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김선경,조효숙,백희주 복식문화학회 2008 服飾文化硏究 Vol.16 No.6
The purpose of this study was to research the characteristics of the pattern design and the weave construction of 67 fashion fabrics in women's Hanbok. All the fabrics were made by 100% silk. Arrangement, size, and the type of patterns were investigated for research of the pattern characteristics. Pattern weave and background weave were analyzed, then the weight and the thickness were measured for studying the fabric construction. The results were as follows. First, irregular arrangement was more commonly used than regular arrangement, and then the complex arrangement and the combination arrangement were appeared considerably because of the existence of the various patterns in a fabric. Third, the types of pattern weave construction were much more than those of background weave construction. This is caused by the expression of dimensional effect for patterns. This survey can be practically used for development of pattern design for Hanbok industry and furthermore it will contribute to revitalizing of Hanbok market to overcome design limit in the future.
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Long-term follow-up of Fanconi anemia: clinical manifestation and treatment outcome
윤병규,김희나,한의정,장해인,한동균,백희주,황태주,국훈 대한소아청소년과학회 2014 Clinical and Experimental Pediatrics (CEP) Vol.57 No.3
Purpose: The aim of this study was to characterize Korean patients with Fanconi anemia (FA), which isa rare but very challenging genetic disease. Methods: The medical records of 12 FA patients diagnosed at Chonnam National University Hospitalfrom 1991 to 2012 were retrospectively reviewed. Results: The median age at diagnosis was 6.2 years. All patients showed evidence of marrow failureand one or more physical stigmata. Chromosome breakage tests were positive in 9 out of 11 availablepatients. The median follow-up duration was 69.5 months. The Kaplan-Meier (KM) survival of all patientswas 83.3% at 10 years and 34.7% at 20 years, respectively. Seven patients underwent 9 stem celltransplantations (SCTs). Among them, 5 were alive by the end of the study. Ten-year KM survival afterSCT was 71.4% with a median follow-up of 3.4 years. All 5 patients treated with supportive treatmentalone died of infection or progression at the median age of 13.5 years, except for one with short followupduration. Acute leukemia developed in 2 patients at 15.4 and 18.1 years of age. Among 6 patientswho are still alive, 3 had short stature and 1 developed insulin-dependent diabetes mellitus. Conclusion: We provide information on the long-term outcomes of FA patients in Korea. A nation-wideFA registry that includes information of the genotypes of Korean patients is required to further characterizeethnic differences and provide the best standard of care for FA patients.
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박경미,유건희,김성구,이재욱,정낙균,주희영,구홍회,류철주,한승민,한정우,최정윤,홍경택,강형진,신희영,임호준,고경남,김혜리,국훈,백희주,김보람,양의진,임재영,박은실,최은진,박상규,이재민,심예지,김지윤,박지경,공섬김,최영배,조빈,임영탁 대한암학회 2022 Cancer Research and Treatment Vol.54 No.1
Purpose Acute promyelocytic leukemia (APL) is a rare disease in children and there are some different characteristics between children and adult. We aimed to evaluate incidence, clinical characteristics and treatment outcomes of pediatric APL in Korea. Materials and Methods Seventy-nine pediatric APL patients diagnosed from January 2009 to December 2016 in 16 tertiary medical centers in Korea were reviewed retrospectively. Results Of 801 acute myeloid leukemia children, 79 (9.9%) were diagnosed with APL. The median age at diagnosis was 10.6 years (range, 1.3 to 18.0). Male and female ratio was 1:0.93. Thirty patients (38.0%) had white blood cell (WBC) count greater than 10×109/L at diagnosis. All patients received induction therapy consisting of all-trans retinoic acid and chemotherapy. Five patients (6.6%) died during induction chemotherapy and 66 patients (86.8%) achieved complete remission (CR) after induction chemotherapy. The causes of death were three intracranial hemorrhage, one cerebral infarction, and one sepsis. Five patients (7.1%) suffered a relapse during or after maintenance chemotherapy. The estimated 4-year event-free survival and overall survival (OS) rates were 82.1%±4.4%, 89.7%±5.1%, respectively. The 4-year OS was significantly higher in patients with initial WBC < 10×109/L than in those with initial WBC ≥ 10×109/L (p=0.020). Conclusion This study showed that the CR rates and survival outcomes in Korean pediatric APL patients were relatively good. The initial WBC count was the most important prognostic factor and most causes of death were related to serious bleeding in the early stage of treatment. Purpose Acute promyelocytic leukemia (APL) is a rare disease in children and there are some different characteristics between children and adult. We aimed to evaluate incidence, clinical characteristics and treatment outcomes of pediatric APL in Korea.Materials and Methods Seventy-nine pediatric APL patients diagnosed from January 2009 to December 2016 in 16 tertiary medical centers in Korea were reviewed retrospectively.Results Of 801 acute myeloid leukemia children, 79 (9.9%) were diagnosed with APL. The median age at diagnosis was 10.6 years (range, 1.3 to 18.0). Male and female ratio was 1:0.93. Thirty patients (38.0%) had white blood cell (WBC) count greater than 10×109/L at diagnosis. All patients received induction therapy consisting of all-trans retinoic acid and chemotherapy. Five patients (6.6%) died during induction chemotherapy and 66 patients (86.8%) achieved complete remission (CR) after induction chemotherapy. The causes of death were three intracranial hemorrhage, one cerebral infarction, and one sepsis. Five patients (7.1%) suffered a relapse during or after maintenance chemotherapy. The estimated 4-year event-free survival and overall survival (OS) rates were 82.1%±4.4%, 89.7%±5.1%, respectively. The 4-year OS was significantly higher in patients with initial WBC < 10×109/L than in those with initial WBC ≥ 10×109/L (p=0.020).Conclusion This study showed that the CR rates and survival outcomes in Korean pediatric APL patients were relatively good. The initial WBC count was the most important prognostic factor and most causes of death were related to serious bleeding in the early stage of treatment.
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