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박무진,진소리,오은제,송우섭,이현석,황규현,오승주,주아라,백수인,Park, Mu-jin,Jin, So-ri,Oh, Eun-jae,Song, Woo-sub,Lee, Hyun-seok,Hwang, Kyu-hyun,Oh, Seung-ju,Ju, Ah-ra,Baek, Su-in 대한한방내과학회 2021 大韓韓方內科學會誌 Vol.42 No.5
Objective: This study investigated the efficacy of using Nokyonggunbi-tang and other Korean medical treatments for a patient with consumptive disease and chronic fatigue. Methods: A 59-year-old female patient with fatigue, headache, dizziness, and neck pain due to consumptive disease and chronic fatigue was treated with herbal medicine (Nokyonggunbi-tang), together with acupuncture, pharmacopuncture, cupping, and chuna manual therapy, for 22 days. The treatment effects on the pain were evaluated using the scores for the Fatigue Severity Scale (FSS), European Quality of Life Five Dimensions (EQ-5d) Scale, Neck Disability Index (NDI), and Numerical Rating Scale (NRS). Results: Following treatment, the patient showed a decrease in the FSS, NDI, and NRS scores and an improvement in the EQ-5d score. Conclusions: Nokyonggunbi-tang and Korean medical treatment significantly improved fatigue symptoms in a patient with no substrate disease.
소뇌동맥 경색으로 발생한 말초성 안면마비 환자에 대한 한방통합치료 증례보고
박무진,진소리,오은제,오주희,송우섭,이현석,우재혁,황규현,배건희,윤영찬 대한한방내과학회 2022 大韓韓方內科學會誌 Vol.43 No.2
Objective: This study investigates the efficacy of Korean medical treatment for a patient with peripheral facial palsy caused by cerebellar artery infarction. Methods: A 45-year-old male patient with right facial palsy and left side numbness from cerebellar artery infarction was treated with herbal medicine (ligigeopoongsan), acupuncture, pharmacopuncture, and cupping therapy for 37 days. The effects were evaluated using the House-Brackmann (H-B) and Yanagihara’s unweighted grading systems. Results: Following treatment, the patient’s H-B grade decreased and Yanagihara score improved. Conclusion: Korean medical treatment improved peripheral facial palsy in a patient with cerebellar artery infarction.
이무진,정호경,김민석,장지훈,심미옥,김태묵,박호,안병관,조현우,조정희,정원석,김종춘 한국실험동물학회 2016 Laboratory Animal Research Vol.32 No.3
Dendrobium moniliforme (L.) Sw., an herb of the Orchidaceae family, has long been used in traditional medicine to strengthen bones, nourish the stomach, and promote the production of bodily fluid. Recently, polysaccharides isolated from Dendrobium have been used in functional foods and nutraceutical products. A traditional method to process Dendrobium is to soak fresh stems in an ethanol solution, which is the most important factor to ensure high yields of aqueous-extractable polysaccharides. The present study was carried out to investigate the potential acute toxicity of D. moniliforme aqueous extract (DMAE), by a single oral dose in Sprague-Dawley rats. The test article was orally administered once by gavage to male and female rats at doses of 0, 2,500, and 5,000 mg/kg body weight (n=5 male and female rats for each dose). Throughout the study period, no treatment-related deaths were observed and no adverse effects were noted in clinical signs, body weight, food consumption, serum biochemistry, organ weight, or gross findings at any dose tested. The results show that a single oral administration of DMAE did not induce any toxic effects at a dose below 5,000 mg/kg in rats, and the minimal lethal dose was considered to be over 5,000 mg/kg body weight for both sexes. With respect to cytotoxicity, the cell viability of human embryonic kidney (HEK293) cells was less than 50% when the cells were treated with 10 mg/mL aqueous extract for 24 h.
박병후,백무진 대한이비인후과학회 2019 대한이비인후과학회지 두경부외과학 Vol.62 No.9
Malignancy of the middle ear is rare and its estimated incidence is 0.18 cases per million peoplein the US, with its most common type being squamous cell carcinoma. Squamous cell carcinomain situ is thought to be a precursor to squamous cell carcinoma, which is extremelyrare in the middle ear. The pathology reports of squamous cell carcinoma have not been wellcharacterizedas it has not been reported to date in Korea. Here, we report a case of squamouscell carcinoma in situ of the middle ear in a 66-year-old man, who presented with otorrhea andtympanic membrane perforation.
상악동 기원의 반전성 유두종의 수술법에 따른 결과 비교: 전누골와 접근법과 Caldwell-Luc 접근법
박영준,박병후,서태경,김미라,김상연,김신혜,백무진,강명주,김용완 대한이비인후과학회 2021 대한이비인후과학회지 두경부외과학 Vol.64 No.3
Background and Objectives Endoscopic prelacrimal recess approach (PLRA) was introducedto treat maxillary sinus inverted papilloma (IP) without sacrificing the inferior turbinateand nasolacrimal duct. This study aimed to compare surgical outcomes of prelacrimal recessapproach with the conventional Caldwell-Luc approach (CLA) to remove IP of maxillary sinusand to evaluate the usefulness of the PLRA. Subjects and Method We retrospectively reviewed medical records of 51 patients who weretreated in our institution for IP of nasal cavity and sinuses between March 2010 and June 2019. Twenty patients had maxillary sinus IP. Sixteen patients underwent endoscopic sinus surgerycombined with either CLA (n=8) or PLRA (n=8). Demographic data, surgical technique, site ofIP origin, intra- and postoperative complications, duration of follow-up, recurrence rate andpathologic diagnosis were reviewed. Results IP was the pathologic diagnosis for all 16 cases. Gross total removal was achieved inall cases. The mean follow-up period was 20.1 months in CLA group and 12.5 months in PLRAgroup. There was one case of massive bleeding during operation requiring transfusion and postoperativeICU care in CLA group. On postoperative follow-up, two patients from the CLAgroup had recurrence during the follow-up period. One patient had numbness around the gingivalarea, another patient had transient wound dehiscence, and another had persistent oro-antralfistula. In PLRA group, one patient had periorbital swelling after blowing nose; otherwise, noother patient from the PLRA group developed subjective complaints after surgery. Conclusion Endoscopic prelacrimal recess approach showed lower complication rates andrecurrence rates compared to CLA. PLRA is a safe and effective method for the excision of primarymaxillary sinus IP.
다낭신의 중의치료에 대한 임상연구 동향 - CNKI검색을 중심으로
주아라,박미소,최요섭,추원정,백혜경,박무진,Ju, Ah-ra,Park, Mi-so,Choi, Yo-sup,Choo, Won-jung,Baek, Hye-kyung,Park, Mu-jin 대한한방내과학회 2021 大韓韓方內科學會誌 Vol.42 No.3
Objective: This research reviews and investigates the trends in recent clinical studies of polycystic kidney disease (PKD) in China. Method: We searched for clinical studies discussing Oriental medicine-based treatments for PKD in the China National Knowledge Infrastructure (CNKI) database. Thirteen clinical articles published from 2001 to 2019 were analyzed. The search focused on the authors, publication year, type of study, purposes of study, method and duration of treatment, evaluation criteria, and results of the selected articles. Results: Of the articles from the database, 9 case series and 4 randomized controlled trials (RCTs) were analyzed. Ten articles used herbal medicine; 4 used herbal medicine for external use. Gamigyejibokryeong-hwan was the most common herbal prescription. The most frequently used herb was Polia Sclerotium (茯苓), and Cnidii Rhizoma (川芎) was employed in all the external uses. All 13 studies confirmed the efficacy of Oriental medicine treatments. Conclusion: 1. Scientifically designed and more varied clinical studies are required to develop treatments for PKD. 2. The current study could be used as basic data in future clinical studies on treatment and further studies of PKD.