the pathological and immunohistochemical examination, we di-agnosed this case as malignant melanoma in a grey pony. To the authors` knowledge, this is the first report of equine malignant melanoma in republic of Korea.
정지연 ( Jiyeon Jeong ),이경현 ( Kyunghyun Lee ),최은진 ( Eun-jin Choi ),김지현 ( Ji-hyeon Kim ),소병재 ( Byungjae So ),이승희 ( Seunghee Lee ),신현호 ( Hyunho Shin ),정지열 ( Ji-youl Jung ) 한국동물위생학회(구 한국가축위생학회) 2018 韓國家畜衛生學會誌 Vol.41 No.1
An 11 year-old male Korean short-haired cat was presented to local animal hospital due to weight loss, vomiting, and intestinal hypomotility. After the cat was euthanized by poor clinical outcomes, necropsy was performed at Animal and Plant Quarantine Agency. At necropsy, the stomach was enlarged and had some nearly complete pellet food and the yellow mucous contents. The lumen of the middle and lower parts of the jejunum became narrow. Histopathologically, medium-sized lymphoid cells with hyperchromatic nuclei enclosed by scant cytoplasm were diffusely proliferated from mucosa to serosa of the small intestine. These findings were mainly observed in the jejunum and slightly in the duodenum and ileum. The monomorphous lymphocytes were 1 to 1.5 times larger than red blood cells and had few mitotic figures. Metastasis of the tumor cells to other organs was not observed. In the result of immunohistochemical analysis for identifying the origin of tumor cells, CD3 was expressed, but CD79 was not detected in the infiltrated cells. This case was diagnosed as T cell intestinal lymphoma in a Korean short-haired cat based on the clinical signs, gross findings, histopathology, and immunohistochemistry.
김종호 ( Jongho Kim ),이경현 ( Kyunghyun Lee ),노수권 ( Su Gwon Roh ),조헌호 ( Heon-ho Jo ),소병재 ( Byungjae So ),김희진 ( Heui-jin Kim ) 한국동물위생학회(구 한국가축위생학회) 2021 韓國家畜衛生學會誌 Vol.44 No.1
A 23-month-old Holstein cattle showed excess salivation and reluctance of walking and suddenly died after forced sudden movements. Grossly, numerous fibrous adhesions were present within cranial abdominal cavity including the reticulum and diaphragm and thoracic cavity involving lungs, pericardial sac, and heart. A perforation made by a 10 cm-long sharp-ended wire was detected in the reticulum. Histopathologically, fibrous suppurative epicarditis and myocardial necrosis were observed. Fibrosis with neovascularization were found in lungs, spleen, and liver. And granulomatous reticulitis was observed. For differential diagnosis, no pathogenic bacteria were detected through microbiological tests and PCR results were also negative for bovine susceptible pathogenic antigens. Based on the gross and histopathological examination, we diagnosed this case as chronic traumatic pericarditis. Cattle are inquisitive and prone to swallow various kinds of metallic foreign bodies since they do not use their lips. Therefore, avoiding ingestion of metallic objects in animal feed and animal areas by careful environmental management of farms is required and farmers should give the adequate minerals and vitamins into the feeds not to lick or shallow foreign bodies in case of mineral deficiency. For veterinary practitioners, physical examination, blood tests, and diagnostic imaging (X-ray and Ultrasonography) are required for an exact diagnosis. Furthermore, placing the magnets in rumen would be effective for prophylactic administrations.
김지현 ( Ji-hyeon Kim ),이경현 ( Kyunghyun Lee ),정지열 ( Ji-youl Jung ),양시연 ( Siyeon Yang ),이현경 ( Hyunkyoung Lee ),소병재 ( Byungjae So ),최은진 ( Eunjin Choi ) 한국가축위생학회 2017 韓國家畜衛生學會誌 Vol.40 No.4
Six to seven-month-old 10 beef calves in 140-head beef cattle farm in Gimpo-si, Gyeonggi-do were suffered from ataxia and astasia. Two of them were submitted to Animal and Plant Quarantine Agency for diagnosis in July 9, 2015. At necropsy, the radius and tibia of both calves showed irregular thickening and hemorrhage of the physis in addition to hemorrhage and disruption of trabeculae in metaphysis. Histopathologically the physis showed irregular tongues of cartilage remaining the metaphysis. Disorganization, hemorrhage and fibrosis were observed in metaphyseal and epiphyseal bones. The serum 25-hydroxyvitamin D3 (D3) and calcium levels were lower than normal range. In addition, the serum D3 levels in the other 9 calves of the same farm were lower than normal levels. Based on the pathological examination and serum chemistry measurements, we diagnosed this case as rickets caused by vitamin D deficiency in calves.
흑염소에서의 철쭉으로부터 유래된 그레이아노톡신 중독증 증례
김지현 ( Ji-hyeon Kim ),정지열 ( Ji-youl Jung ),최은진 ( Eunjin Choi ),신은경 ( Eunkyung Shin ),정지연 ( Jiyeon Jeong ),이경현 ( Kyunghyun Lee ),김선춘 ( Suncheun Kim ),소병재 ( Byungjae So ) 한국가축위생학회 2017 韓國家畜衛生學會誌 Vol.40 No.4
A 3 year-old black goat was presented to Animal and Plant Quarantine agency for diagnosis in June, 2017. She was intaken feed with Rhododendron schlippenbachii the day before death. The clinical signs included loss of appetite, lethargy, hypersalivation, astasia, yelling. At necropsy, foamy discharge were observed in the airway. Histologically, foreign body, eosinphil and macrophges was observed in alveolar lumen of lung. Grayanotoxin derived from Rhododendrons was detected in ruminal contents. Based on the pathological and toxine examination, we diagnosed this case as grayanotoxin poisoning in a black goat.