o-Chlorobenzylidenemalononitrile의 가수분해 및 분석에 관한 연구

박성우,김남이,김동환,홍성욱,성낙도,김일광,오인교,Park, Sung-Woo,Kim, Nam-Yee,Kim, Dong-Hwan,Hong, Sung-Work,Sung, Nack-Do,Kim, Il-Kwang,Oh, In-Kio 한국분석과학회 1992 분석과학 Vol.5 No.4

o-Chlorobenzylidenemalononitrile(CS), chloroacetophenone 및 bromophenylacetonitrile의 이성질체와 같은 최루 자극성 물질들의 가수분해, 산화, 환원, 열분해 및 대사에 의한 화합물의 분석은 법과학적 측면에서 주요한 의미가 있다. 본 실험에서는 10% MeOH-$H_2O$ 및 10% dioxane-$H_2O$ 용액에서 pH 1.0~11.0과 온도 변화에 따른 CS의 가수분해 조건을 검토하고 가수분해 생성물이 o-chlorobenzaldehyde와 malononitrile임을 분광학적 방법 및 전기화학적 방법에 의해 확인하였다. The analysis, hydrolysis mechanism, oxidation, reduction, thermal decomposition and metabolism of irritant materials such as chloroacetophenone isomers, bromophenylacetonitrile isomers, o-chlorobenzylidenemalononitrile(CS), and ethylisothiocyanate, etc. are interested in forensic science. We had studied hydrolysis of CS in 10% MeOH-$H_2O$ and 10% dioxane-$H_2O$ at pH 1.0~11.0 and various temperatures. As a result, we identified o-chlorobenzaldehyde and malononitrile that were formed by hydrolysis of CS by using gas chromatography/mass spectrometry, UV/Vis spectrometry, and polarographic method.

정자형성 과정에서 Vascular Endothelial Growth Factor 및 Endothelin-1 발현의 면역조직화학적 연구

박성우,박현준,박남철,Park, Sung-Woo,Park, Hyun-Jun,Park, Nam-Cheol 대한생식의학회 2004 Clinical and Experimental Reproductive Medicine Vol.31 No.4

Objective: The effects on spermatogenesis by expression of vascular endothelial growth factor (VEGF) and endothelin-1 (ET-1) were investigated. Materials and Methods: Testicular specimens were obtained from 40 infertile males due to primary testicular failure and from 10 fertile males with other urologic problems. The specimens of infertile males were devided into 4 groups according to histologic findings; Sertoli cell only syndrome (A), maturation arrest (B), hypospermatogenesis (C) and sloughing and disorganization (D). VEGF and ET-1 expression were detected with immunohistochemical stain. Results: VEGF expression on Leydig cell was detected in all cases. But, VEGF expression rates on germ cell were significantly higher in infertile group B, C, D compared to that of the control group (p<0.05). ET-1 expression rates on Leydig cell was significantly lower in all infertile group compared to that of the control group (p<0.05). But, ET-1 expression rates on Sertoli cell was significantly higher in all infertile group compared to that of the control group (p>0.05). In germ cell of infertile group, LH, FSH and prolactin were significantly decreased, and estradiol is increased in positive stain group on ET-1 immunohistochemical stain (p<0.05). VEGF and ET-1 expression were not correlated mean seminiferous tubule diameter (p>0.05). Conclusions: Abnormal spermatogenesis would be reflected in VEGF expression in germ cell.

Triethylgermyldiphenylphosphine과 Phenylisocyanate의 반응

박성우,이일규,Sung Woo Park,Il Kyu Lee 대한화학회 1983 대한화학회지 Vol.27 No.1

Triethylgermyldiphenylphosphine과 phenylisocyanate를 1:10 mole 비로 ampoule 속에서 혼합하여 여러 온도에서 반응시켰다. 그 결과 $0^{\circ}C$에서는 phenylisocyanate의 고리화 2합체인 N, N-diphenyluretidine-2,4-dione만이, $20^{\circ}C$에서는 phenylisocyanate의 고리화 3합체인 triphenylisocyanurate가 함께 생성되었으며, $50^{\circ}C$에서는 위의 생성물 이외에 diphenylcarbodiimide가 생성되었다. 또한 $100^{\circ}C$이상에서는 2합체는 생성되지 않고, diphenylcarbodiimide와 1,3,5-triphenyl-2,4,6-tris(phenylimino) hexahydro-1,3,5-triazine이 주로 생성되었다. 그리고 Triethylgermyldiphenylphosphine은 상기 고리 화합물들의 생성에 촉매로 작용하였다. Triethylgermyldiphenylphosphine was reacted with phenylisocyanate at various temperatures for three days in sealed ampoules. At $0^{\circ}C$, only N, N-diphenyluretidine-2,4-dione, a cyclic dimer of phenylisocyanate (35%), was formed. But at $20^{\circ}C$, phenylisocyanutrate, a cyclic trimer of phenylisocyanate (30%), was formed along with the dimer. At $50^{\circ}C$, diphenylcarbodiimide (55%) was given together with the compounds described above. At the higher reaction temperatures than $100^{\circ}C$, instead of the dimer and trimer of phenylisocyanate, 1,3,5-triphenyl-2,4,6-tris(phenylimino) hexahydro-1,3,5-triazine, a cyclic trimer of diphenylcarbodiimide (30%) and diphenylcarbodiimide (70%) were mainly produced. Triethylgermyldiphenylphosphine appears to act as a catalyst for the formation of the above cyclic compounds.

토양세정 기술을 활용한 윤활유와 아연 복합오염 철도토양의 정화 연구

박성우,조정민,이재영,박준규,백기태,Park, Sung-Woo,Cho, Jung-Min,Lee, Jae-Young,Park, Joon-Kyu,Baek, Ki-Tae 한국지하수토양환경학회 2011 지하수토양환경 Vol.16 No.4

The feasibility study of soil flushing was investigated to remediate lubricant oil and zinc contaminated railway soil. In this study, mixed washing agents of surfactant and inorganic acid/base were used for the simultaneous removal. The mixed washing agent of non-ionic surfactant and HCl removed 15% of the lubricant oil and 40% of zinc, respectively. Alkaline-enhanced soil washing process increased the removal of lubricant oil up to 40%. This is because alkaline solution reduced the interfacial tension between water phase and lubricant oil phase due to the soap formation reaction. To simulate in-situ soil flushing for the remediation of railroad-related contamination, two dimensional soil flushing was carried out based on the results of batch soil washing. In the soil flushing, the removal efficiencies of lubricant oil and zinc were 34% and 16%, respectively. Even though the removal efficiency was low, the mixed washing agent can remove metal and lubricant oil simultaneously.

우울증과 항우울작용에 관한 p11(S100A10)의 역할

박성우,서미경,이정구,김영훈,Park, Sung Woo,Seo, Mi Kyong,Lee, Jung Goo,Kim, Young Hoon 대한생물정신의학회 2016 생물정신의학 Vol.23 No.1

p11 protein (S100A10) is downregulated in depressive-like states of human and rodent. Antidepressant drug treatment increases p11 levels in rodent models. We reviewed studies demonstrating that p11 levels are regulated in depression and by antidepressant treatment and that p11 upregulation exerts antidepressant effects. Current studies on p11 underscore the importance of p11 as a potential antidepressant target.

Electric Heat Tracing을 위한 Zigbee 기반 통합 감시제어 시스템의 개발 및 검증

박성우,박순응,Park, Sung-Woo,Park, Sun-Eng 한국전자통신학회 2015 한국전자통신학회 논문지 Vol.10 No.12

'스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

Electric heat tracing 시스템은 플랜트 내 각종 배관의 온도를 관리하는 시스템이다. 본 논문에서는 electric heat tracing 시스템을 통합적으로 감시하고 제어하기 위한 TESCON(: TEmperature Sensing and CONtrol) 시스템을 제안한다. TESCON 시스템에서 디바이스간의 정보 교환은 Zigbee 네트워크 기반의 무선 방식으로 이루어진다. TESCON 시스템의 성능 분석을 위해 컴퓨터 시뮬레이션을 수행하였다. 테스트베드를 통해서도 비슷한 결과를 얻음으로써 TESCON 시스템의 유효성을 입증하였다. 또한, 계층적 트리 토폴로지를 기반으로 하는 네트워크 분할, 채널 재사용, 프레임 집약 기법 등을 적용한 시스템 확장 방안도 제시하였다. An electric heat tracing system manages the temperature of pipes used in a plant. We propose a Zigbee-based wireless system so called the TESCON(: TEmperature Sensing and CONtrol) to monitor and control the electric heat tracing system in an integrated way. Simulations have been done to analyze the performance of the TESCON system. The performance of the TESCON system is validated by obtaining similar results via testbed operation. We also suggest an extension method of the TESCON system based on the hierarchical tree topology by adopting techniques such as network partition, channel reuse and frame aggregation.

이동 평균법을 이용한 고층 건물의 부등축소량 보정 기법

박성우,최세운,박효선,Park, Sung-Woo,Choi, Se-Woon,Park, Hyo-Seon 한국전산구조공학회 2010 전산구조공학 Vol.23 No.4

시간이 지남에 따라 건물의 수직부재가 수축하는 것을 기둥축소라고 한다. 건물의 고층화 및 비정형화 추세 때문에 수직부재들에 작용하는 축하중 크기 간의 차이를 피할 수 없게 되며, 이의 영향으로 인접 수직부재 간의 축방향 축소량이 차이가 나게 된다. 이러한 부등축소량은 수직부재와 수평부재의 접합부에 추가적인 응력을 유발시키거나 슬래브의 기울어짐 또는 간벽이나 창호 등 비구조재의 사용성에 문제를 초래하게 된다. 이러한 부등축소량의 영향을 감소시키기 위하여 시공 중 수직부재의 설치 시 예측된 보정을 하게 된다. 보정의 합리성은 각 부재별 축소량의 정확한 예측과 예측된 축소량을 이용한 각 부재들의 합리적 보정량 산정에 있다. 부등축소량의 예측은 점점 더 정확해지고 있으나 보정 기법에 관한 연구는 거의 없다. 따라서 본 논문에서는 이동 평균법을 사용한 보정 기법과 보정하면서 발생하는 오차에 대한 합리적인 제한조건을 제시하였으며, 제한조건의 변화와 보정 그룹 수의 관계를 살펴봄으로써 제한조건 설정의 객관적인 판단 기준이 되었다. 그리고 이전에 연구되어진 SA 알고리즘을 사용한 최적 보정 기법과 결과를 비교해 봄으로써 이동 평균법 보정 기법의 효과를 검증하였다. The vertical members of structures are shortened as time goes on. Because structures have been high-rising and atypical there should be different axial loads among vertical members and it causes differential column shortenings. The differential column shortening add stresses to connections, make slab tilt, and damage to non-structural components. To reduce these influences compensation is need. The rational compensation means the exact expectation of amounts of column shortenings and the reasonable corrections. The expectation of column shortenings are more exact as researched, however, there is little research about the compensation. This paper presents the average correction method and the constraints for differential column shortenings considering errors due to the construction precision. The relations between constraints and the number of correction groups give an objective criterion for decision of constraints.

폭약류의 법과학적 분석 (II)

박성우,김동환,유재훈,Park, Sung-Woo,Kim, Dong-Hwan,You, Jae-Hoon 한국분석과학회 1998 분석과학 Vol.11 No.3

삽입형 평면 트러스를 이용한 철근콘크리트 무량판 구조의 슬래브-기둥 접합부 전단보강 공법

박성우,강수민,김효락,Park, Sung-Woo,Kang, Soo-Min,Kim, Hyo-Rak 한국공간구조학회 2012 한국공간구조학회지 Vol.12 No.2

$\beta$-glucan을 접종한 한국산 메기(Silurus asotus)의 호중구와 리소자임 활성 증강

박성우,김영길,최동림,Park, Sung-Woo,Kim, Young-Gill,Choi, Dong-Lim 한국어병학회 1996 한국어병학회지 Vol.9 No.1

한국산 메기(Silurus asotus)에 $\beta$-glucan을 복강내에 접종한 후, 경시적으로 말초혈액중의 호중구의 수와 PAS반응의 변화, 호중구의 탐식능 및 혈청중의 리소자임의 활성변화를 지표로 비특이적방어능력의 증강유무를 조사하였다. 글루칸의 투여후 말초혈액중의 호중구수를 증가시켰으며 투여회수에 따라 2회 접종한 경우 호중구의 증가가 지속되는 기간이 1회 접종어보다 길게 나타났다. 그러나 호중구의 PAS반응에는 변화가 없었다. 또 탐식율도 현저하게 증가하였지만 탐식지수는 변화가 없었다. 리소자임의 활성은 2회 접종시만이 현저히 증가하였으나 1회 접종시에는 활성의 증가가 없었다. 그러므로 $\beta$-glucan의 투여는 말초혈액중의 호중구수와 탐식능의 증가 및 리소자임 활성의 증가등 비특이적방어인자의 활성을 증가시켜 어체를 방어하는 능력을 증강시키는 것임을 알 수 있다. To examine the effectiveness of $\beta$-glucan in non-specific defence mecanisms of Korean catfish(Silurus asotus), the activities of peripheral neutrophils and serum lysozyme were evaluated after once or twice $\beta$-glucan injections. The number of peripheral neutrophils increased after the injection. The increased number in neutrophils in twice $\beta$-glucan injections maintained longer than in single glucan injecton. But the neutrophils did not showed any remarkable changes in PAS-positive reaction. Peripheral neutrophils from fish injected glucan had enhanced phagocytic activities but there was no significant difference in phagocytic index for the glucan and control groups. An elevation of lysozome activity was also observed in the fish received twice glucan but neither single glucan or physiological saline injection could not evoked an increase of lysozyme activity. These results suggest that $\beta$-glucan can enhance the resistance of Korean catfish against to bacteria infection through the activation of peripheral neutrophils and lysozyme.