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배은아,한명주,김은진,김동현 대한약학회 2004 Archives of Pharmacal Research Vol.27 No.1
When ginseng water extract was incubated at 60oC in acidic conditions, its protopanaxadiol ginsenosides were transformed to ginsenoside Rg3 and D20-ginsenoside Rg3. However, protopanaxadiol glycoside ginsenosides Rb1, Rb2 and Rc isolated from ginseng were mostly not transformed to ginsenoside Rg3 by the incubation in neutral condition. The transformation of these ginsenosides to ginsenoside Rg3 and D20-ginsenoside Rg3 was increased by increasing incubation temperature and time in acidic condition: the optimal incubation time and temperature for this transformation was h and 60oC resepectively. The transformed ginsenoside Rg3 and D20-ginsenoside Rg3 were metabolized to ginsenoside Rh2 and D20-ginsenoside Rh2, respectively, by human fecal microflora. Among the bacteria isolated from human fecal microflora, Bacteroides sp., Bifidobacterium sp. and Fusobacterium sp. potently transformed ginsenoside Rg3 to ginsenoside Rh2. Acid-treated ginseng (AG) extract, fermented AG extract, ginsenoside Rh2 and protopanaxadiol showed potent cytotoxicity against tumor cell lines. AG extract, fermented AG extract and protopanaxadiol potently inhibited the growth of Helicobacter pylori.
배은아,한명주 한국식품조리과학회 2001 한국식품조리과학회지 Vol.17 No.3
The objective of this study was to evaluate the effect of functional herbal foods on the growth of intestinal lactic acid bacteria. When Bifidobacterium breve and human intestinal microflora were inoculated in the general anaerobic medium which contained each functional food water extract, most of functional herbal foods induced the growth of lactic acid bacteria by decreasing pH of the broth. The pH decreasing effects of Liriipe platyphylla and Platycodon grandiflorum were excellent. The growth of lactic acid bacteria effectively inhibited the bacterial enzymes, $\beta$-glucosidase and $\beta$ -glucuronidase. Eugenia caryophyllata and Liriipe platyphylla potently inhibited the productivity of P -glucosidase of B. breve and human intestinal bacteria. Cinnamomum cassia, Gardenia jasminoides and Platycodon grandiflorum potently inhibited the productivity of $\beta$-glucuronidase of human intestinal bacteria. The growth component isolated from Platycodon grandiflorum was sucrose (compound B). 1. 약선식품소재의 물추출물 중 pH 저하효과가 가장 큰 것은 B. breve를 배양하였을 경우 Citrus aurantium (진피), Liriipe platyphylla (맥문동), Platycodon grandiflorum (길경), Schizandra chinensis (오미자)였고, 사람의 장내균총을 배양했을 경우는 Angelica gigas (당귀), Hordeum vulgare (맥아), Liriipe platyphylla (맥문동), Platycodon grandiflorum (길경), schizandra chinensis (오미자) 등이었다. 2. 약선식품소재의 $\beta$-glucosidase 효소활성억제효과는 B. breve를 배양했을 경우 Citrus aurantium(진피), Eugenia caryophyllata (정향), Liriipe platyphylla (맥문동), Platycodon grandiflorum (길경), Schizandra chinensis (오미자)가 90%. 이상의 억제효과를 나타내었고 사람의 장내균총에 대해서는 Eugenia caryophyllata (정향), Liriipe platyphylla (맥문동)가 40% 이상의 억제효과를 나타내었다. 3. $\beta$-Glucuronidase 활성을 억제하는 것으로 나타난 약선식품소재는 사람의 장내균총에 대해서는 Cinnamomum cassia(계지), Gardenia jasminoides(치자), Platycodon grandiflorum (길경) 등이였다. 4. 길경으로부터 in vitro에서 유산균증식효과를 나타내는 compound B를 분리하였으며 이 화합물은 기기분석을 한 결과 sucrose임을 밝혀졌으며, 사람의 장내균총에 대한 효과를 측정한 결과 $\beta$-glucosidase활성은 크게 억제하지 못했지만 $\beta$-glucuronidase 및 tryptophnase활성은 각각 49%, 67%의 억제효과를 나타내었다. 또한 사람의 장내우세균인 B. breve를 증식시키는 효과가 있었다.
배은아,이준석,정영진 한국섬유공학회 2001 한국섬유공학회지 Vol.38 No.12
The structural features of fabrics originated from the weaving conditions affect their physical and mechanical properties characterized as tensile, shears bending and compressional properties, etc. In this study, to identify the effect of the weaving condition on fabric hand, samples were classified with various variables such as weft density; weft yarn, and fabric structure. The final 24 fabric samples were prepared under various weaving conditions and subsequent polyester finishing conditions. The fabric mechanical characteristics required for primary hand values were evaluated with the KES-FB system. Thermal analysis, image analysis, and statistical methods were used in investigating the characteristics of the polyester fabrics and identifying the correlation between the weaving condition and the mechanical characteristic values. The weight reduction rate of the fabrics was changed significantly with increasing filament numbers for same denier yarns compared with other variables. The bending and shear rigidities were remarkably affected by the weaving conditions. The result of the hand values represented higher Fukurami values and lower Hari and Koshi values compared with those of KN-202-LDY mean values which is the a general hand value of peach face type fabrics.
Peyer patch 세포에서 임상 빈용생약이 IgA 생산성에 미치는 영향
배은아,한명주,김동현,Bae, Eun-Ah,Han, Myung-Joo,Kim, Dong-Hyun 한국생약학회 2000 생약학회지 Vol.31 No.3
This study was designed to evalulate the biological activity, particularly induction of IgA in primary Peyer's patches cells, of herbal medicines for a long time in Asia. Among fifty four herbal medicines tested, Ephedra sinica, Magnolia officinalis, Lonicera japonica and Lithospermum erythorhizon induced IgA production. The polar and high molecular weight component in Ephedra sinica was capable of inducing IgA in primary Peyer's patches cells. Therefore, we suggest that some herbal medicines could use for the treatment of food allergy.
배은아,한명주 경희대학교 생활과학연구소 1997 생활과학논집 Vol.1 No.1
Six hundred fifty people in Seoul and Bundang area were surveyed for conumer opinions about mushroom from Jan., 1995 to Feb., 1995. The result of this study showed that the preparation method of mushroom were the following: stir-frying(73.1%), boiling(17.9%), pan frying(5.3%), drink(1.8%) and frying(0.6%). Majority of respondants(90.8%) ate mushroom 1-2 times per month. Respondants preferred to eat Lentinus edodes(36.5%), Agaricus bisporusar, albidus(22.8%) and Pleurotus ostreatus(21.8%). The reason for eating mushroom were the following, from most to least frequence: 'prevention of chronic illness'. 'antitumor', 'low calorie food', 'containing protein', 'containing vitamin'. The respondent perception on the desease preventive effect of mushrooms were slightly higher(p=0.0698) in female than male, but not affected by gender, age and occupation.